There are currently 86 active clinical trials seeking participants for HIV Infections research studies. The states with the highest number of trials for Autism participants are California, New York, Florida and Texas.
Use of a Screening Tool to Describe HIV-Related Cancer Burden and Patient Characteristics in the AMC
Recruiting
This study is being done to understand how many people with HIV (PWH) present for cancer care across the AIDS Malignancy Consortium in the United States and if there are reasons that some PWH choose to participate, or not in cancer clinical trials. Optional quality of life surveys will be used to learn more about how HIV and cancer and HIV and cancer treatment affect people.
Gender:
All
Ages:
18 years and above
Trial Updated:
03/14/2024
Locations: Moores UCSD Cancer Center, La Jolla, California +9 locations
Conditions: HIV-Associated Malignant Neoplasm, HIV Infections, Cancer, AIDS Related Lymphoma, AIDS-related Kaposi Sarcoma, AIDS-Related Malignancy, Anal Cancer, HPV-Related Malignancy
SmartSteps: A Context-Aware, PrEP Adherence Intervention for Individuals With Substance Use Disorder
Recruiting
This is a single-arm, observational study of HIV-negative MSM with substance use disorder. Those who meet pre-screening criteria will attend a Screening Visit (Visit 1), where the informed consent process will be conducted and study eligibility will be confirmed. Eligible participants will attend three additional visits over the course of the study - the Enrollment Visit (Visit 2), Month 1 Visit (Visit 3), and Month 2 Visit (Visit 4). Participants will take one PrEP digital pill per day, for 60... Read More
Gender:
Male
Ages:
18 years and above
Trial Updated:
03/12/2024
Locations: Fenway Health, Boston, Massachusetts
Conditions: HIV Infections, Substance Use, Adherence, Medication, Adherence, Treatment
Contingency Management for Cannabis Use for Persons With HIV
Recruiting
The purpose of this study is to determine the feasibility and impact of 28-days of monitored abstinence from cannabis use on symptoms of depression and anxiety, pain, sleep, cannabis use withdrawal, HIV viral load and biomarkers of systemic inflammation among PLWH and who use cannabis regularly (weekly or more often). This will be a single arm pilot feasibility trial involving a contingency management program to induce cannabis abstinence. Specifically, the contingency management program will pr... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
03/11/2024
Locations: Center for Neurobehavioral Research on Addiction, Houston, Texas +1 locations
Conditions: Marijuana, HIV Infections
Digital Community to Improve Health in Rural Areas
Recruiting
The study is a cluster randomized controlled trial developed in counties located in Appalachia and the Midwest. We will prioritize counties from states with high risk for HIV and HCV infection associated with injection drug use.
Gender:
All
Ages:
Between 18 years and 99 years
Trial Updated:
03/08/2024
Locations: University of Pennsylvania, Philadelphia, Pennsylvania
Conditions: HIV Infections, Hepatitis C Virus Infection
A Study to Investigate the Potential Drug-Drug Interaction Between VH4524184 and Oral Contraceptive (Loestrin) in Healthy Adult Female Participants
Recruiting
This study aims to assess any impact of VH4524184 on the pharmacokinetic (PK) profile of an ethinyl estradiol (EE) and norethindrone acetate (NEA) containing oral contraceptive (OC) administered to healthy adult female participants.
