There are currently 601 clinical trials in Sacramento, California looking for participants to engage in research studies. Trials are conducted at various facilities, including University of California Davis Comprehensive Cancer Center, University of California Davis Medical Center, University Of California Davis and Sutter Medical Center Sacramento. Whether you're a healthy volunteer looking to participate in paid medical research or seeking trials related to a specific condition, the city provides a diverse range of opportunities near you.
The Acute Burn ResUscitation Multicenter Prospective Trial
NCT04356859
Recruiting
This is a prospective randomized multi-center study which will compare acute fluid resuscitation using a colloid strategy (LR + 5% Albumin) to a crystalloid strategy (LR alone), in adults with an acute burn involving at least 25% of their total body surface area.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
01/31/2024
Locations: University of California Davis, Regional Burn Center, Sacramento, California
Conditions: Burn Injury
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STAT: Standard Therapy Plus Active Therapy
NCT04368117
Recruiting
The objective of the study is to assess the efficacy of STAT, an activity-based therapy protocol compared to standard therapy (ST) to improve functional outcome and reduce disability in patients recovering from burn injury. This randomized multi-center trial is designed with two parallel treatment groups: STAT and ST. Efficacy of the STAT protocol will be determined through comparison to the ST only group. It will be conducted at seven burn centers.
Gender:
ALL
Ages:
Between 18 years and 65 years
Trial Updated:
01/31/2024
Locations: University of California Davis Medical Center-Regional Burn Center, Sacramento, California
Conditions: Burn Injury, Physical Injury, Thermal Burn
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Characterization of the Melanoma-Specific Immune Response
NCT00368615
Recruiting
The aim of this study is to study T-cells. Blood will be collected and the samples will be used to generate T cell clones. Two separate blood draws will be required at the maximum.
Gender:
ALL
Ages:
Between 18 years and 85 years
Trial Updated:
01/19/2024
Locations: University of California, Davis Department of Dermatology, Sacramento, California
Conditions: Melanoma
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The Rapid Diagnosis of MCI and Depression in Patients Ages 60 and Over
NCT06011681
Recruiting
Mild cognitive impairment (MCI) leading to Alzheimer's disease and related disorders (ADRD) represents a significant health and economic burden of the rapidly expanding senior population. The accurate detection and diagnosis of MCI and its common comorbidity, late-life depression (LLD), is essential for prolonging patient quality of life and developing advancements in research and treatment options. The purpose of the proposed program is to refine Miro Health's A.I. to accurately detect, differe... Read More
Gender:
ALL
Ages:
60 years and above
Trial Updated:
01/18/2024
Locations: Miro Health, Sacramento, California
Conditions: Depression, Mild Cognitive Impairment
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Coflex PS3 Actual Conditions for Use Study
NCT02555280
Recruiting
A 2 and 5 year evaluation of clinical outcomes in the treatment of degenerative spinal stenosis with concomitant low back pain by decompression with additional stabilization using the coflex® Interlaminar Technology for FDA Actual Conditions of Use Study.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
01/04/2024
Locations: Sutter Health, Sacramento, California
Conditions: Spinal Stenosis Lumbar
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A Registry of Subjects With Primary Indeterminate Lesions or Choroidal Melanoma
NCT03941379
Recruiting
The purpose of this observational research study is to follow participants who have been treated with either bel-sar or received alternate treatment (sham, standard of care therapy, etc.) while participating in a previous Aura Biosciences clinical research study to assess the long-term safety and effectiveness in these subjects. This study will collect information from procedures conducted as part of routine follow-up eye care and cancer care. Additionally, the registry will collect all adverse... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
12/20/2023
Locations: Retina Consultants of Sacramento, Sacramento, California
Conditions: Choroidal Melanoma, Indeterminate Lesions of Eye
