Chronic Kidney Disease Clinical Trials

A listing of 36 Chronic Kidney Disease clinical trials actively recruiting volunteers for paid trials and research studies in various therapeutic areas.

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There are currently 36 active clinical trials seeking participants for Chronic Kidney Disease research studies. The states with the highest number of trials for Chronic Kidney Disease participants are California, Texas, Florida and New York.

Featured Trial

Chronic Kidney Disease and High Blood Pressure

Recruiting

Conditions:

Kidney Disease

Chronic Kidney Disease

Learn More

* Compensation for time may be available

Featured Trial

Chronic Kidney Disease (CKD) Trials

Recruiting

Chronic Kidney Disease (CKD) trials near you are looking for participants to help push medical research forward. Click through to learn more!

Conditions:

Chronic Kidney Disease (CKD)

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Featured Trial

Paid Clinical Studies Nationwide

Recruiting

Nationwide clinical trials offered in your area. Some trials offering up to several thousand dollars in compensation for participation.

Conditions:

Healthy

Healthy Volunteer Study

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* Compensation for time may be available

Featured Trial

Chronic Cough Clinical Study

Recruiting

We are evaluating an investigational treatment to see if it may help people dealing with chronic cough.
Eligible participants will receive study-related medical care at no cost. You may be compensated for study-related travel and time. Health insurance is not required. If you qualify, you may receive:
Payment up to $1500, which varies by study.

Conditions:

Cough

Chronic Cough

Asthma

Allergic Asthma

Sinusitis

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A Study to Learn About How BAY 3283142 Moves Into, Through, and Out of the Body After a Single Dose in Participants With Reduced Liver Function Compared to Participants With Normal Liver Function

NCT06402721

Recruiting

Researchers are looking for a better way to treat people who have chronic kidney disease (CKD). CKD is a condition in which the kidneys' ability to work properly gradually decreases over time. The kidneys help the body get rid of waste through urine and filter the blood before sending it back to the heart. When kidney function decreases, waste builds up in the body, which can cause various complications. The study treatment, BAY 3283142, is under development to treat CKD. It works by activating a protein called soluble guanylate cyclase (sGC) that generates cGMP - a molecule that relaxes blood vessels and is thought to have beneficial effects in CKD. BAY3283142 is broken down in the liver by a specific enzyme before it is removed from the body. In this study, researchers want to understand how a mild or moderate reduction in liver function affects the blood levels of BAY3283142. The main purpose of this study is to learn how BAY3283142 moves into, through, and out of the body, after a single dose of BAY3283142 in participants with reduced liver function. For this, the researchers will analyze: Area under the curve (AUC): a measure of the total amount of BAY3283142 in participants' blood over time Maximum observed concentration (Cmax): the highest amount of BAY 3283142 in participants' blood The AUC and Cmax values for participants with reduced liver function will be compared with the values for participants with normal liver function. The study participants will be assigned to one of the four treatment groups based on their liver function: Group 1: participants with mild reduction in liver function Group 2: participants with moderate reduction in liver function Groups 3 and 4: participants with normal liver function who will be matched for age, weight, and gender with participants with reduced liver function All participants will take a single dose of BAY3283142 as a tablet by mouth without food. Each participant will be in the study for around 5 to 6 weeks, which includes: a visit within 28 days of starting treatment to confirm if the participant can take part in this study a hospital stay for 7 days during which the participant will be given a single dose of BAY3283142 and the study doctor will monitor the participant's health a visit after 7 to 10 days of taking BAY3283142 during which the study doctor will perform a health check-up on the participant During the study, the doctors and their study team will: check participants' health by performing tests such as blood and urine tests, blood pressure measurements, and checking heart health using an electrocardiogram (ECG) ask the participants questions about how they are feeling and what adverse events they are having An adverse event is any medical problem that a participant has during a study. Doctors keep track of all adverse events, irrespective of whether they think it is related or not to the study treatment. Access to study treatment after the end of this study is not planned. Participants with liver problems can continue taking their other prescribed medicines as usual. Read Less

