There are currently 16 active clinical trials seeking participants for Constipation research studies. The states with the highest number of trials for Autism participants are Florida, California, Texas and North Carolina.
Effects of Constipation Treatment in Chronic Kidney Disease: A Pilot Feasibility Trial
Recruiting
Constipation is one of the most prevalent gastrointestinal disorders in patients with chronic kidney disease (CKD) and has been associated with their adverse kidney and cardiovascular outcomes; however, little is known about the effects of constipation treatment on clinical outcomes nor on outcome-related biochemical and microbiological parameters in patients with CKD. The investigators aim to test the feasibility of delivering an intervention with constipation treatment and determine its effect... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
02/12/2024
Locations: Memphis VA Medical Center, Memphis, Tennessee
Conditions: Chronic Kidney Disease, Constipation
Effect of L. Paracasei Strain Shirota on Constipation in Healthy US Adults
Recruiting
The objective of this study is to investigate the efficacy of daily consumption of a fermented milk containing LcS in reducing the frequency of bowel movement with hard or lumpy stools in generally healthy U.S. adult population with intermittent bowel movements producing hard or lumpy stools.
Gender:
All
Ages:
Between 18 years and 64 years
Trial Updated:
12/27/2023
Locations: Biofortis, Chicago, Illinois
Conditions: Constipation
Preop Laxatives in Robotic Urologic Surgery
Recruiting
Minimally-invasive surgery, either laparoscopic or robotic, is commonly used in urology. Several urologic procedures including prostatectomy, radical nephrectomy, and partial nephrectomy are now commonly performed robotically. Patients undergoing these procedures often have delayed return of bowel function and persistent gastrointestinal symptoms including nausea/vomiting, abdominal distension, and bloating for several days to weeks after surgery. Postoperative stool softeners and laxatives are... Read More
Gender:
All
Ages:
Between 30 years and 100 years
Trial Updated:
12/22/2023
Locations: University of Iowa Hospitals & Clinics, Iowa City, Iowa
Conditions: Prostate Cancer, Kidney Cancer, Constipation
Fecobionics in Biofeedback Therapy in Dyssynergia Patients
Recruiting
Constipation affects 12-19% of Americans. Pelvic floor dyssynergia is considered to play an important role in constipation but the underlying mechanisms are not well understood in individual patients. The investigators have developed a novel device named Fecobionics that provide detailed mapping of physiological parameters during defecation. The aim of the study is to use Fecobionics to assess anorectal function in dyssynergia patients and monitor and predict the outcome of the biofeedback thera... Read More
Gender:
All
Ages:
Between 21 years and 75 years
Trial Updated:
12/04/2023
Locations: California Medical Innovations Institute, San Diego, California
Conditions: Dyssynergia, Constipation
Evaluation of Fecal Microbiome Changes After Antegrade Continence Enema Placement and Initiation of Bowel Flush Regimen
Recruiting
This study will evaluate changes in the fecal microbiome in constipated pediatric patients before and after antegrade continence enema placement and initiation of antegrade enema flushes. Subjects will have their microbiome sequenced prior to placement by obtaining a fecal sample. Pre-antegrade continence enema placement results will be compared to fecal samples obtained at 0, 4, 8 months after placement of the antegrade continence enema and initiation of miralax or golytely flushes to look for... Read More
Gender:
All
Ages:
Between 2 years and 21 years
Trial Updated:
11/10/2023
Locations: IU North Hospital, Carmel, Indiana +1 locations
Conditions: Constipation
Effect of Osteopathic Manipulative Medicine on Constipation in Parkinson's Disease
Recruiting
The aim of this pilot study is to investigate the effect of Osteopathic Manipulative Medicine (OMM) in decreasing constipation symptoms in people with Parkinson's disease (PD). A second but optional aim is to determine if OMM changes the bacterial flora of the mouth and gut. OMM is a safe and gentle manual treatment provided by osteopathic physicians. All participants will receive OMM during the second half of the eleven week trial.
