There are currently 621 clinical trials in Sacramento, California looking for participants to engage in research studies. Trials are conducted at various facilities, including University of California Davis Comprehensive Cancer Center, University of California, Davis Medical Center, University of California, Davis and Sutter Medical Center Sacramento. Whether you're a healthy volunteer looking to participate in paid medical research or seeking trials related to a specific condition, the city provides a diverse range of opportunities near you.
Pain and Quality of Life After Retromuscular Ventral Hernia Repair (RECOVER)
NCT04487522
Recruiting
The study aims to explore the difference in outcomes relating to pain and quality of life after open, laparoscopic, and robotic-assisted retromuscular ventral hernia repair.
Gender:
All
Ages:
Between 18 years and 89 years
Trial Updated:
09/26/2023
Locations: Kaiser Foundation Research Institute, South Sacramento, Sacramento, California
Conditions: Ventral Hernia
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Cellular Therapy for In Utero Repair of Myelomeningocele - The CuRe Trial
NCT04652908
Recruiting
Spina bifida, or myelomeningocele (MMC), is a disorder where the lower part of the spinal cord of the fetus is exposed, meaning there is no bone or skin covering it. This is dangerous because the spinal cord contains cells which control one's ability to move their legs and walk, and also to be able to urinate and have bowel movements normally. One of the current treatments for fetal MMC is to perform a surgery on the fetus before it is born which has many names including in utero surgery, prenat... Read More
Gender:
All
Ages:
Between 19 weeks and 25 weeks
Trial Updated:
09/26/2023
Locations: UC Davis Health, Sacramento, California
Conditions: Myelomeningocele
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Cannabis Consumption and Driving Impairment Assessment on a Closed Course
NCT06059677
Recruiting
In a true experiment, roughly 300 volunteer participants will smoke active cannabis, a corresponding placebo, or no substance at all (control). Next, participants will complete a drive test and then be observed by actual California Highway Patrol (CHP) officers who will attempt to classify participants as impaired or unimpaired. CHP Officers will evaluate participants in the context of driving (i.e., while following participants in an actual patrol car), as part of a roadside behavioral assessme... Read More
Gender:
All
Ages:
Between 21 years and 55 years
Trial Updated:
09/26/2023
Locations: California Department of Motor Vehicles Headquarters, Sacramento, California
Conditions: Cannabis Smoking, Driving Impaired
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Neonatal Pulse Oximetry Disparities Due to Skin Pigmentation
NCT06063148
Recruiting
The goal of this clinical trial is to determine if pulse oximeters show an SaO2-SpO2 discrepancy that correlates with skin pigmentation such that pulse oximetry will overestimate oxygenation in newborns with darker skin. The main questions it aims to answer is if SaO2-SpO2 discrepancy varies with the degree of skin pigmentation among neonates, if gestational age has an influence on SaO2-SpO2 discrepancy, and if packed red blood cell (PRBC) transfusion has an influence on SaO2-SpO2 discrepancy in... Read More
Gender:
All
Ages:
10 days and below
Trial Updated:
09/25/2023
Locations: UC Davis Health, Sacramento, California
Conditions: Skin Pigment, Pulse Oximetry
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Uproleselan, Azacitidine, and Venetoclax for the Treatment of Treatment Naive Acute Myeloid Leukemia
NCT04964505
Recruiting
This phase I trial evaluates the side effects of uproleselan, azacitidine, and venetoclax in treating older or unfit patients with treatment naive acute myeloid leukemia. Uproleselan may help block the formation of growths that may become cancer. Chemotherapy drugs, such as azacitidine, work in different ways to stop the growth of cancer cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading. Venetoclax may stop the growth of cancer cells by blocki... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
09/25/2023
Locations: University of California Davis Comprehensive Cancer Center, Sacramento, California
Conditions: Acute Myeloid Leukemia
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A Study of ELAPRASE in Treatment-naïve Participants With Hunter Syndrome (Mucopolysaccharidosis [MPS] II)
NCT05494593
Recruiting
The main aim of this study is to evaluate the ability of a prophylactic immune tolerizing regimen (ITR) to prevent or reduce the development of high titer anti-idursulfase antibodies in treatment-naïve participants with Hunter syndrome. In this open label, single arm study, all participants will receive ELAPRASE treatment and a prophylactic ITR. Participants will be treated with ELAPRASE for up to 104 weeks. The prophylactic ITR will start 1 day prior to the start of ELAPRASE. The prophylactic... Read More
Gender:
Male
Ages:
6 years and below
Trial Updated:
09/21/2023
Locations: UC Davis Medical Center, Sacramento, California
Conditions: Mucopolysaccharidosis (MPS), Hunter Syndrome
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The Efficacy and Safety of TLL018 in Moderate-to-severe Plaque Psoriasis
NCT05772520
Recruiting
This is a Phase 2, multicenter, randomized, double-blinded, parallel dose group, placebo-controlled, dose-ranging study to evaluate the efficacy and safety of 3 doses of TLL018 as therapy in 120 participants with moderate-to-severe PP.
