There are currently 707 clinical trials in San Diego, California looking for participants to engage in research studies. Trials are conducted at various facilities, including University of California, San Diego, Rady Children's Hospital - San Diego, GSK Investigational Site and Naval Medical Center - San Diego. Whether you're a healthy volunteer looking to participate in paid medical research or seeking trials related to a specific condition, the city provides a diverse range of opportunities near you.
Mechanistic and Clinical Outcomes of a Surgical Innovation Aimed at Minimizing GERD Associated With VSG (INNOVATE-VSG)
NCT06783751
Recruiting
This is a two-site randomized clinical trial aiming to test whether a modified investigational bariatric surgical procedure can improve gastroesophageal reflux disease (GERD) after sleeve gastrectomy.
Gender:
ALL
Ages:
Between 18 years and 60 years
Trial Updated:
03/25/2025
Locations: University of California, San Diego, San Diego, California
Conditions: Obesity, Bariatric Surgery, Sleeve Gastrectomy, Gastroesophageal Reflux Disease
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InfasurfAero™ Versus Sham Treatment in Preterm Newborns with RDS
NCT05960929
Recruiting
The purpose of this clinical study is to determine the effectiveness and safety of Infasurf® administered through the InfasurfAero™, a novel oral airway delivery device specifically designed to give Infasurf in a less complicated way and without the need for a breathing tube or interrupting nasal respiratory support.
Gender:
ALL
Ages:
Between 29 weeks and 36 weeks
Trial Updated:
03/25/2025
Locations: Sharp Mary Birch Hospital for Women & Newborns, San Diego, California
Conditions: Respiratory Distress Syndrome (Neonatal), Intubation Complication, Death; Neonatal
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Comprehensive Computed Tomography Guidance of Coronary Bypass Graft Surgery
NCT03894423
Recruiting
Apply CT angiography, CT perfusion imaging and advanced image processing techniques to improve revascularization decision-making and surgical strategies in patients undergoing coronary artery bypass graft surgery.
Gender:
ALL
Ages:
40 years and above
Trial Updated:
03/25/2025
Locations: University of California San Diego, San Diego, California
Conditions: CAD, Atheroscleroses, Coronary, Computed Tomography, Coronary Artery Bypass
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Ramucirumab Plus Pembrolizumab vs Usual Care for Treatment of Stage IV or Recurrent Non-Small Cell Lung Cancer Following Immunotherapy, Pragmatica-Lung Study
NCT05633602
Recruiting
This phase III trial compares the effect of the combination of ramucirumab and pembrolizumab versus standard of care chemotherapy for the treatment of non-small cell lung cancer that is stage IV or that has come back after a period of improvement (recurrent). Ramucirumab is a monoclonal antibody that may prevent the growth of new blood vessels that tumors need to grow. Immunotherapy with monoclonal antibodies, such as pembrolizumab, may help the body's immune system attack the cancer, and may in... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
03/25/2025
Locations: Kaiser Permanente-San Diego Zion, San Diego, California
Conditions: Recurrent Lung Non-Small Cell Carcinoma, Stage IV Lung Cancer AJCC v8
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Ketogenic Diet and Brain Response in Anorexia Nervosa
NCT06540703
Recruiting
This is a longitudinal study with an open design in weight recovered anorexia nervosa (wrAN) individuals. Healthy controls (HC) will also be assessed. Study participants will be carefully assessed and will have 18F-fluorodeoxyglucose (\[18F\]FDG) positron emission tomography (PET) scans for assessment of regional brain glucose uptake. The wrAN group will be compared to healthy controls. Participants in the wrAN group will then complete 14 weeks of therapeutic ketogenic diet (TKD). At the end of... Read More
Gender:
ALL
Ages:
Between 18 years and 45 years
Trial Updated:
03/25/2025
Locations: University of California San Diego, San Diego, California
Conditions: Anorexia Nervosa
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Natural History Study of Patients with HPDL Mutations
NCT05848271
Recruiting
This study uses medical records that allow retrospective data extraction of clinical manifestation to assess the natural history of HPDL mutations
Gender:
ALL
Ages:
All
Trial Updated:
03/25/2025
Locations: Eun Hae Lee, San Diego, California
Conditions: Mitochondrial Encephalomyopathies, Hereditary Spastic Paraplegia, Spastic Paraplegia, White Matter Disease, Neonatal Encephalopathy, Mutation, Genetic Disease
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An INTERNATIONAL, OBSERVATIONAL, BLINDED STUDY to ASSESS the PERFORMANCE of the CORDIO HEARO SYSTEM
NCT06378632
Recruiting
Study Design: This is an international, multicenter, observational, non-interventional, prospective, blinded, single-arm, two-period study, to collect patient utterances that will be retrospectively analyzed to determine the sensitivity and UPNR of the HearO system.
