The city of Aurora, Colorado, currently has 5 active clinical trials seeking participants for Alzheimer's Disease research studies.
Phase II Trial to Evaluate Safety and Efficacy of GM-CSF/Sargramostim in Alzheimer's Disease
Recruiting
A medicine that is FDA-approved for bone marrow stimulation (called sargramostim) will be tested for its safety and efficacy in individuals with mild-to-moderate Alzheimer's disease over a six month treatment period.
Gender:
All
Ages:
Between 60 years and 85 years
Trial Updated:
06/20/2024
Locations: University of Colorado Anschutz Medical Campus, Aurora, Colorado
Conditions: Alzheimer Disease
Intervention to Collect and Utilize Sexual Orientation and Gender Identity (SOGI) Information in Hospice
Recruiting
Older sexual and gender minority (SGM) patients are at risk for receiving inequitable end-of-life care; those with Alzheimer's disease and related dementias (ADRD) are at particularly high risk. Failure to collect and integrate sexual orientation and gender identity (SOGI) data to identify patients' informal support systems may have adverse health consequences for SGM older adults, particularly for those dependent on informal caregivers to provide in-home support and assist with activities of da... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
06/18/2024
Locations: University of Colorado, Aurora, Colorado
Conditions: Sexual and Gender Minorities, Hospice, Alzheimer's Disease and Related Dementias
A Donanemab (LY3002813) Prevention Study in Participants With Alzheimer's Disease (TRAILBLAZER-ALZ 3)
Recruiting
The main purpose of this study is to evaluate the safety and efficacy of donanemab in participants with preclinical Alzheimer's Disease (AD).
Gender:
All
Ages:
Between 65 years and 80 years
Trial Updated:
06/17/2024
Locations: Care Access - Aurora, Aurora, Colorado
Conditions: Alzheimer Disease
Rocky Mountain Alzheimer's Disease Center Longitudinal Biomarker and Clinical Phenotyping Study
Recruiting
This study plans to establish a large bank of blood, cerebral spinal fluid (CSF), imaging, and clinical data. These data and samples will be used for future research into the causes of Alzheimer's disease (AD), Down Syndrome (DS) and other diseases that cause thinking and memory problems. This future research will also study how treatments for these diseases work. This research may help develop new treatments for some diseases of the nervous system and help understand these diseases better.
Gender:
All
Ages:
18 years and above
Trial Updated:
03/29/2024
Locations: University of Colorado, Denver, Aurora, Colorado
Conditions: Alzheimer Disease, Down Syndrome, Mild Cognitive Impairment
Trial-Ready Cohort-Down Syndrome (TRC-DS)
Recruiting
The purpose of the Trial-Ready Cohort - Down Syndrome (TRC-DS) is to enroll 120 healthy adults with Down syndrome (DS), between the ages of 25-55, into a trial ready cohort (TRC), and up to 250 participants in total including co-enrolled in the Alzheimer Biomarkers Consortium - Down Syndrome (ABC-DS) study. Participants enrolled in the TRC-DS will undergo longitudinal cognitive and clinical assessment, genetic and biomarker testing, as well as imaging and biospecimen collection. Using these outc... Read More
Gender:
All
Ages:
Between 25 years and 55 years
Trial Updated:
03/06/2024
Locations: Linda Crnic Institute for Down Syndrome, University of Colorado, Aurora, Colorado
Conditions: Down Syndrome, Alzheimer Disease, Dementia