There are currently 608 clinical trials in Sacramento, California looking for participants to engage in research studies. Trials are conducted at various facilities, including University of California Davis Comprehensive Cancer Center, University of California Davis Medical Center, University Of California Davis and Sutter Medical Center Sacramento. Whether you're a healthy volunteer looking to participate in paid medical research or seeking trials related to a specific condition, the city provides a diverse range of opportunities near you.
Brain Oxygen Optimization in Severe TBI, Phase 3
NCT03754114
Recruiting
BOOST3 is a randomized clinical trial to determine the comparative effectiveness of two strategies for monitoring and treating patients with traumatic brain injury (TBI) in the intensive care unit (ICU). The study will determine the safety and efficacy of a strategy guided by treatment goals based on both intracranial pressure (ICP) and brain tissue oxygen (PbtO2) as compared to a strategy guided by treatment goals based on ICP monitoring alone. Both of these alternative strategies are used in s... Read More
Gender:
ALL
Ages:
14 years and above
Trial Updated:
12/06/2024
Locations: UC Davis Medical Center, Sacramento, California
Conditions: Brain Injuries, Traumatic
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Post-Market Study to Assess iTind Safety in Comparison to UroLift
NCT04757116
Recruiting
The study objective is to evaluate the safety of the iTind device comparied to UroLift.
Gender:
MALE
Ages:
50 years and above
Trial Updated:
12/05/2024
Locations: Golden State Urology, Sacramento, California
Conditions: Benign Prostatic Hyperplasia (BPH)
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Exercise and Nutritional Prehabilitation for Head and Neck Cancer Patients
NCT06722508
Recruiting
This study examines the acceptability, feasibility, and safety in developing a prehabilitation program for head and neck cancer patients. The purpose of this research is to access the safety and acceptability of using a prehabilitation program before head and neck cancer surgery.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
12/05/2024
Locations: UC Davis Health, Sacramento, California +1 locations
Conditions: Head Cancer, Neck Cancer, Sarcopenia, Head and Neck Cancer
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Longitudinal Assessment of Brain Structure and Function in Juvenile-onset Huntington's Disease
NCT05707663
Recruiting
The goal of this observational study is to learn about brain development in Juvenile-onset Huntington's Disease (JoHD). The main questions it aims to answer are: * Is brain development different in JoHD than Adult-onset Huntington's Disease (AoHD)? * Can reliable biomarkers for JoHD be found in brain structure and function? Participants will be asked to complete cognitive tests, behavioral assessments, physical and neurologic evaluation, and MRI. Data collected will be compared to populations... Read More
Gender:
ALL
Ages:
Between 6 years and 30 years
Trial Updated:
12/04/2024
Locations: University of California Davis, Sacramento, California
Conditions: Juvenile Huntington Disease, Juvenile-Onset Huntington Disease
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Fetal Endoscopic Tracheal Occlusion for CDH (CDH)
NCT05421676
Recruiting
This is a single site pilot trial to assess the feasibility and safety of treating severe CDH with Fetal Endoscopic Tracheal Occlusion with the Goldballoon Detachable Balloon (GOLDBAL2) along with the Delivery Microcatheter (BALTACCI-BDPE100) at UC Davis Medical Center. The study will enroll pregnant women that meet study criteria. Participants will have placement of FETO between gestational age at 27 weeks plus 0 days and 29 weeks 6 days. The timing for removal of FETO will ideally be between 3... Read More
Gender:
FEMALE
Ages:
18 years and above
Trial Updated:
12/03/2024
Locations: UC Davis Medical Center, Sacramento, California
Conditions: Congenital Diaphragmatic Hernia
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Fluorine-18-AlphaVBeta6-Binding Peptide Positron Emission Tomography in Metastatic Non-Small Cell Lung Cancer
NCT05452005
Recruiting
This study investigates fluorine-18-AlphaVBeta6-BP (\[18F\]-αvβ6-BP) as a Positron Emission (PET) imaging agent in Non-Small Cell Lung Cancer (NSCLC) patients with brain metastases. Investigators hypothesize that \[18F\]-αvβ6-BP PET/Computed Tomography (CT) is a sensitive tool for disease assessment in patients with metastatic NSCLC, including those with brain metastases.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
12/03/2024
Locations: The University of California Davis Comprehensive Cancer Center, Sacramento, California