Gender:
All
Ages:
40 years and above
Trial Updated:
11/08/2023
Locations: New York Institute of Technology- Academic Health Care Center, Old Westbury, New York
Conditions: Parkinson's Disease, Constipation
A Clinical Trial to Evaluate the Effect of ConcenTrace Trace Mineral Drops on Gut Health
Recruiting
This is a virtual single-arm trial that will last 12 weeks. Participants will take the drops daily and complete questionnaires at Baseline, Week 4, Week 8, and Week 12. Gut health, bowel movements, stool looseness, constipation, bloating, and regularity will be evaluated at the Baseline and at each check-in. Likert scale responses will be statistically compared from Baseline to each check-in. Participant responses and product feedback will be presented as percentage scores.
Gender:
All
Ages:
18 years and above
Trial Updated:
11/02/2023
Locations: Citruslabs, Santa Monica, California
Conditions: Gut Health, Bowel Movements, Constipation, Bloating
Use of a Squatting Assist Device in Patients With Constipation
Recruiting
Constipation is a very common problem. Western style toilets that are nearly universal in the United States require the person to sit on the toilet. However, results from uncontrolled studies suggests that a squatting posture (as prevalent in many foreign countries) may be better at facilitating evacuation compared to a Western style commode. One uncontrolled, unpublished study suggests that a footstool improved bowel symptoms in nearly 98% of 153 constipated participants. Hence, the investigato... Read More
Gender:
Female
Ages:
Between 18 years and 80 years
Trial Updated:
09/28/2023
Locations: Mayo Clinic in Rochester, Rochester, Minnesota
Conditions: Constipation
Understanding Mechanisms of Normal and Disordered Defecation
Recruiting
Researchers are trying to better understand why constipation occurs and improve the tests for diagnosing these conditions.
Gender:
All
Ages:
Between 18 years and 80 years
Trial Updated:
09/26/2023
Locations: Mayo Clinic in Rochester, Rochester, Minnesota
Conditions: Constipation
Bowel Function After Minimally Invasive Hysterectomy
Recruiting
Postoperative constipation affects up to a third of women undergoing minimally invasive (MIS) gynecologic surgery and is a major source of anxiety and discomfort. The average time to first bowel movement after gynecologic surgery is about 2 to 4 days and some factors responsible for this include anesthesia inhibitory effect on gastrointestinal motility, opioid pain medication use, chronic NSAID use and anatomic manipulation. There are no established regimens to manage postoperative constipation... Read More
Gender:
Female
Ages:
18 years and above
Trial Updated:
07/17/2023
Locations: University of Chicago Medicine, Chicago, Illinois
Conditions: Constipation
Pyridostigmine for the Treatment of Constipation in Parkinson Disease
Recruiting
Constipation is a common and debilitating non-motor symptom of Parkinson disease (PD) that often precedes the onset of classic motor symptoms by decades. There is no standardized algorithm for managing constipation in this patient population, nor are there dedicated treatments. Studies suggest that constipation can affect quality of life to a significant degree, in many cases just as much as motor symptoms. There is an unmet need for effective treatment options for constipation in this patient p... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
06/15/2023
Locations: University of Vermont Medical Center, Burlington, Vermont
Conditions: Parkinson Disease, Constipation
The Impact of Respiratory Muscle Training and Patient Education on Chronic Constipation Outcomes
Recruiting
The primary aim of this study will be to determine if a respiratory muscle training program that includes both inspiratory muscle training (IMT) and expiratory muscle training (EMT), targeted at improving respiratory muscle performance-based measures combined with patient education about breathing on the toilet will improve patient satisfaction scores in individuals with chronic constipation (CC).
Gender:
All
Ages:
18 years and above
Trial Updated:
06/08/2023
Locations: University of Miami, Coral Gables, Florida
Conditions: Constipation, Constipation - Functional, Dyssynergia