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Aging Clinical Trials
A listing of 142 Aging clinical trials actively recruiting volunteers for paid trials and research studies in various therapeutic areas.
25 - 36 of 142
There are currently 142 active clinical trials seeking participants for Aging research studies. The states with the highest number of trials for Aging participants are California, Texas, Florida and Massachusetts.
Featured Trial
Paid Clinical Studies Nationwide
Recruiting
Nationwide clinical trials offered in your area. Some trials offering up to several thousand dollars in compensation for participation.
Featured Trial
Chronic Cough Study
Recruiting
Are you tired of living with chronic cough? The ASPIRE Study is now looking to enroll people from all backgrounds to help research potential new treatment options for chronic cough. You are under no obligation to take part and health insurance is not required. Find out more today! We’d love to hear from you.
Conditions:
Chronic Cough
Refractory or Unexplained Chronic Cough
Cough
Asthma
Allergic Asthma
Featured Trial
Studying an Investigational Virus Vaccine
Recruiting
The main objectives of this study are to assess the safety and effectiveness of an investigational vaccine aimed at preventing norovirus, commonly known as the stomach flu. Participants will be randomly assigned to receive either the investigational vaccine or a placebo. Should you express interest, you will be contacted directly by the research site, which will provide further details and answer any questions you may have about study requirements, risks/benefits, and any compensation.
Conditions:
Healthy
Interested in vaccine studies
All Conditions
Preventative Trials
Featured Trial
NAD+ Aging Study
Recruiting
The HEALING Lab at the University of Rhode Island is seeking volunteers between the age of 40-80 for a NAD+ aging study. Participants will receive $300 for completing a 5-week study, which involves taking an oral supplement (either a sugar pill or NAD+ supplement) for 4 weeks between two in-person sessions. To participate in this study, you cannot be taking hormones, pregnant, or breastfeeding.
Conditions:
Healthy
Healthy Volunteers
Arlington Aging Study
Recruiting
The goal of this observational study is to learn about the mechanisms causing functional decline with age, using exercise science, neuroscience, and remote monitoring.
Specific aims include:
Aim 1: Advance knowledge of the biology of aging and its impact on the prevention, progression, and prognosis of disease and disability.
Aim 2: Determine the effects of personal and societal factors on aging.
Aim 3: Examine the influence of racial/ethnic and sex differences on the biology of aging and it... Read More
Gender:
ALL
Ages:
Between 18 years and 80 years
Trial Updated:
02/27/2025
Locations: University of Texas Arlington, Arlington, Texas
Conditions: Aging
Effect of mTOR Inhibition & Other Metabolism Modulating Interventions on the Elderly [SubStudy Rapa & cMRI to Evaluate Cardiac Function]
Recruiting
The ability to mount an effective immune response declines with age, leaving the elderly increasingly susceptible to infectious diseases and cancer. Rapamycin, an FDA approved drug to prevent transplant rejection, increases the lifespan and healthspan of mice and ameliorates age-related declines in immune responsiveness, cancer survival, and cognition in laboratory animals. Investigators are conducting a translational trial to test whether rapamycin also improves life functions in humans focusin... Read More
Gender:
MALE
Ages:
Between 70 years and 95 years
Trial Updated:
02/27/2025
Locations: Audie L. Murphy Memorial Veterans Hospital, San Antonio, Texas +1 locations
Conditions: Aging
Inspiratory Muscle Strength Training for Lowering Blood Pressure and Improving Endothelial Function in Postmenopausal Women: Comparison With "Standard of Care" Aerobic Exercise
Recruiting
High blood pressure (BP) is the major modifiable risk factor for cardiovascular diseases (CVD) and related health conditions, particularly among postmenopausal (PM) women. In adults age ≥50 years this risk is primarily driven by above-normal systolic BP (SBP ≥120 mmHg), as diastolic BP plateaus, then decreases in older adulthood. Although SBP is lower in premenopausal women vs. age-matched men, SBP reaches, then surpasses men after age 60. As such, \>75% of PM women in the U.S. have above-normal... Read More
Gender:
FEMALE
Ages:
50 years and above
Trial Updated:
02/26/2025
Locations: Integrative Physiology of Aging Laboratory, Boulder, Colorado
Conditions: Aging, Blood Pressure, Endothelial Dysfunction, Hypertension
Executive Functioning Training Study
Recruiting
Cognitive aging in people with HIV (PWH) is of increasing concern for several reasons: 1) between 52%-59% of PWH experience cognitive impairment known as HIV-Associated Neurocognitive Disorder (HAND) which impacts everyday functioning and quality of life; 2) HAND increases in severity and prevalence with age; and 3) 70% of PWH in the United States will be 50 and older by 2030. Fortunately, cognitive training programs can individually target specific cognitive impairments in PWH and possibly redu... Read More
Gender:
ALL
Ages:
40 years and above
Trial Updated:
02/22/2025
Locations: UAB School of Nursing, Birmingham, Alabama
Conditions: Aging, Cognitive Function Abnormal, Cognitive Performance, Cognitive Training, Older Adults
Influence of Brain Oscillation-Dependent TMS on Motor Function
Recruiting
Background:
When people have a stroke, they often have difficulty moving their arms and hands. Transcranial magnetic stimulation (TMS) can improve how well people with and without stroke can move their arms and hands. But the effects of TMS are minor, and it doesn t work for everyone. Researchers want to study how to time brain stimulation so that the effects are more consistent.
