San Diego, CA Clinical Trials

A listing of San Diego, CA clinical trials actively recruiting patient volunteers.

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833 trials found

A Phase 1 Dose Escalation Study of TDM-105795 Topical Solution in Male Subjects With Androgenetic Alopecia (AGA)

NCT04913519

Multi-center, fixed volume, randomized, double-blind, vehicle-controlled, parallel group, dose escalation comparison study of TDM-105795 in male subjects, 18 to 55 years old, with Androgenetic Alopecia (AGA).

Conditions: Alopecia, Androgenetic

To Evaluate the Safety and Efficacy of TQ Formula in Covid-19 Participants

NCT04914377

This is a randomized (1:1), double-blind, placebo-controlled phase 2 study to assess safety and efficacy of Total 3 g daily dose of Black Seed Oil (TQ Formula) capsules versus placebo in treating patients who have tested positive for novel Coronavirus 2019 (Covid-19) in the outpatient setting. Patients will be treated at a dose of 500 mg, 3 capsules, two times a day for 14 days from date of randomization. Quantitative viral load as measured by RT-PCR will be evaluated at baseline and on days 7 ...

Conditions: Covid19

A Clinical Trial to Evaluate the Safety, Tolerability, and Efficacy of Subjects With Plaque Psoriasis

NCT04908514

A Multi-Center, Open-Label, Phase 2 Clinical Trial to Evaluate the Safety, Tolerability, and Efficacy of ADX-629 Administered Orally to Subjects with Plaque Psoriasis

Conditions: Plaque Psoriasis

Child and Adolescent Registry for Participants With Narcolepsy

NCT04899947

The Registry will descriptively document the natural history and outcomes of patients with pediatric narcolepsy. Descriptive statistics on disease characteristics will be performed.

Conditions: Narcolepsy

MIS-C Comparative Effectiveness Study

NCT04898231

In March 2020, children exposed to the virus that causes the COVID-19 illness, SARS-CoV-2, presented with fever and significant inflammation about a month after exposure to the virus. Some children were sick enough to require care in the intensive care unit for what came to be known as Multisystem Inflammatory Syndrome-Children (MIS-C).The clinical presentation shared many features with Kawasaki disease (KD), a self-limited inflammation that can cause ballooning of the arteries of the heart. Thu ...

Conditions: Multisystem Inflammatory Syndrome-Children
Phase: Phase 2/3

Study of Safety and Tolerability of EO2002 in the Treatment of Corneal Edema

NCT04894110

Corneal edema is the most common indication for corneal transplantation, accounting for approximately 70% of penetrating keratoplasty (PK), and 100% of endothelial keratoplasty (EK) procedures annually. There is currently no disease-modifying treatment for corneal edema. Topical treatments like hypertonic saline are not effective on a long-term basis. For those with advanced disease, where edema and vision loss are not controlled by topical treatment, the only option is a corneal transplant. A p ...

Conditions: Corneal Edema, Corneal Endothelial Dysfunction, Corneal Endothelial Dystrophy, Fuchs Dystrophy, Fuchs Endothelial Corneal Dystrophy, Pseudophakic Bullous Keratopathy, Bullous Keratopathy, Endothelial Dysfunction, Moderate Corneal Endothelial Decompensation

APIOC for Presbyopia and APIOC for Presbyopia With Astigmatism

NCT04883099

Vision and comfort, both objective and subjective, will be assessed for single vision contact lens wearers for either the APIOC™ for Presbyopia or the APIOC™ for Presbyopia Astigmatism contact lenses.

Conditions: Presbyopia, Myopia, Hyperopia, Astigmatism
Phase: Not Applicable

A Study of Guselkumab in Participants With Active Psoriatic Arthritis

NCT04882098

The purpose of this study is to evaluate the efficacy of guselkumab treatment in participants with active psoriatic arthritis (PsA) by assessing the reduction in signs and symptoms of PsA.

Conditions: Arthritis, Psoriatic

Chronic Pain Master Protocol (CPMP): A Study of LY3556050 in Participants With Chronic Low Back Pain

NCT04874636

This study is being done to test the safety and efficacy of the study drug LY3556050 for the treatment of chronic low back pain. This trial is part of the chronic pain master protocol (H0P-MC-CPMP) which is a protocol to accelerate the development of new treatments for chronic pain.

Conditions: Chronic Low-back Pain

A Study of LY3437943 in Participants With Type 2 Diabetes

NCT04867785

The main purpose of this study is to evaluate the efficacy and safety of LY3437943 in participants with type 2 diabetes (T2D) who failed to achieve adequate glycemic control on diet and exercise alone or on a stable dose of metformin. This study will last about 43 weeks.

Conditions: Type 2 Diabetes

Memantine Augmentation of Targeted Cognitive Training in Schizophrenia

NCT04857983

Treatment of schizophrenia currently includes antipsychotic medications and cognitive therapies which improve some symptoms, but do not sufficiently restore cognitive functioning or reduce psychosocial disability. We hypothesize that medications that specifically target sensory information processing deficits, rather than psychotic symptoms per se, will significantly enhance the benefits of a sensory-based targeted cognitive training (TCT) intervention in patients with schizophrenia. We will com ...

Conditions: Schizophrenia, Schizoaffective Disorder
Phase: Phase 2/3

Placebo-Controlled Study of ADP101 for Oral Immunotherapy in Food-Allergic Children and Adults

NCT04856865

The purpose of this study is to assess the efficacy and safety of ADP101 in food allergic children and adults.

Conditions: Food Allergy
Phase: Phase 1/2