There are currently 715 clinical trials in San Diego, California looking for participants to engage in research studies. Trials are conducted at various facilities, including University of California, San Diego, Rady Children's Hospital - San Diego, GSK Investigational Site and Naval Medical Center - San Diego. Whether you're a healthy volunteer looking to participate in paid medical research or seeking trials related to a specific condition, the city provides a diverse range of opportunities near you.
Natural History Study in Pediatric Patients With MYBPC3 Mutation-associated Cardiomyopathy
NCT05112237
Recruiting
The objective of this study is to collect information on patients with cardiomyopathy (CM) due to mutations in the MYBPC3 gene, to evaluate their disease course, burden of illness, risk factors for this disease, and the quality of life (QoL). This study will also collect information on treatments, procedures and outcome in infants and children up to 18 yrs who have this mutation.
Gender:
ALL
Ages:
Between 0 years and 18 years
Trial Updated:
11/11/2024
Locations: Rady Children's Hospital - San Diego, San Diego, California
Conditions: Cardiomyopathy
Register for Updates
Clinical and Basic Investigations Into Congenital Disorders of Glycosylation
NCT04199000
Recruiting
The purpose of this research is to study the natural history of congenital disorders of glycosylation and its causes and treatments.
Gender:
ALL
Ages:
All
Trial Updated:
11/07/2024
Locations: Rady Children's Hospital, San Diego, California
Conditions: Congenital Disorders of Glycosylation
Register for Updates
ART-Pro: Clinical Trial Evaluating Biparametric MRI and Advanced, Quantitative Diffusion MRI for Detection of Prostate Cancer
NCT06579417
Recruiting
This is a multicenter, multinational trial to evaluate advanced MRI techniques for improved detection of clinically significant prostate cancer (csPCa). The study will enroll 500 participants at 5 clinical centers (100 participants per center). The current standard MRI technique for prostate cancer screening is multiparametric MRI (mpMRI), but two drawbacks include need for intravenous (IV) contrast and dependence on radiologist expertise. The investigators expect that the combination of two oth... Read More
Gender:
MALE
Ages:
18 years and above
Trial Updated:
11/04/2024
Locations: University of California San Diego, San Diego, California
Conditions: Prostate Cancer
Register for Updates
Effect of Anti-inflammatory Diet in Osteoarthritis
NCT06080347
Recruiting
In a previous exploratory study, the investigators observed an effect on disease activity outcomes of anti-inflammatory diet. The investigators also observed change in microbiome and circulating metabolites. The current study will determine whether or not the addition of anti-inflammatory diet improves the clinical outcomes in participants with Osteoarthritis, and the role of microbiome and circulating metabolites.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
10/31/2024
Locations: University of California, San Diego, California
Conditions: Osteoarthritis, Knee
Register for Updates
Mechanisms of Exposure Therapy for OCD
NCT06173752
Recruiting
Exposure therapy is the most effective treatment available for obsessive compulsive disorder, yet up to 50% of patients do not recover because the mechanisms underlying successful response are poorly understood, leading to significant variability in how clinicians conduct exposure therapy. The main purpose of this study is to determine which target mechanisms are most critical to engage in real-world exposure sessions to produce good treatment outcomes. Adult participants (N = 400) with Obsessiv... Read More
Gender:
ALL
Ages:
Between 18 years and 65 years
Trial Updated:
10/30/2024
Locations: Center for Understanding and Treating Anxiety, San Diego, California
Conditions: Obsessive-Compulsive Disorder
Register for Updates
Feasibility Study for Bevonescein-Assisted Nerve Visualization in Head & Neck Surgery
NCT06227585
Recruiting
A feasibility study to evaluate the usability of the REVEAL 475 system in patients treated with bevonescein for nerve visualization during surgery.
