There are currently 734 clinical trials in San Diego, California looking for participants to engage in research studies. Trials are conducted at various facilities, including University of California, San Diego, Rady Children's Hospital San Diego, GSK Investigational Site and Naval Medical Center San Diego. Whether you're a healthy volunteer looking to participate in paid medical research or seeking trials related to a specific condition, the city provides a diverse range of opportunities near you.
Assessment of Urinary Polymerase Chain Reaction (PCR) and Next Generation Sequencing (NGS) Technology in the Evaluation and Management of Females With Chronic Bladder Pain and Cystitis-like Symptoms
Recruiting
Real-world clinical practice multicenter study to determine the clinical implications of employing PCR/NGS technology to identify and treat potential urinary pathogens in female participants identified with bladder pain and/or cystitis-like symptoms.
Gender:
Female
Ages:
Between 18 years and 80 years
Trial Updated:
03/13/2023
Locations: The University of California San Diego Health, San Diego, California
Conditions: Interstitial Cystitis, Bladder Pain Syndrome
Low-Dose Intravenous Ketamine for Adolescents With Depression and Suicidal Ideation in the Emergency Department
Recruiting
The goal of this study is to test whether a single low-dose of IV ketamine given in the emergency department to adolescents with treatment-resistant depression and suicidal ideation can reduce depression symptoms and suicidal thoughts compared to placebo. Participants will complete depression scales at baseline, and 1 hour, 3 hours, 1 day, 3 days, and 7 days after receiving the treatment.
Gender:
All
Ages:
Between 12 years and 18 years
Trial Updated:
02/15/2023
Locations: Rady Children's Hospital San Diego, San Diego, California
Conditions: Depression, Suicidal Ideation
Study of the Safety and Efficacy of STI-6643 in Subjects With Advanced Solid Tumors
Recruiting
This is a first-in-human, phase 1, open-label, dose-escalation study of STI-6643 administered by intravenous infusion in subjects with a relapsed/refractory advanced solid tumor.
Gender:
All
Ages:
18 years and above
Trial Updated:
01/12/2023
Locations: University of California, San Diego, San Diego, California
Conditions: Solid Tumor, Relapsed Solid Neoplasm, Refractory Tumor
Mobile Biosensor for Measuring Vital Signs in Healthcare and Home Settings
Recruiting
This study will record vital signs (heart rate and blood oxygen levels) using a new cell phone integrated biosensor and compare it to routine measurements carried out in the clinics and hospital at UCSD. Cell phones will be given to a selected group of subjects for use at home and data collected.
Gender:
All
Ages:
13 years and above
Trial Updated:
12/21/2022
Locations: UCSD AntiViral Research Center, San Diego, California
Conditions: Pulse Oximetry
Yersinia Pestis Lateral Flow Immunoassay for Blood Samples
Recruiting
Plague is a deadly but highly treatable disease caused by the bacterium Y. pestis. Due to the historical development of Y. pestis as a bioweapon by several nation states, it is listed by the US as a potential bioweapon that could be used against US warfighters. Although this bacterium is ecologically established worldwide, it mostly affects impoverished people who live in rural low-resource areas of Madagascar. Plague is acquired directly from bites of infected fleas but, if left untreated, it c... Read More
Gender:
All
Ages:
Between 5 years and 75 years
Trial Updated:
12/12/2022
Locations: US Naval Health Research Center, San Diego, California
Conditions: Plague, Plague, Bubonic, Plague, Pneumonic, Yersinia Pestis Plague, Yersinia Pestis; Bubo, Yersinia Pestis; Pneumonia, Yersinia Sepsis, Yersinia Pestis Infection, Bubo; Yersinia Pestis, Bubonic; Plague, Skin, Pneumonic Plague
Rady Children's Institute Genomic Biorepository
Recruiting
Rady Children's Institute for Genomic Medicine (RCI) will collect biological samples (such as blood), derived genomic sequences (from DNA and RNA), and clinical features in a Biorepository as a standardized resource for future research studies. The purpose of the Genomic Institute Biorepository is to provide consented samples and data for basic and clinical research related to the genomic cause and treatment of childhood disease, and, in the future, as reference (Quality Control) data to improve... Read More
Gender:
ALL
Ages:
All
Trial Updated:
12/08/2022
Locations: Rady Pediatric Genomics & Systems Medicine Institute, San Diego, California
Conditions: Genetic Diseases
Pediatric Cervical Spine Clearance: A Multicenter Prospective Observational Study
Recruiting
A prospective multicenter observational study, led by Dr. Katie Russell of Intermountain Primary Children's Hospital, that will examine the sensitivity, specificity, negative, and positive predictive values of CT scan and plain films in diagnosing cervical spine injury that requires treatment. This study is funded by the Primary Children's Hospital foundation.
