There are currently 156 active clinical trials seeking participants for Anxiety research studies. The states with the highest number of trials for Anxiety participants are California, Massachusetts, Ontario and New York.
PRISM for Depression and Anxiety in Young Adults With Cancer
NCT06502483
Recruiting
This research study is being done to test the feasibility of an existing supportive program (PRISM) to address psychological symptoms (i.e., depressive and anxiety symptoms) that young adult participants diagnosed with cancer or desmoid tumor may experience. The name of the intervention used in this research study is: -Promoting Resilience in Stress Management (PRISM) Program
Gender:
ALL
Ages:
Between 18 years and 39 years
Trial Updated:
08/07/2025
Locations: Dana-Farber Cancer Institute, Brighton, Massachusetts
Conditions: Cancer Diagnosis, Non-Metastatic Neoplasm, Anxiety, Anxiety Disorders, Depression, Depressive Disorder, Depression, Anxiety, Desmoid
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Autonomous Digital CBT Intervention for Opioid Use Disorder in Individuals With Co-Occurring Internalizing Disorders
NCT06545071
Recruiting
The primary objective of this protocol is to implement the UG3 phase (Phase 1) of a National Institute on Drug Abuse (NIDA) UG3/UH3 grant (RFA-DA-23-049). This phase is dedicated to the pilot testing of NEAT-O, a digital Cognitive Behavioral Therapy (CBT) program tailored for individuals with opioid use disorder (OUD) and concurrent anxiety or mood disorders - collectively referred to as internalizing disorders (INTDs). NEAT-O is based on an empirically supported CBT framework, specifically modi... Read More
Gender:
ALL
Ages:
Between 18 years and 65 years
Trial Updated:
08/06/2025
Locations: University of Minnesota, Minneapolis, Minnesota
Conditions: Opioid Use Disorder, Anxiety, Depression
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Decoding and Modulating Affective Brain States
NCT05437705
Recruiting
The research study is being conducted to study brain patterns of negative emotion and develop personalized brain stimulation protocols to disrupt these patterns with transcranial magnetic stimulation (TMS). First, we will use functional Magnetic Resonance Imaging (fMRI) data to generate a negative affect map for each subject. Then, we will try a variety of repetitive transcranial magnetic stimulation (rTMS) sequences while inside the MRI scanner to determine the optimal and least optimal rTMS fr... Read More
Gender:
ALL
Ages:
Between 18 years and 65 years
Trial Updated:
08/06/2025
Locations: University of Pennsylvania, Philadelphia, Pennsylvania
Conditions: Rumination, Major Depressive Disorder, Anxiety
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Intervention Trial for Healthcare Workers With Anxiety
NCT06460285
Recruiting
The purpose of the study is to conduct an initial test of the efficacy of Emotional Resolution (EmRes) therapy to reduce anxiety in healthcare workers. The investigators hypothesize EmRes will reduce levels of anxiety in participants compared to an active control group engaged in mindfulness-based gratitude.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
08/04/2025
Locations: University of California, Los Angeles, Los Angeles, California
Conditions: Anxiety
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Pilot Effectiveness Trial of an ACT Self-help Workbook Tailored Specifically for Prisons
NCT06162624
Recruiting
The goal of this research study is to adapt an ACT-self-help workbook to the prison setting and determine the feasibility acceptability, and effectiveness of this workbook. Participants can expect to be in the study for 13 weeks.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
08/01/2025
Locations: University of Wisconsin, Madison, Wisconsin
Conditions: Anxiety, Depression, Depression, Anxiety, Anxiety Disorders
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A Behavioral mHealth Intervention for People With HIV With Anxiety and Depression
NCT07112001
Recruiting
This study will adapt and assess the preliminary effectiveness of a community health worker-delivered mental health counselling intervention delivered remotely to reduce anxiety and depression among people with HIV in Florida.
