There are currently 54 active clinical trials seeking participants for Diabetes Mellitus research studies. The states with the highest number of trials for Diabetes Mellitus participants are California, Florida, Texas and North Carolina.
Radiotracer-Based Perfusion Imaging of Patients With Peripheral Arterial Disease
NCT03622359
Recruiting
The aim of this clinical study is to 1) establish a healthy database for nuclear perfusion imaging of the lower extremities and 2) assess the prognostic value of radiotracer-based perfusion imaging for predicting clinical outcomes in patients with peripheral artery disease (PAD) who are undergoing lower extremity revascularization procedures. We hypothesize that radiotracer imaging of the lower extremities will provide a sensitive non-invasive imaging tool for quantifying regional abnormalities... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
03/27/2025
Locations: Nationwide Children's Hospital, Columbus, Ohio
Conditions: Diabetes Mellitus, Peripheral Artery Disease, Chronic Limb-Threatening Ischemia
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Impact of Per Oral Pyloromyotomy (POP) on Glycemic Control in Diabetes
NCT04696159
Recruiting
This study will assess changes in glycemic control in 40 patients with diabetes who undergo per-oral pyloromyotomy (POP) for medically refractory gastroparesis.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
07/09/2024
Locations: Cleveland Clinic Foundation, Cleveland, Ohio
Conditions: Diabetes Mellitus, Gastroparesis With Diabetes Mellitus, Gastroparesis
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Early Tracking of Childhood Health Determinants (ETCHED) Study
NCT03481829
Recruiting
Background: Children s weight has increased sharply in recent years. This may put them at higher risk for health problems. High blood glucose in a pregnant mother and too much weight gain during pregnancy also may have long-term effects on the child s health. Children who become overweight or obese during childhood tend to remain so as adults. Researchers want to study many risk factors during and after pregnancy, and how these affect a child s development. They will also follow the mother s he... Read More
Gender:
ALL
Ages:
Between 1 day and 99 years
Trial Updated:
06/28/2025
Locations: NIDDK, Phoenix, Phoenix, Arizona
Conditions: Obesity, Fatty Liver, Diabetes Mellitus
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Family Investigation of Nephropathy and Diabetes (F.I.N.D.)
NCT00342927
Recruiting
The Family Investigation of Nephropathy and Diabetes (FIND) is a multicenter study designed to identify genetic determinants of diabetic kidney disease. FIND will be conducted in eleven centers and in many ethnic groups throughout the United States. Two different strategies will be used to localize genes predisposing to kidney disease: a family-based genetic linkage study and a case-control study that utilizes admixture linkage disequilibrium. The center based at the Phoenix office of the Nation... Read More
Gender:
ALL
Ages:
Between 18 years and 99 years
Trial Updated:
06/27/2025
Locations: NIDDK, Phoenix, Phoenix, Arizona
Conditions: Diabetic Nephropathy, Diabetes Mellitus, Diabetic Kidney Disease, Albuminuria
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A Fruit and Vegetable Prescription Program
NCT06107816
Recruiting
Dietary intake of fruits and vegetables (F\&V) is a cornerstone for the treatment of type 2 diabetes, however less than 16% of Hispanic adults consume the recommended number of servings each day. F\&V prescription (F\&V Rx) programs are embedded into clinical settings and provide patients with vouchers to purchase F\&V at local retailers. The proposed study aims to test the effects of a F\&V Rx on diabetes self-management education and support (DSME/S) uptake and retention, dietary intake of F\&... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
06/24/2025
Locations: Penn State Health St. Joseph Downtown Campus, Reading, Pennsylvania
Conditions: Diabetes Mellitus, Diabetes Complications
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Genetic Studies of Insulin and Diabetes
NCT00001987
Recruiting
The study will allow researchers to obtain blood, plasma, DNA, and RNA for genetic studies of insulin. There will be a focus on the causes of insulin resistance and diabetes mellitus. Insulin is a hormone found in the body that controls the level of sugar in the blood. Insulin resistance refers to conditions like diabetes when insulin does not work properly. In this study researchers would like to compare patients with diabetes and other forms of insulin resistance to normal individuals. The stu... Read More
Gender:
ALL
Ages:
Between 6 months and 120 years
Trial Updated:
06/21/2025
Locations: National Institutes of Health Clinical Center, Bethesda, Maryland
Conditions: Diabetes Mellitus, Severe Insulin Resistance
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Increasing CGM Use Among Patients With T2D
NCT06638099
Recruiting
Study Overview: This interventional study aims to assess whether training healthcare professionals (HCPs) increases the number of continuous glucose monitor (CGM) prescriptions for patients with Type 2 Diabetes in a Federally Qualified Health Center serving a predominantly Hispanic/Latino population. Research Questions: Does HCP training enhance CGM prescription rates in a primary care setting? Does receiving a CGM prescription lead to improved Type 2 Diabetes control, as measured by Hemoglob... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
06/17/2025
Locations: Innercare Inc, El Centro, California +1 locations
Conditions: Diabetes, Diabetes Mellitus, Diabetes Mellitus Type 2, Diabetes Mellitus Type 2 (T2DM)
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SPYRAL GEMINI Pilot Study
NCT06907147
Recruiting
The purpose of the SPYRAL GEMINI Pilot Study is to evaluate that multi-organ denervation with the Gemini System is safe and provide evidence of blood pressure reduction when studied in an uncontrolled hypertensive population with and without high cardiovascular risk.
