There are currently 34 active clinical trials seeking participants for Inflammatory Bowel Diseases research studies. The states with the highest number of trials for Inflammatory Bowel Diseases participants are New York, California, Florida and Ontario.
A Study to Evaluate MORF-057 in Adults With Moderately to Severely Active UC
NCT05611671
Recruiting
This is a Phase 2b randomized, double-blind, placebo-controlled study to evaluate the safety and efficacy of three active dose regimens of MORF-057 in adult patients with moderately to severely active Ulcerative Colitis (UC).
Gender:
All
Ages:
Between 18 years and 85 years
Trial Updated:
06/13/2024
Locations: Clinical Study Site, Sun City, Arizona +136 locations
Conditions: Inflammatory Bowel Diseases, Colitis, Ulcerative
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A Phase 2 Study to Evaluate MORF-057 in Adults With Moderately to Severely Active Crohn's Disease
NCT06226883
Recruiting
This is a Phase 2, randomized, double-blind, placebo-controlled, multicenter study to evaluate the efficacy and safety of 2 active dose regimens of MORF-057 in adult study participants with moderately to severely active Crohn's disease (CD).
Gender:
All
Ages:
Between 18 years and 85 years
Trial Updated:
06/04/2024
Locations: Clinical Study Site, Lancaster, California +11 locations
Conditions: Inflammatory Bowel Diseases, Crohn's Disease
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Social Determinants of Health, Medication Use, and Quality of Life in Inflammatory Bowel Disease
NCT06266663
Recruiting
Optimizing health related-quality of life (HRQoL) for patients with inflammatory bowel disease (IBD), who often experience a relapsing disease course, is an essential component of care. Improving IBD disease control is linked to increased health-related quality of life. Even as many effective pharmacotherapies to promote disease control are available, evidence suggests that Hispanic and Non-Hispanic Black IBD patients may not receive full benefit from these therapies compared to their Non-Hispan... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
05/29/2024
Locations: Montefiore Hutchinson Campus, Bronx, New York +1 locations
Conditions: Inflammatory Bowel Diseases
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A Master Protocol (AMAZ): A Study of Mirikizumab (LY3074828) in Pediatric Participants With Ulcerative Colitis or Crohn's Disease (SHINE-ON)
NCT04844606
Recruiting
The main purpose of this study is to evaluate the long-term efficacy of mirikizumab in pediatric participants with ulcerative colitis (UC) or Crohn's disease (CD). The study will last about 172 weeks and may include up to 44 visits.
Gender:
All
Ages:
Between 2 years and 19 years
Trial Updated:
05/27/2024
Locations: UCSF Medical Center at Mission Bay, San Francisco, California +31 locations
Conditions: Ulcerative Colitis, Ulcerative Colitis Chronic, Inflammatory Bowel Diseases, Crohn's Disease
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Beta-Hydroxybutyrate Feasibility Treating IBD
NCT06351124
Recruiting
This clinical trial aims to understand the feasibility of patients taking ketone body supplement beta-hydroxybutyrate (BHB) for 4 weeks with a confirmed diagnosis of Crohn's disease and starting new therapy for active disease. The main questions it aims to answer are: BHB supplementation will be feasible and acceptable to patients. BHB supplementation will be associated with a reduction in systemic inflammation. BHB supplementation will be associated with a reduction in pro-inflammatory bacter... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
05/24/2024
Locations: University of Texas at Austin, Austin, Texas
Conditions: Crohn's Disease, Inflammatory Bowel Diseases
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A Comprehensive Self-Management Intervention for Individuals With Inflammatory Bowel Disease
NCT05651542
Recruiting
This study aims to test the feasibility, acceptability, and preliminary efficacy of a comprehensive self-management (CSM) intervention for people with inflammatory bowel disease (IBD). The CSM-IBD intervention is an adaption of the CSM intervention initially developed for individuals with irritable bowel syndrome. The intervention has eight sessions which cover an introduction to IBD, symptom tracking, cognitive behavioral strategies, relaxation, sleep, diet, and pain management.