Gender:
ALL
Ages:
Between 18 years and 90 years
Trial Updated:
08/01/2025
Locations: University of Florida, Gainesville, Florida
Conditions: HIV, Depression, Anxiety
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Feasibility of Virtual, Tailored, Music-Based Relaxation for Anxiety in Adolescent and Young Adult Cancer Survivors
NCT05911269
Recruiting
Demonstrate the feasibility of conducting an eight-week, (45 min/week), theory driven, virtually-delivered, tailored music-based relaxation (TiMBRe) intervention to decrease anxiety in adolescent and young adult (AYA) cancer survivors with clinically-relevant anxiety.
Gender:
ALL
Ages:
Between 15 years and 39 years
Trial Updated:
07/31/2025
Locations: University of Michigan, Ann Arbor, Michigan
Conditions: Anxiety
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Hypnosis-Based Machine Learning Biomarker Study
NCT07102810
Recruiting
This study seeks to contribute to the growing body of literature on hypnosis by providing robust, data-driven insights into the physiological mechanisms underlying trance states. The integration of electroencephalogram (EEG) and other wearable-derived physiological data will offer a comprehensive assessment of the changes that occur during a standardized hypnosis protocol: the Harvard Group Scale of Hypnotic Susceptibility (HGSHS:A). The results of this study are intended to facilitate derivatio... Read More
Gender:
ALL
Ages:
Between 18 years and 65 years
Trial Updated:
07/30/2025
Locations: Mount Sinai Hospital, New York, New York
Conditions: Disorder; Trance, Anxiety
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S.T.A.N.D. Alacrity Center Signature Project
NCT05591937
Recruiting
The purpose of this study is to evaluate clinical decision-making algorithms for (a) triaging to level of care and (b) adapting level of care in a low income, highly diverse sample of community college students at East Los Angeles College (ELAC). The target enrollment is 200 participants per year, for five years (N=1000). Participants are between the ages of 18 and 40 years and will be randomized into either symptom severity decision-making (SSD) or data-driven decision-making (DDD). Participan... Read More
Gender:
ALL
Ages:
Between 18 years and 40 years
Trial Updated:
07/29/2025
Locations: East Los Angeles College, Los Angeles, California
Conditions: Depression, Anxiety
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Project 2: Optimizing Engagement and Outcomes in STAND Digital Therapy
NCT05908565
Recruiting
The goal is to optimize peer coaching in order to optimize engagement and outcomes in digital therapy. The unmet mental health needs of community college students are staggering and a growing body of research demonstrates that therapy provided digitally with the assistance of trained community members without advanced degrees in mental health is an effective and scalable way to address these needs. Despite being effective for improving symptoms and functioning in those who engage in it, uptake a... Read More
Gender:
ALL
Ages:
Between 18 years and 40 years
Trial Updated:
07/29/2025
Locations: East Los Angeles College, Los Angeles, California
Conditions: Depression, Anxiety
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Type I Hybrid Effectiveness-Implementation Trial of Primary Care Brief Mindfulness Training for Veterans
NCT06162741
Recruiting
The VA wants to understand what type of integrative and whole health approaches are helpful for Veterans. The study is comparing two primary care based mental health treatments, a mindfulness class that teaches mindfulness meditation and a problem-solving class that teaches problem-solving skills and how to build resilience, for Veterans who are experiencing symptoms of anxiety, depression, and/or PTSD. The goal of the study is to understand if the classes reduce symptoms of anxiety, depression,... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
07/29/2025
Locations: Phoenix VA Health Care System, Phoenix, AZ, Phoenix, Arizona +3 locations
Conditions: Post Traumatic Stress Disorder (PTSD), Depression, Anxiety
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Cannabis for Palliative Care in Cancer
NCT06266611
Recruiting
Many cancer patients suffer from pain, sleep, and mood problems and are using cannabis to relieve these symptoms. Cannabis may provide such relief but may also produce negative side effects including cognitive impairment, an especially problematic issue for cancer patients, indicating more research on cannabis use in the cancer context is required. In this endeavor, the present study seeks to compare the use of hemp-derived CBD (Cannabidiol) with and without THC (Delta-9-tetrahydrocannabinol) ve... Read More
Gender:
ALL
Ages:
25 years and above
Trial Updated:
07/29/2025
Locations: Anschutz Health Sciences Building, Aurora, Colorado
Conditions: Sleep, Anxiety, Depression, Pain
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