There are currently 33 active clinical trials seeking participants for Chronic Kidney Disease research studies. The states with the highest number of trials for Autism participants are California, Texas, Florida and New York.
A Study of Daily Oral Orforglipron (LY3502970) Compared With Insulin Glargine in Participants With Type 2 Diabetes and Obesity or Overweight at Increased Cardiovascular Risk
NCT05803421
Recruiting
The main purpose of this study is to determine safety and efficacy of orforglipron compared with insulin glargine in participants with type 2 diabetes and obesity or overweight at increased cardiovascular risk. The study will last approximately 2 years may include up to 27 visits.
Gender:
All
Ages:
18 years and above
Trial Updated:
03/12/2024
Locations: Alliance for Multispecialty Research, LLC, Daphne, Alabama +388 locations
Conditions: Type 2 Diabetes, Obesity, Overweight or Obesity, Overweight, Cardiovascular Diseases, Chronic Kidney Disease
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Trial to Evaluate and Assess the Effect of Comprehensive Pre-ESKD Education on Home Dialysis Use in Veterans
NCT04064086
Recruiting
This study is intended to correct an important systemic deficit in the care of chronic kidney disease (CKD), VHA's fourth most common healthcare condition with high mortality and healthcare burden. Currently, many Veterans with CKD have poor awareness of their condition. This leads to suboptimal care. The investigators anticipate that the proposed comprehensive pre-end stage renal disease (ESRD) education (CPE) will enhance Veterans' CKD knowledge and their confidence in making an informed selec... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
02/22/2024
Locations: North Florida/South Georgia Veterans Health System, Gainesville, FL, Gainesville, Florida
Conditions: Chronic Kidney Disease, End Stage Renal Disease, Hemodialysis, Peritoneal Dialysis
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Effects of Constipation Treatment in Chronic Kidney Disease: A Pilot Feasibility Trial
NCT06123195
Recruiting
Constipation is one of the most prevalent gastrointestinal disorders in patients with chronic kidney disease (CKD) and has been associated with their adverse kidney and cardiovascular outcomes; however, little is known about the effects of constipation treatment on clinical outcomes nor on outcome-related biochemical and microbiological parameters in patients with CKD. The investigators aim to test the feasibility of delivering an intervention with constipation treatment and determine its effect... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
02/12/2024
Locations: Memphis VA Medical Center, Memphis, Tennessee
Conditions: Chronic Kidney Disease, Constipation
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ARTEMIS: Ravulizumab to Protect Patients With CKD From CSA-AKI and MAKE
NCT05746559
Recruiting
The primary objective of this study is to assess the efficacy of a single dose of ravulizumab IV compared with placebo in reducing the risk of the clinical consequences of AKI (MAKE) at 90 days in adult participants with CKD who undergo non-emergent cardiac surgery with CPB.
