There are currently 18 active clinical trials seeking participants for Pneumonia research studies. The states with the highest number of trials for Pneumonia participants are California, Texas, Florida and Ohio.
Ceftriaxone to PRevent pneumOnia and inflammatTion aftEr Cardiac arresT (PROTECT)
Recruiting
Randomized-controlled trial and microbiome assessment to understand the risk-to-benefit ratio of prophylactic antibiotics (Ceftriaxone) vs placebo in patients with pneumonia and inflammation after cardiac arrest outside the hospital.
Gender:
All
Ages:
18 years and above
Trial Updated:
10/02/2023
Locations: Maine Medical Center, Portland, Maine
Conditions: Out-Of-Hospital Cardiac Arrest, Pneumonia
Phase 2a Multiple Ascending Dose Study in Hospitalized Patients With Pneumonia.
Recruiting
A Phase 2a, randomized, double-blind, placebo-controlled, multiple ascending dose study in patients who are hospitalized with presumed pneumonia requiring supplemental oxygen therapy. The purpose of this study is to examine the safety, tolerability and efficacy of AV-001 Injection administration daily to the earlier of day 28 or EOT (day prior to hospital discharge). A total of 120 eligible patients (20 patients in each of cohort 1, 2 and 3 and 60 patients in cohort 4) will be recruited from up... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
09/27/2023
Locations: Hoag Memorial Hospital Presbyterian, Newport Beach, California +6 locations
Conditions: Acute Respiratory Distress Syndrome, COVID-19 Acute Respiratory Distress Syndrome, Viral or Bacterial Infections, Pneumonia, Pneumonia, Viral, Respiratory Infection
A Vaccine (CIMAvax-EGF) for the Prevention of Lung Cancer Development or Recurrence
Recruiting
This early phase I trial studies the side effects of a vaccine called CIMAvax-EGF and to see how well it works in preventing lung cancer from developing in patients at high risk for lung cancer or coming back (recurrence) in stage IB-IIIA non-small cell lung cancer survivors. In many cancers such as lung cancer, there is a protein receptor called EGFR (epidermal growth factor receptor) that is overexpressed within these cancers. Activation of EGFR has shown to lead to tumor growth and developmen... Read More
Gender:
All
Ages:
Between 50 years and 79 years
Trial Updated:
07/28/2023
Locations: Roswell Park Cancer Institute, Buffalo, New York
Conditions: Chronic Obstructive Pulmonary Disease, Lung Non-Small Cell Carcinoma, Pneumonia, Stage IB Lung Cancer AJCC v8, Stage II Lung Cancer AJCC v8, Stage IIA Lung Cancer AJCC v8, Stage IIB Lung Cancer AJCC v8, Stage IIIA Lung Cancer AJCC v8
Comparative Effectiveness of Readmission Reduction Interventions for Individuals With Sepsis or Pneumonia
Recruiting
An adaptive platform trial to compare effectiveness of different care models to prevent readmissions for patients hospitalized with sepsis or lower respiratory tract infection. The primary outcome is number of days spent at home within 90 days after hospital discharge.
Gender:
All
Ages:
21 years and above
Trial Updated:
07/26/2023
Locations: UPMC Presbyterian, Pittsburgh, Pennsylvania
Conditions: Sepsis, Pneumonia, Lower Resp Tract Infection, Covid19
ARrest RESpiraTory Failure From PNEUMONIA
Recruiting
This research study seeks to establish the effectiveness of a combination of an inhaled corticosteroid and a beta agonist compared to placebo for the prevention of acute respiratory failure (ARF) in hospitalized patients with pneumonia and hypoxemia.
Gender:
All
Ages:
18 years and above
Trial Updated:
06/26/2023
Locations: University of Alabama-Birmingham, Birmingham, Alabama +11 locations
Conditions: Pneumonia, Hypoxemia, Acute Respiratory Failure, COVID-19 Pneumonia
Validation of Aspiration Markers in Intubated Patients
Recruiting
The goal of this interventional study is to test Quinine as marker of aspiration (endotracheal tube [ETT] cuff leakage) in mechanically ventilated, critically ill patients.
Gender:
All
Ages:
18 years and above
Trial Updated:
11/08/2022
Locations: Massachussets General Hospital, Boston, Massachusetts
Conditions: Pneumonia, Aspiration