Myelodysplastic Syndrome Clinical Trials

A listing of 59 Myelodysplastic Syndrome clinical trials actively recruiting volunteers for paid trials and research studies in various therapeutic areas.

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There are currently 59 active clinical trials seeking participants for Myelodysplastic Syndrome research studies. The states with the highest number of trials for Myelodysplastic Syndrome participants are Illinois, California, Texas and New York.

Featured Trial

Paid Clinical Studies Nationwide

Recruiting

Nationwide clinical trials offered in your area. Some trials offering up to several thousand dollars in compensation for participation.

Conditions:

Healthy

Healthy Volunteer Study

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* Compensation for time may be available

Featured Trial

Chronic Cough Study

Recruiting

Are you tired of living with chronic cough? The ASPIRE Study is now looking to enroll people from all backgrounds to help research potential new treatment options for chronic cough. You are under no obligation to take part and health insurance is not required. Find out more today! We’d love to hear from you.

Conditions:

Chronic Cough

Refractory or Unexplained Chronic Cough

Cough

Asthma

Allergic Asthma

Learn More

Featured Trial

Studying an Investigational Virus Vaccine

Recruiting

The main objectives of this study are to assess the safety and effectiveness of an investigational vaccine aimed at preventing norovirus, commonly known as the stomach flu. Participants will be randomly assigned to receive either the investigational vaccine or a placebo. Should you express interest, you will be contacted directly by the research site, which will provide further details and answer any questions you may have about study requirements, risks/benefits, and any compensation.

Conditions:

Healthy

Interested in vaccine studies

All Conditions

Preventative Trials

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Featured Trial

Type 2 Diabetes Clinical Trial

Recruiting

Can changing your breakfast improve your type 2 diabetes? If you have an HbA1C of 7.0% or higher, you are invited to participate in an online study at the University of Michigan.

Conditions:

Type 2 Diabetes

Diabetes Mellitus Type 2 in Obese

Diabetes Type Two

Type 2 Diabetes Mellitus

Diabete Type 2

Learn More

Collection of Tissue Samples for Cancer Research

NCT00900198

Recruiting

Background: -Patients who are being evaluated and/or treated at the NIH Clinical Center and adult patients at participating sites will be entered onto this tissue procurement protocol for collection of tissue specimens. Objectives: * To obtain samples from adult and pediatric patients for research purposes from tests and procedures that are done as required by the primary research protocol(s) to which a patient is enrolled or as part of their standard-of-care treatment. * To obtain samples for research purposes from non-surgical procedures, such as percutaneous biopsies, performed for the sole purpose of obtaining tissue specimens or biological fluids for this protocol. Eligibility: -Adult patients (18 years of age and older) and pediatric patients (younger than 18 years of age) who are being evaluated for and/or treated for cancer at the NIH Clinical Center participating sites. Design: * This is a multicenter tissue procurement protocol with NCI as the coordinating center. * For adult patients: specimens for research purposes, as outlined in this protocol, will be obtained from tests and procedures that are done as required by the primary research protocols to which a patient is enrolled or as part of their standard-of-care treatment. Non-surgical procedures, such as percutaneous biopsies, may also be performed for the sole purpose of obtaining tissue specimens or biological fluids for this protocol. Tissues and biological fluids to be procured may include but are not limited to blood, serum, urine, tumor tissue, normal tissue, pleural fluid, CSF, saliva, bronchial alveolar lavage (BAL), circulating tumor cells, hair follicles, and bone marrow. These specimens will be stored with unique identifiers and used to perform only those research studies that are outlined in this protocol. * For pediatric patients: tumor biopsy/resection tissue used for pediatric preclinical model development will only be from tissue already being obtained as part of a procedure necessary for the patient s clinical care or as part of a primary research protocol; blood specimens will be collected as part of a blood collection already scheduled for the patient s clinical care or as part of the planned pre-procedure bloodwork; volumes collected will not exceed institutional research limits. * Given the risks associated with any invasive procedure, such as tumor biopsy, the procedure will be discussed in detail with the patients and their parents/guardian (as indicated), including the side effects, prior to obtaining a separate consent for each procedure. A separate consent will not be signed prior to obtaining samples by minimally invasive measures, such as venipuncture. * This study has two separate consent forms at the NIH Clinical Center: one for adult patients to donate specimens for ongoing research on assay development and studies of molecular pathways, and one for adult and age-appropriate pediatric patients to donate samples for the generation of preclinical models. The study also has consent form templates for adult and pediatric patients at participating sites to donate specimens to create preclinical models. * Patients may remain on study for the duration of their consent or completion of the planned procedure, whichever comes first. Read Less

Gender:

ALL

Ages:

2 months and above

Trial Updated:

04/15/2025

Locations: UC Davis, Sacramento, California +16 locations

Conditions: Neoplasms, Lymphomas, Multiple Myeloma, Myelodysplastic Syndrome

Learn More ›

A Safety Study of SEA-CD70 in Patients With Myeloid Malignancies

NCT04227847

Recruiting

This trial will look at a drug called SEA-CD70 with and without azacitidine, to find out if it is safe for participants with myelodysplastic syndrome (MDS) and acute myeloid leukemia (AML). It will study SEA-CD70 to find out what its side effects are and if it works for AML and MDS. A side effect is anything the drug does besides treating cancer. This study will have seven groups or "parts." * Part A will find out how much SEA-CD70 should be given to participants * Part B will use the dose fou... Read More

Gender:

ALL

Ages:

18 years and above

Trial Updated:

04/15/2025

Locations: University of Alabama at Birmingham, Birmingham, Alabama +49 locations

University of Alabama at Birmingham, Birmingham, Alabama

ONeal Comprehensive Cancer Center at UAB, Birmingham, Alabama

City of Hope (City of Hope National Medical Center, City of Hope Medical Center), Duarte, California

IP Address: City of Hope Investigational Drug Services(IDS), Duarte, California

Ronald Reagan UCLA Medical Center, Los Angeles, California

UCLA Department of Medicine - Hematology & Oncology, Los Angeles, California

UCLA Hematology-Oncology Clinic, Los Angeles, California

Colorado Blood Cancer Institute, Lab, Denver, Colorado

Colorado Blood Cancer Institute, Denver, Colorado

Presbyterian/St. Luke's Medical Center, Denver, Colorado

The University of Kansas Cancer Center ,Investigational Drug Services, Fairway, Kansas

