There are currently 596 clinical trials in Sacramento, California looking for participants to engage in research studies. Trials are conducted at various facilities, including University of California Davis Comprehensive Cancer Center, University of California Davis Medical Center, University Of California Davis and Sutter Medical Center Sacramento. Whether you're a healthy volunteer looking to participate in paid medical research or seeking trials related to a specific condition, the city provides a diverse range of opportunities near you.
CoQ10 and Exercise for Mitochondrial Dysfunction in Advance Kidney Disease
NCT05422534
Recruiting
Frailty and sarcopenia are modifiable risk factors for morbidity and mortality in patients with ESRD. Exercise is the recommended intervention to prevent frailty and sarcopenia, however, many clinical trials have shown limited clinical improvement in muscle mass and physical function. We propose that mitochondrial dysfunction is one of the deterrents to the effectiveness of the exercise. We plan to evaluate the additive effect of HIIT and CoQ10, a mitochondrial-targeted therapy, on mitochondrial... Read More
Gender:
ALL
Ages:
Between 18 years and 75 years
Trial Updated:
10/23/2024
Locations: University of California Davis Health, Sacramento, California
Conditions: End Stage Renal Disease
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A Study of the Natural History of Participants With LGMD2E/R4, LGMD2D/R3, LGMD2C/R5, and LGMD2A/R1 ≥ 4 Years of Age, Who Are Managed in Routine Clinical Practice
NCT04475926
Recruiting
This study will follow participants who are screened and confirmed with a genetic diagnosis of Limb-girdle muscular dystrophy type 2E (LGMD2E/R4), Limb-girdle muscular dystrophy type 2D (LGMD2D/R3), Limb-girdle muscular dystrophy type 2C (LGMD2C/R5), or Limb-girdle muscular dystrophy type 2A (LGMD2A/R1). These enrolled participants will be followed to evaluate mobility and pulmonary function for up to 5 years after enrollment for participants with LGMD2C/R5, LGMD2D/R3, and LGMD2E/R4 with a Nort... Read More
Gender:
ALL
Ages:
4 years and above
Trial Updated:
10/16/2024
Locations: University of California, Davis Health Dept of PM&R, Sacramento, California
Conditions: Limb-girdle Muscular Dystrophy
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Performance and Safety of a Digital Tool for Unsupervised Self-assessment of NMOSD
NCT05566769
Recruiting
NMOSDCopilot is a digital tool developed for the self-assessment of Neuromyelitis Optica Spectrum Disorder symptoms that impact patients' functioning and quality of life. It has been co-designed with the help of patient advocacy groups, NMOSD patients and medical experts. It includes a smartphone-based application for patients, connected to a web portal developed for healthcare professionals (HCSPs). The patient application is composed of vision, walking, cognition, and dexterity e-active tests... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
10/14/2024
Locations: University of California Davis Health, Sacramento, California
Conditions: Neuromyelitis Optica
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Pivotal 2 Study of RGX-314 Gene Therapy in Participants With nAMD
NCT05407636
Recruiting
ABBV-RGX-314 (also known as RGX-314) is being developed as a novel one-time gene therapy for the treatment of neovascular (wet) age-related macular degeneration (wet AMD). Wet AMD is characterized by loss of vision due to new, leaky blood vessel formation in the retina. Wet AMD is a significant cause of vision loss in the United States, Europe and Japan, with up to 2 million people living with wet AMD in these geographies alone. Current anti-vascular endothelial growth factor (VEGF) therapies ha... Read More
Gender:
ALL
Ages:
Between 50 years and 89 years
Trial Updated:
10/14/2024
Locations: Retinal Consultants Medical Group, Inc, Sacramento, California +1 locations
Conditions: AMD, nAMD, Wet Age-related Macular Degeneration, wAMD, WetAMD, CNV
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Sacramento Clinical High Risk for Psychosis Stepped-Care Program
NCT06640803
Recruiting
This is a dissemination and implementation study that is evaluating a stepped-care intervention for identifying and treating youths at clinical high-risk for psychosis within multiple community mental health centers.