Gender:
ALL
Ages:
Between 18 years and 80 years
Trial Updated:
06/17/2025
Locations: Piedmont Heart Institute, Atlanta, Georgia +5 locations
Conditions: Hypertension, Vascular Diseases, Cardiovascular Diseases, Chronic Kidney Diseases, Diabetes Mellitus
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A Study of Mesothelin-Targeted CAR T-Cell Therapy in People With Esophagogastric Cancer
NCT06623396
Recruiting
Participants will have a sample of their white blood cells, called T cells, collected using a procedure called leukapheresis. The collected T cells will be sent to a laboratory at Memorial Sloan Kettering to be changed (modified) to become MSLN-targeted CAR T cells, the CAR T-cell therapy that participants will receive during the study. Participant study therapy will take about 3-4 weeks.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
06/11/2025
Locations: Memorial Sloan Kettering Basking Ridge (Limited Protocol Activities), Basking Ridge, New Jersey +6 locations
Conditions: Mesothelin Positive, Mesothelin-Expressing Tumors, Esophageal Adenocarcinoma, Esophageal Adenocarcinomas, Esophagogastric Adenocarcinoma, Peritoneal Carcinomatosis, Breast Neoplasms, Diabetes Mellitus
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Pioglitazone Versus Empagliflozin for Chronic Pancreatitis/Recurrent Acute Pancreatitis Associated Diabetes Mellitus
NCT06729996
Recruiting
The purpose of this study is to evaluate efficacy of pioglitazone (PIO) versus empagliflozin (EMPA) to improve glycemic control in people with Chronic Pancreatitis (CP) or Recurrent Acute Pancreatitis (RAP) associated with Diabetes Mellitus (DM). To evaluate mixed meal response in PIO versus EMPA group to better understand physiology of both therapies in CP-DM.
Gender:
ALL
Ages:
Between 18 years and 70 years
Trial Updated:
06/05/2025
Locations: Mayo Clinic, Rochester, Minnesota +1 locations
Conditions: Pancreatitis, Chronic, Pancreatitis, Acute, Diabetes Mellitus
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SPYRAL AFFIRM Global Study of RDN With the Symplicity Spyral RDN System in Subjects With Uncontrolled HTN
NCT05198674
Recruiting
The purpose of this single-arm interventional study is to evaluate the long-term safety, efficacy, and durability of the Symplicity Spyral system in subjects treated with renal denervation. Additionally, long-term follow-up data will also be collected from eligible subjects previously treated in the SPYRAL PIVOTAL-SPYRAL HTN-OFF MED and SPYRAL HTN-ON MED studies.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
06/02/2025
Locations: University of Alabama at Birmingham (UAB) Hospital, Birmingham, Alabama +99 locations
Conditions: Hypertension, Vascular Diseases, Cardiovascular Diseases, Chronic Kidney Diseases, Diabetes Mellitus
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Innovative Multi-Variable Biofeedback for Improving Gait Performance in Individuals With Diabetic Peripheral Neuropathy
NCT06591780
Recruiting
This study aims to collect data to improve gait function in individuals with Diabetic Peripheral Neuropathy (DPN). The primary goals are to evaluate: * Biomechanical mechanisms contributing to abnormal plantar pressure and propulsion during gait in individuals with DPN * Biofeedback-induced changes in plantar pressure, propulsion, and biomechanics during gait in individuals with DPN The participants will be required to complete * Questionnaires * Clinical examination * 3-Dimensional gait ana... Read More
Gender:
ALL
Ages:
Between 45 years and 90 years
Trial Updated:
06/02/2025
Locations: Florida Institute for Human and Machine Cognition, Pensacola, Florida
Conditions: Diabetic Peripheral Neuropathy, Diabetes Mellitus
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