The University of Kansas Clinical Research Center, Fairway, Kansas

The University of Kansas Hospital, Kansas City, Kansas

University of Kansas Hospital Cambridge North Tower A, Kansas City, Kansas

University of Kansas Medical center Medical office building, Kansas City, Kansas

The University of Kansas Cancer Center - Overland Park, Overland Park, Kansas

The University of Kansas Cancer Center - Indian Creek Campus, Overland Park, Kansas

Norton Cancer Institute, St. Matthews Campus, Attn. Becky Champion, PharmD, Louisville, Kentucky

Norton Cancer Institute, St. Matthews Campus, Louisville, Kentucky

Norton Women & Children's Hospital, Louisville, Kentucky

Massachusetts General Hospital, Boston, Massachusetts

Beth Israel Deaconess Medical Center, Boston, Massachusetts

Karmanos Cancer Institute, Detroit, Michigan

Karmanos Cancer Institute Weisberg Cancer Treatment Center, Farmington Hills, Michigan

The University of Kansas Cancer Center - Medical Oncology Clinic, Kansas City, Missouri

The University of Kansas Cancer Center - Radiation Oncology Clinic, Kansas City, Missouri

The University of Kansas Cancer Center -North, Kansas City, Missouri

The University of Kansas Cancer Center - Lee's Summit, Lee's Summit, Missouri

San Juan Oncology Associates, Farmington, New Mexico

Columbia University Irving Medical Center, New York, New York

CUIMC Research Pharmacy, New York, New York

University Hospitals Cleveland Medical Center, Cleveland, Ohio

Cleveland Clinic, Cleveland, Ohio

James Cancer Hospital / Ohio State University, Columbus, Ohio

The Ohio State University Wexner Medical Center/James Cancer Hospital, Columbus, Ohio

Hollings Cancer Center, Charleston, South Carolina

Medical University of South Carolina- Ashley River Tower, Charleston, South Carolina

Medical University of South Carolina- Investigational Drug Services, Charleston, South Carolina

Medical University of South Carolina- University Hospital, Charleston, South Carolina

St. Francis Hospital, Greenville, South Carolina

St. Francis Cancer Center, Greenville, South Carolina

Baylor University Medical Center, Investigational Drug Services, Department of Pharmacy, Dallas, Texas

Baylor University Medical Center, Dallas, Texas

Houston Methodist Hospital, Houston, Texas

The University of Texas MD Anderson Cancer Center, Houston, Texas

Swedish Cancer Institute, Seattle, Washington

Swedish Medical Center, Seattle, Washington

Pharmacy - UMC Utrecht t.a.v. Apotheek KGO, Utrecht, Not set

University Medical Center (UMC) Utrecht, Utrecht, Not set

Conditions: Acute Myeloid Leukemia, Myelodysplastic Syndrome

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Testing the Addition of an IDH2 Inhibitor, Enasidenib, to Usual Treatment (Cedazuridine-Decitabine) for Higher-Risk Myelodysplastic Syndrome (MDS) With IDH2 Mutation (A MyeloMATCH Treatment Trial)

NCT06577441

Recruiting

This phase II MyeloMATCH treatment trial compares the usual treatment of cedazuridine-decitabine (ASTX727) to the combination treatment of ASTX727 and enasidenib in treating patients with higher-risk, IDH2-mutated myelodysplastic syndrome (MDS). ASTX727 is a combination of two drugs, decitabine and cedazuridine. Cedazuridine is in a class of medications called cytidine deaminase inhibitors. It prevents the breakdown of decitabine, making it more available in the body so that decitabine will have... Read More

Gender:

ALL

Ages:

18 years and above

Trial Updated:

04/12/2025

Locations: Trinity Health IHA Medical Group Hematology Oncology - Brighton, Brighton, Michigan +8 locations

Conditions: Myelodysplastic Syndrome

Learn More ›

Venetoclax in Combination With ASTX727 for the Treatment of Chronic Myelomonocytic Leukemia and Other Myelodysplastic Syndrome/Myeloproliferative Neoplasm

NCT05600894

Recruiting

This phase II trial tests whether decitabine and cedazuridine (ASTX727) in combination with venetoclax work better than ASTX727 alone at decreasing symptoms of bone marrow cancer in patients with chronic myelomonocytic leukemia (CMML), myelodysplastic syndrome/myeloproliferative neoplasm (MDS/MPN) with excess blasts. Blasts are immature blood cells. Decitabine is in a class of medications called hypomethylation agents. It works by helping the bone marrow produce normal blood cells and by killing... Read More

Gender:

ALL

Ages:

18 years and above

Trial Updated:

04/12/2025

Locations: Mayo Clinic Hospital in Arizona, Phoenix, Arizona +32 locations

Mayo Clinic Hospital in Arizona, Phoenix, Arizona

UC Irvine Health Cancer Center-Newport, Costa Mesa, California

UCI Health - Chao Family Comprehensive Cancer Center and Ambulatory Care, Irvine, California

UCI Health Laguna Hills, Laguna Hills, California

Los Angeles General Medical Center, Los Angeles, California

USC / Norris Comprehensive Cancer Center, Los Angeles, California

UC Irvine Health/Chao Family Comprehensive Cancer Center, Orange, California

University of California Davis Comprehensive Cancer Center, Sacramento, California