Gender:
All
Ages:
Between 0 years and 17 years
Trial Updated:
11/01/2022
Locations: Rady Children's Hospital, San Diego, California
Conditions: Cervical Spine Fracture
Evaluation of The Comfort of Orthokeratology Lenses Fit Using A New Software
Recruiting
As new orthokeratology fitting software emerges onto the market, it is of interest to assess their usefulness in guiding eye practitioners with lens fit. The goal of this study is to evaluate the comfort of Paragon orthokeratology lenses when they are fit using the new Procornea software.
Gender:
All
Ages:
Between 6 years and 35 years
Trial Updated:
09/22/2022
Locations: 4S Eyecare and Optometry, San Diego, California
Conditions: Myopia
Safety, Tolerability, and Efficacy of AXA1125 in NASH With Fibrosis
Recruiting
This study will compare the effects of AXA1125, an orally active mixture of amino acids, compared to placebo, on improving fat and inflammation (steatohepatitis) as well as fibrosis in subjects with non alcoholic steatohepatitis (NASH). as well as the safety and tolerability of AXA1125. Subjects will take one of two different doses of AXA1125 or a placebo twice daily, and a liver biopsy will be done at the beginning and end of the 48-week study.
Gender:
All
Ages:
18 years and above
Trial Updated:
09/07/2022
Locations: Precision Research Institute, LLC, San Diego, California
Conditions: Non Alcoholic Steatohepatitis (NASH)
Diagnostic Accuracy and Safety of DBV1605 for the Diagnosis of Non-IgE Mediated Cow's Milk Allergy in Children
Recruiting
Study to assess the diagnostic accuracy (sensitivity, specificity, positive and negative predictive value) of DBV1605 for the diagnosis of non-Immunoglobulin E (IgE) mediated cow's milk allergy (CMA) in children with symptoms suggestive of non-IgE mediated CMA.
Gender:
All
Ages:
Between 29 days and 24 months
Trial Updated:
08/09/2022
Locations: University of California, Rady Children's Hospital, San Diego, California
Conditions: Cow's Milk Allergy
Erector Spinae Plane Block Catheters and Intrathecal Morphine for Hepatic Resection
Recruiting
To determine whether the addition of erector spinae plane (ESP) catheters to existing multimodal analgesic regimen with intrathecal morphine provides superior postoperative analgesia in patients undergoing hepatic resection compared with patients not receiving ESP catheters.
Gender:
All
Ages:
18 years and above
Trial Updated:
06/06/2022
Locations: University of California, San Diego, San Diego, California
Conditions: Hepatic Resection, Acute Pain, Anesthesia, Anesthesia, Local
International REgistry of COnservative or Radical Treatment of Localized Kidney Tumors
Recruiting
Partial nephrectomy (PN) is the standard treatment for localized renal masses and should be preferred in clinical T1 (<7 cm tumor diameter) renal tumors over radical nephrectomy (RN) whenever technically feasible. Nonetheless, indications, approaches, techniques for PN, and correct reporting of outcomes, are still a matter of great debate within the urology community. Concurrently, case-report series suggested that alternative strategies for the treatment of localized renal tumors (ablation tech... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
05/02/2022
Locations: University of California San Diego, Moores Cancer Center, San Diego, California
Conditions: Kidney Cancer