There are currently 57 active clinical trials seeking participants for Cerebral Palsy research studies. The states with the highest number of trials for Cerebral Palsy participants are Punjab, California, Ontario and New York.
Cerebral Palsy and the Study of Brain Activity During Motor Tasks
Recruiting
Background: - Two ways to study the brain while people are moving are near-infrared spectroscopy (NIRS) and electroencephalography (EEG). NIRS uses light to look at blood flow in the brain when it is active. EEG records electrical activity in the brain. Both have been used safely for many years, even in very young children. NIRS or EEG can be used while a person is moving to show which parts of the brain are the most active. Researchers want to use NIRS and EEG to study brain activity during mo... Read More
Gender:
ALL
Ages:
Between 5 years and 100 years
Trial Updated:
06/28/2025
Locations: National Institutes of Health Clinical Center, Bethesda, Maryland
Conditions: Cerebral Palsy, Children
Near-infrared Spectroscopy and Electroencephalography to Assess Cortical Activation During Motor Tasks in Infants and Toddlers With and Without Cerebral Palsy
Recruiting
Background: New ways to study the brain as people move include near-infrared spectroscopy (NIRS) and electroencephalography (EEG). NIRS uses laser light shone through the scalp to look at blood flow in the brain which increases with movement. EEG records electrical activity in the brain. Little is known about brain activity while children learn new motor skills. Researchers want to learn more about how small children with and without cerebral palsy use their brain to control their body. This ma... Read More
Gender:
ALL
Ages:
Between 3 months and 5 years
Trial Updated:
06/27/2025
Locations: National Institutes of Health Clinical Center, Bethesda, Maryland
Conditions: Autism, Cerebral Palsy
Feasibility of an In-home Standing and Walking Intervention for Infants With and at High Risk of Cerebral Palsy
Recruiting
The purpose of this study is to evaluate the feasibility and begin to evaluate the effect of an intensive in-home standing and walking intervention for infants with or at high risk of cerebral palsy.
Gender:
ALL
Ages:
Between 5 months and 2 years
Trial Updated:
06/21/2025
Locations: University of Southern California, Los Angeles, California
Conditions: Cerebral Palsy
Promoting Upright Mobility in Infants With Cerebral Palsy Using a Robotic Unweighting System
Recruiting
BabyG is a soft harness attached to a robotic system mounted overhead. While wearing the harness, the infant is free to move around a 10-by-10-foot play area with a padded floor. The harness helps support the infant s weight; it also slows any falls and catches the body before it hits the floor. BabyG can be adjusted to support 5% to 50% of the infant s weight. Participants will be in the study for 24 weeks, including 12 weeks with BabyG training and 12 weeks without. Training will be 90 minute... Read More
Gender:
ALL
Ages:
Between 5 months and 18 months
Trial Updated:
06/13/2025
Locations: National Institutes of Health Clinical Center, Bethesda, Maryland
Conditions: Cerebral Palsy, Physical Therapy Modalities, Brain Injuries
A Novel Program Using Ride-on Toys to Improve Upper Extremity Function in Children With Hemiplegia
Recruiting
The purpose of this study is to assess the feasibility and utility of 2 types of play-based training programs co-delivered by researchers and caregivers within home/community settings to promote arm function among 3-to-8-year-old children with hemiplegia. Specifically, investigators will assess the feasibility of implementation and acceptance/satisfaction associated with a researcher-caregiver co-delivered community-based training program involving either joystick-operated powered ride-on toys (... Read More
Gender:
ALL
Ages:
Between 3 years and 8 years
Trial Updated:
06/04/2025
Locations: Physical Therapy Program, Department of Kinesiology, University of Connecticut, Storrs, Connecticut
Conditions: Hemiplegia, Cerebral Palsy, Children, Only
Virtual A2 Study for At Risk Children
Recruiting
The goal of this behavioral-interventional study is to learn if the Abecedarian Approach implemented virtually for children ages 0-5 with a history of Hypoxic Ischaemic Encephalopathy (HIE) and/or premature birth produces the same effects as when administered at in-person facilities.
