There are currently 707 clinical trials in San Diego, California looking for participants to engage in research studies. Trials are conducted at various facilities, including University of California, San Diego, Rady Children's Hospital - San Diego, GSK Investigational Site and Naval Medical Center - San Diego. Whether you're a healthy volunteer looking to participate in paid medical research or seeking trials related to a specific condition, the city provides a diverse range of opportunities near you.
ARTEMIS - A Research Study to Look at How Ziltivekimab Works Compared to Placebo in People With a Heart Attack
Recruiting
The research study is being done to see if ziltivekimab can be used to treat people who were admitted to hospital because of a heart attack. Ziltivekimab might reduce development of heart disease, thereby preventing new heart attacks or strokes. Participants will either get ziltivekimab (active medicine) or placebo (a dummy medicine which has no effect on the body). Which treatment participants get is decided by chance. The chance of getting ziltivekimab or placebo is the same. The participant w... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
03/02/2025
Locations: UCSD Medical Center, San Diego, California +2 locations
Conditions: Cardiovascular Risk, Acute Myocardial Infarction (AMI)
A Study to Compare the Efficacy and Safety of SCENESSE and Narrow-Band Ultraviolet (NB-UVB) Light Versus NB-UVB Light Alone in Patients with Vitiligo
Recruiting
The CUV105 study will assess the efficacy and safety of afamelanotide and NB-UVB light in patients with vitiligo on the body and face versus NB-UVB light alone.
Gender:
ALL
Ages:
12 years and above
Trial Updated:
02/28/2025
Locations: CLINUVEL site, San Diego, California
Conditions: Vitiligo
Efficacy and Safety of GSK4527226 [AL101] in Participants With Early Alzheimer's Disease
Recruiting
The aim of this study is to assess the efficacy and safety of GSK4527226 in participants with early Alzheimer's Disease (AD) (including mild cognitive impairment \[MCI\] and mild dementia due to AD) of 2 dose levels of GSK4527226 compared to placebo.
Gender:
ALL
Ages:
Between 50 years and 85 years
Trial Updated:
02/28/2025
Locations: GSK Investigational Site, San Diego, California
Conditions: Alzheimer's Disease
Lumbar Drain Vs Extraventricular Drain to Prevent Vasospasm in Subarachnoid Hemorrhage
Recruiting
Vasospasm is a common complication after rupture of intracranial aneurysms causing devastating neurologic deficits and death. Vasospasm has been directly associated with the amount of subarachnoid blood inside the basal cisterns. Prior literature has attempted to refine treatment of ruptured intracranial aneurysms but does not have clear guidelines on the optimal method to drain subarachnoid blood. Two methods, extraventricular drain (EVD) and lumbar drain (LD) have been compared retrospectively... Read More
Gender:
ALL
Ages:
Between 18 years and 110 years
Trial Updated:
02/28/2025
Locations: UCSD Medical Center, San Diego, California
Conditions: Vasospasm, Intracranial, Subarachnoid Hemorrhage
Safety and Efficacy of the VERTICA® RF Device for the Treatment of ED
Recruiting
Adult subjects with mild to moderate and moderate ED who meet the study eligibility criteria will be enrolled in the study. The enrolled subjects will be randomized by a 1:1 ratio to receive the Active or Sham VERTICA® treatment. Baseline assessments will include collection of demographic data, medical history, concomitant medications and baseline clinical examinations. The initial treatment session will be performed in a clinical setting simulating home use to determine proper device use and to... Read More
Gender:
MALE
Ages:
Between 22 years and 85 years
Trial Updated:
02/27/2025
Locations: San Diego Sexual Medicine, San Diego, California
Conditions: Erectile Dysfunction
A Study of Baricitinib in Participants With Rheumatoid Arthritis
Recruiting
This post-marketing study is designed to compare the safety of baricitinib versus tumor necrosis factor (TNF) inhibitors with respect to venous thromboembolic events (VTEs) when given to participants with rheumatoid arthritis (RA).