Gender:

All

Ages:

Between 18 years and 79 years

Trial Updated:

05/28/2024

Locations: Orlando Clinical Research Center (OCRC), Orlando, Florida

Conditions: Chronic Kidney Disease, Hepatic Impairment

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A Natural History Study of Metabolic Sizing in Health and Disease

NCT05398783

Recruiting

Background: Scientists have long used simple measures (such as height and weight) to estimate how much a person s body uses food (calories) as energy, as commonly called the metabolic rate. But metabolism varies among people with similar body sizes. Scientists now believe the old formulas for estimating metabolic rates may not work well for all people. Researchers want to find more accurate ways to measure a person s metabolism. Objective: This natural history study will examine the relations... Read More

Gender:

All

Ages:

Between 2 years and 99 years

Trial Updated:

05/25/2024

Locations: National Institutes of Health Clinical Center, Bethesda, Maryland

Conditions: Metabolic Disorders, Cancer, Chronic Kidney Disease, Diabetes, Normal Physiology

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Effects of Constipation Treatment in Chronic Kidney Disease: A Pilot Feasibility Trial

NCT06123195

Recruiting

Constipation is one of the most prevalent gastrointestinal disorders in patients with chronic kidney disease (CKD) and has been associated with their adverse kidney and cardiovascular outcomes; however, little is known about the effects of constipation treatment on clinical outcomes nor on outcome-related biochemical and microbiological parameters in patients with CKD. The investigators aim to test the feasibility of delivering an intervention with constipation treatment and determine its effect... Read More

Gender:

All

Ages:

18 years and above

Trial Updated:

05/21/2024

Locations: Memphis VA Medical Center, Memphis, Tennessee

Conditions: Chronic Kidney Disease, Constipation

Learn More ›

A Study to Learn More About How Well the Study Treatment Finerenone Works, How Safe it is, How it Moves Into, Through, and Out of the Body, and the Effects it Has on the Body When Taken With an ACE Inhibitor or Angiotensin Receptor Blocker in Children With Chronic Kidney Disease and Proteinuria

NCT05196035

Recruiting

Researchers are looking for a better way to treat children who have chronic kidney disease (CKD), which is long-term kidney disease, and proteinuria, a condition in which a person´s kidneys leak protein into the urine. The kidneys filter waste and fluid from the blood to form urine. In children with CKD, the kidney´s filters do not work as well as they should. This can lead to accumulation of waste and fluid in the body and proteinuria. CKD can lead to other medical problems, such as high blood pressure, also known as hypertension. Vice versa, hypertension and proteinuria can also contribute to worsening of CKD. Therefore, the treatment of CKD aims to control blood pressure and proteinuria. There are treatments available for doctors to prescribe to children with CKD and hypertension and/or proteinuria. These include "angiotensin-converting enzyme inhibitors" (ACEI) and "angiotensin receptor blockers" (ARB). Both ACEI and ARB can improve kidney function by helping the renin-angiotensin-aldosterone system (RAAS) to work normally. The RAAS is a system that works with the kidneys to control blood pressure and the balance of fluid and electrolytes in the blood. In people with CKD, the RAAS is often too active, which can stop the kidneys from working properly and cause hypertension and proteinuria. However, ACEI or ARB treatment alone does not work for all patients with CKD as they only target the angiotensin part of the renin-angiotensin-aldosterone system. The study treatment, finerenone, is expected to help control RAAS overactivation together with an ACEI or ARB. So, the researchers in this study want to learn more about whether finerenone given in addition to either an ACEI or ARB can help their kidney function. The main purpose of this study is to learn more about whether finerenone added to either ACEI or ARB can help reduce the amount of protein in the participants' urine more than a placebo. A placebo looks like a treatment but does not have any medicine in it. Participants will also continue to receive their other medications. To see how the treatment work, the doctors will take samples of the participants' urine to measure their protein levels before and during taking treatment and after their last treatment. In addition, blood samples will be taken to monitor kidney function, electrolytes and the amount of finerenone in the blood as well as for other tests. This study will include children with CKD and proteinuria aged from 6 months up to less than 18 years. The participants will take: either finerenone or the placebo, in addition to either ACEI or ARB, whichever they take as part of their normal treatment Two visits are required up to 104 days, to check whether a child can take part in the treatment phase of the study. If participants qualify for the treatment phase, they will then undergo treatment for about 180 days. During this time, they will visit the study site at least 7 times. During these visits, the participants will: have their blood pressure, heart rate, temperature, height and weight measured have blood and urine samples taken have physical examinations have their heart examined by an electrocardiogram and echocardiography (a sonogram of the heart) answer questions about their medication and whether they have any adverse events , or have their parents or guardians answer answer questions about how they are feeling, or have their parents or guardians answer answer question about how they like the study medication, or have their parents or guardians answer The doctors will keep track of any adverse events. An adverse event is any medical problem that a participant has during a study. Doctors keep track of all adverse events that happen in studies, even if they do not think the adverse events might be related to the study treatments. The doctors will check the participants' health about 30 days after the participants take their last treatment. Read Less