Gender:
All
Ages:
Between 18 years and 75 years
Trial Updated:
09/20/2023
Locations: Integrative Skin, Sacramento, California
Conditions: Plaque Psoriasis
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Intra-sheath vs Extra-sheath Injection for De Quervain's Tenosynovitis
NCT04895956
Recruiting
The aim of the study is to determine whether or not extra-sheath steroid injections are inferior to intra-sheath steroid injections in the treatment of DeQuervain's Tenosynovitis. Patients will be randomized to either the intra-sheath group or the extra-sheath group and their pre-injection level of pain will be assessed using the visual analog scale. Appropriate injections will then be administered by 1 of 3 UC Davis hand surgeons. Six weeks post injection the patients will be reassessed using... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
09/13/2023
Locations: UC Davis Health, Department of Orthopaedics, Sacramento, California
Conditions: De Quervain Tenosynovitis
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Green Sun Medical Dynamic Scoliosis Brace
NCT03641469
Recruiting
This is a pilot study to collect preliminary short-term data concerning the safety and performance of the Green Sun Dynamic brace in a sample of subjects with adolescent idiopathic scoliosis who are currently being treated with a TLSO.
Gender:
Female
Ages:
Between 10 years and 15 years
Trial Updated:
09/12/2023
Locations: Shriners Hospitals for Children - Northern California, Sacramento, California
Conditions: Adolescent Idiopathic Scoliosis
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Ascending Glycan Dietary Supplementation in Healthy Adults
NCT04466761
Recruiting
The investigators will conduct a parallel-group, placebo-controlled, randomized, double-blind ascending dose Phase I study of dietary supplementation in healthy individuals to evaluate safety and to determine the pharmacologically effective dose (ED).
Gender:
All
Ages:
Between 18 years and 45 years
Trial Updated:
09/12/2023
Locations: University of California, Davis Medical Center, Sacramento, California
Conditions: Healthy Individuals
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Autologous Adipose-derived Stromal Vascular Fraction for Treatment of Knee Osteoarthritis
NCT04440189
Recruiting
This study is a pivotal study to evaluate the efficacy and safety of a single injection of autologous adipose-derived SVF produced using the GID SVF-2 device system for treatment of pain with concomitant improvement in function associated with osteoarthritis of the knee joint.
Gender:
All
Ages:
Between 35 years and 85 years
Trial Updated:
09/07/2023
Locations: UC Davis, Sacramento, California
Conditions: Osteoarthritis, Knee
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Study of Kidney Tumors in Younger Patients
NCT00898365
Recruiting
This research trial studies kidney tumors in younger patients. Collecting and storing samples of tumor tissue, blood, and urine from patients with cancer to study in the laboratory may help doctors learn more about changes that occur in deoxyribonucleic acid (DNA) and identify biomarkers related to cancer.
Gender:
All
Ages:
29 years and below
Trial Updated:
09/06/2023
Locations: Sutter Medical Center Sacramento, Sacramento, California +1 locations
Conditions: Adult Cystic Nephroma, Anaplastic Kidney Wilms Tumor, Angiolipoma, Cellular Congenital Mesoblastic Nephroma, Classic Congenital Mesoblastic Nephroma, Clear Cell Sarcoma of the Kidney, Congenital Mesoblastic Nephroma, Cystic Partially Differentiated Kidney Nephroblastoma, Diffuse Hyperplastic Perilobar Nephroblastomatosis, Extrarenal Rhabdoid Tumor, Kidney Medullary Carcinoma, Kidney Neoplasm, Kidney Oncocytoma, Kidney Wilms Tumor, Metanephric Adenofibroma, Metanephric Adenoma, Metanephric Stromal Tumor, Metanephric Tumor, Mixed Congenital Mesoblastic Nephroma, Ossifying Renal Tumor of Infancy, Papillary Renal Cell Carcinoma, Renal Cell Carcinoma, Renal Cell Carcinoma Associated With Xp11.2 Translocations/TFE3 Gene Fusions, Rhabdoid Tumor of the Kidney, Wilms Tumor
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