Yale University, New Haven, Connecticut

Mayo Clinic in Florida, Jacksonville, Florida

Northwestern University, Chicago, Illinois

University of Chicago Comprehensive Cancer Center, Chicago, Illinois

UC Comprehensive Cancer Center at Silver Cross, New Lenox, Illinois

University of Chicago Medicine-Orland Park, Orland Park, Illinois

University of Kansas Cancer Center, Kansas City, Kansas

University of Kansas Hospital-Westwood Cancer Center, Westwood, Kansas

University of Maryland/Greenebaum Cancer Center, Baltimore, Maryland

Johns Hopkins University/Sidney Kimmel Cancer Center, Baltimore, Maryland

Beth Israel Deaconess Medical Center, Boston, Massachusetts

Montefiore Medical Center-Einstein Campus, Bronx, New York

Montefiore Medical Center-Weiler Hospital, Bronx, New York

Montefiore Medical Center - Moses Campus, Bronx, New York

UNC Lineberger Comprehensive Cancer Center, Chapel Hill, North Carolina

Wake Forest University Health Sciences, Winston-Salem, North Carolina

University of Cincinnati Cancer Center-UC Medical Center, Cincinnati, Ohio

Ohio State University Comprehensive Cancer Center, Columbus, Ohio

University of Cincinnati Cancer Center-West Chester, West Chester, Ohio

University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma

University of Pittsburgh Cancer Institute (UPCI), Pittsburgh, Pennsylvania

Huntsman Cancer Institute/University of Utah, Salt Lake City, Utah

University of Virginia Cancer Center, Charlottesville, Virginia

Virginia Commonwealth University/Massey Cancer Center, Richmond, Virginia

University Health Network-Princess Margaret Hospital, Toronto, Ontario

Conditions: Chronic Myelomonocytic Leukemia, Myelodysplastic Syndrome, Myelodysplastic Syndrome With Excess Blasts, Myeloproliferative Neoplasm, Myelodysplastic/Myeloproliferative Neoplasm

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Study of BMS-986497 (ORM-6151) in Participants With Relapsed or Refractory Acute Myeloid Leukemia or Myelodysplastic Syndrome

NCT06419634

Recruiting

The purpose of this study is to assess the safety, tolerability, drug levels, drug efficacy and determine the recommended dose of BMS-986497 in participants with relapsed or refractory acute myeloid leukemia (AML) or myelodysplastic syndrome (MDS).

Gender:

ALL

Ages:

18 years and above

Trial Updated:

04/11/2025

Locations: Yale-New Haven Hospital, New Haven, Connecticut +10 locations

Conditions: Acute Myeloid Leukemia, Myelodysplastic Syndrome

Learn More ›

Infusion of Expanded Cord Blood Cells in Addition to Single Cord Blood Transplant in Treating Patients With Acute Leukemia, Chronic Myeloid Leukemia, or Myelodysplastic Syndromes

NCT03399773

Recruiting

This phase II trial studies how well donor umbilical cord blood transplant with ex-vivo expanded cord blood progenitor cells (dilanubicel) works in treating patients with blood cancer. Before the transplant, patients will receive chemotherapy (fludarabine, cyclophosphamide and in some cases thiotepa) and radiation therapy. Giving chemotherapy and total-body irradiation before a donor umbilical cord blood transplant helps stop the growth of cells in the bone marrow, including normal blood-forming... Read More

Gender:

ALL

Ages:

Between 10 years and 65 years

Trial Updated:

04/09/2025

Locations: Fred Hutch/University of Washington Cancer Consortium, Seattle, Washington

Conditions: Acute Biphenotypic Leukemia, Acute Lymphoblastic Leukemia, Chronic Myelogenous Leukemia, BCR-ABL1 Positive, Hematopoietic and Lymphoid Cell Neoplasm, Myelodysplastic Syndrome, Myelodysplastic Syndrome With Excess Blasts

Learn More ›

Trial of 2 Step ATG for Prevention of Acute GVHD Post Allogeneic Stem Cell Transplant

NCT06265584

Recruiting

In an effort to reduce graft versus host disease (GVHD) and enhance graft versus leukemia (GVL) effect post allogenic hematopoietic stem cell transplantation (AHSCT), recent research has focused on host immune cell depletion. Frame shifting anti-thymocyte globulin (ATG) backwards to earlier days before days 0 can result in deeper host and less graft T-cell depletion, leading to better immune reconstitution. Preliminary data where 80% of the ATG dose is given on days -6,-5,-4 and 20% given on day... Read More

Gender:

ALL

Ages:

Between 18 years and 75 years

Trial Updated:

04/09/2025

Locations: University of Alabama at Birmingham, Birmingham, Alabama

Conditions: Acute Leukemia, Myelodysplastic Syndrome, Myeloproliferative Disorders

Learn More ›

Azacitidine and Quizartinib for the Treatment of Myelodysplastic Syndrome or Myelodysplastic/Myeloproliferative Neoplasm With FLT3 or CBL Mutations

NCT04493138

Recruiting

This phase I/II trial studies the side effects and best dose of quizartinib when given with azacitidine and to see how well they work in treating patients with myelodysplastic syndrome or myelodysplastic/myeloproliferative neoplasm with FLT3 or CBL mutations. Chemotherapy drugs, such as azacitidine, work in different ways to stop the growth of cancer cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading. Quizartinib may stop the growth of cancer c... Read More

Gender:

ALL

Ages:

18 years and above

Trial Updated:

04/03/2025

Locations: M D Anderson Cancer Center, Houston, Texas

Conditions: Chronic Myelomonocytic Leukemia, Myelodysplastic Syndrome, Myeloproliferative Neoplasm, Recurrent Chronic Myelomonocytic Leukemia, Recurrent Myelodysplastic Syndrome, Recurrent Myeloproliferative Neoplasm

Learn More ›

MYELOMATCH: A Screening Study to Assign People With Myeloid Cancer to a Treatment Study or Standard of Care Treatment Within myeloMATCH (MyeloMATCH Screening Trial)

NCT05564390

Recruiting

This MyeloMATCH Master Screening and Reassessment Protocol (MSRP) evaluates the use of a screening tool and specific laboratory tests to help improve participants' ability to register to clinical trials throughout the course of their myeloid cancer (acute myeloid leukemia or myelodysplastic syndrome) treatment. This study involves testing patients' bone marrow and blood for certain biomarkers. A biomarker (sometimes called a marker) is any molecule in the body that can be measured. Doctors look... Read More

Gender:

ALL

Ages:

18 years and above

Trial Updated:

04/02/2025

Locations: University of Alabama at Birmingham Cancer Center, Birmingham, Alabama +241 locations

University of Alabama at Birmingham Cancer Center, Birmingham, Alabama

Banner University Medical Center - Tucson, Tucson, Arizona

University of Arizona Cancer Center-North Campus, Tucson, Arizona

University of Arkansas for Medical Sciences, Little Rock, Arkansas

Tibor Rubin VA Medical Center, Long Beach, California

Cedars Sinai Medical Center, Los Angeles, California

University of California Davis Comprehensive Cancer Center, Sacramento, California