Gender:

All

Ages:

Between 6 months and 17 years

Trial Updated:

05/21/2024

Locations: Phoenix Children's Hospital | Main - Transplant Department, Phoenix, Arizona +146 locations

Phoenix Children's Hospital | Main - Transplant Department, Phoenix, Arizona

University of California San Diego (UCSD), La Jolla, California

Stanford Medicine, Palo Alto, California

Children's Research Institute, Washington, District of Columbia

South Broward Hosp. District dba Memorial Healthcare System, Hollywood, Florida

University of Iowa, Iowa City, Iowa

Johns Hopkins Univ School Med|Johns Hopkins Hosp Dept Gyn/Ob, Baltimore, Maryland

Boston Children's Hospital, Boston, Massachusetts

Children's Mercy Hospital & Clinics, Kansas City, Missouri

Cincinnati Children's Hospital and Medical Center, Cincinnati, Ohio

Cleveland Clinic | Pediatric Nephrology, Cleveland, Ohio

Nationwide Children's Hospital, Columbus, Ohio

Oregon Health and Science Univ | Doernbecher Childrens Hosp, Portland, Oregon

Children's Hospital of Philadelphia, Philadelphia, Pennsylvania

Univ of Texas Health Science Center | Nephrology Res Dept, San Antonio, Texas

Primary Children's Hospital, Salt Lake City, Utah

Seattle Children's Hospital, Seattle, Washington

Hospital Italiano Buenos Aires, Buenos Aires, Ciudad Auton. De Buenos Aires

Hospital General de Ninos Ricardo Gutierrez | Pediatric Nephrology Department, Buenos Aires, Ciudad Auton. De Buenos Aires

Hospital General de Niños Pedro de Elizalde, Ciudad de Buenos Aires, Not set

Centro de Rehabilitacion Cardiovascular | San Luis, Argentina, San Luis, Not set

Clinica de Nefrologia, Urologia y Enfermedades Cardiovascualares - Santa Fe, Argentina, Santa Fe, Not set