Gender:
ALL
Ages:
16 years and above
Trial Updated:
10/29/2024
Locations: Jacobs Medical Center at UC San Diego Health, San Diego, California
Conditions: Head and Neck Surgery
Register for Updates
A Study of Bevonescein in Patients Undergoing Abdominopelvic Surgery
NCT06662097
Recruiting
Feasibility study of Bevonescein to highlight Nerves and Ureter in patients undergoing Minimally Invasive Surgery
Gender:
ALL
Ages:
18 years and above
Trial Updated:
10/25/2024
Locations: University of California San Diego, San Diego, California
Conditions: Surgery, Nerve Injury, Imaging
Register for Updates
Preventing Liver Cancer Mortality Through Imaging With Ultrasound vs. MRI
NCT05486572
Recruiting
The study is a randomized trial of two different screening methods for early detection of liver cancer in patients with cirrhosis of the liver. The goal of PREMIUM is to compare an abbreviated version of the diagnostic gold standard for HCC (aMRI) +AFP to the standard-of-care screening (US+AFP) in patients at high risk of developing HCC. The investigators hypothesize that HCC will be detected at earlier stages, allowing for more curative treatments and resulting in a reduction in HCC-related mor... Read More
Gender:
ALL
Ages:
Between 18 years and 75 years
Trial Updated:
10/24/2024
Locations: VA San Diego Healthcare System, San Diego, CA, San Diego, California
Conditions: Carcinoma, Hepatocellular, Cirrhosis
Register for Updates
Study of Personalized Cancer Therapy to Determine Response and Toxicity
NCT02478931
Recruiting
The purpose of this study is to learn more about personalized cancer therapy including response to treatment and side effects. Information about the tests and treatments a person received, or will receive, for their cancer will be collected from medical records to help the researchers determine whether or not patients respond better when their physicians choose to treat them according to the genetic makeup of their tumor. Optional research tests may be performed on tissue, body cavity fluid, blo... Read More
Gender:
ALL
Ages:
7 years and above
Trial Updated:
10/23/2024
Locations: Rady Children's Hospital, San Diego, San Diego, California
Conditions: Cancer
Register for Updates
The Acute and Accumulative Effects of Snack Foods on Exercise Recovery
NCT06363409
Recruiting
The purpose of the research is two-fold. One goal is to determine if post-exercise almond or cereal bar consumption can promote muscle gain as well as increasing muscular strength throughout an eight-week weight training program. The other goal is to assess the short-term effects of almonds or cereal bar on recovery that may explain the overall long-term adaptations.
Gender:
ALL
Ages:
Between 18 years and 35 years
Trial Updated:
10/15/2024
Locations: San Diego State University, San Diego, California
Conditions: Muscle Strength
Register for Updates
Effects of Common Meals on Appetite and Satiety
NCT06472011
Recruiting
The objectives of this study are to assess the impacts of meals composed of lean steak and potatoes (with a small portion of broccoli) in comparison to other common entrée/starch food combinations on metabolic and appetite responses.
Gender:
ALL
Ages:
Between 18 years and 50 years
Trial Updated:
10/15/2024
Locations: San Diego State University, San Diego, California
Conditions: Healthy
Register for Updates
More Fresh Fruit and Vegetable Prescription Program for Families with Type 2 Diabetes Mellitus
NCT05138432
Recruiting
Rady Children's Hospital San Diego (RCHSD), UCSD Division of Child and Community Health and the Center for Community Health, and Northgate Gonzalez (NG) Markets will collaborate to create a Produce Prescription Program (Fruit and Vegetable Prescription Program) to be implemented in the RCHSD Diabetes Clinic. We will provide families on Medi-Cal who have a child with T2DM with a fruit and vegetable prescription (FVRx) which will enhance their ability to purchase GusNIP-eligible fresh fruits and v... Read More
Gender:
ALL
Ages:
18 years and below
Trial Updated:
10/13/2024
Locations: Rady Children's Hospital San Diego, San Diego, California
Conditions: Type 2 Diabetes
Register for Updates