There are currently 68 active clinical trials seeking participants for Diabetes Mellitus research studies. The states with the highest number of trials for Diabetes Mellitus participants are California, Florida, Texas and North Carolina.
Radiotracer-Based Perfusion Imaging of Patients With Peripheral Arterial Disease
NCT03622359
Recruiting
The aim of this clinical study is to 1) establish a healthy database for nuclear perfusion imaging of the lower extremities and 2) assess the prognostic value of radiotracer-based perfusion imaging for predicting clinical outcomes in patients with peripheral artery disease (PAD) who are undergoing lower extremity revascularization procedures. We hypothesize that radiotracer imaging of the lower extremities will provide a sensitive non-invasive imaging tool for quantifying regional abnormalities... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
03/12/2024
Locations: Nationwide Children's Hospital, Columbus, Ohio
Conditions: Diabetes Mellitus, Peripheral Artery Disease, Chronic Limb-Threatening Ischemia
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Impact of Per Oral Pyloromyotomy (POP) on Glycemic Control in Diabetes
NCT04696159
Recruiting
This study will assess changes in glycemic control in 40 patients with diabetes who undergo per-oral pyloromyotomy (POP) for medically refractory gastroparesis.
Gender:
All
Ages:
18 years and above
Trial Updated:
01/30/2024
Locations: Cleveland Clinic Foundation, Cleveland, Ohio
Conditions: Diabetes Mellitus, Gastroparesis With Diabetes Mellitus, Gastroparesis
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Social Risk Score, Clinical Decision Support Tool and Closed Loop Referral for Social Risk Screen and Referral
NCT05574699
Recruiting
The overarching goal of this project is to leverage health information technology (HIT) to integrate available digital information on social needs to improve care for racial and ethnic minorities and socially disadvantaged populations with chronic diseases. In the previous phases of this project the investigators developed a social risk score to identify social needs among medically under-served patients with special emphasis on application among African American patients with low income and ch... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
05/15/2024
Locations: Johns Hopkins GreenSpring Station, Baltimore, Maryland +4 locations
Conditions: Chronic Disease, Diabetes Mellitus, Hypertension, Congestive Heart Failure
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Plant-based Diet for Kidney Transplant Recipients
NCT06186843
Recruiting
The goal of this clinical trial is to evaluate cardiometabolic and inflammatory parameters in kidney transplant recipients after transitioning to a plant-based diet (PBD). The main aims of the study are as follows: To test the feasibility of transiting renal allograft recipients who are > 3 months post-transplant to a PBD To study the effect of a PBD on cardiometabolic parameters in kidney transplant recipients To assess the effect of a PBD on peripheral blood Th17/Treg ratio and systemic infla... Read More
Gender:
All
Ages:
Between 18 years and 80 years
Trial Updated:
05/15/2024
Locations: Transplant Institute, Washington, District of Columbia
Conditions: Kidney Disease, Chronic, Transplant Complication, Hypertension, Diabetes Mellitus, Metabolic Syndrome, Inflammation, Kidney Transplant Failure, Dietary Habits
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SPYRAL AFFIRM Global Study of RDN With the Symplicity Spyral RDN System in Subjects With Uncontrolled HTN
NCT05198674
Recruiting
The purpose of this single-arm interventional study is to evaluate the long-term safety, efficacy, and durability of the Symplicity Spyral system in subjects treated with renal denervation. Additionally, long-term follow-up data will also be collected from eligible subjects previously treated in the SPYRAL PIVOTAL-SPYRAL HTN-OFF MED and SPYRAL HTN-ON MED studies.