The Children's Hospital at Westmead, Westmead, New South Wales

Queensland Children's Hospital, South Brisbane, Queensland

Monash Children's Hospital, Clayton, Victoria

Royal Children's Hospital Melbourne, Parkville, Victoria

Many Locations, Multiple Locations, Not set

Kepler Universitätsklinikum Campus IV, Linz, Oberösterreich

Medizinische Univ Graz | Kinder & Jugendheilkunde, Graz, Steiermark

Many Locations, Multiple Locations, Not set

Uniklinikum Salzburg - Landeskrankenhaus, Salzburg, Not set

AKH Wien | Kinder & Jugendheilkunde, Kindernephrologie, Wien, Not set

Huderf / Ukzkf, Bruxelles - Brussel, Not set

CU Saint-Luc/UZ St-Luc, Bruxelles - Brussel, Not set

UZ Gent, Gent, Not set

UZ Gasthuisberg - Pediatric Nephrology, Leuven, Not set

CHC Montlégia - Pediatrics, Liège, Not set

Many Locations, Multiple Locations, Not set

Alberta Children's Hospital, University of Calgary, Calgary, Alberta

The Hospital for Sick Children (SickKids), Toronto, Ontario

CHU Sainte-Justine, Montreal, Quebec

Many Locations, Multiple Locations, Not set

Vseobecna fakultni nemocnice v Praze, Praha 2, Not set

Fakultni nemocnice v Motole, Praha 5, Not set

Rigshospitalet, Dept Pediatrics & Adelescent Med., Copenhagen, Not set

Many Locations, Multiple Locations, Not set

Odense, HC Andersen, Odense C, Not set

Aarhus Universitetshospital, Skejby, Århus N, Not set

HUS Uusi lastensairaala, Helsinki, Not set

Many Locations, Multiple Locations, Not set

Pediatric Early Phase Trial Unit, Tampere University Hospita, Tampere, Not set

Turun yliopistollinen keskussairaala, Turku, Not set

Hôpital Pellegrin - Bordeaux, BORDEAUX cedex, Not set

CHU de Lyon - Hopital Femme Mère Enfant, Bron, Not set

Hôpital Arnaud de Villeneuve - Montpellier, Montpellier, Not set

Many Locations, Multiple Locations, Not set

Hopital Robert Debre, Paris, Not set

CHU STRASBOURG - Hôpital de Hautepierre, Strasbourg, Not set

Hôpital des Enfants, TOULOUSE Cedex 9, Not set

Universitätsklinikum Heidelberg, Heidelberg, Baden-Württemberg

Universitätsklinikum Erlangen, Erlangen, Bayern

Medizinische Hochschule Hannover (MHH), Hannover, Niedersachsen

Kindernierenzentrum Bonn, Bonn, Nordrhein-Westfalen

Universitätsklinikum Essen, Essen, Nordrhein-Westfalen

Universitätsklinikum Münster (UKM), Münster, Nordrhein-Westfalen

Charité / Pädiatrie, Berlin, Not set

Universitätsklinikum Hamburg Eppendorf (UKE), Hamburg, Not set

Many Locations, Multiple Locations, Not set

AGIA SOFIA Children's Hospital, Athens, Not set

Children's Hospital of Athens P&A Kyriakou, Athens, Not set

University General Hospital of Heraklion, Crete, Not set

Ioannina University General Hospital, Ioannina, Not set

Many Locations, Multiple Locations, Not set

Hippokration General Hospital of Thessaloniki, Thessaloniki, Not set

Semmelweis University, Budapest, Not set

Debreceni Egyetem Klinikai Kozpont, Debrecen, Not set

Many Locations, Multiple Locations, Not set

Pecsi Tudomanyegyetem Klinikai Kozpont, Pecs, Not set

SZTE ÁOK Szent Györgyi Albert Klinikai Kozpont, Szeged, Not set

Soroka University Medical Center, Beer Sheva, Not set

Wilf Children's Hospital Shaare Zedek Medical Center, Jerusalem, Not set

Many Locations, Multiple Locations, Not set

Health Corporation of Galilee Medical Center, Nahariya, Not set

Clalit Health Services Schneider Children's Medical Center, Petach Tikva, Not set

Dana-Dwek Children's Hospital, Tel Aviv, Not set

A.O.U. di Bologna Policlinico S.Orsola Malpighi, Bologna, Emilia-Romagna

IRCCS Ospedale Pediatrico Bambino Gesù, Roma, Lazio

IRCCS Istituto Giannina Gaslini, Genova, Liguria

Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milano, Lombardia

Many Locations, Multiple Locations, Not set

Kyungpook National University Hospital, Daegu, Daegu Gwang''yeogsi

Seoul National University Bundang Hospital, Seongnam-si, Gyeonggido

Pusan National University Yangsan Hospital, Yangsan-si, Gyeongsangnamdo

Korea University Guro Hospital, Seoul, Seoul Teugbyeolsi

Seoul National University Hospital, Seoul, Seoul Teugbyeolsi

Many Locations, Multiple Locations, Not set

Hospital of LT University of Health Sciences Kaunas Clinics, Kaunas, Not set

Klaipeda Children's Hospital, Klaipeda, Not set

Many Locations, Multiple Locations, Not set

Vilnius University Hospital Santaros Klinikos Children's Hospital Paediatrics Centre, Vilnius, Not set

