There are currently 154 active clinical trials seeking participants for Cardiovascular Diseases research studies. The states with the highest number of trials for Cardiovascular Diseases participants are Florida, California, Texas and New York.
Aging, Geriatric Syndromes and Clonal Hematopoiesis
NCT02604563
Recruiting
In this study the investigators will incorporate a wide range of clinical variables associated with aging and cardiovascular disease to determine whether they are associated with mutation status independent of chronologic age. Clinically, aging can be operationalized using geriatric assessment, which entails a comprehensive multi-dimensional assessment of the health of an older adult, including measures of comorbidity, polypharmacy, functional status, cognition, depression, falls, social activit... Read More
Gender:
All
Ages:
50 years and above
Trial Updated:
04/23/2024
Locations: Washington University School of Medicine, Saint Louis, Missouri
Conditions: Geriatrics, Aged, Geriatric Syndromes, Cardiovascular Diseases
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Personalized GI Motility Responses to Diet
NCT06386471
Recruiting
The goal of this randomized, crossover, clinical trial is to link: 1) gastrointestinal motility patterns induced by acute consumption of whole and refined grains, 2) enteric microbial production of bioactive metabolites, and 3) circulating postprandial appearance of metabolites important to cardiometabolic health including glucose, triglycerides, and cholesterol. Participants will be asked to consume a Smartpill monitoring device that records metrics of gastrointestinal motility in response to... Read More
Gender:
All
Ages:
Between 21 years and 63 years
Trial Updated:
04/23/2024
Locations: University of Illinois at Urbana-Champaign, Urbana, Illinois
Conditions: Nutritional and Metabolic Diseases, Gastrointestinal Dysfunction, Cardiovascular Diseases, Dysbiosis
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Dietary Nitrate Functional Gum Effect on Gingivitis and Heart Health
NCT06029283
Recruiting
The purpose of this research is to determine the effects of a chewing gum containing dietary nitrate to gingival and heart health. Dietary nitrates are commonly found in leafy vegetables and beets. The information learned from the study may help further understand the interconnection of oral health and heart health. The study is looking for individuals who present with mild to moderate gum irritation or bleeding. In the study participants will be randomized into either a group that will use a c... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
04/20/2024
Locations: University of Maryland School of Dentistry, Baltimore, Maryland
Conditions: Gingivitis, Cardiovascular Diseases, Gingival Diseases, Gingival Bleeding, Periodontal Diseases
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Accessing Mobility Using Wearable Sensors
NCT04306588
Recruiting
This study will examine whether wearable sensors can be used to track changes in cognitive-motor performance in response to a disease or an intervention. The investigators specific aims are twofold, first aim to explore whether and how a clinical condition such as Chronic obstructive pulmonary disease (COPD) or Congestive Heart Failure (CHF) may impact motor-cognitive performance measurable using validated wearable devices (e.g., LEGSys, BalanSENS, and Frailty Meter). Second, the investigators... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
04/19/2024
Locations: Michael E. DeBakey Veterans Affairs Medical Center, Houston, Texas
Conditions: COPD, Pulmonary Disease, Pulmonary Restrictive Disease, Congestive Heart Failure, Cardiovascular Diseases
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MoST-Influenced Behavioral Intervention for Walking
NCT05425641
Recruiting
This study is a randomized, factorial experiment using the basic Science of Behavior Change (SOBC) approach to efficiently test the effects of four distinct behavior change techniques (BCTs), goal setting, action planning, self- monitoring and feedback, thought to engage one key behavioral mechanism of action (MoA) for improving daily walking by at least 1000 steps per day in persons who have been objectively verified as sedentary and are at risk for cardiovascular disease.
