There are currently 33 active clinical trials seeking participants for Chronic Kidney Disease research studies. The states with the highest number of trials for Chronic Kidney Disease participants are California, Texas, Florida and New York.
A Study to Learn About How Well BAY3283142 Works and Its Safety in Participants With Chronic Kidney Disease
Recruiting
Researchers are looking for a better way to treat people who have chronic kidney disease (CKD), CKD is a condition in which the kidneys' ability to work properly gradually decreases over time. A common sign of decreasing kidney function is the body losing too much of a protein called albumin in the urine. This condition is known as albuminuria. This can lead to a faster decline in kidney function. People who have high blood pressure and diabetes are more likely to have CKD and are at a higher ri... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
04/10/2025
Locations: Nephrology Consultants, LLC, Huntsville, Alabama +169 locations
Conditions: Chronic Kidney Disease
A Phase 1b Study to Assess the Safety, Tolerability, and Pharmacodynamics of AZD4144 in Participants With Established Atherosclerotic Cardiovascular and Chronic Kidney Disease.
Recruiting
The purpose of this study is to evaluate the safety, tolerability and the pharmacodynamics (PD) of AZD4144 following oral administration in participants with atherosclerotic cardiovascular disease (ASCVD) and chronic kidney disease (CKD).
Gender:
ALL
Ages:
Between 18 years and 80 years
Trial Updated:
04/09/2025
Locations: Research Site, Glendale, California +18 locations
Conditions: Chronic Kidney Disease, Atherosclerotic Cardiovascular Disease
A Natural History Study of Metabolic Sizing in Health and Disease
Recruiting
Background: Scientists have long used simple measures (such as height and weight) to estimate how much a person s body uses food (calories) as energy, as commonly called the metabolic rate. But metabolism varies among people with similar body sizes. Scientists now believe the old formulas for estimating metabolic rates may not work well for all people. Researchers want to find more accurate ways to measure a person s metabolism. Objective: This natural history study will examine the relations... Read More
Gender:
ALL
Ages:
Between 2 years and 99 years
Trial Updated:
03/25/2025
Locations: National Institutes of Health Clinical Center, Bethesda, Maryland
Conditions: Metabolic Disorders, Cancer, Chronic Kidney Disease, Diabetes, Normal Physiology
A Research Study to See if Kidney Damage in People With Chronic Kidney Disease and Type 2 Diabetes Living With Overweight or Obesity Can be Reduced by CagriSema Compared to Semaglutide, Cagrilintide and Placebo
Recruiting
This study will look if CagriSema can lower kidney damage in people with chronic kidney disease (CKD), type 2 diabetes (T2D) and overweight or obesity. CagriSema is a new investigational medicine. CagriSema cannot yet be prescribed by doctors. The study will compare CagriSema to the 2 medicines semaglutide and cagrilintide, when they are taken alone. It will also compare CagriSema to a "dummy" medicine (also called placebo) without any active ingredient. Participant will either get CagriSema, se... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
03/18/2025
Locations: John Muir Physicians Network, Concord, California +139 locations
Conditions: Chronic Kidney Disease, Type 2 Diabetes, Obesity
Sympatholysis in Chronic Kidney Disease
Recruiting
The purpose of this study is to find out why patients with chronic kidney disease (CKD) have poor exercise capacity and what causes an increase in blood pressure during exercise (i.e. increased adrenaline levels, or decreased ability of blood vessels to dilate).
Gender:
ALL
Ages:
Between 18 years and 75 years
Trial Updated:
03/03/2025
Locations: Atlanta VA Medical Center, Decatur, Georgia
Conditions: Chronic Kidney Disease
L-arginine to Reduce Sympathetic Nerve Activity in CKD Patients
Recruiting
Chronic kidney disease (CKD) is associated with a higher risk of cardiovascular disease and death. An overactive sympathetic nervous system in CKD patients is one of the major mechanisms increasing the cardiovascular risks in this patient population. A potential signal driving sympathetic nerve activity (SNA) involves accumulation of the endogenous nitric oxide synthase (NOS) inhibitor asymmetric dimethylarginine (ADMA). ADMA is elevated in CKD and is a strong, independent predictor of future ca... Read More
Gender:
ALL
Ages:
Between 35 years and 75 years
Trial Updated:
02/28/2025
Locations: University of Delaware, Newark, Delaware +1 locations
Conditions: Chronic Kidney Disease
Prevalence of Gastric Motor Dysfunction and Upper GI Symptoms in Gastric Antral Vascular Ectasias
Recruiting
The researchers are trying to find out more about Gastric Antral Vascular Ectasia (GAVE). This is a condition that affects the blood vessels in the stomach, leading to their enlargement and possible bleeding. It can also cause symptoms such as abdominal pain and nausea. By participating in this study, you will help us learn how often these symptoms occur and how they relate to stomach functioning.
