There are currently 634 clinical trials in Sacramento, California looking for participants to engage in research studies. Trials are conducted at various facilities, including University of California Davis Comprehensive Cancer Center, University of California, Davis Medical Center, University of California, Davis and Sutter Medical Center Sacramento. Whether you're a healthy volunteer looking to participate in paid medical research or seeking trials related to a specific condition, the city provides a diverse range of opportunities near you.
Evaluating Treatment of ADHD in Children With Down Syndrome
NCT04219280
Recruiting
Children with Down syndrome (DS) have a 3-5 time greater prevalence of Attention Deficit Hyperactivity Disorder (ADHD) than typically developing (TD) children. Despite this higher risk of ADHD, rates of stimulant medication treatment are disproportionately low in children with DS+ADHD, even though stimulants are the most efficacious ADHD treatment and are recommended by consensus guidelines for use in children with intellectual disability and ADHD. The investigators propose the first randomized... Read More
Gender:
All
Ages:
Between 6 years and 17 years
Trial Updated:
06/02/2023
Locations: University of California Davis MIND Institute, Sacramento, California
Conditions: Down Syndrome, ADHD
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Utilization of Negative Pressure Suction to Reduce Aspiration in Oropharyngeal Dysphagia
NCT03368079
Recruiting
This is an investigator initiated prospective study to determine whether the use of a negative pressure suction in the hypopharynx will reduce the amount of aspiration during Video Fluoroscopic Swallowing Exam (VFSE) among patients with oropharyngeal dysphagia.
Gender:
All
Ages:
18 years and above
Trial Updated:
05/30/2023
Locations: UC Davis Medical Center, Sacramento, California
Conditions: Oropharyngeal Dysphagia
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Practical Approaches to Care in Emergency Syncope
NCT04533425
Recruiting
Syncope, or transient loss of consciousness, is a common reason for visit to the Emergency Department and often leads to extensive testing and hospitalization. Using objective risk scores to determine which patients with syncope will actually benefit from these interventions, and which can be safely discharged home with minimal testing, is critical to providing sensible medical care. This study will evaluate the validity of two syncope risk-stratification tools and investigate their impact on he... Read More
Gender:
All
Ages:
40 years and above
Trial Updated:
05/30/2023
Locations: UC Davis, Sacramento, California
Conditions: Syncope, Presyncope
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CAR-T Cells for HIV Infection
NCT04648046
Recruiting
This is a limited-center, open-label dose escalating phase I/IIa study of autologous T cells expressing LVgp120duoCAR molecules in people with HIV infection. It will follow a 3+3 design. Dose escalation decisions will be made when a minimum of three participants have completed the safety-evaluation period (45 days) at a given dose level. Cohort 1 will undergo infusion of a single low-dose regimen of LVgp120duoCAR-T cells. Cohort 2 will undergo non-ablative conditioning with cyclophosphamide, fol... Read More
Gender:
All
Ages:
Between 18 years and 65 years
Trial Updated:
05/26/2023
Locations: University of California, Davis, Sacramento, California
Conditions: HIV Infections
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Abbott DBS Post-Market Study of Outcomes for Indications Over Time
NCT04071847
Recruiting
The purpose of this international study is to evaluate long-term safety and effectiveness of Abbott deep brain stimulation (DBS) systems for all indications, including Parkinson's disease, essential tremor or other disabling tremor and dystonia.
