There are currently 778 clinical trials in San Diego, California looking for participants to engage in research studies. Trials are conducted at various facilities, including University of California, San Diego, Rady Children's Hospital San Diego, GSK Investigational Site and Naval Medical Center San Diego. Whether you're a healthy volunteer looking to participate in paid medical research or seeking trials related to a specific condition, the city provides a diverse range of opportunities near you.
A Study of Pirtobrutinib (LOXO-305) Versus Ibrutinib in Participants With Chronic Lymphocytic Leukemia (CLL)/Small Lymphocytic Lymphoma (SLL)
NCT05254743
Recruiting
The purpose of this study is to compare the efficacy and safety of pirtobruitinib (LOXO-305) to ibrutinib in participants with CLL/SLL. Participants may or may not have already had treatment for their cancer. Participation could last up to six years.
Gender:
All
Ages:
18 years and above
Trial Updated:
05/10/2024
Locations: Sharp Memorial Hospital, San Diego, California
Conditions: Chronic Lymphocytic Leukemia, Leukemia, Lymphocytic, Leukemia, B-cell, Small Lymphocytic Lymphoma
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Reducing Posttraumatic Stress Disorder (PTSD) Symptoms in First Responders and Frontline Health Care Workers
NCT05751473
Recruiting
This study addresses PTSD symptoms in First Responders and Healthcare workers. Specifically, it tests whether a brief PTSD treatment (talk therapy) effectively treats PTSD when provided to First Responders and Healthcare workers by counselors in Employee Assistance Programs (EAPs). The central hypothesis is that the PTSD treatment, Prolonged Exposure for Primary Care (PE-PC), will reduce PTSD symptoms and improve functioning, compared to EAP Treatment as Usual (TAU).
Gender:
All
Ages:
18 years and above
Trial Updated:
05/09/2024
Locations: Sharp Healthcare, San Diego, California
Conditions: Post Traumatic Stress Disorder
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A Study to Test a Medicine (Fitusiran) Injected Under the Skin for Preventing Bleeding Episodes in Male Adolescent or Adult Participants With Severe Hemophilia
NCT05662319
Recruiting
This is a multicenter, multinational, open-label, one-way cross-over, Phase 3, single-arm study for treatment of hemophilia. The purpose of this study is to measure the frequency of treated bleeding episodes with fitusiran in male adult and adolescent (≥12 years old) participants with hemophilia A or B, with or without inhibitory antibodies to factor VIII or IX who have switched from their prior standard of care treatment. The total study duration will be up to approximately 50 months (200 wee... Read More
Gender:
Male
Ages:
12 years and above
Trial Updated:
05/09/2024
Locations: University of California San Diego Site Number : 8400011, San Diego, California
Conditions: Hemophilia
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Elucidating TAAR-1, Dopamine, and Norepinephrine in Binge Eating Disorder Using Solriamfetol
NCT06413433
Recruiting
ENGAGE (Elucidating TAAR-1, Dopamine, and Norepinephrine in Binge Eating Disorder Using Solriamfetol) is a Phase 3, randomized, double-blind, placebo-controlled, multicenter trial to assess the efficacy and safety of solriamfetol for the treatment of binge eating disorder (BED) in adults.
Gender:
All
Ages:
Between 18 years and 55 years
Trial Updated:
05/09/2024
Locations: Clinical Research Site, San Diego, California
Conditions: Binge-Eating Disorder
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A Gene Transfer Therapy Study to Evaluate the Safety and Efficacy of Delandistrogene Moxeparvovec (SRP-9001) in Non-Ambulatory and Ambulatory Participants With Duchenne Muscular Dystrophy (DMD)
NCT05881408
Recruiting
The study will evaluate the safety and efficacy of delandistrogene moxeparvovec gene transfer therapy in non-ambulatory and ambulatory males with DMD. This is a randomized, double-blind, placebo-controlled 2-part study. Participants will be in the study for approximately 128 weeks. All participants will have the opportunity to receive intravenous (IV) delandistrogene moxeparvovec in either Part 1 or Part 2.
