There are currently 88 active clinical trials seeking participants for HIV Infections research studies. The states with the highest number of trials for HIV Infections participants are California, New York, Florida and Texas.
Evaluation of Trimer 4571 Therapeutic Vaccination in Adults Living With HIV on Suppressive Antiretroviral Therapy
NCT04985760
Recruiting
Trimer 4571 is a vaccine designed to stimulate the development of broadly neutralizing antibodies (bnAbs) against HIV. Trimer 4571 is investigational, meaning it is not approved by the US Food and Drug Administration (FDA). There is limited human experience with the Trimer 4571 vaccine administered with aluminum hydroxide (alum) and the vaccine has not been tested in people with HIV prior to this study although it has been tested in healthy volunteers. The goal of this study is to see if Trimer... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
01/17/2024
Locations: AIDS Clinical Trials Unit/The Ohio State University, Columbus, Ohio +1 locations
Conditions: HIV Infections
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ETE Interventions in the Dental Setting
NCT05584501
Recruiting
The purpose of this study is to use information technology (IT) to support the delivery of HIV prevention and care best practices in the dental care setting to meet the Department of Health and Human Services (DHHS) Ending the HIV Epidemic (ETE) goals.
Gender:
All
Ages:
18 years and above
Trial Updated:
05/10/2024
Locations: Columbia University Irving Medical Center / NewYork-Presbyterian Hospital, New York, New York +1 locations
Conditions: HIV Infections
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WiseApp for Spanish Speakers Living With HIV
NCT05398185
Recruiting
This study aims to conduct a 12-month randomized controlled trial to adapt the mobile app, WiseApp, and a smart pill dispenser for Spanish-speaking people living with HIV (PLWH) in the New York City (NYC) area and La Romana, Dominican Republic (DR). The study will assess the efficacy and sustainability of WiseApp as well as identify barriers with its widespread use among Spanish speakers. With disproportionately high rates of HIV in the New York City area and the Dominican Republic, this project... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
05/09/2024
Locations: Columbia University Irving Medical Center, New York, New York +1 locations
Conditions: HIV Infections, Acquired Immune Deficiency Syndrome, Sexually Transmitted Diseases, Viral
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VH4524184 Proof-of-Concept in Treatment-Naïve Adults Living With HIV-1
NCT06214052
Recruiting
The purpose of this study is to evaluate the safety, tolerability, ability of VH4524184 when given alone to reduce the amount of HIV (viral load) in people with HIV-1 infection who have never received antiretroviral therapy (treatment-naïve). Data from this study will be used to decide how VH4524184 can be best included in a full-treatment regimen for HIV-1 in the future.
Gender:
All
Ages:
Between 18 years and 65 years
Trial Updated:
05/08/2024
Locations: GSK Investigational Site, Bakersfield, California +26 locations
Conditions: HIV Infections
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Study of Cobicistat-Boosted Atazanavir (ATV/co), Cobicistat-Boosted Darunavir (DRV/co) and Emtricitabine/Tenofovir Alafenamide (F/TAF) in Children With HIV
NCT02016924
Recruiting
The goal of this clinical study is to learn more about the safety and dosing of study drugs, cobicistat-boosted Atazanavir (ATV/co), cobicistat-boosted darunavir (DRV/co) and emtricitabine/tenofovir alafenamide (F/TAF), in children (age ≥ 4 weeks to < 18 years) with HIV.