Gender:
All
Ages:
All
Trial Updated:
05/26/2023
Locations: University of California at Davis, Sacramento, California
Conditions: Movement Disorders, Parkinson Disease, Essential Tremor, Tremor, Dystonia, Primary Dystonia, Secondary Dystonia
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Exercise Study Testing Enhanced Energetics of Mitochondria Video Integrated Delivery of Activity Training in CKD
NCT02923063
Recruiting
Skeletal muscle dysfunction (sarcopenia) is an under-recognized target organ complication of CKD with substantial adverse clinical consequences of disability, hospitalization, and death. Sarcopenia in this proposal is defined by impaired metabolism and physical function associated with decreased skeletal muscle mass or function. Skeletal muscle tissue relies on mitochondria to efficiently utilize oxygen to generate ATP. Impaired mitochondrial energetics is a central mechanism of sarcopenia in CK... Read More
Gender:
All
Ages:
Between 30 years and 75 years
Trial Updated:
05/22/2023
Locations: UC Davis Health, Sacramento, California
Conditions: Moderate-severe Chronic Kidney Disease Not Treated With Dialysis, Diabetic Kidney Disease, HgbA1c Less Than 8.5
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Pilot Trial of Eltrombopag in Patients Undergoing Chemotherapy for Malignant Solid Tumors
NCT04485416
Recruiting
Primary Objective: To assess safety of eltrombopag in pediatric patients undergoing intensive chemotherapy for malignant solid tumors. Secondary Objectives: To assess the efficacy of eltrombopag in increasing platelet count up to 2 weeks after completion of chemotherapy in pediatric patients undergoing intensive chemotherapy for malignant solid tumors. Hypothesis: The hypothesis is that eltrombopag an oral thrombopoietin receptor agonist will increase the platelet count safely and efficaciousl... Read More
Gender:
All
Ages:
Between 1 year and 18 years
Trial Updated:
05/20/2023
Locations: University of California Davis Health System, Comprehensive Cancer Center, Sacramento, California
Conditions: Solid Tumor, Childhood, Solid Tumor
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Comparing Combinations of Targeted Drugs for Advanced Non-Small Cell Lung Cancer That Has EGFR and MET Gene Changes (A Lung-MAP Treatment Trial)
NCT05642572
Recruiting
This phase II Lung-MAP treatment trial test the combination of targeted drugs (capmatinib, osimertinib, and/or ramucirumab) in treating patients with non-small cell lung cancer that may have spread from where it first started to nearby tissue, lymph nodes, or distant parts of the body (advanced) and that has EGFR and MET gene changes. Capmatinib and osimertinib are in a class of medications called kinase inhibitors. They work by blocking the action of the abnormal protein that signals cancer cel... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
05/19/2023
Locations: Mercy Cancer Center - Sacramento, Sacramento, California
Conditions: Recurrent Lung Non-Small Cell Carcinoma, Stage IV Lung Cancer AJCC v8
Register for Updates
PrecISE (Precision Interventions for Severe and/or Exacerbation-Prone Asthma) Network Study
NCT04129931
Recruiting
The primary objective of this study is to evaluate several interventions given to participants with severe asthma. Interventions are administered in a crossover manner with 16-week treatment periods followed by 8 to 16 week washout.
Gender:
All
Ages:
12 years and above
Trial Updated:
05/16/2023
Locations: University of California Davis, Sacramento, California
Conditions: Asthma
Register for Updates
National Collaborative to Improve Care of Children With Complex Congenital Heart Disease
NCT02852031
Recruiting
The purpose of this initiative is to improve care and outcomes for infants with HLHS by expanding the NPC-QIC national registry to gather clinical care process, outcome, and developmental data on infants with HLHS between diagnosis and 12 months of age, by improving the use of standards into everyday practice across pediatric cardiology centers, and by engaging parents as partners in the process.
Gender:
All
Ages:
15 months and below
Trial Updated:
05/15/2023
Locations: Sutter Medical Center-Sacramento, Sacramento, California +1 locations
Conditions: Hypoplastic Left Heart Syndrome (HLHS)
Register for Updates
HeartShare: Combining Omics, Deep Phenotyping, and Electronic Health Records for Heart Failure Subtypes and Treatment Targets
NCT05873634
Recruiting
HeartShare is a comprehensive study of heart failure, a common and serious medical condition which occurs when the heart is unable to keep up with the demands of the body, resulting in shortness of breath, fluid retention, and fatigue. HeartShare aims to better classify heart failure into subtypes to help develop more personalized treatments for patients, with the hope that this will improve the lives of heart failure patients. To do this, HeartShare is bringing together a large amount of data (... Read More
Gender:
All
Ages:
30 years and above
Trial Updated:
05/15/2023
Locations: University of California Davis, Sacramento, California
Conditions: Heart Failure, Heart Failure With Preserved Ejection Fraction
Register for Updates
Brain Boosters 2 in Persons at Risk for Alzheimer's Disease: a Digital Application Supported Intervention
NCT05027789
Recruiting
The purpose of this research is to determine if training in memory support aids and healthy lifestyle activities (physical exercise, mentally stimulating activities and stress management) can have a positive effect on memory, thinking, and activities that people do every day. Participation in this study will involve being placed into one of two groups: a Self-Guided Intervention Group or a Structured Intervention Group. Both groups will be asked to attend group sessions in which they will be pro... Read More
Gender:
All
Ages:
Between 65 years and 90 years
Trial Updated:
05/10/2023
Locations: University of California, Davis Alzheimer's Disease Center, Sacramento, California
Conditions: Memory Disorders, Cognitive Impairment
Register for Updates