There are currently 598 clinical trials in Sacramento, California looking for participants to engage in research studies. Trials are conducted at various facilities, including University of California Davis Comprehensive Cancer Center, University of California Davis Medical Center, University Of California Davis and Sutter Medical Center Sacramento. Whether you're a healthy volunteer looking to participate in paid medical research or seeking trials related to a specific condition, the city provides a diverse range of opportunities near you.
A Registry of Subjects With Primary Indeterminate Lesions or Choroidal Melanoma
NCT03941379
Recruiting
The purpose of this observational research study is to follow participants who have been treated with either bel-sar or received alternate treatment (sham, standard of care therapy, etc.) while participating in a previous Aura Biosciences clinical research study to assess the long-term safety and effectiveness in these subjects. This study will collect information from procedures conducted as part of routine follow-up eye care and cancer care. Additionally, the registry will collect all adverse... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
12/20/2023
Locations: Retina Consultants of Sacramento, Sacramento, California
Conditions: Choroidal Melanoma, Indeterminate Lesions of Eye
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Evaluation of the Effectiveness of Nail Genesis DLSO Product for Onychomycosis
NCT06074315
Recruiting
This is a Pre-IDE, prospective, multicenter, randomized, parallel-group, double-blind, vehicle- controlled study to evaluate safety and effectiveness of Nail Genesis DLSO Product for the treatment of DLSO compared with vehicle in infected great toenails in a total of 338 males and non-pregnant, non-lactating, females between 18 and 65 years of age (inclusive). Subjects will be randomized in a 2:1 ratio to receive either Nail Genesis DLSO Product or vehicle. Subject eligibility will be determine... Read More
Gender:
ALL
Ages:
Between 18 years and 65 years
Trial Updated:
12/06/2023
Locations: Northern California Research, Sacramento, California
Conditions: Distal Lateral Subungual Onychomycosis, Onychomycosis
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Enzalutamide and Indomethacin in Treating Patients With Recurrent or Metastatic Hormone-Resistant Prostate Cancer
NCT02935205
Recruiting
This phase I/II trial studies the side effects of enzalutamide and indomethacin and to see how well they work in treating patients with prostate cancer that does not respond to treatment with hormones, has come back, or has spread from where it started to other places in the body. Androgens can cause the growth of prostate cancer cells. Hormone therapy using enzalutamide and indomethacin may fight prostate cancer by lowering the amount of androgen the body makes and/or blocking the use of androg... Read More
Gender:
MALE
Ages:
19 years and above
Trial Updated:
11/28/2023
Locations: University of California Davis Comprehensive Cancer Center, Sacramento, California
Conditions: Metastatic Prostate Carcinoma, Recurrent Prostate Carcinoma, Stage IV Prostate Cancer
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Point-of-Care Ultrasound for Pediatric Thoracic Trauma: A Multi-Institutional Trial
NCT05025150
Recruiting
The objective of the proposed study is to investigate the diagnostic accuracy of ED POCUS in pediatric traumatic thoracic injuries including traumatic pneumothorax, hemothorax, lung contusion, rib fractures, and pulmonary edema (from submersion injury). This will be a prospective, multicenter, observational study of children 0-21 years of age presenting to the participating pediatric emergency departments for suspected traumatic thoracic injury. Results of POCUS will be compared to that of chest... Read More
Gender:
ALL
Ages:
Between 0 years and 21 years
Trial Updated:
11/26/2023
Locations: Sutter Medical Center Sacramento, Sacramento, California
Conditions: Trauma Chest, Pediatric ALL
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Correlation Between Objective Skin Pigment Measurement and Fitzpatrick Skin Type
NCT06144541
Recruiting
The purpose of this study is to correlate subjective skin pigment measurements as reported by patient-responses to the Fitzpatrick Skin Type Scale versus objective classification of skin pigment utilizing Individual Typology Angle (ITA) measurements.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
11/21/2023
Locations: Integrative Skin Science & Research, Sacramento, California
Conditions: Skin Pigment
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Treatment of PAF With the Synaptic System
NCT05905835
Recruiting
Enrolled subjects will be treated with the Synaptic Cryoablation System. Treatment will include cryoablation of the pulmonary veins to achieve PVI. All subjects will be followed for twelve (12) months after completion of the index ablation procedure.