Yale University, New Haven, Connecticut

Veterans Affairs Connecticut Healthcare System-West Haven Campus, West Haven, Connecticut

Augusta University Medical Center, Augusta, Georgia

Saint Alphonsus Cancer Care Center-Boise, Boise, Idaho

Saint Luke's Cancer Institute - Boise, Boise, Idaho

Saint Alphonsus Cancer Care Center-Caldwell, Caldwell, Idaho

Kootenai Health - Coeur d'Alene, Coeur d'Alene, Idaho

Saint Luke's Cancer Institute - Fruitland, Fruitland, Idaho

Saint Luke's Cancer Institute - Meridian, Meridian, Idaho

Saint Alphonsus Cancer Care Center-Nampa, Nampa, Idaho

Saint Luke's Cancer Institute - Nampa, Nampa, Idaho

Kootenai Clinic Cancer Services - Post Falls, Post Falls, Idaho

Kootenai Clinic Cancer Services - Sandpoint, Sandpoint, Idaho

OSF Saint Joseph Medical Center, Bloomington, Illinois

Illinois CancerCare-Bloomington, Bloomington, Illinois

Illinois CancerCare-Canton, Canton, Illinois

Illinois CancerCare-Carthage, Carthage, Illinois

Northwestern University, Chicago, Illinois

University of Chicago Comprehensive Cancer Center, Chicago, Illinois

Carle at The Riverfront, Danville, Illinois

Cancer Care Specialists of Illinois - Decatur, Decatur, Illinois

Decatur Memorial Hospital, Decatur, Illinois

Northwestern Medicine Cancer Center Kishwaukee, DeKalb, Illinois

Illinois CancerCare-Dixon, Dixon, Illinois

Carle Physician Group-Effingham, Effingham, Illinois

Crossroads Cancer Center, Effingham, Illinois

Illinois CancerCare-Eureka, Eureka, Illinois

NorthShore University HealthSystem-Evanston Hospital, Evanston, Illinois

Illinois CancerCare-Galesburg, Galesburg, Illinois

Northwestern Medicine Cancer Center Delnor, Geneva, Illinois

NorthShore University HealthSystem-Glenbrook Hospital, Glenview, Illinois

Northwestern Medicine Glenview Outpatient Center, Glenview, Illinois

Northwestern Medicine Grayslake Outpatient Center, Grayslake, Illinois

NorthShore University HealthSystem-Highland Park Hospital, Highland Park, Illinois

Illinois CancerCare-Kewanee Clinic, Kewanee, Illinois

Northwestern Medicine Lake Forest Hospital, Lake Forest, Illinois

Illinois CancerCare-Macomb, Macomb, Illinois

Carle Physician Group-Mattoon/Charleston, Mattoon, Illinois

Loyola University Medical Center, Maywood, Illinois

Cancer Care Center of O'Fallon, O'Fallon, Illinois

Northwestern Medicine Orland Park, Orland Park, Illinois

Illinois CancerCare-Ottawa Clinic, Ottawa, Illinois

Illinois CancerCare-Pekin, Pekin, Illinois

Illinois CancerCare-Peoria, Peoria, Illinois

Methodist Medical Center of Illinois, Peoria, Illinois

OSF Saint Francis Medical Center, Peoria, Illinois

Illinois CancerCare-Peru, Peru, Illinois

Illinois CancerCare-Princeton, Princeton, Illinois

Southern Illinois University School of Medicine, Springfield, Illinois

Springfield Clinic, Springfield, Illinois

Springfield Memorial Hospital, Springfield, Illinois

Carle Cancer Center, Urbana, Illinois

Northwestern Medicine Cancer Center Warrenville, Warrenville, Illinois

Illinois CancerCare - Washington, Washington, Illinois

Indiana University/Melvin and Bren Simon Cancer Center, Indianapolis, Indiana

UI Health Care Mission Cancer and Blood - West Des Moines Clinic, Clive, Iowa

Mercy Medical Center - Des Moines, Des Moines, Iowa

UI Health Care Mission Cancer and Blood - Laurel Clinic, Des Moines, Iowa

University of Iowa/Holden Comprehensive Cancer Center, Iowa City, Iowa

University of Kansas Clinical Research Center, Fairway, Kansas

HaysMed, Hays, Kansas

University of Kansas Cancer Center, Kansas City, Kansas

Lawrence Memorial Hospital, Lawrence, Kansas

The University of Kansas Cancer Center - Olathe, Olathe, Kansas

University of Kansas Cancer Center-Overland Park, Overland Park, Kansas

University of Kansas Hospital-Indian Creek Campus, Overland Park, Kansas

Salina Regional Health Center, Salina, Kansas

Cotton O'Neil Cancer Center / Stormont Vail Health, Topeka, Kansas

University of Kansas Health System Saint Francis Campus, Topeka, Kansas

University of Kansas Hospital-Westwood Cancer Center, Westwood, Kansas

University of Kentucky/Markey Cancer Center, Lexington, Kentucky

The James Graham Brown Cancer Center at University of Louisville, Louisville, Kentucky

UofL Health Medical Center Northeast, Louisville, Kentucky

LSU Health Baton Rouge-North Clinic, Baton Rouge, Louisiana

Our Lady of the Lake Physician Group, Baton Rouge, Louisiana

Our Lady of The Lake, Baton Rouge, Louisiana

Mid Coast Hospital, Brunswick, Maine

MaineHealth Cancer Care and IV Therapy - South Portland, South Portland, Maine

Johns Hopkins University/Sidney Kimmel Cancer Center, Baltimore, Maryland

Tufts Medical Center, Boston, Massachusetts

Trinity Health Saint Joseph Mercy Hospital Ann Arbor, Ann Arbor, Michigan

Trinity Health IHA Medical Group Hematology Oncology - Brighton, Brighton, Michigan

Trinity Health IHA Medical Group Hematology Oncology - Canton, Canton, Michigan

Trinity Health IHA Medical Group Hematology Oncology - Chelsea Hospital, Chelsea, Michigan