Universitair Medisch Centrum Groningen, Groningen, Not set

Many Locations, Multiple Locations, Not set

Universitair Medisch Centrum St. Radboud, Nijmegen, Not set

University Medical Center Utrecht, Utrecht, Not set

Uniwersytecki Dzieciecy Szpital Kliniczny im. L. Zamenhofa, Bialystok, Not set

Uniwersyteckie Centrum Kliniczne, Gdansk, Not set

Uniwersytecki Szpital Dzieciecy w Krakowie, Krakow, Not set

Instytut Centrum Zdrowia Matki Polki, Lodz, Not set

Many Locations, Multiple Locations, Not set

Dzieciecy Szpital Kliniczny im. Jozefa Brudzinskiego, Warszawa, Not set

Instytut "Pomnik - Centrum Zdrowia Dziecka", Warszawa, Not set

Uniwersytecki Szpital Kliniczny UM we Wroclawiu, Wroclaw, Not set

Centro Clinico Academico Braga | Braga, Portugal, Braga, Not set

CHULN - H. Sta.Maria (Centro de Investigacao Clinica), Lisboa, Not set

Many Locations, Multiple Locations, Not set

Centro Hospitalar Universitario do Porto, Porto, Not set

Hospital de Sant Joan de Déu, Esplugues de LLobregat, Barcelona

Ciutat Sanitaria i Universitaria de la Vall d'Hebron, Barcelona, Not set

H Univ. 12 de Octubre | Unidad Pediátrica Inv y EECC (UPIC), Madrid, Not set

Many Locations, Multiple Locations, Not set

Hospital Regional de Málaga, Málaga, Not set

Virgen del Rocio University Hospital | Pediatric Nephrology Unit, Sevilla, Not set

Skåne University Hospital, Lund, Not set

Many Locations, Multiple Locations, Not set

Karolinska University Hospital, Stockholm, Not set

Uppsala University Hospital, Uppsala, Not set

Universitäts-Kinderspital UKBB, Basel, Basel-Stadt

Centre Hospitalier Universitaire Vaudois (CHUV), Lausanne, Vaud

Hopital des Enfants HUG, Geneva, Not set

Many Locations, Multiple Locations, Not set

Cukurova Univ. Tip. Fak. Balcali Hastanesi, Adana, Not set

Hacettepe Universitesi Tip Fakultesi, Ankara, Not set

Baskent Universitesi Tip Fakultesi Hastanesi, Ankara, Not set

Gazi Universitesi Tip Fakultesi, Ankara, Not set

Health Ministry Of Türkiye Republic Ankara Bilkent City Hospital, Ankara, Not set

Istanbul Faculty of Medicine, Department of Internal Medicine, Department of Pediatrics, Istanbul, Not set

Istanbul Universitesi Cerrahpasa-Cocuk Nefrolojisi B. Dali, Istanbul, Not set

Marmara Uni. Tip Fakultesi Pendik Egitim ve Aras. Hastanesi, Istanbul, Not set

Many Locations, Multiple Locations, Not set

Birmingham Children's Hospital, Birmingham, West Midlands

Royal Hospital for Children, Glasgow, Not set

Great Ormond Street Hospital for Children, London, Not set

Royal Manchester Children's Hospital, Manchester, Not set

Many Locations, Multiple Locations, Not set

Queens Medical Centre, Nottingham, Not set

Conditions: Chronic Kidney Disease, Proteinuria

Learn More ›

Multicultural Healthy Diet in Chronic Kidney Disease

NCT05504850

Recruiting

This is a pilot intervention study to evaluate the feasibility and acceptability of a culturally-tailored anti-inflammatory diet intervention in participants with chronic kidney disease.