Gender:
All
Ages:
18 years and above
Trial Updated:
05/13/2024
Locations: University of Alabama at Birmingham (UAB) Hospital, Birmingham, Alabama +81 locations
Conditions: Hypertension, Vascular Diseases, Cardiovascular Diseases, Chronic Kidney Diseases, Diabetes Mellitus
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Screening and Nutrition for Patients With Diabetes: A Pilot Study
NCT05674110
Recruiting
The goal of this project is to provide diabetes self-management education and support (DSMES) and simultaneously address food insecurity for a high-risk, ethnically diverse adult population who participate in a food pantry. This project will utilize a Community-Based Participatory Research model (CBPR). Community representatives will engage in project implementation by participating in designing the messaging for cultural impact and advising in study operations. This intervention targets food pa... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
05/13/2024
Locations: Villanova University, Villanova, Pennsylvania
Conditions: Diabetes Mellitus
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Genetic Studies of Insulin and Diabetes
NCT00001987
Recruiting
The study will allow researchers to obtain blood, plasma, DNA, and RNA for genetic studies of insulin. There will be a focus on the causes of insulin resistance and diabetes mellitus. Insulin is a hormone found in the body that controls the level of sugar in the blood. Insulin resistance refers to conditions like diabetes when insulin does not work properly. In this study researchers would like to compare patients with diabetes and other forms of insulin resistance to normal individuals. The stu... Read More
Gender:
All
Ages:
Between 6 months and 120 years
Trial Updated:
05/11/2024
Locations: National Institutes of Health Clinical Center, Bethesda, Maryland
Conditions: Diabetes Mellitus, Severe Insulin Resistance
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Early Tracking of Childhood Health Determinants (ETCHED) Study
NCT03481829
Recruiting
Background: Children s weight has increased sharply in recent years. This may put them at higher risk for health problems. High blood glucose in a pregnant mother and too much weight gain during pregnancy also may have long-term effects on the child s health. Children who become overweight or obese during childhood tend to remain so as adults. Researchers want to study many risk factors during and after pregnancy, and how these affect a child s development. They will also follow the mother s he... Read More
Gender:
All
Ages:
Between 1 day and 99 years
Trial Updated:
05/07/2024
Locations: NIDDK, Phoenix, Phoenix, Arizona
Conditions: Obesity, Fatty Liver, Diabetes Mellitus
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Assess the Efficacy and Safety of Repeat Intravitreal Injections of Foselutoclax (UBX1325) in Patients With DME (ASPIRE)
NCT06011798
Recruiting
The goal of this clinical trial is to assess the efficacy and safety of multiple doses of foselutoclax (UBX1325) in patients with Diabetic Macular Edema. The main questions the study aims to answer are: Assess the efficacy of foselutoclax compared to aflibercept Assess the safety and tolerability of foselutoclax
Gender:
All
Ages:
18 years and above
Trial Updated:
05/03/2024
Locations: California Retina Consultants, Bakersfield, California +20 locations
Conditions: Diabetic Macular Edema, Retinal Disease, Macular Edema, Diabetes Mellitus, Diabetic Retinopathy, Retinal Degeneration, Retinal Diseases, Eye Diseases, Edema
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Hyperbaric Oxygen Therapy for Cognition in Diabetic Elderly at High Dementia Risk
NCT03036254
Recruiting
An urgent need exists to identify effective interventions to arrest or reverse dementia and cognitive loss at its earliest stages. The proposed pilot randomized clinical trial will investigate the short and long-term effects of hyperbaric oxygen therapy on cognitive functioning, cerebral blood flow, and glucose uptake in diabetic elderly with mild cognitive impairment. and provide the basis for a large-scale multi-center study of hyperbaric oxygen therapy effects on cognition in diabetes. The po... Read More
Gender:
All
Ages:
65 years and above
Trial Updated:
05/01/2024
Locations: Icahn School of Medicine at Mount Sinai, New York, New York +3 locations
Conditions: Diabetes Mellitus
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Dapagliflozin in Patients With Atrial Fibrillation (DAPA-AF)
NCT05174052
Recruiting
The study will investigate the effect of Dapagliflozin on atrial fibrillation (AF) burden. AF burden will be defined as the percent of time spent in AF over a 2-week period, assessed by noninvasive continuous heart rhythm monitoring at baseline and at 3 months, quality of life (QOL) and validated echocardiographic indices of atrial myopathy. This knowledge will enable us to study the therapeutic potential of SGLT2i as a novel adjunct treatment for patients with DM and AF. Patients with paroxysma... Read More
Gender:
All
Ages:
Between 18 years and 85 years
Trial Updated:
04/29/2024
Locations: University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma
Conditions: Atrial Fibrillation, Diabetes Mellitus
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People With CHC Who Achieved a Sustained Virological Response Following Therapy With Direct Acting Antiviral Agents
NCT03520660
Recruiting
Background: Chronic hepatitis C infects the liver. It may scar the liver. This is called cirrhosis and may lead to liver cancer or death. Current chronic hepatitis C treatments cure most people. But some keep getting complications even after it is cured. Researchers want to study why. Objective: To study the course and complications of liver disease after cure of hepatitis C infection. Eligibility: Adults 18 years and older infected with chronic hepatitis C virus who were never treated or w... Read More
Gender:
All
Ages:
Between 18 years and 120 years
Trial Updated:
04/27/2024
Locations: National Institutes of Health Clinical Center, Bethesda, Maryland
Conditions: Diabetes Mellitus, Hepatitis C, Chronic, Cardiovascular Diseases
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