Gender:
ALL
Ages:
5 years and below
Trial Updated:
06/02/2025
Locations: University of Wisconsin Madison, Madison, Wisconsin
Conditions: Hypoxic Ischaemic Encephalopathy (HIE), Premature Birth, Cerebral Palsy, Neurological Disorder
Evaluating a New Knee-Ankle-Foot Brace to Improve Gait in Children With Movement Disorders
Recruiting
Background: - Cerebral palsy (CP) is the most common motor disorder in children. CP often causes crouch gait, an abnormal way of walking. Knee crouch has many causes, so no single device or approach works best for everybody. This study s adjustable brace provides many types of walking assistance. Researchers will evaluate brace options to find the best solution for each participant, and whether one solution works best for the group. Objective: - To evaluate a new brace to improve crouch gait... Read More
Gender:
ALL
Ages:
Between 5 years and 100 years
Trial Updated:
05/31/2025
Locations: National Institutes of Health Clinical Center, Bethesda, Maryland
Conditions: Incomplete Spinal Cord Injury, Muscular Dystrophy, Spina Bifida, Cerebral Palsy
Study to Assess the Efficacy, Safety, and Tolerability of Valbenazine for the Treatment of Dyskinesia Due to Cerebral Palsy
Recruiting
The primary objective of this study is to evaluate the efficacy of valbenazine versus placebo on improving chorea in pediatric and adult participants who have dyskinesia due to cerebral palsy (DCP) with choreiform movements.
Gender:
ALL
Ages:
Between 6 years and 70 years
Trial Updated:
05/21/2025
Locations: Neurocrine Clinical Site, San Diego, California +42 locations
Conditions: Dyskinesia, Cerebral Palsy
Measuring Aided Language Development
Recruiting
The focus of the current study is to systematically investigate the psychometric properties of a range of aided language measures, which are based on the Graphic Symbol Utterance and Sentence Development Framework (Binger \& Kent-Walsh).
Gender:
ALL
Ages:
Between 42 months and 60 months
Trial Updated:
05/13/2025
Locations: University of Central Florida - Innovative Center, Orlando, Florida
Conditions: Down Syndrome, Cerebral Palsy, Apraxia of Speech, Speech Sound Disorder, Speech Disorders in Children, Speech and Language Disorder
Investigating New Methods to Study Movement in Children and Young Adults With Movement Disorders.
Recruiting
Background: Cerebral palsy (CP) is the most common motor disorder that affects children. People with CP have weak muscles; they may have trouble controlling the movements of their arms and legs. Researchers have been developing braces called robotic exoskeletons for people with CP. These devices can adapt to the person s movements and help them move better. This natural history study will explore new technologies that may tell us more about how people with CP move and improve how these exoskele... Read More
Gender:
ALL
Ages:
Between 5 years and 25 years
Trial Updated:
05/03/2025
Locations: National Institutes of Health Clinical Center, Bethesda, Maryland
Conditions: Cerebral Palsy
Anatomical and Functional Imaging Correlates of Chronic Pain in Cerebral Palsy
Recruiting
The investigators hope to use MRI biomarkers to identify and characterize sensorimotor network disruption patterns associated with chronic pain and sensory deficits in CP. Investigators will use existing information in the medical record as well as subjective reports from interview, physical exam data, and anatomical and functional MRI data to non-invasively identify brain injury correlates of pain and sensory deficits.
Gender:
ALL
Ages:
8 years and above
Trial Updated:
05/01/2025
Locations: F.M. Kirby Center, Baltimore, Maryland +3 locations
Conditions: Cerebral Palsy, Chronic Pain
Em-power: Maximizing Functional Independence for Children with Severe Cerebral Palsy
Recruiting
For children with severe cerebral palsy, a powered wheelchair (PWC) may provide their only option for functional mobility and independence. PWC use is often restricted to a small percentage of children who can quickly demonstrate proficient PWC skills within a single 30-minute PWC trial. This 2-arm, parallel group, single blinded, pre-test-post-test randomized controlled trial will test our hypothesis that an 8-week PWC skills training intervention will produce greater improvements in children's... Read More
Gender:
ALL
Ages:
Between 5 years and 17 years
Trial Updated:
03/06/2025
Locations: Grand Valley State University, Grand Rapids, Michigan
Conditions: Cerebral Palsy