There are currently 42 active clinical trials seeking participants for Critical Illness research studies. The states with the highest number of trials for Autism participants are Ontario, Victoria, Alberta and Ohio.
RCT: Early Feeding After PEG Placement
Recruiting
Randomized controlled trial to establish evidence on which to base timing of enteral feeding after bedside PEG placement in ventilated Trauma and Surgical ICU patients.
Gender:
All
Ages:
Between 18 years and 100 years
Trial Updated:
10/18/2021
Locations: Carilion Roanoke Memorial Hospital, Roanoke, Virginia
Conditions: Critical Illness, Malnutrition, Gastrostomy, Procedural Sequelae, Trauma, Surgery, Mechanical Ventilation
Anticipating Decline and Providing Therapy
Recruiting
This pilot feasibility study will be a randomized control trial of usual care following Intensive Care Unit (ICU) discharge compared to the Anticipating Decline and Providing Therapy (ADAPT) screening and support intervention. The trial aims to enroll 120 older adults (age 60 or older).
Gender:
All
Ages:
60 years and above
Trial Updated:
03/21/2024
Locations: Atrium Health Wake Forest Baptist, Winston-Salem, North Carolina
Conditions: Cognitive Impairment, Dementia, Post ICU Syndrome, Critical Illness, Cognitive Impairment, Mild
Messy Memories: Mobile Application Therapy Following Critical Illness
Recruiting
The overall goal of this study is to determine whether English-speaking adults who were discharged from an intensive care unit (ICU) at least one month ago and have some level of distress related to their ICU experience will be interested in, willing to use, and satisfied with a new mobile application (app) designed to help the user process a difficult memory. Participants must have internet access and a smartphone in order to use the app. The goal of the app is to help reduce the psychological... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
03/18/2024
Locations: Columbia University Irving Medical Center, New York, New York
Conditions: Critical Illness, Psychological Distress, Health Behavior
Multi-component Family Support Tool Intervention (FST)
Recruiting
The National Academy of Medicine and the National Institutes of Health have called for urgent action to improve the care delivered to the nearly 1,000,000 older Americans who die in intensive care units (ICUs) annually or survive with substantial impairments. These patients often die with distressing symptoms and may receive more invasive, life-prolonging treatment than they would choose for themselves. Moreover, their family members acting as surrogate decision-makers often experience lasting p... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
03/11/2024
Locations: Baystate Medical Center, Springfield, Massachusetts +6 locations
Conditions: Critical Illness
NIBP Validation Study
Recruiting
The purpose of this study is to compare measurements of blood pressure (BP) between the Philips non-invasive blood pressure (NIBP) system (including NIBP cuff and portable patient monitor) and invasive radial arterial line (A-line) in critical care patients.
Gender:
All
Ages:
All
Trial Updated:
03/06/2024
Locations: Mayo Clinic Jacksonville, Jacksonville, Florida +1 locations
Conditions: Critical Illness
Eyecontrol coMmunication Platform for dEliRium manaGemEnt in Intensive Care Units (EMERGE)
Recruiting
The purpose of this research is to investigate whether addition of the EyeControl-Pro platform as an adjunct to standard guideline-based intensive care unit management of critically ill patients is effective in reducing delirium incidence and severity.
Gender:
All
Ages:
50 years and above
Trial Updated:
03/06/2024
Locations: Beth Israel Deaconess Medical Center, Boston, Massachusetts +2 locations
Conditions: Delirium, Delirium in Old Age, Critical Illness, Intensive Care Unit Delirium
Bringing to Light the Risk Factors And Incidence of Neuropsychological Dysfunction in ICU Survivors, 2nd Study
Recruiting
This BRAIN-ICU-2 study [Bringing to light the Risk factors And Incidence of Neuropsychological dysfunction (dementia) in ICU Survivors, 2nd Study] is in direct response to PAR-17-038 and will determine ICU patients' main paths to decline, maintenance, or recovery of brain function. We will answer gaps in knowledge about long-term outcome of post-ICU brain disease by following the remaining ICU survivors from the original BRAIN-ICU-1 study with complete cognitive testing for the first time ever t... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
03/04/2024
Locations: Rush University Medical Center, Chicago, Illinois +1 locations
Conditions: Critical Illness, Intensive Care Unit Delirium
Influences of High-fiber, Organic Whole-food Formula on the Gut Microbiome in Critically Ill Children
Recruiting
This study evaluates the effects of either Pediasure or Nourish formulas on the gastrointestinal microbiome in critically-ill children. Patients will be randomized to received either Pediasure or Nourish.
Gender:
All
Ages:
Between 1 year and 17 years
Trial Updated:
03/01/2024
Locations: Children's Hospital of Pittsburgh of UPMC, Pittsburgh, Pennsylvania
Conditions: Critical Illness, Dysbiosis, Pediatric ALL
A Study of Healthy Microbiome, Healthy Mind
Recruiting
Researchers are doing this study to find out if a high fermented food diet is tolerable, and if it will help improve quality of life after surviving a critical illness, including severe COVID-19, by promoting gut health recovery and decreasing gut inflammation.
Gender:
All
Ages:
18 years and above
Trial Updated:
02/26/2024
Locations: Mayo Clinic Minnesota, Rochester, Minnesota
Conditions: Critical Illness, COVID-19, PICS, Cognitive Impairment, Mental Health Impairment, Weakness, Muscle, Dysbiosis
Driving Rehabilitation and Innovation for Evaluating Risk in Post-Intensive Care Unit Survivors
Recruiting
Older adults are at risk for ICU-acquired cognitive decline discernible from clinical, biological, and imaging- related changes in the brain following delirium and critical illness. Our Driving Rehabilitation and Innovation for Evaluating Risk in Post Intensive Care Unit Survivors (DRIVE-PICS) application seeks to implement in-vehicle kinematic driving data with neurocognitive assessments for essential formative work to develop data-based insights into driving behaviors. DRIVE-PICS is designed t... Read More
Gender:
All
Ages:
40 years and above
Trial Updated:
02/26/2024
Locations: Baylor Scott and White Health Medical Center At Temple, Temple, Texas
Conditions: Delirium, Critical Illness, Drive
Personalized Nutrition Delivery to Improve Resilience in Older Adult Trauma Patients
Recruiting
This is a Pilot study designed to set up for an randomized clinical trial (RCT) comparing the SeND Home pathway to a standard of care nutrition delivery in critically ill older adult trauma patients. Subjects will be randomized 3:1 to either SeND Home precision nutrition pathway or control arm. Subjects randomized to the SeND Home arm will receive oral nutrition supplements (ONS) up to 3 times per day while in the hospital and for 4 weeks after discharge. Subjects in the standard of care arm wil... Read More
Gender:
All
Ages:
60 years and above
Trial Updated:
02/12/2024
Locations: Duke University Hospital, Durham, North Carolina
Conditions: Trauma, Critical Illness
Evaluating the Unmet Needs of Older Adults to Promote Functional Recovery After a Critical Illness
Recruiting
This is a prospective longitudinal study that will evaluate the unmet needs of older adults (65 and older) who return home (either directly or after short-term rehab) after an ICU hospitalization, evaluate the association of these unmet needs with clinically relevant outcomes, and assess barriers and facilitators to addressing these unmet needs. The proposed research will inform the development and evaluation of a subsequent intervention to improve functional outcomes among older ICU survivors,... Read More
Gender:
All
Ages:
65 years and above
Trial Updated:
01/25/2024
Locations: Yale New Haven Hospital, New Haven, Connecticut
Conditions: Critical Illness, Illness, Critical