Conditions: Lung Cancer, Lung Cancer Metastatic, Brain Metastases, Non Small Cell Lung Cancer
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A Research Study of Abdominal Ultrasound (FAST) in Children With Blunt Torso Trauma
NCT05910567
Recruiting
Bleeding from intra-abdominal injuries is a leading cause of traumatic deaths in children. Abdominal CT is the reference standard test for diagnosing intra-abdominal injuries. Compelling reasons exist, however, to both aggressively evaluate injured children for intra-abdominal injuries with CT and to limit abdominal CT evaluation to solely those at non-negligible risk. The focused assessment sonography for trauma (FAST) examination can help focus patient evaluation in just this manner by potenti... Read More
Gender:
ALL
Ages:
17 years and below
Trial Updated:
12/03/2024
Locations: University of California, Davis Medical Center, Sacramento, California
Conditions: Blunt Trauma to Abdomen, Wounds and Injuries, Abdomen Injury, Abdominal Injury, Abdomen, Acute
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Sparking Gut Bacteria Production of Bioactive Xenolipids in Situ
NCT06313606
Recruiting
Long-chain cyclopropane fatty acids (CpFAs) are microbially-derived lipids (fats), some of which can be found in select foods and appear to be produced naturally in the gut from dietary fatty acid precursors. Some of these lipids appear to have signaling properties in the body's tissues, i.e., to help regulate cardiometabolic health. Thus, increasing the bioavailability of CpFAs in humans may have utility to improve management of blood sugar and blood lipids, or to mitigate or prevent non-alcoho... Read More
Gender:
ALL
Ages:
Between 18 years and 50 years
Trial Updated:
12/03/2024
Locations: University of California, Davis School of Medicine, Sacramento, California
Conditions: Dietary Fat Metabolism
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Molecularly Targeted Theranostic Approach for the Detection and Treatment of Metastatic Carcinomas
NCT06389123
Recruiting
This is a Phase I study to evaluate the safety and efficacy of the \[68Ga\]Ga DOTA-5G and \[177Lu\]Lu DOTA-ABM-5G theranostics pair in patients with metastatic cancer.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
12/03/2024
Locations: The University of California Davis Comprehensive Cancer Center, Sacramento, California
Conditions: Metastatic Cancer
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Feasibility of the BrainGate2 Neural Interface System in Persons With Tetraplegia (BG-Speech-02)
NCT06094205
Recruiting
The goal of this study is to improve our understanding of speech production, and to translate this into medical devices called intracortical brain-computer interfaces (iBCIs) that will enable people who have lost the ability to speak fluently to communicate via a computer just by trying to speak.
Gender:
ALL
Ages:
Between 18 years and 80 years
Trial Updated:
11/27/2024
Locations: University of California, Davis, Sacramento, California
Conditions: Anarthria, Dysarthria, Tetraplegia, Spinal Cord Injuries, Amyotrophic Lateral Sclerosis, Brain Stem Infarctions, Locked-in Syndrome, Muscular Dystrophies
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Immunologic Response to Pneumococcal Polysaccharide Vaccine in Splenic Injury Patients
NCT02232191
Recruiting
Persons without a spleen are susceptible to potentially lethal infections from certain bacteria, with pneumococcus being the most prevalent. Vaccines are provided to help protect against these infections, though they do not so with certainty. Trauma patients who sustain an injury to their spleen currently have three treatment options available for the treating surgeon - nonoperative management, embolization, or removal of the spleen. The purpose of this study is to investigate the antibody respo... Read More
Gender:
ALL
Ages:
Between 18 years and 65 years
Trial Updated:
11/26/2024
Locations: University of California, Davis Medical Center, Sacramento, California
Conditions: Asplenia
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A Study of MACI in Patients Aged 10 to 17 Years With Symptomatic Chondral or Osteochondral Defects of the Knee
NCT03588975
Recruiting
The objective of this study is to compare the efficacy and safety of MACI® vs arthroscopic microfracture in the treatment of patients aged 10 to 17 years with symptomatic articular chondral or osteochondral defects of the knee.
Gender:
ALL
Ages:
Between 10 years and 17 years
Trial Updated:
11/26/2024
Locations: Shriner's Hospital for Children Northern California, Sacramento, California +1 locations
Conditions: Chondral Defect, Articular Cartilage Defect, Articular Cartilage Disorder of Knee, Osteochondritis Dissecans (OCD)
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