Wayne State University/Karmanos Cancer Institute, Detroit, Michigan

Henry Ford Hospital, Detroit, Michigan

Weisberg Cancer Treatment Center, Farmington Hills, Michigan

Cancer Hematology Centers - Flint, Flint, Michigan

Genesee Hematology Oncology PC, Flint, Michigan

Genesys Hurley Cancer Institute, Flint, Michigan

Hurley Medical Center, Flint, Michigan

Trinity Health Saint Mary Mercy Livonia Hospital, Livonia, Michigan

Henry Ford Medical Center-Columbus, Novi, Michigan

Henry Ford West Bloomfield Hospital, West Bloomfield, Michigan

Trinity Health IHA Medical Group Hematology Oncology Ann Arbor Campus, Ypsilanti, Michigan

Essentia Health - Deer River Clinic, Deer River, Minnesota

Essentia Health Cancer Center, Duluth, Minnesota

Fairview Southdale Hospital, Edina, Minnesota

Essentia Health Hibbing Clinic, Hibbing, Minnesota

Abbott-Northwestern Hospital, Minneapolis, Minnesota

Park Nicollet Clinic - Saint Louis Park, Saint Louis Park, Minnesota

United Hospital, Saint Paul, Minnesota

Essentia Health Virginia Clinic, Virginia, Minnesota

Baptist Memorial Hospital and Cancer Center-Golden Triangle, Columbus, Mississippi

Baptist Cancer Center-Grenada, Grenada, Mississippi

Baptist Memorial Hospital and Cancer Center-Union County, New Albany, Mississippi

Baptist Memorial Hospital and Cancer Center-Oxford, Oxford, Mississippi

Baptist Memorial Hospital and Cancer Center-Desoto, Southhaven, Mississippi

Siteman Cancer Center at West County Hospital, Creve Coeur, Missouri

University Health Truman Medical Center, Kansas City, Missouri

University of Kansas Cancer Center - North, Kansas City, Missouri

University of Kansas Cancer Center - Lee's Summit, Lee's Summit, Missouri

Heartland Regional Medical Center, Saint Joseph, Missouri

Washington University School of Medicine, Saint Louis, Missouri

Mercy Hospital South, Saint Louis, Missouri

Siteman Cancer Center-South County, Saint Louis, Missouri

Siteman Cancer Center at Christian Hospital, Saint Louis, Missouri

Siteman Cancer Center at Saint Peters Hospital, Saint Peters, Missouri

Billings Clinic Cancer Center, Billings, Montana

Bozeman Health Deaconess Hospital, Bozeman, Montana

Benefis Sletten Cancer Institute, Great Falls, Montana

Logan Health Medical Center, Kalispell, Montana

Saint Patrick Hospital - Community Hospital, Missoula, Montana

Community Medical Center, Missoula, Montana

Nebraska Medicine-Bellevue, Bellevue, Nebraska

Nebraska Medicine-Village Pointe, Omaha, Nebraska

University of Nebraska Medical Center, Omaha, Nebraska

OptumCare Cancer Care at Seven Hills, Henderson, Nevada

OptumCare Cancer Care at Charleston, Las Vegas, Nevada

OptumCare Cancer Care at Fort Apache, Las Vegas, Nevada

Memorial Sloan Kettering Basking Ridge, Basking Ridge, New Jersey

Saint Barnabas Medical Center, Livingston, New Jersey

Monmouth Medical Center, Long Branch, New Jersey

Memorial Sloan Kettering Monmouth, Middletown, New Jersey

Memorial Sloan Kettering Bergen, Montvale, New Jersey

Rutgers Cancer Institute of New Jersey, New Brunswick, New Jersey

Community Medical Center, Toms River, New Jersey

University of New Mexico Cancer Center, Albuquerque, New Mexico

Montefiore Medical Center - Moses Campus, Bronx, New York

Memorial Sloan Kettering Commack, Commack, New York

Northwell Health/Center for Advanced Medicine, Lake Success, New York

North Shore University Hospital, Manhasset, New York

Mount Sinai Hospital, New York, New York

Memorial Sloan Kettering Cancer Center, New York, New York

Rochester General Hospital, Rochester, New York

University of Rochester, Rochester, New York

State University of New York Upstate Medical University, Syracuse, New York

Memorial Sloan Kettering Nassau, Uniondale, New York

UNC Lineberger Comprehensive Cancer Center, Chapel Hill, North Carolina

Duke University Medical Center, Durham, North Carolina

Novant Health Forsyth Medical Center, Winston-Salem, North Carolina

Wake Forest University Health Sciences, Winston-Salem, North Carolina

Case Western Reserve University, Cleveland, Ohio

Ohio State University Comprehensive Cancer Center, Columbus, Ohio

University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma

Providence Newberg Medical Center, Newberg, Oregon

Saint Alphonsus Cancer Care Center-Ontario, Ontario, Oregon

Providence Willamette Falls Medical Center, Oregon City, Oregon

Providence Portland Medical Center, Portland, Oregon

Providence Saint Vincent Medical Center, Portland, Oregon

Oregon Health and Science University, Portland, Oregon

Lehigh Valley Hospital-Cedar Crest, Allentown, Pennsylvania

Geisinger Medical Center, Danville, Pennsylvania

University of Pennsylvania/Abramson Cancer Center, Philadelphia, Pennsylvania

Thomas Jefferson University Hospital, Philadelphia, Pennsylvania

University of Pittsburgh Cancer Institute (UPCI), Pittsburgh, Pennsylvania

Reading Hospital, West Reading, Pennsylvania

Geisinger Wyoming Valley/Henry Cancer Center, Wilkes-Barre, Pennsylvania

Rhode Island Hospital, Providence, Rhode Island

Prisma Health Cancer Institute - Spartanburg, Boiling Springs, South Carolina

Prisma Health Cancer Institute - Easley, Easley, South Carolina

Prisma Health Cancer Institute - Butternut, Greenville, South Carolina

Prisma Health Cancer Institute - Faris, Greenville, South Carolina

Prisma Health Cancer Institute - Eastside, Greenville, South Carolina

Prisma Health Cancer Institute - Greer, Greer, South Carolina

Prisma Health Cancer Institute - Seneca, Seneca, South Carolina

Sanford Cancer Center Oncology Clinic, Sioux Falls, South Dakota

Sanford USD Medical Center - Sioux Falls, Sioux Falls, South Dakota

Baptist Memorial Hospital and Cancer Center-Collierville, Collierville, Tennessee

Baptist Memorial Hospital and Cancer Center-Memphis, Memphis, Tennessee

Huntsman Cancer Institute/University of Utah, Salt Lake City, Utah

George E Wahlen Department of Veterans Affairs Medical Center, Salt Lake City, Utah