Gender:
All
Ages:
Between 18 years and 75 years
Trial Updated:
05/06/2024
Locations: University of Washington, Seattle, Washington
Conditions: Inflammatory Bowel Diseases, Ulcerative Colitis, Crohn Disease
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Feasibility Test of Action Planning in Pediatric IBD
NCT06186752
Recruiting
The goal of this interventional study is to test the feasibility of a new communication tool, call MyIBD, in youth ages 13 to 19 years with inflammatory bowel disease. The main question[s] it aims to answer are: Is the MyIBD communication tool feasible to use in everyday clinical practice? Does the MyIBD tool have potential to improve patients' self-management skills and the quality of care they receive? Participants who receive the MyIBD intervention will complete surveys about their care at... Read More
Gender:
All
Ages:
Between 13 years and 19 years
Trial Updated:
04/30/2024
Locations: University of North Carolina-Chapel Hill School of Medicine, Chapel Hill, North Carolina
Conditions: Inflammatory Bowel Diseases
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The Effect of IBD Flares on Serum PSA
NCT03558048
Recruiting
This study will measure Prostate Specific Antigen (PSA) values in men with Inflammatory Bowel Disease (IBD) before, during, and following a flare. In addition, the effect of any PSA increase will be analyzed and correlated to the location of disease (rectal vs. other). Study findings may help men with IBD by identifying pitfalls in prostate cancer screening for this population and help to stratify and understand the effect IBD has on the prostatic milieu. By optimizing how men with IBD are scree... Read More
Gender:
Male
Ages:
Between 40 years and 69 years
Trial Updated:
04/22/2024
Locations: Northwestern Medicine, Chicago, Illinois
Conditions: Inflammatory Bowel Diseases, Prostate Cancer
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Internet-based Cognitive Behavioral Therapy in Inflammatory Bowel Disease
NCT05413941
Recruiting
While people of color are an increasing segment of the inflammatory bowel disease (IBD) population, they are currently underrepresented in research, including studies of psychological distress. Appreciation for psychological distress (anxiety, depression, perceived stress) as a driver of IBD activity has led to increased efforts to integrate psychological interventions into IBD medical care. Cognitive behavioral therapy (CBT) is the most studied psychotherapeutic approach in IBD and the one that... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
04/19/2024
Locations: Montefiore Hutchinson Campus, Bronx, New York
Conditions: Inflammatory Bowel Diseases, Psychological Distress
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IBD-Sleep: A Pilot Study Looking at Changes in Sleep Timing and IBD Symptoms
NCT06094608
Recruiting
This research study is testing whether changes in sleep timing and morning light treatment may have an impact on symptoms related to inflammatory bowel disease.
Gender:
All
Ages:
18 years and above
Trial Updated:
04/11/2024
Locations: University of Michigan, Ann Arbor, Michigan
Conditions: Inflammatory Bowel Diseases, Ulcerative Colitis, Crohn Disease
Register for Updates
Statin Therapy in Primary Sclerosing Cholangitis (PSC): a Multi-omics Study
NCT05912387
Recruiting
PSC is a liver disease that has no medical cure. Patients with PSC are at a greatly increased risk of cancer and infection. Additionally, many patients require a liver transplant. Progress towards a cure has been severely limited by an incomplete understanding of why patients develop PSC. The investigators aim to close this gap by conducting a pilot human study in patients with PSC, using statin therapy as a model
Gender:
All
Ages:
Between 18 years and 80 years
Trial Updated:
03/19/2024
Locations: Stanford University, Stanford, California
Conditions: Primary Sclerosing Cholangitis, Inflammatory Bowel Diseases
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Virtual Reality (VR) -Directed Brain Gut Behavioral Treatment (BGBT) for Inflammatory Bowel Disease (IBD) Inpatients
NCT06188793
Recruiting
The research is studying virtual reality (VR)-directed brain-gut behavioral therapy (BGBT) as a pain treatment option for hospitalized patients with inflammatory bowel disease (IBD). This study is being done to learn if VR-directed BGBT is feasible and acceptable for patients with IBD in addressing pain in the hospital setting. The study hypothesizes that: At least 75% of enrolled participants will complete the VR-directed BGBT inpatient program Hospitalized patients with IBD will find VR-dire... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
02/15/2024
Locations: University of Michigan, Ann Arbor, Michigan
Conditions: Inflammatory Bowel Diseases
Register for Updates