Gender:
Male
Ages:
All
Trial Updated:
05/09/2024
Locations: Rady Children's Hospital-San Diego, San Diego, California
Conditions: Duchenne Muscular Dystrophy
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Safety Study of CC-93538 in Adult and Adolescent Participants With Eosinophilic Esophagitis
NCT04991935
Recruiting
This study is an open-label, uncontrolled study design to evaluate the long-term safety and tolerability of treatment with CC-93538. The study will enroll participants who participated in the CC-93538-EE-001 or CC-93538-DDI-001 studies.
Gender:
All
Ages:
Between 12 years and 75 years
Trial Updated:
05/09/2024
Locations: SDG Clinical Research, Inc., San Diego, California +1 locations
Conditions: Eosinophilic Esophagitis
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A Study to Evaluate the Efficacy of AXS-05 Compared to Bupropion in Preventing the Relapse of Depressive Symptoms
NCT06223880
Recruiting
This is a randomized, double-blind, active-controlled, multi-center study to evaluate the efficacy of AXS-05, compared to bupropion, in preventing the relapse of depressive symptoms in subjects with major depressive disorder (MDD) who have responded to treatment with AXS-05.
Gender:
All
Ages:
Between 18 years and 65 years
Trial Updated:
05/09/2024
Locations: Clinical Research Site, San Diego, California
Conditions: Major Depressive Disorder
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A Study to Evaluate the Efficacy, Safety, and Pharmacokinetics of Lacosamide in Neonates With Repeated Electroencephalographic Neonatal Seizures
NCT04519645
Recruiting
The purpose of the study is to evaluate the efficacy of lacosamide (LCM) versus an Active Comparator chosen based on standard of care (StOC) in severe and nonsevere seizure burden (defined as total minutes of electroencephalographic neonatal seizures (ENS) per hour) in neonates with seizures that are not adequately controlled with previous anti-epileptic drug (AED) treatment.
Gender:
All
Ages:
28 days and below
Trial Updated:
05/08/2024
Locations: Sp0968 121, San Diego, California +1 locations
Conditions: Electroencephalographic Neonatal Seizures, Epilepsy
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A Study of NOE-115 in Women With Vasomotor Symptoms Due to Menopause
NCT06385795
Recruiting
The purpose of this study is to determine the safety, tolerability, and preliminary effectiveness of NOE-115 on moderate to severe vasomotor symptoms (hot flashes) due to menopause in women.
Gender:
Female
Ages:
Between 45 years and 60 years
Trial Updated:
05/07/2024
Locations: Noema PMM-201 Site #104, San Diego, California
Conditions: Menopause Syndrome, Menopause, Hot Flashes
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Collection of Samples USOPTIVAL Study
NCT04792684
Recruiting
A prospective multi-center observational study. The study will enroll eligible subjects from the United States to optimize the biomarker panel and evaluate the performance of a cfDNA marker panel selected by the Sponsor for CRC and advanced adenoma detection.
Gender:
All
Ages:
Between 45 years and 84 years
Trial Updated:
05/06/2024
Locations: Precision Research Institute, San Diego, California +1 locations
Conditions: Colorectal Cancer (CRC), Advanced Adenomas (AA)
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Families, Responsibility, Education, Support, and Health for Executive Function
NCT05165511
Recruiting
The pilot study will be a one group open-label treatment program and will be used to refine a parent-based behavioral treatment enhanced with executive-function training (PBT-EF) for children with comorbid overweight or obesity and Attention-Deficit Hyperactivity Disorder (ADHD).
Gender:
All
Ages:
Between 8 years and 12 years
Trial Updated:
05/06/2024
Locations: UCSD Center for Healthy Eating and Activity Research (CHEAR), San Diego, California
Conditions: Overweight and Obesity, Attention-Deficit Hyperactivity Disorder
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A Systems Analysis and Improvement Approach for Optimizing HIV Service Delivery in Syringe Services Programs
NCT06025435
Recruiting
The goal of this clinical trial is to assess the effectiveness of an evidence-based, organizational-level implementation strategy, the Systems Analysis and Improvement Approach, in improving HIV service delivery (SAIA-SSP-HIV) in U.S. syringe services programs (SSPs). The main questions it aims to answer are: Does SAIA-SSP-HIV improve delivery of HIV services (including the proportion of SSP participants receiving HIV testing) compared to implementation as usual (IAU)? Does SAIA-SSP-HIV result... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
05/06/2024
Locations: University of California, San Diego, San Diego, California
Conditions: HIV Infections
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