Gender:
ALL
Ages:
18 years and above
Trial Updated:
02/27/2025
Locations: Purushotham & Akther Kotha MD Inc, San Diego, California
Conditions: Rheumatoid Arthritis
A Study of ELAPRASE in Treatment-naïve Participants With Hunter Syndrome (Mucopolysaccharidosis [MPS] II)
Recruiting
The main aim of this study is to evaluate the ability of a prophylactic immune tolerizing regimen (ITR) to prevent or reduce the development of high titer anti-idursulfase antibodies in treatment-naïve participants with Hunter syndrome. In this open label, single arm study, all participants will receive ELAPRASE treatment and a prophylactic ITR. Participants will be treated with ELAPRASE for up to 104 weeks. The prophylactic ITR will start 1 day prior to the start of ELAPRASE. The prophylactic... Read More
Gender:
MALE
Ages:
6 years and below
Trial Updated:
02/27/2025
Locations: Rady Childrens Hospital San Diego - PIN, San Diego, California
Conditions: Mucopolysaccharidosis (MPS), Hunter Syndrome
Dose-finding, Pharmacokinetics, and Safety of VABOMERE in Pediatric Subjects With Bacterial Infections
Recruiting
A single dose infusion of Vabomere (meropenem-vaborbactam) is being tested for dose-finding, pharmacokinetics, safety, and tolerability in pediatric subjects from birth to less than 18 years of age with serious bacterial infections
Gender:
ALL
Ages:
17 years and below
Trial Updated:
02/27/2025
Locations: Rady Children's Hospital San Diego, San Diego, California
Conditions: Bacterial Infections
A Study of Lebrikizumab in Adult Participants With Perennial Allergic Rhinitis (PREPARED-1)
Recruiting
The main purpose of this study is to evaluate the efficacy and safety of lebrikizumab in adult participants with perennial allergic rhinitis. The study will last about 18 months
Gender:
ALL
Ages:
18 years and above
Trial Updated:
02/27/2025
Locations: Allergy and Asthma, San Diego, California
Conditions: Perennial Allergic Rhinitis (PAR)
Open-Label, Dose-Finding, Pharmacokinetics, Safety and Tolerability Study of Oritavancin in Pediatric Patients With Suspected or Confirmed Bacterial Infections
Recruiting
The purpose of this Phase 1 trial is to evaluate the pharmacokinetics, safety and tolerability of oritavancin in patients \<18 years old with a confirmed or suspected bacterial infection.
Gender:
ALL
Ages:
18 years and below
Trial Updated:
02/27/2025
Locations: Rady Children's Hospital, San Diego, California
Conditions: Gram Positive Bacterial Infections
Androgen Effects on the Reproductive Neuroendocrine Axis
Recruiting
This research study investigates whether male-level exogenous androgens inhibit the reproductive neuroendocrine axis in otherwise healthy (non-PCOS) females.
Gender:
FEMALE
Ages:
Between 18 years and 35 years
Trial Updated:
02/26/2025
Locations: University of California San Diego, San Diego, California
Conditions: Transgenderism, Reproductive Issues
Enhancing Rehabilitation for Veterans With Serious Mental Illness
Recruiting
This study addresses the critical need for innovative therapeutic interventions in Veterans with serious mental illnesses (SMI) receiving care in VA Psychosocial Rehabilitation and Recovery Centers (PRRCs). The vast majority of individuals with SMI suffer from cognitive impairments, leading to chronic functional disability, and impaired outcomes, causing a significant strain on support networks and the VA healthcare system. This study aims to introduce an innovative mental health therapy, Target... Read More
Gender:
ALL
Ages:
Between 18 years and 75 years
Trial Updated:
02/26/2025
Locations: VA San Diego Healthcare System, San Diego, CA, San Diego, California
Conditions: Schizophrenia, Psychosis, Serious Mental Illness, PTSD, Schizoaffective Disorder, Bipolar Disorder