Gender:
ALL
Ages:
19 years and above
Trial Updated:
02/13/2025
Locations: Mayo Clinic, Rochester, Minnesota
Conditions: Gastric Antral Vascular Ectasia, Cirrhosis, Chronic Kidney Disease
Trial to Evaluate and Assess the Effect of Comprehensive Pre-ESKD Education on Home Dialysis Use in Veterans
Recruiting
This study is intended to correct an important systemic deficit in the care of chronic kidney disease (CKD), VHA's fourth most common healthcare condition with high mortality and healthcare burden. Currently, many Veterans with CKD have poor awareness of their condition. This leads to suboptimal care. The investigators anticipate that the proposed comprehensive pre-end stage renal disease (ESRD) education (CPE) will enhance Veterans' CKD knowledge and their confidence in making an informed selec... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
02/05/2025
Locations: North Florida/South Georgia Veterans Health System, Gainesville, FL, Gainesville, Florida
Conditions: Chronic Kidney Disease, End Stage Renal Disease, Hemodialysis, Peritoneal Dialysis
A Stakeholder-enhanced Intervention to Improve the Decisional Partnership of Chronic Kidney Disease Dyads (IMPART)
Recruiting
Using a highly innovative methodology, the Multiphase Optimization Strategy (MOST), the purpose of this study is to pilot test, an optimization trial approach to develop and refine the decision partnering skills of persons with stage 4 chronic kidney disease and their caregivers. Using a 2x2x2 full factorial design, 64 dyads (patients and one identified caregiver) will be randomized to receive one or more lay coach-delivered decision partnering training components, based on Pearlin's Stress-Heal... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
01/29/2025
Locations: Shena Gazaway, Birmingham, Alabama
Conditions: Decision Making, Shared, Family Caregiving, Chronic Kidney Disease
Transforming Hemodialysis-Related Vascular Access Education
Recruiting
The focus of this study is on vascular access for hemodialysis. This is a randomized clinical trial testing 3 educational approaches to help patients with advanced chronic kidney disease prepare for placement of hemodialysis vascular access. Study participants will each be assigned to one of the 3 approaches: 1) "Education", in which participants will be given a video and brochure that provide information about the types of vascular access and what can be expected before and after the vascular a... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
01/08/2025
Locations: University of North Carolina at Chapel Hill, Chapel Hill, North Carolina +1 locations
Conditions: Chronic Kidney Disease, Hemodialysis Vascular Access
Intensive Patient Referral and Education Program Prior to Renal Replacement Therapy
Recruiting
Intensive Patient Referral and Education Program prior to Renal Replacement Therapy (iPREP-RRT) is a 12-week intervention that identifies hospitalized African Americans with advanced chronic kidney disease (CKD) and provides them with hospital- and community-based education, navigation and self-management support. Participants will be randomized to the iPREP-RRT intervention versus enhanced usual care.
Gender:
ALL
Ages:
Between 18 years and 70 years
Trial Updated:
01/07/2025
Locations: University of Chicago Medical Center, Chicago, Illinois
Conditions: Chronic Kidney Disease, Hypertension
Diuretics and Volume Overload in Early CKD
Recruiting
Almost 15% of Americans have chronic kidney disease (CKD), with an even higher rate in Veterans due to common risk factors such as high blood pressure and diabetes. People with CKD have a high risk of cardiovascular (CV) diseases, such as heart attacks, heart failure, and strokes. Extra fluid in the body, called volume overload, may lead to CV disease in people with CKD. It is unknown if volume overload develops in the earliest stages of CKD, when treating it with common, inexpensive medicines c... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
12/05/2024
Locations: Michael E. DeBakey VA Medical Center, Houston, TX, Houston, Texas
Conditions: Chronic Kidney Disease, Hypertension