There are currently 621 clinical trials in Sacramento, California looking for participants to engage in research studies. Trials are conducted at various facilities, including University of California Davis Comprehensive Cancer Center, University of California, Davis Medical Center, University of California, Davis and Sutter Medical Center Sacramento. Whether you're a healthy volunteer looking to participate in paid medical research or seeking trials related to a specific condition, the city provides a diverse range of opportunities near you.
Characterization of the Melanoma-Specific Immune Response
NCT00368615
Recruiting
The aim of this study is to study T-cells. Blood will be collected and the samples will be used to generate T cell clones. Two separate blood draws will be required at the maximum.
Gender:
All
Ages:
Between 18 years and 85 years
Trial Updated:
01/19/2024
Locations: University of California, Davis Department of Dermatology, Sacramento, California
Conditions: Melanoma
Register for Updates
Alternation in the Human Microbiome With Commonly Used Topical Medications
NCT03437005
Recruiting
The global aim of this study is to investigate how the human microbiome changes from baseline with commonly used topical medications such as topical antifungals, low to mid potency topical steroids and emollients. The specific aims are as follows: Investigate whether ketoconazole cream, a commonly used topical antifungal, causes alterations in the human skin microbiome with short-term use. Investigate whether desonide 0.05 % ointment, a commonly used low potency topical steroid, alters the hum... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
01/19/2024
Locations: University of California, Davis, Department of Dermatology, Sacramento, California
Conditions: Healthy
Register for Updates
Multi-center Trial in Adult and Pediatric Patients With Type 1 Diabetes Using Hybrid Closed Loop System and Control at Home
NCT02748018
Recruiting
The purpose of this study is to evaluate the safety and effectiveness of the Hybrid Closed Loop system (HCL) in adult and pediatric patients with type 1 diabetes in the home setting. A diverse population of patients with type 1 diabetes will be studied. The study population will have a large range for duration of diabetes and glycemic control, as measured by glycosylated hemoglobin (A1C). They will be enrolled in the study regardless of their prior diabetes regimen, including using Multiple Dail... Read More
Gender:
All
Ages:
Between 2 years and 80 years
Trial Updated:
01/18/2024
Locations: Center of Excellence in Diabetes & Endocrinology, Sacramento, California
Conditions: Type 1 Diabetes
Register for Updates
Niraparib Before Surgery in Treating Patients With High Risk Localized Prostate Cancer and DNA Damage Response Defects
NCT04030559
Recruiting
This phase II trial studies how well niraparib, when given before surgery, works in treating patients with high risk prostate cancer that has not spread to other parts of the body (localized) and alterations in deoxyribonucleic acid (DNA) repair pathways. Niraparib may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth.
Gender:
Male
Ages:
18 years and above
Trial Updated:
01/18/2024
Locations: University of California Davis Comprehensive Cancer Center, Sacramento, California
Conditions: ATM Gene Mutation, BRCA1 Gene Mutation, BRCA2 Gene Mutation, BRIP1 Gene Mutation, CDK12 Gene Mutation, CHEK1 Gene Mutation, CHEK2 Gene Mutation, DNA Damage Response Gene Mutation, DNA Repair Gene Mutation, FANCA Gene Mutation, FANCD2 Gene Mutation, FANCL Gene Mutation, GEN1 Gene Mutation, NBN Gene Mutation, Prostate Carcinoma, RAD51 Gene Mutation, RAD51C Gene Mutation
Register for Updates
Brentuximab Vedotin and Bendamustine for the Treatment of Relapsed or Refractory Follicular Lymphoma
NCT04587687
Recruiting
This phase II trial investigates how well brentuximab vedotin and bendamustine work in treating patients with follicular lymphoma that has come back (relapsed) or does not respond to treatment (refractory). Brentuximab vedotin is a monoclonal antibody, brentuximab, linked to a toxic agent called vedotin. Brentuximab attaches to CD30 positive cancer cells in a targeted way and delivers vedotin to kill them. Chemotherapy drugs, such as bendamustine, work in different ways to stop the growth of can... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
01/18/2024
Locations: University of California Davis Comprehensive Cancer Center, Sacramento, California
Conditions: Recurrent Follicular Lymphoma, Refractory Follicular Lymphoma
Register for Updates
Obinutuzumab, Ibrutinib, and Venetoclax for the Treatment of Previously Untreated Stage II-IV Follicular Lymphoma
NCT04450173
Recruiting
This phase II trial studies how well obinutuzumab, ibrutinib, and venetoclax work in treating patients with previously untreated stage II-IV follicular lymphoma. Immunotherapy with obinutuzumab may induce changes in body's immune system and may interfere with the ability of tumor cells to grow and spread. Ibrutinib and venetoclax may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth. Giving obinutuzumab, ibrutinib, and venetoclax together may work better in tr... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
01/18/2024
Locations: University of California Davis Comprehensive Cancer Center, Sacramento, California
Conditions: Ann Arbor Stage II Follicular Lymphoma, Ann Arbor Stage III Follicular Lymphoma, Ann Arbor Stage IV Follicular Lymphoma, Grade 1 Follicular Lymphoma, Grade 2 Follicular Lymphoma, Grade 3a Follicular Lymphoma
Register for Updates
First-in-human Study of the Theranostic Pair [68Ga]Ga DOTA-5G and [177Lu]Lu DOTA-ABM-5G in Pancreatic Cancer
NCT04665947
Recruiting
This is a Phase I, first-in-human study to evaluate the safety and efficacy of the [68Ga]Ga DOTA-5G and [177Lu]Lu DOTA-ABM-5G theranostic pair in patients with locally advanced or metastatic pancreatic adenocarcinoma (PDAC).