Gender:
ALL
Ages:
22 years and above
Trial Updated:
03/25/2025
Locations: VA San Diego, San Diego, California
Conditions: Heart Failure
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Evaluate REC-4881 in Patients with FAP
NCT05552755
Recruiting
This is a multicenter, two-part trial in participants with Familial Adenomatous Polyposis (FAP).
Gender:
ALL
Ages:
55 years and above
Trial Updated:
03/24/2025
Locations: Medical Associates Research Group, San Diego, California
Conditions: Familial Adenomatous Polyposis
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Efficacy and Safety Study of Narsoplimab in Pediatric Patients With High-Risk Hematopoietic Stem Cell Transplant TMA
NCT05855083
Recruiting
The purpose of this study is to evaluate the safety and efficacy of narsoplimab in pediatric patients with thrombotic microangiopathies (TMA) following hematopoietic stem cell transplant (HSCT).
Gender:
ALL
Ages:
Between 28 days and 17 years
Trial Updated:
03/24/2025
Locations: Omeros Investigational Site, San Diego, California
Conditions: Thrombotic Microangiopathies, Hematopoietic Stem Cell Transplantation
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TRIcvalve BiCAVal Valve System for Severe Tricuspid Regurgitation (TRICAV-I)
NCT06137807
Recruiting
The TricValve® Transcatheter Bicaval Valve System is a bicaval transcatheter tricuspid valve replacement system, which includes the TricValve® Transcatheter Bicaval Valve for superior vena cava (SVC) and the TricValve® Transcatheter Bicaval Valve for inferior vena cava (IVC). The TricValve® Transcatheter Bicaval Valves are pre-mounted into the TricValve® Delivery System which is used for percutaneous access and delivery of the TricValve® Transcatheter Bicaval Valve in the vena cava. The system i... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
03/24/2025
Locations: Scripps Memorial Hospital La Jolla, San Diego, California
Conditions: Tricuspid Regurgitation, Tricuspid Valve Disease
Register for Updates
Beta-Agonist Versus OnabotulinumtoxinA Trial for Urgency Urinary Incontinence
NCT05806164
Recruiting
The goal of this clinical trial is to compare treatment outcomes between an oral medication (beta agonist) versus onabotulinumtoxinA injections in women with urgency urinary incontinence (UUI). Participants will be randomly selected to receive one of the two treatments. The primary outcome measure will be at 3 months, and women will be followed for a total of 12 months. Based on patient expert input, there are 2 primary outcomes: Treatment satisfaction and urinary symptom severity.
Gender:
FEMALE
Ages:
18 years and above
Trial Updated:
03/24/2025
Locations: University of California, San Diego, San Diego, California
Conditions: Urgency Urinary Incontinence
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Study of the Efficacy and Safety of Inhaled Treprostinil in Subjects With Progressive Pulmonary Fibrosis (TETON-PPF)
NCT05943535
Recruiting
Study RIN-PF-305 is designed to evaluate the safety and efficacy of inhaled treprostinil in subjects with progressive pulmonary fibrosis (PPF) over a 52-week period.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
03/24/2025
Locations: Paradigm Clinical Research, San Diego, California
Conditions: Progressive Pulmonary Fibrosis, Interstitial Lung Disease
Register for Updates