Gender:
ALL
Ages:
Between 12 years and 25 years
Trial Updated:
10/11/2024
Locations: University of California Department of Psychiatry and Behavioral Sciences; Early Psychosis Programs, Sacramento, California +3 locations
Conditions: Clinical High Risk for Psychosis, Ultra High Risk for Psychosis
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Macronutrients in Lactating NICU Parents - Impact of Kangaroo Care
NCT06047470
Recruiting
The goal of this clinical trial is to learn about the impact of Kangaroo Care (holding your baby skin-to-skin on your chest) in lactating parents with babies in the Neonatal Intensive Care Unit (NICU) that cannot directly breastfeed.
Gender:
FEMALE
Ages:
Between 18 years and 100 years
Trial Updated:
10/08/2024
Locations: UC Davis, Sacramento, California
Conditions: Lactation Disorder With Baby Delivered, Nutrition Disorder, Infant
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Add-on Reparixin in Adult Patients With ARDS
NCT05496868
Recruiting
Study objectives 1. To characterize the efficacy of reparixin in ameliorating lung injury and systemic inflammation and expediting clinical recovery and liberation from mechanical ventilation in adult patients with moderate to severe ARDS (PaO2/FIO2 ratio ≤ 200). 2. to assess the effect of reparixin on systemic biomarkers linked to a hyper-inflammatory ARDS phenotype. 3. To evaluate the safety of reparixin vs. placebo in patients enrolled in the study.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
10/03/2024
Locations: Unversity of California Davis Medical Center, Sacramento, California
Conditions: Acute Respiratory Distress Syndrome, Adult
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Access BNP Clinical Enrollment Study
NCT06624293
Recruiting
The goal of this study is to collect blood from subjects with a suspicion of either new onset or worsened heart failure to be used for testing studies for a new product to aid in the diagnosis of heart failure.
Gender:
ALL
Ages:
22 years and above
Trial Updated:
10/01/2024
Locations: UC Davis Health Department of Emergency Medicine, Sacramento, California
Conditions: Heart Failure
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An Open-Label ProSpective MultiCENTer Study to Evaluate Safety and Tolerability of Dry Powder Inhaled Treprostinil in PH
NCT06129240
Recruiting
Study LTI-401 is an open-label, multicenter study which will evaluate the safety and tolerability of LIQ861 in subjects who have WHO Group 1 \& 3 PH.
Gender:
ALL
Ages:
Between 18 years and 80 years
Trial Updated:
10/01/2024
Locations: UC Davis, Sacramento, California
Conditions: Pulmonary Hypertension, Interstitial Lung Disease
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Olorofim Aspergillus Infection Study
NCT05101187
Recruiting
The purpose of this study is to compare treatment with olorofim versus treatment with AmBisome® followed by standard of care (SOC) in patients with IFD caused by proven IA or probable lower respiratory tract disease Aspergillus species (invasive aspergillosis, IA).
Gender:
ALL
Ages:
18 years and above
Trial Updated:
09/26/2024
Locations: University of California Davis Health System, Sacramento, California
Conditions: Invasive Aspergillosis
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Cellular Therapy for In Utero Repair of Myelomeningocele - The CuRe Trial
NCT04652908
Recruiting
Spina bifida, or myelomeningocele (MMC), is a birth defect that results in paralysis, excess fluid on the brain (hydrocephalus), and impaired ability to urinate and have bowel movements normally. In a previous study (the MOMS trial), surgery before birth (in-utero/fetal surgery) was shown to reduce the need for shunting for hydrocephalus. There was also some improvement in ambulation, but 58 % of the children still could not walk unassisted. This study is testing living stem cells from placenta... Read More
Gender:
ALL
Ages:
Between 19 weeks and 25 weeks
Trial Updated:
09/26/2024
Locations: UC Davis Health, Sacramento, California
Conditions: Myelomeningocele
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Prospective Study of Nutraceutical Supplements to Support Hair Growth in Females
NCT06376409
Recruiting
A single site open label interventional study evaluating currently marketed hair supplements targeting the underlying root causes of thinning hair.
Gender:
FEMALE
Ages:
Between 18 years and 70 years
Trial Updated:
09/23/2024
Locations: Integrative Skin Science and Research, Sacramento, California
Conditions: Hair Thinning
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