Gender:
All
Ages:
18 years and above
Trial Updated:
01/18/2024
Locations: University of California Davis, Sacramento, California
Conditions: Metastatic Pancreatic Cancer, Locally Advanced Pancreatic Adenocarcinoma
Register for Updates
The Rapid Diagnosis of MCI and Depression in Patients Ages 60 and Over
NCT06011681
Recruiting
Mild cognitive impairment (MCI) leading to Alzheimer's disease and related disorders (ADRD) represents a significant health and economic burden of the rapidly expanding senior population. The accurate detection and diagnosis of MCI and its common comorbidity, late-life depression (LLD), is essential for prolonging patient quality of life and developing advancements in research and treatment options. The purpose of the proposed program is to refine Miro Health's A.I. to accurately detect, differe... Read More
Gender:
All
Ages:
60 years and above
Trial Updated:
01/18/2024
Locations: Miro Health, Sacramento, California
Conditions: Depression, Mild Cognitive Impairment
Register for Updates
A Study Assessing Corneal Endothelial Cells in Patients With Neovascular Age-related Macular Degeneration Treated With the Port Delivery System With Ranibizumab (PDS)
NCT04853251
Recruiting
This study will assess corneal endothelial cells in patients with neovascular age-related macular degeneration (nAMD) treated with Port Delivery System with ranibizumab (PDS) refilled every 24 weeks (Q24W)
Gender:
All
Ages:
50 years and above
Trial Updated:
01/16/2024
Locations: Retinal Consultants Med Group, Sacramento, California
Conditions: Neovascular Age-related Macular Degeneration
Register for Updates
Clarifying the Optimal Application of SLT Therapy Trial
NCT04967989
Recruiting
The goal of this study is to understand if SLT performed at low energy is as effective as SLT performed at standard energy, and also to see if repeating SLT at low energy once a year will prevent or delay the need for daily eye drop medications better than waiting for SLT to wear off before repeating it.
Gender:
All
Ages:
18 years and above
Trial Updated:
01/14/2024
Locations: University of California, Davis, Sacramento, California
Conditions: Glaucoma and Ocular Hypertension
Register for Updates
A Study to Evaluate the Effect of SAGE-718 on Cognitive Function in Participants With Huntington's Disease (HD)
NCT05107128
Recruiting
The primary purpose of this study is to evaluate the effect of SAGE-718 on cognitive performance and functioning in participants with HD.
Gender:
All
Ages:
Between 25 years and 65 years
Trial Updated:
01/12/2024
Locations: Sage Investigational Site, Sacramento, California
Conditions: Huntington's Disease
Register for Updates
TRISCEND II Pivotal Trial
NCT04482062
Recruiting
Pivotal trial to evaluate the safety and effectiveness of the Edwards EVOQUE tricuspid valve replacement system
Gender:
All
Ages:
18 years and above
Trial Updated:
01/12/2024
Locations: UC Davis Medical Center, Sacramento, California
Conditions: Tricuspid Valve Regurgitation, Tricuspid Valve Insufficiency, Tricuspid Valve Disease, Heart Valve Diseases, Cardiovascular Diseases, Heart Failure
Register for Updates