There are currently 141 active clinical trials seeking participants for Aging research studies. The states with the highest number of trials for Aging participants are California, Texas, Florida and Massachusetts.
Baltimore Longitudinal Study of Aging
Recruiting
Background: - The Baltimore Longitudinal Study of Aging (BLSA) is a clinical research program on human aging that began in 1958. Volunteers of different ages join the study when they are healthy, and have follow-up visits for life. Visits last for multiple days. Participants are evaluated for many physical elements as well as for brain function. Physical tests are given. Information on mood, personality, and social aspects of life is also collected. This program has contributed more than any ot... Read More
Gender:
ALL
Ages:
Between 20 years and 120 years
Trial Updated:
05/22/2025
Locations: National Institute of Aging, Clinical Research Unit, Baltimore, Maryland
Conditions: Aging
Effect of Walnuts on Cognitive Function and Gut Microbiome in Older Adults
Recruiting
The purpose of this study is to examine the impact of daily consumption of walnuts for 12 weeks on cognitive function, markers of inflammation and oxidative stress, and the gut microbiome in healthy adults age 55 years and older.
Gender:
ALL
Ages:
55 years and above
Trial Updated:
05/22/2025
Locations: Oregon State University, Corvallis, Oregon
Conditions: Aging, Inflammation Biomarkers
Effect of Snacks on Aging
Recruiting
The purpose of this study is to determine if daily consumption of 2 oz of pecans compared to 3.5 oz pretzel snacks for 12 weeks will 1) contribute to the body's ability to protect itself from oxidative damage (caused by oxygen radicals created by ultraviolet (UV) B light) by evaluating skin resistance to UV light irritation, skin fats/oils degradation and "rusting", and oxidative damage to the skin genes; and 2) explore the mechanisms of how snack consumption may affect aging by analyzing blood... Read More
Gender:
FEMALE
Ages:
Between 55 years and 75 years
Trial Updated:
05/21/2025
Locations: UCLA Center for Human Nutrition, Los Angeles, California
Conditions: Aging
Computerized Tests of Cognitive Decline in Presymptomatic Alzheimer's Disease
Recruiting
The investigators will study performance on computerized cognitive tasks in healthy participants of different ages to gather normative data for newly developed computerized cognitive tests. These tests are designed to permit the early detection of individuals at risk of age-related cognitive decline.
Gender:
ALL
Ages:
Between 18 years and 89 years
Trial Updated:
05/19/2025
Locations: Neurobehavioral Systems, Inc., Berkeley, California
Conditions: Alzheimer Disease, Aging, Cognitive Decline
Leveraging Social Networks to Improve Sleep and Mindfulness Among Older Adults in Residential Housing Facilities
Recruiting
The aim of this study is to design a sleep and mindfulness intervention to improve sleep, quality of life, and cognitive function among older adults.
Gender:
ALL
Ages:
55 years and above
Trial Updated:
05/16/2025
Locations: Brigham and Women's Hospital, Boston, Massachusetts
Conditions: Aging, Cognitive Impairment, Sleep
Examining the Effects of Theta Burst TMS on Brain Connectivity and Balance Ability in Older Adults With Balance Problems
Recruiting
The goal of this study is to learn if manipulating the brain using magnets works to treat balance impairment, a major cause of falls, in older adults with balance problems. The technique to manipulate the brain using magnets is known as transcranial magnetic stimulation or TMS. The main questions this study aims to answer are: * How does TMS change communication between brain areas? * Does TMS improve balance ability in older adults with balance problems? Researchers will compare the TMS group... Read More
Gender:
ALL
Ages:
65 years and above
Trial Updated:
05/14/2025
Locations: The Center for Neuromotor and Biomechanics Research at the University of Houston, Houston, Texas
Conditions: Aging, Balance Deficits
Heterogeneity of Vascular Adaptations to Exercise With Aging in Women and Men
Recruiting
The goal of the proposed study is to understand the reasons for the variability in aerobic exercise (AE) training benefits on the vasculature in middle-age and older (MA/O) adults, including differences between men and women. To achieve this goal, a mechanistic randomized controlled (RCT) will be conducted, in which adults are randomized to 12-weeks intervention of AE or no-exercise Control. Our overall hypothesis is that the exercise response variation in vascular benefits is related to age and... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
05/14/2025
Locations: University of Colorado Anschutz Medical Center, Clinical Translational Research Center and Exercise Research Laboratory, Aurora, Colorado
Conditions: Aging, Physical Activity, Vascular Health
Spinal Networks of Balance Learning and Retention in Older Adults
Recruiting
Age-related balance and walking issues increase fall risks, leading to injuries, higher healthcare costs, reduced quality of life, and increased morbidity/mortality rates. Preserving functional ability is a crucial public health priority, with the potential to reduce healthcare costs and enhance older adults' quality of life. Declines in balance and walking ability threaten independence. These declines are attributed to spinal network impairments and may be mitigated by targeted interventions ai... Read More
Gender:
ALL
Ages:
Between 65 years and 95 years
Trial Updated:
05/07/2025
Locations: Malcom Randall VA Medical Center Brain Rehabilitation Research Center, Gainesville, Florida
Conditions: Aging
Implementation of Neuromuscular Electrical Stimulation After Total Knee Arthroplasty
Recruiting
Patients experience dramatic quadriceps strength loss after total knee replacement, which contributes to persistent weakness and reduced long-term function after surgery. Neuromuscular electrical stimulation (NMES) reduces quadriceps weakness and improves patient function after knee replacement, but it is drastically underused in rehabilitation practice. This randomized trial will examine the effectiveness and feasibility of a comprehensive strategy for implementing neuromuscular electrical stim... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
05/07/2025
Locations: UCHealth, Aurora, Colorado +2 locations
Conditions: Total Knee Arthroplasty, Functional Recovery, Aging, Physical Therapy
C-Protein in Fatigue and Aging
Recruiting
This study is investigating changes to the proteins in skeletal muscle that contribute to reduced muscle size and muscle function that occurs with aging.
Gender:
ALL
Ages:
Between 18 years and 80 years
Trial Updated:
05/06/2025
Locations: University of Oregon, Eugene, Oregon
Conditions: Aging, Muscle Atrophy or Weakness, Sarcopenia in Elderly, Sarcopenia
Arterial Stiffness and Blood Pressure
Recruiting
Hypertension is a common and treatable disorder that remains the leading preventable cause of heart disease. Blood pressure treatment relies mainly on upper arm blood pressure readings and ignores blood vessel physiology and underlying individual genetic information. Older Veterans with hypertension are less likely to be treated to goal blood pressure because there are conflicting recommendations for what constitutes "optimal" in older adults. The investigators have developed a novel way to non-... Read More
Gender:
ALL
Ages:
60 years and above
Trial Updated:
05/05/2025
Locations: Birmingham VA Medical Center, Birmingham, AL, Birmingham, Alabama +2 locations
Conditions: Hypertension, Vascular Stiffness, Aging
Clean Hands Accessible and Manageable for Patients (CHAMPs)
Recruiting
This study proposes the novel use of a bedrail-affixed technology-based patient hand hygiene system with verbal and visual reminders to improve hospitalized older adults' self-management of hand hygiene practice, which in return reduces harmful germs found on older adult's hands that lead to infections.
Gender:
ALL
Ages:
65 years and above
Trial Updated:
05/02/2025
Locations: Lous Stokes Cleveland VA Medical Center, Cleveland, Ohio +1 locations
Conditions: Pathogen Transmission, Patient Participation, Aging