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Evaluation of the Effectiveness of Nail Genesis DLSO Product for Onychomycosis
NCT06074315
Recruiting
This is a Pre-IDE, prospective, multicenter, randomized, parallel-group, double-blind, vehicle- controlled study to evaluate safety and effectiveness of Nail Genesis DLSO Product for the treatment of DLSO compared with vehicle in infected great toenails in a total of 338 males and non-pregnant, non-lactating, females between 18 and 65 years of age (inclusive). Subjects will be randomized in a 2:1 ratio to receive either Nail Genesis DLSO Product or vehicle. Subject eligibility will be determine... Read More
Gender:
ALL
Ages:
Between 18 years and 65 years
Trial Updated:
12/06/2023
Locations: Northern California Research, Sacramento, California
Conditions: Distal Lateral Subungual Onychomycosis, Onychomycosis
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Enzalutamide and Indomethacin in Treating Patients With Recurrent or Metastatic Hormone-Resistant Prostate Cancer
NCT02935205
Recruiting
This phase I/II trial studies the side effects of enzalutamide and indomethacin and to see how well they work in treating patients with prostate cancer that does not respond to treatment with hormones, has come back, or has spread from where it started to other places in the body. Androgens can cause the growth of prostate cancer cells. Hormone therapy using enzalutamide and indomethacin may fight prostate cancer by lowering the amount of androgen the body makes and/or blocking the use of androg... Read More
Gender:
MALE
Ages:
19 years and above
Trial Updated:
11/28/2023
Locations: University of California Davis Comprehensive Cancer Center, Sacramento, California
Conditions: Metastatic Prostate Carcinoma, Recurrent Prostate Carcinoma, Stage IV Prostate Cancer
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Point-of-Care Ultrasound for Pediatric Thoracic Trauma: A Multi-Institutional Trial
NCT05025150
Recruiting
The objective of the proposed study is to investigate the diagnostic accuracy of ED POCUS in pediatric traumatic thoracic injuries including traumatic pneumothorax, hemothorax, lung contusion, rib fractures, and pulmonary edema (from submersion injury). This will be a prospective, multicenter, observational study of children 0-21 years of age presenting to the participating pediatric emergency departments for suspected traumatic thoracic injury. Results of POCUS will be compared to that of chest... Read More
Gender:
ALL
Ages:
Between 0 years and 21 years
Trial Updated:
11/26/2023
Locations: Sutter Medical Center Sacramento, Sacramento, California
Conditions: Trauma Chest, Pediatric ALL
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Correlation Between Objective Skin Pigment Measurement and Fitzpatrick Skin Type
NCT06144541
Recruiting
The purpose of this study is to correlate subjective skin pigment measurements as reported by patient-responses to the Fitzpatrick Skin Type Scale versus objective classification of skin pigment utilizing Individual Typology Angle (ITA) measurements.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
11/21/2023
Locations: Integrative Skin Science & Research, Sacramento, California
Conditions: Skin Pigment
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Treatment of PAF With the Synaptic System
NCT05905835
Recruiting
Enrolled subjects will be treated with the Synaptic Cryoablation System. Treatment will include cryoablation of the pulmonary veins to achieve PVI. All subjects will be followed for twelve (12) months after completion of the index ablation procedure.
Gender:
ALL
Ages:
Between 18 years and 80 years
Trial Updated:
11/09/2023
Locations: Mercy General Hospital, Sacramento, California
Conditions: Paroxysmal Atrial Fibrillation
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LOcally ABLatIve ThErapy for OligopRogressive Lung And Thoracic MalignanciEs (OBLITERATE)
NCT06103682
Recruiting
This is a phase 2 pragmatic study that evaluates the clinical benefit of continuing systemic therapy with the addition of locally ablative therapies for oligo-progressive solid tumors as the primary objective. The primary outcome measure is the time to treatment failure (defined as time to change in systemic failure or permanent discontinuation of therapy) following locally ablative therapy.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
10/27/2023
Locations: University of California, Davis, Sacramento, California
Conditions: Non-small Cell Lung Cancer, Oligoprogressive, Small-cell Lung Cancer
Register for Updates