Objective:
To understand how the brain responds to transcranial magnetic stimulation so that treatments for people... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
02/22/2025
Locations: National Institutes of Health Clinical Center, Bethesda, Maryland
Conditions: Healthy, Stroke, Normal Physiology, Aging
Nicotinamide Riboside for Treating Elevated Systolic Blood Pressure and Arterial Stiffness in Middle-aged and Older Adults
Recruiting
Aging is the primary risk factor for cardiovascular diseases (CVD), the number one cause of death in developed societies. Systolic blood pressure (SBP) increase with age and is a key intermediary factor linking aging to increased CVD risk. The primary mechanisms underlying the age-associated increase in SBP is stiffening of the large elastic arteries, which is mediated by increases in oxidative stress, inflammation, and vascular smooth muscle tone. Regular caloric restriction is effective at low... Read More
Gender:
ALL
Ages:
50 years and above
Trial Updated:
02/19/2025
Locations: Integrative Physiology of Aging Laboratory, Boulder, Colorado
Conditions: Hypertension, Aging
Optimizing Strength Training in Older Adults
Recruiting
The objective of the current study is to determine whether lifting lighter loads close to failure improves strength training adaptations and function in older adults. The main questions it aims to answer are:
1. The effect of light loads on physical function
2. The effect of light loads on muscle mass, power, and strength
Researchers will compare a light-load, high-repetition program to a standard strength training program. Participants will perform supervised strength training twice per week... Read More
Gender:
ALL
Ages:
65 years and above
Trial Updated:
02/19/2025
Locations: Exercise & Aging Lab, Queens College, Flushing, New York
Conditions: Aging
The Role of Sirolimus in Preventing Functional Decline in Older Adults
Recruiting
Aging is associated with progressive impairment of tissue and organ function, resulting in increased susceptibility to chronic disease, frailty and disability. Currently there are limited treatment options to alter this inevitable process. The proposed work has the potential to identify a new therapeutic intervention to decrease aging-related degenerative processes.
Rapamycin or sirolimus is a macrocyclic immunosuppressive drug that inhibits the mammalian target of rapamycin (mTOR). The mammali... Read More
Gender:
ALL
Ages:
Between 65 years and 80 years
Trial Updated:
02/19/2025
Locations: UT Southwestern Medical Center, Dallas, Texas
Conditions: Aging
The Wandering Nerve: Gateway to Boost Alzheimer's Disease Related Cognitive Performance
Recruiting
In this research study the investigators want to find out if a non-invasive electrical brain stimulation method called RAVANS (also called tVNS) can have a beneficial effect on cognition in older individuals. The investigators also want to understand whether certain individual factors contribute to the effect of RAVANS on cognition. RAVANS is only used in research studies.
Gender:
ALL
Ages:
Between 60 years and 85 years
Trial Updated:
02/18/2025
Locations: Massachusetts General Hospital, Charlestown, Massachusetts
Conditions: Aging
Impact of Extreme Heat on Myocardial Blood Flow and Flow Reserve in Young and Older Adults
Recruiting
Extreme heat causes a disproportionate number of hospitalizations and deaths in older adults relative to any other age group. Importantly, many hospitalizations and deaths are primarily due to cardiovascular events such as myocardial infarction. Previous data indicate that older adults have attenuated skin blood flow and sweating responses when exposed to heat, resulting greater increase in core body temperature. Despite these observations, relatively little is known about the risk for myocardia... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
02/18/2025
Locations: Texas Health Presbyterian Hospital Dallas, Dallas, Texas
Conditions: Aging, Heat Stress, Hyperthermia, Heat Strain
Preliminary Testing of Cafe Move for Primary Prevention of Physical Frailty
Recruiting
This project explores a novel means of health promotion and prevention of age-related physical frailty, which is designed to overcome barriers to access and promote autonomy in managing physical health.
Gender:
ALL
Ages:
Between 50 years and 85 years
Trial Updated:
02/13/2025
Locations: University of Montana, Missoula, Montana
Conditions: Aging
Everolimus Aging Study
Recruiting
The objective of this project is to determine if mTORC1 inhibition by 24 weeks of daily (0.5 mg/day) or weekly (5 mg/week) everolimus can safely improve physiological and molecular hallmarks of aging in humans. Participants who are 55-80 years old and insulin resistant or prediabetic will be randomized to treatment and can expect to be on study for up to approximately 38 weeks. Participants aged 18-35 will not receive the intervention and can expect to be on study for up to approximately 8 weeks... Read More
Gender:
ALL
Ages:
Between 18 years and 80 years
Trial Updated:
02/11/2025
Locations: University of Wisconsin-Madison, Madison, Wisconsin
Conditions: Aging, Insulin Resistance
25 - 36 of 142