Gender:
All
Ages:
Between 18 years and 74 years
Trial Updated:
04/18/2024
Locations: Institute of Health System Science, New York, New York
Conditions: Cardiovascular Diseases, Physical Inactivity
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NAN-101 in Patients With Class III Heart Failure
NCT04179643
Recruiting
This is a Phase 1, prospective, multi-center, open-label, sequential dose escalation study to explore the safety, feasibility, and efficacy of a single intracoronary infusion of BNP116.sc-CMV.I1c in patients with NYHA Class III heart failure. Patients with symptomatic congestive heart failure will be enrolled until up to 12 subjects have received infusions of investigational product. All patients will be followed until 12 months post treatment intervention, and then undergo long-term follow-up v... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
04/18/2024
Locations: Minneapolis Heart Foundation Institute, Minneapolis, Minnesota +3 locations
Conditions: Congestive Heart Failure, Heart Failure, Heart Disease, Ischemic, Cardiovascular Diseases, Heart Failure, Systolic, Heart Failure，Congestive, Heart Arrhythmia, Heart Failure, Diastolic, Heart; Complications
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Virtual Care Strategies to Improve Participation in Cardiac Rehabilitation Among Veterans
NCT05423158
Recruiting
Home-based CR (HBCR) is an alternative to traditional CR programs that has comparable efficacy in improving morbidity/mortality and increases access to critical services. There is major potential to improve Veteran engagement in CR by combining digital coaching (d-Coaching) with existing VA-supported technologies. The investigator's theory-based intervention targets a critical component of successful CR engagement that is not available through traditional programs: virtual social support through... Read More
Gender:
All
Ages:
21 years and above
Trial Updated:
04/17/2024
Locations: San Francisco VA Medical Center, San Francisco, CA, San Francisco, California +1 locations
Conditions: Cardiovascular Diseases
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A Study Evaluating the Efficacy and Safety of Ralinepag to Improve Treatment Outcomes in PAH Patients
NCT03626688
Recruiting
Study ROR-PH-301, ADVANCE OUTCOMES, is designed to assess the efficacy and safety of ralinepag when added to pulmonary arterial hypertension (PAH) standard of care or PAH-specific background therapy in subjects with World Health Organization (WHO) Group 1 PAH.
Gender:
All
Ages:
18 years and above
Trial Updated:
04/17/2024
Locations: University of Alabama at Birmingham, Birmingham, Alabama +212 locations
Conditions: PAH, Pulmonary Hypertension, Pulmonary Arterial Hypertension, Hypertension, Connective Tissue Diseases, Familial Primary Pulmonary Hypertension, Vascular Diseases, Cardiovascular Diseases, Hypertension, Pulmonary, Lung Diseases, Respiratory Tract Disease
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Highly Processed Foods and Vascular Health
NCT05628350
Recruiting
Age is the primary risk factor for cardiovascular disease (CVD) and age-related vascular dysfunction is considered the key process linking the two. Middle age is a particularly vulnerable period when risk factors exceed diagnostic thresholds and clinical expression of CVD first becomes evident. Ultra-processed foods (UPF) comprise almost 60% of total energy in the standard American diet. The results of observational studies suggest that UPF consumption increases CVD risk, independent of overall... Read More
Gender:
All
Ages:
Between 40 years and 65 years
Trial Updated:
04/15/2024
Locations: Virginia Polytechnic and State University, Blacksburg, Virginia
Conditions: Cardiovascular Diseases
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Evaluating Infrasonic Hemodynography
NCT04636892
Recruiting
This comparative diagnostic accuracy study will determine the accuracy of a noninvasive wearable infrasonic sensor to detect the mechanical, electrical, and hemodynamic function of the cardiovascular system.
Gender:
All
Ages:
All
Trial Updated:
04/15/2024
Locations: Scripps Health, La Jolla, California
Conditions: Aortic Stenosis, Mitral Regurgitation, Pulmonary Hypertension, Heart Failure, Systolic, Cardiovascular Diseases, Coronary Artery Disease
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CommunityRx-Cardiovascular Disease
NCT06264726
Recruiting
The goal of this single arm pre-test post-test design study is to test the impact of providing patients with information about community-based resources to address health-related social needs and cardiometabolic health in rural African American patients. The main question it aims to answer is: • What is the effectiveness of community resource information on patient self-efficacy to use community resources? Participants will be given: A personalized "HealtheRx" resource with information about... Read More
Gender:
All
Ages:
2 years and above
Trial Updated:
04/10/2024
Locations: OIC Family Medical Center - Fairview, Rocky Mount, North Carolina +1 locations
Conditions: Cardiovascular Diseases, Self Efficacy
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Aventus Thrombectomy System Pulmonary Embolism Clinical Study
NCT05907564
Recruiting
Evaluate the safety and efficacy of the Aventus Thrombectomy System for aspiration thrombectomy in subjects with acute pulmonary embolism.
Gender:
All
Ages:
Between 18 years and 80 years
Trial Updated:
04/03/2024
Locations: Honor Health, Scottsdale, Arizona +15 locations
Conditions: Pulmonary Embolism, Embolism, Embolism and Thrombosis, Vascular Diseases, Cardiovascular Diseases, Lung Diseases, Respiratory Tract Diseases
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