Gender:
Female
Ages:
Between 18 years and 45 years
Trial Updated:
03/07/2024
Locations: GSK Investigational Site, San Antonio, Texas
Conditions: HIV Infections
Heart Failure Polypill at a Safety Net Hospital
Recruiting
A novel four-drug regimen for heart failure with reduced ejection fraction (HFrEF) extends patients' life expectancy by an average of 6 years compared to traditional therapies, in addition to improving quality of life. Unfortunately, uptake of this complex multi-drug regimen has been low, especially among underserved communities with barriers to medication adherence. Although combination tablets have transformed access to care for conditions such as HIV and tuberculosis, no combination pill is a... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
03/06/2024
Locations: Zuckerberg San Francisco General Hospital, San Francisco, California
Conditions: Heart Failure With Reduced Ejection Fraction, HIV Infections
Optimizing CAB-LA as PrEP for Women Who Inject Drugs
Recruiting
The goal of this study is to elicit information crucial for designing strategies to support engagement in cabotegravir, a long-acting injectable form of pre-exposure prophylaxis (PrEP) to reduce HIV risk among women who inject drugs (WWID), a population with high unmet need that has been understudied in all phases of PrEP research. The main questions this study aims to answer are: How do WWID perceive long-acting injectable cabotegravir (CAB-LA) as a HIV prevention tool? If and how their decisi... Read More
Gender:
Female
Ages:
18 years and above
Trial Updated:
03/01/2024
Locations: Prevention Point Philadelphia, Philadelphia, Pennsylvania
Conditions: HIV Infections, Opioid Use, Trauma, Psychological
Single Dose Pharmacokinetics of Doravirine in HIV-infected Pregnant Women
Recruiting
The purpose of this research study is to evaluate the effect of body changes in pregnancy on doravirine concentrations, to determine what dose of doravirine should be used. Study participants will remain on their normal antiretroviral medications (ARVs) while participating in this study as prescribed by their regular clinic provider. Study participants will come to the research clinic for three sampling visits throughout their time as a participant. Study participants will only take one dose of... Read More
Gender:
Female
Ages:
18 years and above
Trial Updated:
02/27/2024
Locations: University of North Carolina at Chapel Hill, Chapel Hill, North Carolina
Conditions: HIV Infections, Pregnancy Related
Study of Cobicistat-Boosted Atazanavir (ATV/co), Cobicistat-Boosted Darunavir (DRV/co) and Emtricitabine/Tenofovir Alafenamide (F/TAF) in Children With HIV
Recruiting
The goal of this clinical study is to learn more about the safety and dosing of study drugs, cobicistat-boosted Atazanavir (ATV/co), cobicistat-boosted darunavir (DRV/co) and emtricitabine/tenofovir alafenamide (F/TAF), in children (age ≥ 4 weeks to < 18 years) with HIV.
Gender:
All
Ages:
Between 4 weeks and 17 years
Trial Updated:
02/16/2024
Locations: Pediatric Infectious Disease Associates, Long Beach, California +31 locations
Conditions: Acquired Immune Deficiency Syndrome (AIDS), HIV Infections
Proof of Concept Treatment Study of Orally Administered VH4004280 or VH4011499 in HIV-1 Infected Adults
Recruiting
The primary purpose of the study is to evaluate the antiviral activity of orally administered VH4004280 and VH4011499 monotherapy over 10 days in human immunodeficiency virus (HIV-1) infected Treatment-Naïve (TN) participants.
Gender:
All
Ages:
Between 18 years and 65 years
Trial Updated:
02/14/2024
Locations: GSK Investigational Site, Bakersfield, California +42 locations
Conditions: HIV Infections
A Study to Investigate the Pharmacokinetics, Safety, and Tolerability of Two Different Formulations of Long-acting Cabotegravir in Healthy Adult Participants
Recruiting
The primary purpose of the study is to investigate the safety, tolerability, and pharmacokinetic (PK) profiles of two different cabotegravir formulations in healthy adult participants. The study will initially start with the assessment of Cabotegravir Formulation F. Once the clinical batch of Cabotegravir Formulation G is available and depending on data for Formulation F, this formulation will be assessed.
Gender:
All
Ages:
Between 18 years and 55 years
Trial Updated:
02/13/2024
Locations: GSK Investigational Site, Austin, Texas
Conditions: HIV Infections
Peer Supported Collaborative Care Mental Health and Substance Use Disorder Care
Recruiting
This is a research study to assess the effectiveness of a peer-led collaborative care model for integrating treatment for substance use and or mental health disorders into HIV care settings. Depending on whether or not participants enroll in this study, participants will be assigned randomly (by chance, like drawing a number from a hat) to one of two groups. In group 1, participants would receive usual clinical care. In group 2, participants would work with a peer-case manager who would help su... Read More
Gender:
All
Ages:
Between 18 years and 99 years
Trial Updated:
02/09/2024
Locations: Johns Hopkins Hospital, Baltimore, Maryland
Conditions: HIV Infections, Substance Use Disorders, Mental Health Disorder, Addiction, Opioid Use, Drug Use