There are currently 21 active clinical trials seeking participants for Liver Diseases research studies. The states with the highest number of trials for Autism participants are California, Florida, Texas and New York.
A Trial of Post-Discharge Transitional Care for Patients With Chronic Liver Disease
Recruiting
Patients with complications of advanced liver disease often have difficulties after hospital discharge that result in early hospital readmission. Poor outcomes for these patients during this transitional time could be improved through the use of innovative transitional care models. This proposal aims to examine the effect of a transitional care model, The Transitional Liver Clinic (TLC), in reducing hospital re-admissions, improving quality of life, and improving patient experience.
Gender:
All
Ages:
18 years and above
Trial Updated:
09/19/2023
Locations: University of Chicago, Chicago, Illinois +3 locations
Conditions: Liver Diseases
Genetic Collection Protocol
Recruiting
This study involves the one-time collection of whole blood or saliva samples for the extraction and storage of DNA for use in ongoing and future ChiLDReN studies.
Gender:
All
Ages:
Between 24 hours and 25 years
Trial Updated:
09/12/2023
Locations: Children's Hospital of Los Angeles, Los Angeles, California +12 locations
Conditions: Liver Diseases
Noninvasive Subharmonic Aided Pressure Estimation of Portal Hypertension; Renewal
Recruiting
This is an open-label, non-randomized trial that will be conducted at three clinical sites, Thomas Jefferson University (TJU), the Hospital of the University of Pennsylvania (HUP) and University of Bern (UB). Enrollment will be allocated into one of 4 different cohorts depending on the inclusion criteria for each cohort. Cohort 1: Patients scheduled for hepatic vein pressure gradient (HVPG) measurements will subsequently undergo two consecutive SHAPE (subharmonic aided pressure estimation) pro... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
07/10/2023
Locations: University of Pennsylvania, Philadelphia, Pennsylvania +2 locations
Conditions: Liver Diseases, Portal Hypertension
Social & Contextual Impact on Children Undergoing Liver Transplantation
Recruiting
The social determinants of health have a large impact on health. For example, neighborhood socioeconomic deprivation is associated with increased risk of medication non-adherence, graft failure, and death in children after liver transplant. In order to address these socioeconomic inequities in outcomes, a more granular understanding of how the social determinants of health impact outcomes is needed. In this observational prospective cohort, caregivers of children undergoing liver transplantation... Read More
Gender:
All
Ages:
70 years and below
Trial Updated:
06/26/2023
Locations: Children's Hospital Los Angeles, Los Angeles, California +7 locations
Conditions: Liver Transplantation, Liver Diseases
Treating Pediatric NAFLD With Nutrition
Recruiting
This is a proof of concept clinical trial to compare daily intake of at least 20 grams of whole dairy fat vs habitual diet on hepatic steatosis in children with NAFLD.
Gender:
All
Ages:
Between 10 years and 17 years
Trial Updated:
06/01/2023
Locations: UC San Diego, La Jolla, California
Conditions: Non-Alcoholic Fatty Liver Disease, Liver Diseases, Liver Fat, Hepatic Steatosis, Nutritional and Metabolic Disease
Liver Transplantation in Patients With CirrHosis and Severe Acute-on-Chronic Liver Failure: iNdications and outComEs
Recruiting
Management of ACLF is mainly supportive. The poor outcomes lead physicians to consider liver transplantation as an option, even if controversial. In sicker recipients, LT results in immediate survival, but poor medium-term survival rates in some studies. The scarcity of deceased donors obliges to maximize LT success. Alternative strategies, as living-donor LT, should be explored. LDLT has impressive results in Eastern centers, but it is restrained in Western countries, due to potential life-thre... Read More
Gender:
All
Ages:
Between 18 years and 80 years
Trial Updated:
05/03/2023
Locations: Cedars-Sinai Comprehensive Transplant Center, Los Angeles, California +105 locations
Conditions: Liver Diseases, Liver Cirrhosis, Acute-On-Chronic Liver Failure, Liver Transplant; Complications
MAsS Scan as a Predictor of Morbidity and Mortality in Patients With Liver Disease
Recruiting
The purpose of the study is to study the muscle assessment score (MAsS, utilizing MRI, as an objective measure of frailty and muscle composition to serve as a predictor of morbidity and mortality in patients with liver disease.
Gender:
All
Ages:
18 years and above
Trial Updated:
04/27/2023
Locations: The University of Chicago, Chicago, Illinois
Conditions: Liver Diseases
Observational Pharmaco-Epidemiology Research & Analysis
Recruiting
Greater advances are needed in two separate but related areas in healthcare: 1) the Clinical Decision Support Systems that complement the EHR use in support of routine patient care, population management and disease management; and 2) the use of the point-of-care observational data from the provider-patient encounter that support realworld medical research and healthcare quality measure assessment. Real-world evaluations of treatments of chronic diseases in the context of comorbid conditions and... Read More
Gender:
All
Ages:
0 years and above
Trial Updated:
02/14/2023
Locations: Epividian, Durham, North Carolina
Conditions: Chronic Disease, HIV/AIDS, Liver Diseases, Inflammatory Bowel Diseases, Cardiovascular Diseases, Rheumatic Diseases, Neurodegenerative Diseases
Blood Collection for Development and Validation of Point-of-Care Diagnostic Liver Function Tests
Recruiting
This is an observational study exploring the performance of a novel point-of-care diagnostic testing platform designed to quantitate the presence of liver function biomarkers such as bilirubin. Blood samples will be collected from participants to further development and validation of the testing platform to support FDA review. The diagnostic device is intended to provide rapid in-office test results using a finger stick of blood, a reaction test device, and a smartphone app.
Gender:
All
Ages:
18 years and above
Trial Updated:
07/11/2022
Locations: Group K Diagnostics, Philadelphia, Pennsylvania
Conditions: Liver Diseases, Healthy, Liver Cirrhosis, Liver Fibrosis