Gender:
All
Ages:
Between 4 weeks and 17 years
Trial Updated:
05/08/2024
Locations: Pediatric Infectious Disease Associates, Long Beach, California +33 locations
Conditions: Acquired Immune Deficiency Syndrome (AIDS), HIV Infections
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A Systems Analysis and Improvement Approach for Optimizing HIV Service Delivery in Syringe Services Programs
NCT06025435
Recruiting
The goal of this clinical trial is to assess the effectiveness of an evidence-based, organizational-level implementation strategy, the Systems Analysis and Improvement Approach, in improving HIV service delivery (SAIA-SSP-HIV) in U.S. syringe services programs (SSPs). The main questions it aims to answer are: Does SAIA-SSP-HIV improve delivery of HIV services (including the proportion of SSP participants receiving HIV testing) compared to implementation as usual (IAU)? Does SAIA-SSP-HIV result... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
05/06/2024
Locations: University of California, San Diego, San Diego, California
Conditions: HIV Infections
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AURORA Study-A Transformative Approach to Support PrEP Medication Persistence
NCT06072443
Recruiting
This study is designed to test the hypothesis that, compared to oral PrEP, use of CAB-LA in underserved populations in a real-world setting supported by a digital health companion program will be associated with greater medication adherence, persistence, retention-in-care, and improved PROs. Patients in the study will receive current standard care for HIV prevention and be offered enrollment in the digital health companion program. Goal of the study is to evaluate medication adherence and persi... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
04/29/2024
Locations: West Virginia Health Right, Charleston, West Virginia
Conditions: HIV Infections
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Exploring, Predicting, and Intervening on Long-term Viral Suppression Electronically
NCT06370780
Recruiting
Despite the widespread availability of effective antiretroviral therapy (ART) in the United States, there remains significant numbers of people living with HIV (PLWH) who fail to achieve and or maintain viral suppression (VS). Disparities persist with the lowest levels of VS among Black individuals, people who use drugs, youth ages 18-24 and people residing in rural areas. Investigators will examine the syndemics underlying these outcomes including substance use, mental health, and barriers to H... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
04/25/2024
Locations: University of California, Los Angeles, Los Angeles, California
Conditions: HIV Infections
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A Study to Evaluate the Efficacy, Safety, Participant Choice and Preference of an Oral Once-daily Regimen or a Long-acting Injectable Regimen Every Two Months for Treatment of Human Immunodeficiency Virus (HIV-1) in Adults Who Have Not Previously Taken Antiretroviral Therapy
NCT05917509
Recruiting
This is a multicentre study carried out in participants living with human immunodeficiency virus type 1 (HIV-1) who have not previously been treated with any antiretroviral therapies. The study will investigate two 2-drug regimens for the treatment of HIV-1: a fixed-dose combination oral tablet of dolutegravir/lamivudine (DTG/3TC) and cabotegravir plus rilpivirine long-acting agents (CAB + RPV LA). All participants will initially receive DTG/3TC once daily, and once virologic suppression is atta... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
04/24/2024
Locations: GSK Investigational Site, Birmingham, Alabama +56 locations
Conditions: HIV Infections
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An Electronic Health Record-based Approach to Increase PrEP Knowledge and Uptake: the EMC2 PrEP Strategy
NCT05709860
Recruiting
This study is being conducted to investigate a strategy that may improve knowledge and uptake of pre-exposure prophylaxis for HIV prevention (PrEP) among cisgender women in primary care.
Gender:
Female
Ages:
18 years and above
Trial Updated:
04/23/2024
Locations: Northwestern University, Chicago, Illinois
Conditions: HIV Infections, Electronic Health Record, Primary Health Care
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Alcohol Misuse, Gut Microbial Dysbiosis and PrEP Care Continuum: Application and Efficacy of SBIRT Intervention
NCT06005298
Recruiting
This randomized control trial study among Pre-exposure prophylactic users (PrEP) aims to learn and determine the efficacy of Screening, brief intervention, and referral to treatment (SBRIT) in reducing the risk of alcohol use. The main questions it aims to answer are: How alcohol use impacts the PrEP continuum and to understand how early intervention and treatment approach affects alcohol use and PrEP adherence. Investigate the effectiveness of the SBIRT intervention in preventing hazardous alc... Read More
Gender:
All
Ages:
Between 18 years and 85 years
Trial Updated:
04/22/2024
Locations: University of Louisville, Louisville, Kentucky
Conditions: Alcohol Use Disorder, Risk Behavior, Health, Dysbiosis, HIV Infections
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Use of a Screening Tool to Describe HIV-Related Cancer Burden and Patient Characteristics in the AMC
NCT05510908
Recruiting
This study is being done to understand how many people with HIV (PWH) present for cancer care across the AIDS Malignancy Consortium in the United States and if there are reasons that some PWH choose to participate, or not in cancer clinical trials. Optional quality of life surveys will be used to learn more about how HIV and cancer and HIV and cancer treatment affect people.
Gender:
All
Ages:
18 years and above
Trial Updated:
04/18/2024
Locations: Moores UCSD Cancer Center, La Jolla, California +10 locations
Conditions: HIV-Associated Malignant Neoplasm, HIV Infections, Cancer, AIDS Related Lymphoma, AIDS-related Kaposi Sarcoma, AIDS-Related Malignancy, Anal Cancer, HPV-Related Malignancy
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