There are currently 782 clinical trials in San Diego, California looking for participants to engage in research studies. Trials are conducted at various facilities, including University of California, San Diego, Rady Children's Hospital San Diego, GSK Investigational Site and Naval Medical Center San Diego. Whether you're a healthy volunteer looking to participate in paid medical research or seeking trials related to a specific condition, the city provides a diverse range of opportunities near you.
Evaluation of The Comfort of Orthokeratology Lenses Fit Using A New Software
NCT05389072
Recruiting
As new orthokeratology fitting software emerges onto the market, it is of interest to assess their usefulness in guiding eye practitioners with lens fit. The goal of this study is to evaluate the comfort of Paragon orthokeratology lenses when they are fit using the new Procornea software.
Gender:
All
Ages:
Between 6 years and 35 years
Trial Updated:
09/22/2022
Locations: 4S Eyecare and Optometry, San Diego, California
Conditions: Myopia
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Safety, Tolerability, and Efficacy of AXA1125 in NASH With Fibrosis
NCT04880187
Recruiting
This study will compare the effects of AXA1125, an orally active mixture of amino acids, compared to placebo, on improving fat and inflammation (steatohepatitis) as well as fibrosis in subjects with non alcoholic steatohepatitis (NASH). as well as the safety and tolerability of AXA1125. Subjects will take one of two different doses of AXA1125 or a placebo twice daily, and a liver biopsy will be done at the beginning and end of the 48-week study.
Gender:
All
Ages:
18 years and above
Trial Updated:
09/07/2022
Locations: Precision Research Institute, LLC, San Diego, California
Conditions: Non Alcoholic Steatohepatitis (NASH)
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Biofeedback for Psoriasis
NCT05506644
Recruiting
We are conducting a proof-of-concept trial to study the impact of HRV-biofeedback, a mind-body technique designed to improve stress resilience, on the quality of life, mood, and clinical skin severity of patients with psoriasis.
Gender:
All
Ages:
18 years and above
Trial Updated:
08/16/2022
Locations: Bastyr University Clinic, San Diego, California
Conditions: Psoriasis, Psoriasis Vulgaris, Psychophysiological Disorder, Anxiety, Depression, Psychological Stress, Physiological Stress, Quality of Life, Skin Disorder, Skin Diseases
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Diagnostic Accuracy and Safety of DBV1605 for the Diagnosis of Non-IgE Mediated Cow's Milk Allergy in Children
NCT04492683
Recruiting
Study to assess the diagnostic accuracy (sensitivity, specificity, positive and negative predictive value) of DBV1605 for the diagnosis of non-Immunoglobulin E (IgE) mediated cow's milk allergy (CMA) in children with symptoms suggestive of non-IgE mediated CMA.
Gender:
All
Ages:
Between 29 days and 24 months
Trial Updated:
08/09/2022
Locations: University of California, Rady Children's Hospital, San Diego, California
Conditions: Cow's Milk Allergy
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North American Mitochondrial Disease Consortium Patient Registry and Biorepository (NAMDC)
NCT01694940
Recruiting
The North American Mitochondrial Disease Consortium (NAMDC) maintains a patient contact registry and tissue biorepository for patients with mitochondrial disorders.
Gender:
All
Ages:
All
Trial Updated:
07/28/2022
Locations: University of California San Diego, San Diego, California
Conditions: Mitochondrial Disorders, Mitochondrial Genetic Disorders, Mitochondrial Diseases, Disorder of Mitochondrial Respiratory Chain Complexes, Deletion and Duplication of Mitochondrial DNA
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MIP Versus PCNL for Kidney Stone Disease
NCT04767919
Recruiting
The decision to use standard percutaneous nephrolithotomy (PCNL) versus mini-percutaneous nephrolithotomy (MIP) has been a subject of much debate in the urological community. The investigators propose a randomized controlled trial to compare the operative outcomes and complications of mini-percutaneous nephrolithotomy (mini-PCNL) versus standard PCNL for renal stones. The results of this study will help guide the decision making regarding these two procedures in the US population and provide fur... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
07/12/2022
Locations: University of California, San Diego, Medical Center, San Diego, California
Conditions: Kidney Stone
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Phase 2 Study of Efficacy and Safety of AK120, in Subjects With Moderate-to-Severe Atopic Dermatitis
NCT05048056
Recruiting
This is a phase 2, multi-center, randomized, placebo-controlled, double-blind, parallel-group, dose-ranging study, conducted in subjects with moderate-to-severe atopic dermatitis.
Gender:
All
Ages:
18 years and above
Trial Updated:
07/04/2022
Locations: AkesoBio Investigative Site 2021, San Diego, California +1 locations
Conditions: Atopic Dermatitis
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Erector Spinae Plane Block Catheters and Intrathecal Morphine for Hepatic Resection
NCT04849455
Recruiting
To determine whether the addition of erector spinae plane (ESP) catheters to existing multimodal analgesic regimen with intrathecal morphine provides superior postoperative analgesia in patients undergoing hepatic resection compared with patients not receiving ESP catheters.
Gender:
All
Ages:
18 years and above
Trial Updated:
06/06/2022
Locations: University of California, San Diego, San Diego, California
Conditions: Hepatic Resection, Acute Pain, Anesthesia, Anesthesia, Local
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UCSD Image-Guided Cognitive-Sparing Radiosurgery for Brain Metastases
NCT04343157
Recruiting
In this proposal, the investigators introduce advanced diffusion and volumetric imaging techniques along with innovative, automated image parcellation methods to identify critical brain regions, incorporate into cognitive-sparing SRS, and analyze biomarkers of radiation response. This work will advance the investigators' understanding of neurocognitive changes after brain SRS and help create interventions that preserve cognitive-function in brain metastases patients.
Gender:
All
Ages:
18 years and above
Trial Updated:
05/17/2022
Locations: Moores Cancer Center, San Diego, California
Conditions: Brain Metastases, Adult, Neurocognitive Function, Cancer
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Struvite Stones Antibiotic Study
NCT02375295
Recruiting
The aim of this research is to determine an effective antibiotic regimen following definitive surgical therapy of kidney stones caused by bacterial infection (struvite stones).
Gender:
All
Ages:
19 years and above
Trial Updated:
05/16/2022
Locations: University California San Diego, San Diego, California
Conditions: Kidney Stones
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The Natural History of Danon Disease
NCT03766386
Recruiting
Danon disease (DD) is a rare, X-linked disorder associated with severe cardiomyopathy, and in many cases, skeletal myopathy, and cognitive impairment caused by mutations in the LAMP2 gene. There is still uncertainty regarding the natural history of DD because of its rarity. This study aims to determine the natural history of DD through the collection and analysis of retrospective and prospective data. To achieve this, the investigators will perform surveys and obtain medical records from DD pat... Read More
Gender:
All
Ages:
Between 0 years and 100 years
Trial Updated:
05/11/2022
Locations: University of California, San Diego, San Diego, California
Conditions: Danon Disease
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Trauma Informed Guilt Reduction Therapy
NCT02512445
Recruiting
The goal of this project is to determine if a 6-session psychotherapy intervention will help Veterans feel less deployment-related guilt and less distress related to their guilt. Half of the participants will receive the guilt focused intervention and half will receive a supportive intervention. A supplemental pilot study added in FY2021 will examine the intervention for pandemic-related guilt events.
Gender:
All
Ages:
18 years and above
Trial Updated:
05/04/2022
Locations: VA San Diego Healthcare System, San Diego, California
Conditions: Guilt, Shame, Post-traumatic Stress Disorders
Register for Updates