Gender:

All

Ages:

Between 18 years and 85 years

Trial Updated:

05/15/2024

Locations: Montefiore Medical Center, Bronx, New York

Conditions: Chronic Kidney Disease

Learn More ›

University of Michigan "Nephrology Research BioBank"

NCT00381121

Recruiting

The purpose of the study is to create a Nephrology Tissue Biobank enabling the study of kidney disease from the perspectives of epidemiology, genetics and molecular biology.

Gender:

All

Ages:

All

Trial Updated:

05/10/2024

Locations: University of Michigan Health System, Ann Arbor, Michigan

Conditions: Chronic Kidney Disease

Learn More ›

Proteogenomic Monitoring and Assessment of Liver Transplant Recipients

NCT01644903

Recruiting

This study is being done to test blood, urine and tissue samples to see if this can help decide if CKD (Chronic Kidney Disease), AR (Acute Rejection) and HCV (Hepatitis C Virus) can be identified in its early stages. CKD damage to the kidneys, AR and HCV all lower the body's ability to function properly. Early detection of these conditions could assist with successful treatment and possibly lead to less repeat organ transplants.

Gender:

All

Ages:

18 years and above

Trial Updated:

04/24/2024

Locations: Northwestern Memorial Hospital, Chicago, Illinois

Conditions: Liver Transplant, Hepatitis C, Chronic Kidney Disease, Acute Rejection

Learn More ›

Efficacy and Safety of Lorundrostat Alone, and in Combination With Dapagliflozin in Subjects With Hypertension and Chronic Kidney Disease (CKD) With Albuminuria

NCT06150924

Recruiting

This is a 2-part study evaluating the efficacy and safety of lorundrostat (an aldosterone synthase inhibitor [ASI]) for the treatment of hypertension in subjects with CKD and albuminuria while receiving stable treatment with an angiotensin converting enzyme inhibitor (ACEi) or an angiotensin receptor blocker (ARB) either in combination with dapagliflozin, or alone.

Gender:

All

Ages:

18 years and above

Trial Updated:

04/24/2024

Locations: Arizona Kidney Disease & Hypertension Centers (AKDHC) - Thunderbird Office, Glendale, Arizona +28 locations

Arizona Kidney Disease & Hypertension Centers (AKDHC) - Thunderbird Office, Glendale, Arizona

Arizona Kidney Disease & Hypertension Centers (AKDHC) - Thomas Office, Phoenix, Arizona

Balboa Nephrology Medical Group, Inc. (BNMG) - California Institute of Renal Research (CIRR) - Chula Vista, Chula Vista, California

Balboa Nephrology Medical Group, Inc. (BNMG) - El Centro, El Centro, California

Academic Medical Research Institute (AMRI) - Los Angeles, Los Angeles, California

Qway Research, Coconut Grove, Florida

Elixia Pines, LLC, Hollywood, Florida

Elixia Central Florida, LLC, Orlando, Florida

Genesis Clinical Research - Tampa, Tampa, Florida

Palm Beach Diabetes and Endocrine Specialists, PA (PBDES) - West Palm Beach Office, West Palm Beach, Florida

Nephrology of the Golden Isles - Brunswick, Brunswick, Georgia

ClinCept, LLC, Columbus, Georgia

Nephrology Associates of Kentuckiana, PSC (NAK), Louisville, Kentucky

Northwest Louisiana Nephrology, Llc - Shreveport, Shreveport, Louisiana

Tufts University School of Medicine (Tusm) - Tufts Medical Center (Tmc) (Tufts-New England Medical Center), Boston, Massachusetts

Elixia MKC, LLC, Pontiac, Michigan

Kansas City Kidney Consultants (Arms, Dodge, Robinson, Wilber & Crouch, Inc.) - Kansas City, Kansas City, Missouri

Seacoast Kidney & Hypertension Specialists - Portsmouth Office, Portsmouth, New Hampshire