Gender:
All
Ages:
Between 18 years and 90 years
Trial Updated:
02/06/2024
Locations: Research Site, San Francisco, California +159 locations
Conditions: Chronic Kidney Disease, CKD, Cardiac Disease, Cardiopulmonary Bypass
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L-arginine to Reduce Sympathetic Nerve Activity in CKD Patients
NCT03982160
Recruiting
Chronic kidney disease (CKD) is associated with a higher risk of cardiovascular disease and death. An overactive sympathetic nervous system in CKD patients is one of the major mechanisms increasing the cardiovascular risks in this patient population. A potential signal driving sympathetic nerve activity (SNA) involves accumulation of the endogenous nitric oxide synthase (NOS) inhibitor asymmetric dimethylarginine (ADMA). ADMA is elevated in CKD and is a strong, independent predictor of future ca... Read More
Gender:
All
Ages:
Between 35 years and 75 years
Trial Updated:
01/14/2024
Locations: University of Delaware, Newark, Delaware +1 locations
Conditions: Chronic Kidney Disease
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Transforming Hemodialysis-Related Vascular Access Education
NCT05997875
Recruiting
The focus of this study is on vascular access for hemodialysis. This is a randomized clinical trial testing 3 educational approaches to help patients with advanced chronic kidney disease prepare for placement of hemodialysis vascular access. Study participants will each be assigned to one of the 3 approaches: 1) "Education", in which participants will be given a video and brochure that provide information about the types of vascular access and what can be expected before and after the vascular a... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
01/05/2024
Locations: University of North Carolina at Chapel Hill, Chapel Hill, North Carolina +1 locations
Conditions: Chronic Kidney Disease, Hemodialysis Vascular Access
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Diuretics and Volume Overload in Early CKD
NCT05171686
Recruiting
Almost 15% of Americans have chronic kidney disease (CKD), with an even higher rate in Veterans due to common risk factors such as high blood pressure and diabetes. People with CKD have a high risk of cardiovascular (CV) diseases, such as heart attacks, heart failure, and strokes. Extra fluid in the body, called volume overload, may lead to CV disease in people with CKD. It is unknown if volume overload develops in the earliest stages of CKD, when treating it with common, inexpensive medicines c... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
01/03/2024
Locations: Michael E. DeBakey VA Medical Center, Houston, TX, Houston, Texas
Conditions: Chronic Kidney Disease, Hypertension
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University of Michigan "Nephrology Research BioBank"
NCT00381121
Recruiting
The purpose of the study is to create a Nephrology Tissue Biobank enabling the study of kidney disease from the perspectives of epidemiology, genetics and molecular biology.
Gender:
All
Ages:
All
Trial Updated:
01/03/2024
Locations: University of Michigan Health System, Ann Arbor, Michigan
Conditions: Chronic Kidney Disease
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Patient-driven Management of BP in CKD
NCT05546099
Recruiting
The proposed research will evaluate if patients managing their blood pressure medications under the guidance of a clinical pharmacist works better to lower blood pressure than patients monitoring their blood pressure at home and the standard care. 60 Veterans with chronic kidney disease (CKD) will be included in the study. The study will further evaluate factors that may influence the Veteran to accept the self-management approach and what factors in the VHA healthcare system affect the implemen... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
12/05/2023
Locations: Iowa City VA Health Care System, Iowa City, IA, Iowa City, Iowa
Conditions: Chronic Kidney Disease
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Benefit of Transradial Approach in Chronic Kidney Disease Population Undergoing Cardiac Catheterization
NCT02933892
Recruiting
The investigators will conduct a randomized controlled trial that aims to compare the incidence of contrast-induced nephropathy between transradial- and transfemoral-access cardiac catheterization.
Gender:
All
Ages:
Between 18 years and 88 years
Trial Updated:
11/28/2023
Locations: Texas Tech University Health Sciences Center, Lubbock, Texas
Conditions: Chronic Kidney Disease, Acute Kidney Injury, Heart Disease
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Multicultural Healthy Diet in Chronic Kidney Disease
NCT05504850
Recruiting
This is a pilot intervention study to evaluate the feasibility and acceptability of a culturally-tailored anti-inflammatory diet intervention in participants with chronic kidney disease.
Gender:
All
Ages:
Between 18 years and 85 years
Trial Updated:
09/26/2023
Locations: Montefiore Medical Center, Bronx, New York
Conditions: Chronic Kidney Disease
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Clinical Phenotyping Resource and Biobank Core of the Michigan O'Brien Renal Center
NCT01016613
Recruiting
Chronic kidney disease (CKD) affects approximately 26 million Americans and disproportionately manifests in specific race and ethnic groups. Patients burdened with CKD have significant morbidity and reduced life expectancy. In addition to excessive suffering and lost productivity, the cost of managing this epidemic has reached $40 billion annually. The recognition that CKD is a major public health problem is reflected in the fourteen objectives outlined in Healthy People 2020 to begin to address... Read More
Gender:
All
Ages:
All
Trial Updated:
09/18/2023
Locations: University of Michigan Health System, Ann Arbor, Michigan +4 locations
Conditions: Chronic Kidney Disease, Glomerulopathy
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