University of Virginia Cancer Center, Charlottesville, Virginia

Inova Schar Cancer Institute, Fairfax, Virginia

Inova Fairfax Hospital, Falls Church, Virginia

Virginia Commonwealth University/Massey Cancer Center, Richmond, Virginia

Swedish Cancer Institute-Edmonds, Edmonds, Washington

Swedish Cancer Institute-Issaquah, Issaquah, Washington

Swedish Medical Center-First Hill, Seattle, Washington

ThedaCare Regional Cancer Center, Appleton, Wisconsin

Duluth Clinic Ashland, Ashland, Wisconsin

Aurora Cancer Care-Southern Lakes VLCC, Burlington, Wisconsin

Aurora Saint Luke's South Shore, Cudahy, Wisconsin

Marshfield Medical Center-EC Cancer Center, Eau Claire, Wisconsin

Aurora Health Care Germantown Health Center, Germantown, Wisconsin

Aurora Cancer Care-Grafton, Grafton, Wisconsin

Saint Vincent Hospital Cancer Center Green Bay, Green Bay, Wisconsin

Saint Vincent Hospital Cancer Center at Saint Mary's, Green Bay, Wisconsin

Aurora BayCare Medical Center, Green Bay, Wisconsin

Aurora Cancer Care-Kenosha South, Kenosha, Wisconsin

Gundersen Lutheran Medical Center, La Crosse, Wisconsin

William S Middleton VA Medical Center, Madison, Wisconsin

University of Wisconsin Carbone Cancer Center - Eastpark Medical Center, Madison, Wisconsin

University of Wisconsin Carbone Cancer Center - University Hospital, Madison, Wisconsin

Aurora Bay Area Medical Group-Marinette, Marinette, Wisconsin

Marshfield Medical Center-Marshfield, Marshfield, Wisconsin

Aurora Cancer Care-Milwaukee, Milwaukee, Wisconsin

Aurora Saint Luke's Medical Center, Milwaukee, Wisconsin

Medical College of Wisconsin, Milwaukee, Wisconsin

Aurora Sinai Medical Center, Milwaukee, Wisconsin

Marshfield Medical Center - Minocqua, Minocqua, Wisconsin

ProHealth D N Greenwald Center, Mukwonago, Wisconsin

ProHealth Oconomowoc Memorial Hospital, Oconomowoc, Wisconsin

Saint Vincent Hospital Cancer Center at Oconto Falls, Oconto Falls, Wisconsin

Vince Lombardi Cancer Clinic - Oshkosh, Oshkosh, Wisconsin

Aurora Cancer Care-Racine, Racine, Wisconsin

Marshfield Medical Center-Rice Lake, Rice Lake, Wisconsin

Saint Vincent Hospital Cancer Center at Sheboygan, Sheboygan, Wisconsin

Vince Lombardi Cancer Clinic-Sheboygan, Sheboygan, Wisconsin

Marshfield Medical Center-River Region at Stevens Point, Stevens Point, Wisconsin

Saint Vincent Hospital Cancer Center at Sturgeon Bay, Sturgeon Bay, Wisconsin

Aurora Medical Center in Summit, Summit, Wisconsin

Vince Lombardi Cancer Clinic-Two Rivers, Two Rivers, Wisconsin

ProHealth Waukesha Memorial Hospital, Waukesha, Wisconsin

UW Cancer Center at ProHealth Care, Waukesha, Wisconsin

Aurora Cancer Care-Milwaukee West, Wauwatosa, Wisconsin

Aurora West Allis Medical Center, West Allis, Wisconsin

Marshfield Medical Center - Weston, Weston, Wisconsin

Arthur J E Child Comprehensive Cancer Centre, Calgary, Alberta

CancerCare Manitoba, Winnipeg, Manitoba

CSSS Champlain-Charles Le Moyne, Greenfield Park, Quebec

CIUSSSEMTL-Hopital Maisonneuve-Rosemont, Montreal, Quebec

Jewish General Hospital, Montreal, Quebec

Centro Comprensivo de Cancer de UPR, San Juan, Not set

San Juan City Hospital, San Juan, Not set

Conditions: Acute Myeloid Leukemia, Myelodysplastic Syndrome

Learn More ›

Quizartinib, Decitabine, and Venetoclax in Treating Participants With Untreated or Relapsed Acute Myeloid Leukemia or High Risk Myelodysplastic Syndrome

NCT03661307

Recruiting

This phase I/II trial studies how well quizartinib, decitabine, and venetoclax work in treating participants with acute myeloid leukemia or high risk myelodysplastic syndrome that is untreated or has come back (relapsed). Quizartinib may stop the growth of cancer cells by blocking some of the enzymes needed for cell growth. Drugs used in chemotherapy, such as decitabine and venetoclax, work in different ways to stop the growth of cancer cells, either by killing the cells, by stopping them from d... Read More

Gender:

ALL

Ages:

18 years and above

Trial Updated:

03/28/2025

Locations: M D Anderson Cancer Center, Houston, Texas

Conditions: Acute Myeloid Leukemia, Myelodysplastic Syndrome, Recurrent Acute Myeloid Leukemia, Recurrent Myelodysplastic Syndrome, Refractory Acute Myeloid Leukemia

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A Phase Ib Study of Rezatapopt in Combination With Azacitidine in Patients With TP53Y220C Mutant Myeloid Malignancies (Acute Myeloid Leukemia or Myelodysplastic Syndrome)

NCT06616636

Recruiting

A non-randomized phase Ib study of PC14586 (PMV therapeutics) in patients diagnosed with TP53Y220C-mutant myeloid malignancies, including AML and MDS.

Gender:

ALL

Ages:

18 years and above

Trial Updated:

03/28/2025

Locations: The University of Texas MD Anderson Cancer Center, Houston, Texas

Conditions: Myelodysplastic Syndrome, Acute Myeloid Leukemia

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The Pediatric Acute Leukemia (PedAL) Screening Trial - A Study to Test Bone Marrow and Blood in Children With Leukemia That Has Come Back After Treatment or Is Difficult to Treat - A Leukemia & Lymphoma Society and Children's Oncology Group Study

NCT04726241

Recruiting

This study aims to use clinical and biological characteristics of acute leukemias to screen for patient eligibility for available pediatric leukemia sub-trials. Testing bone marrow and blood from patients with leukemia that has come back after treatment or is difficult to treat may provide information about the patient's leukemia that is important when deciding how to best treat it, and may help doctors find better ways to diagnose and treat leukemia in children, adolescents, and young adults.