Nephrology Associates, PC, Fresh Meadows, New York

Nephrology Associates, Fresh Meadows, New York

Triad Internal Medicine, Asheboro, North Carolina

Nephrology Associates, Pllc - Winston-Salem, Winston-Salem, North Carolina

Southeast Renal Research Institute, Chattanooga, Tennessee

Dallas Nephrology Associates (Dna) - Renal Disease Research Institute (Rdri), Dallas, Texas

R&H Clinical Research, Katy, Texas

E T Nephrology Associates - Lufkin, Lufkin, Texas

Gamma Medical Research, Inc, Mission, Texas

Chrysalis Clinical Research (CCR), Saint George, Utah

Mendez Center for Clinical Research, LLC, Woodbridge, Virginia

Conditions: Chronic Kidney Disease

Learn More ›

Trial to Evaluate and Assess the Effect of Comprehensive Pre-ESKD Education on Home Dialysis Use in Veterans

NCT04064086

Recruiting

This study is intended to correct an important systemic deficit in the care of chronic kidney disease (CKD), VHA's fourth most common healthcare condition with high mortality and healthcare burden. Currently, many Veterans with CKD have poor awareness of their condition. This leads to suboptimal care. The investigators anticipate that the proposed comprehensive pre-end stage renal disease (ESRD) education (CPE) will enhance Veterans' CKD knowledge and their confidence in making an informed selec... Read More

Gender:

All

Ages:

18 years and above

Trial Updated:

02/22/2024

Locations: North Florida/South Georgia Veterans Health System, Gainesville, FL, Gainesville, Florida

Conditions: Chronic Kidney Disease, End Stage Renal Disease, Hemodialysis, Peritoneal Dialysis

Learn More ›

L-arginine to Reduce Sympathetic Nerve Activity in CKD Patients

NCT03982160

Recruiting

Chronic kidney disease (CKD) is associated with a higher risk of cardiovascular disease and death. An overactive sympathetic nervous system in CKD patients is one of the major mechanisms increasing the cardiovascular risks in this patient population. A potential signal driving sympathetic nerve activity (SNA) involves accumulation of the endogenous nitric oxide synthase (NOS) inhibitor asymmetric dimethylarginine (ADMA). ADMA is elevated in CKD and is a strong, independent predictor of future ca... Read More

Gender:

All

Ages:

Between 35 years and 75 years

Trial Updated:

01/14/2024

Locations: University of Delaware, Newark, Delaware +1 locations

Conditions: Chronic Kidney Disease

Learn More ›

Transforming Hemodialysis-Related Vascular Access Education

NCT05997875

Recruiting

The focus of this study is on vascular access for hemodialysis. This is a randomized clinical trial testing 3 educational approaches to help patients with advanced chronic kidney disease prepare for placement of hemodialysis vascular access. Study participants will each be assigned to one of the 3 approaches: 1) "Education", in which participants will be given a video and brochure that provide information about the types of vascular access and what can be expected before and after the vascular a... Read More

Gender:

All

Ages:

18 years and above

Trial Updated:

01/05/2024

Locations: University of North Carolina at Chapel Hill, Chapel Hill, North Carolina +1 locations

Conditions: Chronic Kidney Disease, Hemodialysis Vascular Access

Learn More ›

Diuretics and Volume Overload in Early CKD

NCT05171686

Recruiting

Almost 15% of Americans have chronic kidney disease (CKD), with an even higher rate in Veterans due to common risk factors such as high blood pressure and diabetes. People with CKD have a high risk of cardiovascular (CV) diseases, such as heart attacks, heart failure, and strokes. Extra fluid in the body, called volume overload, may lead to CV disease in people with CKD. It is unknown if volume overload develops in the earliest stages of CKD, when treating it with common, inexpensive medicines c... Read More

Gender:

All

Ages:

18 years and above

Trial Updated:

01/03/2024

Locations: Michael E. DeBakey VA Medical Center, Houston, TX, Houston, Texas

Conditions: Chronic Kidney Disease, Hypertension

Learn More ›

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