Gender:
ALL
Ages:
Between 18 years and 80 years
Trial Updated:
11/09/2023
Locations: Mercy General Hospital, Sacramento, California
Conditions: Paroxysmal Atrial Fibrillation
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LOcally ABLatIve ThErapy for OligopRogressive Lung And Thoracic MalignanciEs (OBLITERATE)
NCT06103682
Recruiting
This is a phase 2 pragmatic study that evaluates the clinical benefit of continuing systemic therapy with the addition of locally ablative therapies for oligo-progressive solid tumors as the primary objective. The primary outcome measure is the time to treatment failure (defined as time to change in systemic failure or permanent discontinuation of therapy) following locally ablative therapy.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
10/27/2023
Locations: University of California, Davis, Sacramento, California
Conditions: Non-small Cell Lung Cancer, Oligoprogressive, Small-cell Lung Cancer
Register for Updates
Patient-Derived Xenografts to Reduce Cancer Health Disparities
NCT04410302
Recruiting
This trial establishes patient-derived cancer xenografts in addressing cancer health and treatment disparities that disproportionately affect racial/ethnic minorities. Understanding the genetic and response differences among racial/ethnic minorities may help researchers enhance the precision of therapeutic treatments.
Gender:
ALL
Ages:
Between 21 years and 100 years
Trial Updated:
10/12/2023
Locations: University of California Davis Comprehensive Cancer Center, Sacramento, California
Conditions: Bladder Carcinoma, Gastric Carcinoma, Liver and Intrahepatic Bile Duct Carcinoma, Lung Carcinoma, Malignant Neoplasm
Register for Updates
ABL90 Flex Plus Method Comparison Study_Adults
NCT06078956
Recruiting
The goal of this clinical trial is to validate performance claims for method comparison for the ABL90 FLEX PLUS for pH, pCO2, pO2, cCa2+, cCl-, cK+, cNa+, cGlu, cLac, ctHb, sO2, FO2Hb, FMetHb, FCOHb and FHHb in heparinized whole blood in a Point of Care (POC) setting.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
10/09/2023
Locations: UC Davis, Sacramento, California
Conditions: Diagnostic Test
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Study of Skin Balancing Gel Cream Safety and Influence of Skin Microbiome on Acne Prone Skin
NCT05941065
Recruiting
The purpose of this study is to assess the safety of the skin balancing gel cream and examine the effects it has on the skin microbiome of individuals with non-cystic acne prone skin.
Gender:
ALL
Ages:
Between 18 years and 35 years
Trial Updated:
10/06/2023
Locations: Integrative Skin and Research, Sacramento, California
Conditions: Skin Microboime, Acne
Register for Updates
Imaging of T-cell Activation With [18F]F-AraG in Advanced Non Small Cell Lung Cancer
NCT04726215
Recruiting
This is a pilot study using \[18F\]F AraG PET imaging to evaluate the immunological response to checkpoint inhibitor therapy (CkIT) in patients with advanced NSCLC tumors at multiple study sites. The main objectives of the study are to quantify the change in \[18F\]F AraG PET signal before and after CkIT therapy, and to correlate this change in \[18F\]F AraG PET signal with a radiographic response.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
09/27/2023
Locations: Sutter Cancer Center, Sacramento, California
Conditions: Non Small Cell Lung Cancer
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Cannabis Consumption and Driving Impairment Assessment on a Closed Course
NCT06059677
Recruiting
In a true experiment, roughly 300 volunteer participants will smoke active cannabis, a corresponding placebo, or no substance at all (control). Next, participants will complete a drive test and then be observed by actual California Highway Patrol (CHP) officers who will attempt to classify participants as impaired or unimpaired. CHP Officers will evaluate participants in the context of driving (i.e., while following participants in an actual patrol car), as part of a roadside behavioral assessme... Read More
Gender:
ALL
Ages:
Between 21 years and 55 years
Trial Updated:
09/26/2023
Locations: California Department of Motor Vehicles Headquarters, Sacramento, California
Conditions: Cannabis Smoking, Driving Impaired
Register for Updates