Gender:

ALL

Ages:

22 years and below

Trial Updated:

03/25/2025

Locations: Children's Hospital of Alabama, Birmingham, Alabama +176 locations

Children's Hospital of Alabama, Birmingham, Alabama

USA Health Strada Patient Care Center, Mobile, Alabama

Providence Alaska Medical Center, Anchorage, Alaska

Banner Children's at Desert, Mesa, Arizona

Phoenix Childrens Hospital, Phoenix, Arizona

Banner University Medical Center - Tucson, Tucson, Arizona

Arkansas Children's Hospital, Little Rock, Arkansas

Kaiser Permanente Downey Medical Center, Downey, California

Loma Linda University Medical Center, Loma Linda, California

Miller Children's and Women's Hospital Long Beach, Long Beach, California

Children's Hospital Los Angeles, Los Angeles, California

Valley Children's Hospital, Madera, California

UCSF Benioff Children's Hospital Oakland, Oakland, California

Kaiser Permanente-Oakland, Oakland, California

Children's Hospital of Orange County, Orange, California

Lucile Packard Children's Hospital Stanford University, Palo Alto, California

Rady Children's Hospital - San Diego, San Diego, California

UCSF Medical Center-Mission Bay, San Francisco, California

Children's Hospital Colorado, Aurora, Colorado

Rocky Mountain Hospital for Children-Presbyterian Saint Luke's Medical Center, Denver, Colorado

Connecticut Children's Medical Center, Hartford, Connecticut

Yale University, New Haven, Connecticut

Alfred I duPont Hospital for Children, Wilmington, Delaware

MedStar Georgetown University Hospital, Washington, District of Columbia

Children's National Medical Center, Washington, District of Columbia

Broward Health Medical Center, Fort Lauderdale, Florida

Golisano Children's Hospital of Southwest Florida, Fort Myers, Florida

University of Florida Health Science Center - Gainesville, Gainesville, Florida

Memorial Regional Hospital/Joe DiMaggio Children's Hospital, Hollywood, Florida

Nemours Children's Clinic-Jacksonville, Jacksonville, Florida

Nicklaus Children's Hospital, Miami, Florida

Nemours Children's Hospital, Orlando, Florida

Sacred Heart Hospital, Pensacola, Florida

Johns Hopkins All Children's Hospital, Saint Petersburg, Florida

Saint Joseph's Hospital/Children's Hospital-Tampa, Tampa, Florida

Saint Mary's Medical Center, West Palm Beach, Florida

Children's Healthcare of Atlanta - Arthur M Blank Hospital, Atlanta, Georgia

Memorial Health University Medical Center, Savannah, Georgia

Kapiolani Medical Center for Women and Children, Honolulu, Hawaii

Saint Luke's Cancer Institute - Boise, Boise, Idaho

Lurie Children's Hospital-Chicago, Chicago, Illinois

University of Illinois, Chicago, Illinois

University of Chicago Comprehensive Cancer Center, Chicago, Illinois

Loyola University Medical Center, Maywood, Illinois

Advocate Children's Hospital-Park Ridge, Park Ridge, Illinois

Saint Jude Midwest Affiliate, Peoria, Illinois

Southern Illinois University School of Medicine, Springfield, Illinois

Riley Hospital for Children, Indianapolis, Indiana

Ascension Saint Vincent Indianapolis Hospital, Indianapolis, Indiana

Blank Children's Hospital, Des Moines, Iowa

University of Iowa/Holden Comprehensive Cancer Center, Iowa City, Iowa

University of Kentucky/Markey Cancer Center, Lexington, Kentucky

Norton Children's Hospital, Louisville, Kentucky

Children's Hospital New Orleans, New Orleans, Louisiana

Ochsner Medical Center Jefferson, New Orleans, Louisiana

Maine Children's Cancer Program, Scarborough, Maine

Sinai Hospital of Baltimore, Baltimore, Maryland

Johns Hopkins University/Sidney Kimmel Cancer Center, Baltimore, Maryland

Walter Reed National Military Medical Center, Bethesda, Maryland

Dana-Farber Cancer Institute, Boston, Massachusetts

C S Mott Children's Hospital, Ann Arbor, Michigan

Children's Hospital of Michigan, Detroit, Michigan

Michigan State University Clinical Center, East Lansing, Michigan

Corewell Health Grand Rapids Hospitals - Helen DeVos Children's Hospital, Grand Rapids, Michigan

Bronson Methodist Hospital, Kalamazoo, Michigan

Corewell Health Children's, Royal Oak, Michigan

Children's Hospitals and Clinics of Minnesota - Minneapolis, Minneapolis, Minnesota

University of Minnesota/Masonic Cancer Center, Minneapolis, Minnesota

Mayo Clinic in Rochester, Rochester, Minnesota

University of Mississippi Medical Center, Jackson, Mississippi

University of Missouri Children's Hospital, Columbia, Missouri

Children's Mercy Hospitals and Clinics, Kansas City, Missouri

Cardinal Glennon Children's Medical Center, Saint Louis, Missouri

Washington University School of Medicine, Saint Louis, Missouri

Mercy Hospital Saint Louis, Saint Louis, Missouri

Children's Hospital and Medical Center of Omaha, Omaha, Nebraska

University of Nebraska Medical Center, Omaha, Nebraska

Alliance for Childhood Diseases/Cure 4 the Kids Foundation, Las Vegas, Nevada

Summerlin Hospital Medical Center, Las Vegas, Nevada

Renown Regional Medical Center, Reno, Nevada

Dartmouth Hitchcock Medical Center/Dartmouth Cancer Center, Lebanon, New Hampshire

Hackensack University Medical Center, Hackensack, New Jersey

Morristown Medical Center, Morristown, New Jersey

Saint Peter's University Hospital, New Brunswick, New Jersey

Rutgers Cancer Institute of New Jersey-Robert Wood Johnson University Hospital, New Brunswick, New Jersey

