There are currently 44 active clinical trials seeking participants for Cognitive Decline research studies. The states with the highest number of trials for Cognitive Decline participants are Illinois, Michigan, Minnesota and California.
Glucose Variability and Cognition in Prediabetes
NCT04201600
Recruiting
This study examines the association of variability in glucose values over a 10-day period with cognitive function and functional status among individuals with prediabetes, aged 50 or older.
Gender:
All
Ages:
50 years and above
Trial Updated:
05/14/2024
Locations: Baltimore VA Geriatric Research Education and Clinical Center (GRECC), Baltimore, Maryland
Conditions: Glucose Metabolism Disorders (Including Diabetes Mellitus), Cognitive Decline, Functional Status, PreDiabetes, Aging, Depression
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Cognitive Screening Made Easy for PCPs - R33 Phase
NCT06162026
Recruiting
This project will facilitate early detection of cognitive decline in older adults through development and implementation of an automated risk assessment and cognitive screening tool for use in primary care. By providing an automated tool developed specifically to address the needs of PCPs, it will be easier to screen for cognitive impairment, increasing the number of older adults who are screened and thus identified and treated.
Gender:
All
Ages:
60 years and above
Trial Updated:
04/23/2024
Locations: Family Wellness Clinic, Austin, Texas
Conditions: Cognitive Impairment, Dementia, Mild, Cognitive Decline
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Brain Health in Youth With Normal Weight, Overweight and Obesity at Risk for Type 2 Diabetes (T2D)
NCT05277558
Recruiting
Investigators propose to study youth across the spectrum of body mass index (BMI) and dysglycemia. This approach will allow investigators to disentangle the relationship of key features of type 2 diabetes (T2D) risk (e.g. obesity) with intermediary physiologic changes (e.g. insulin resistance, inflammation, β-cell dysfunction and dysglycemia) that pose a risk for the brain. Investigators will determine which of these factors are most associated with differences in brain structure and function am... Read More
Gender:
All
Ages:
Between 12 years and 17 years
Trial Updated:
04/10/2024
Locations: Washington University School of Medicine, Saint Louis, Missouri +1 locations
Conditions: Type2 Diabetes, Type 2 Diabetes Mellitus in Obese, Dysglycemia, Microvascular Complications, Brain Structure, Obesity, Childhood, Diabetes in Adolescence, Inflammation, Insulin Resistance, Overweight, Childhood, Cognitive Decline
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The Impact of Goode Health Beverage on Markers of Physiological and Neurocognitive Health
NCT06245382
Recruiting
The overall research objective of this proposal is to determine the acute and chronic impact of daily supplementation of a Good Health beverage on indices of physiological and neurocognitive health.
Gender:
All
Ages:
Between 18 years and 55 years
Trial Updated:
03/12/2024
Locations: UT Arlington - Science and Engineering Innovation and Research Building, Arlington, Texas +1 locations
Conditions: Cardiovascular Diseases, Hypertension, Cognitive Decline, Diet, Healthy
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Cognitive and Vascular Functioning Following TBI
NCT06034509
Recruiting
This observational study will examine the association of chronic traumatic cerebrovascular injury and cardiovascular risk factors with TBI-related cognitive impairment and vascular dementia. Cerebrovascular, inflammatory, and neurodegenerative blood biomarkers as well as clinical and neuroimaging data
Gender:
All
Ages:
Between 18 years and 74 years
Trial Updated:
12/06/2023
Locations: Walter Reed National Military Medical Center, Bethesda, Maryland
Conditions: Traumatic Brain Injury, Cognitive Decline, Vascular Dementia
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Cognitive Impairment in Colorectal Cancer Patients Receiving Cytotoxic Chemotherapy
NCT05014399
Recruiting
The purpose of this research study is to see how the brain changes in patients receiving chemotherapy (cytotoxic drug) treatment for colon or rectal cancer at Parkview Cancer Institute. This information will be used to identify helpful tests to diagnose individuals at risk for developing difficulties with thinking and memory due to their cancer treatments.
Gender:
All
Ages:
18 years and above
Trial Updated:
11/14/2023
Locations: Parkview Cancer Institute, Fort Wayne, Indiana
Conditions: Neoplasm, Colorectal, Cognitive Impairment, Cognitive Dysfunction, Cognitive Change, Chemo-brain, Chemo Fog, Chemotherapy Effect, Cognitive Decline
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Computerized Tests of Cognitive Decline in Presymptomatic Alzheimer's Disease
NCT04800588
Recruiting
The investigators will study performance on computerized cognitive tasks in healthy participants of different ages to gather normative data for newly developed computerized cognitive tests. These tests are designed to permit the early detection of individuals at risk of age-related cognitive decline.
Gender:
All
Ages:
Between 18 years and 89 years
Trial Updated:
03/22/2023
Locations: Neurobehavioral Systems, Inc., Berkeley, California
Conditions: Alzheimer Disease, Aging, Cognitive Decline
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Modulation Effects of Baduanjin Exercise on Subjective Cognitive Decline
NCT04009382
Recruiting
The aim of this study is to investigate the modulation effects of Baduanjin (BDJ), a simple and innovative mind-body exercise, on cognitive function, resting state functional connectivity, and brain morphometry in individuals with subjective cognitive decline (SCD). The results obtained will provide novel insights for improving the prevention of age-related cognitive decline and Alzheimer's disease.
Gender:
All
Ages:
Between 50 years and 80 years
Trial Updated:
12/29/2022
Locations: Massachusetts General Hospital, Charlestown, Massachusetts
Conditions: Cognitive Decline
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