Saint Joseph's Regional Medical Center, Paterson, New Jersey

University of New Mexico Cancer Center, Albuquerque, New Mexico

Albany Medical Center, Albany, New York

Montefiore Medical Center - Moses Campus, Bronx, New York

Maimonides Medical Center, Brooklyn, New York

NYU Langone Hospital - Long Island, Mineola, New York

The Steven and Alexandra Cohen Children's Medical Center of New York, New Hyde Park, New York

Laura and Isaac Perlmutter Cancer Center at NYU Langone, New York, New York

NYP/Columbia University Medical Center/Herbert Irving Comprehensive Cancer Center, New York, New York

Memorial Sloan Kettering Cancer Center, New York, New York

University of Rochester, Rochester, New York

Stony Brook University Medical Center, Stony Brook, New York

State University of New York Upstate Medical University, Syracuse, New York

New York Medical College, Valhalla, New York

Mission Hospital, Asheville, North Carolina

UNC Lineberger Comprehensive Cancer Center, Chapel Hill, North Carolina

Carolinas Medical Center/Levine Cancer Institute, Charlotte, North Carolina

Novant Health Presbyterian Medical Center, Charlotte, North Carolina

Duke University Medical Center, Durham, North Carolina

East Carolina University, Greenville, North Carolina

Wake Forest University Health Sciences, Winston-Salem, North Carolina

Sanford Broadway Medical Center, Fargo, North Dakota

Children's Hospital Medical Center of Akron, Akron, Ohio

Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio

Rainbow Babies and Childrens Hospital, Cleveland, Ohio

Cleveland Clinic Foundation, Cleveland, Ohio

Nationwide Children's Hospital, Columbus, Ohio

Dayton Children's Hospital, Dayton, Ohio

ProMedica Toledo Hospital/Russell J Ebeid Children's Hospital, Toledo, Ohio

University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma

Legacy Emanuel Children's Hospital, Portland, Oregon

Oregon Health and Science University, Portland, Oregon

Lehigh Valley Hospital-Cedar Crest, Allentown, Pennsylvania

Geisinger Medical Center, Danville, Pennsylvania

Penn State Children's Hospital, Hershey, Pennsylvania

Children's Hospital of Philadelphia, Philadelphia, Pennsylvania

Saint Christopher's Hospital for Children, Philadelphia, Pennsylvania

Children's Hospital of Pittsburgh of UPMC, Pittsburgh, Pennsylvania

Rhode Island Hospital, Providence, Rhode Island

Medical University of South Carolina, Charleston, South Carolina

Prisma Health Richland Hospital, Columbia, South Carolina

BI-LO Charities Children's Cancer Center, Greenville, South Carolina

Sanford USD Medical Center - Sioux Falls, Sioux Falls, South Dakota

East Tennessee Childrens Hospital, Knoxville, Tennessee

Saint Jude Children's Research Hospital, Memphis, Tennessee

The Children's Hospital at TriStar Centennial, Nashville, Tennessee

Vanderbilt University/Ingram Cancer Center, Nashville, Tennessee

Dell Children's Medical Center of Central Texas, Austin, Texas

Driscoll Children's Hospital, Corpus Christi, Texas

Medical City Dallas Hospital, Dallas, Texas

UT Southwestern/Simmons Cancer Center-Dallas, Dallas, Texas

El Paso Children's Hospital, El Paso, Texas

Cook Children's Medical Center, Fort Worth, Texas

Baylor College of Medicine/Dan L Duncan Comprehensive Cancer Center, Houston, Texas

M D Anderson Cancer Center, Houston, Texas

Covenant Children's Hospital, Lubbock, Texas

UMC Cancer Center / UMC Health System, Lubbock, Texas

Children's Hospital of San Antonio, San Antonio, Texas

Methodist Children's Hospital of South Texas, San Antonio, Texas

University of Texas Health Science Center at San Antonio, San Antonio, Texas

Primary Children's Hospital, Salt Lake City, Utah

University of Virginia Cancer Center, Charlottesville, Virginia

Inova Fairfax Hospital, Falls Church, Virginia

Children's Hospital of The King's Daughters, Norfolk, Virginia

Virginia Commonwealth University/Massey Cancer Center, Richmond, Virginia

Carilion Children's, Roanoke, Virginia

Seattle Children's Hospital, Seattle, Washington

Providence Sacred Heart Medical Center and Children's Hospital, Spokane, Washington

Mary Bridge Children's Hospital and Health Center, Tacoma, Washington

Madigan Army Medical Center, Tacoma, Washington

West Virginia University Healthcare, Morgantown, West Virginia

University of Wisconsin Carbone Cancer Center - University Hospital, Madison, Wisconsin

Marshfield Medical Center-Marshfield, Marshfield, Wisconsin

The Children's Hospital at Westmead, Westmead, New South Wales

Queensland Children's Hospital, South Brisbane, Queensland

Royal Children's Hospital, Parkville, Victoria

Perth Children's Hospital, Perth, Western Australia

Alberta Children's Hospital, Calgary, Alberta

University of Alberta Hospital, Edmonton, Alberta

British Columbia Children's Hospital, Vancouver, British Columbia

CancerCare Manitoba, Winnipeg, Manitoba

IWK Health Centre, Halifax, Nova Scotia

Children's Hospital, London, Ontario

Children's Hospital of Eastern Ontario, Ottawa, Ontario

Hospital for Sick Children, Toronto, Ontario

The Montreal Children's Hospital of the MUHC, Montreal, Quebec

Centre Hospitalier Universitaire Sainte-Justine, Montreal, Quebec

Centre Hospitalier Universitaire de Sherbrooke-Fleurimont, Sherbrooke, Quebec

CHU de Quebec-Centre Hospitalier de l'Universite Laval (CHUL), Quebec, Not set

Starship Children's Hospital, Grafton, Auckland

Christchurch Hospital, Christchurch, Not set

HIMA San Pablo Oncologic Hospital, Caguas, Not set

Conditions: Acute Lymphoblastic Leukemia, Acute Myeloid Leukemia, Acute Myeloid Leukemia Post Cytotoxic Therapy, Juvenile Myelomonocytic Leukemia, Mixed Phenotype Acute Leukemia, Myelodysplastic Syndrome, Myelodysplastic Syndrome Post Cytotoxic Therapy, Myeloid Leukemia Associated With Down Syndrome

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