There are currently 18 active clinical trials seeking participants for Pneumonia research studies. The states with the highest number of trials for Pneumonia participants are California, Texas, Florida and Ohio.
Performance of New Diagnostic Methods in Older Adults With Pneumonia
NCT06092008
Recruiting
Create a clinical diagnostic pathway for older ED adults with pneumonia and its subgroups (bacterial, viral, and co-infection) and determine whether novel biomarkers improve diagnostic accuracy. The investigators will conduct a prospective observational trial of 250 ED patients ≥65 years old with suspected pneumonia. The investigators will perform analyses overall and by subgroups, seeking common models to ease adoption.
Gender:
All
Ages:
65 years and above
Trial Updated:
10/17/2023
Locations: The Ohio State University, Columbus, Ohio
Conditions: Pneumonia
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A Study to Learn About How 20-Valent Pneumococcal Conjugate Vaccine Works in a Real-world Setting
NCT05452941
Recruiting
The purpose of this study is to learn about how well the 20-valent pneumococcal conjugate vaccine (20vPnC) works against radiologically-confirmed community-acquired pneumonia (RAD+CAP) due to the 7 new serotypes (types of a bacteria called Streptococcus pneumoniae that cause pneumonia) included in 20vPnC vaccine. This study is seeking participants who: are male or female ≥65 years of age. are hospitalized with physician suspicion of community acquired pneumonia (CAP). have pneumonia confirmed... Read More
Gender:
All
Ages:
65 years and above
Trial Updated:
06/12/2024
Locations: Kaiser Permanete Baldwin Park, Baldwin Park, California +81 locations
Conditions: Pneumonia
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Natural History, Management, and Genetics of the Hyperimmunoglobulin E Recurrent Infection Syndrome (HIES)
NCT00006150
Recruiting
The Hyper IgE Syndromes (HIES) are primary immunodeficiencies resulting in eczema and recurrent skin and lung infections. Autosomal dominant Hyper IgE syndrome (AD-HIIES; Job's syndrome) is caused by STAT3 mutations, and is a multi-system disorder with skeletal, vascular, and connective tissue manifestations. Understanding how STAT3 mutations cause these diverse clinical manifestations is critical to our complete understanding of bone metabolism, bronchiectasis, dental maturation, and atheroscle... Read More
Gender:
All
Ages:
Between 1 month and 120 years
Trial Updated:
06/06/2024
Locations: National Institutes of Health Clinical Center, Bethesda, Maryland
Conditions: Immune System Diseases, STAT3 Transcription Factor, Job Syndrome, Infections, Pneumonia
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Study of Lung Proteins in Patients With Pneumonia
NCT00077909
Recruiting
This study will examine the different types of proteins present in the lungs of patients with pneumonia to explore the causes of different types of the disease. Pneumonia is a condition that causes lung inflammation AND is often caused by an infection. It is usually diagnosed by lung x-rays and listening to the chest with a stethoscope. This method can diagnose pneumonia, but it does not provide information on the cause of the inflammation - information that might be helpful in guiding treatment... Read More
Gender:
All
Ages:
Between 3 years and 99 years
Trial Updated:
06/06/2024
Locations: National Institutes of Health Clinical Center, Bethesda, Maryland
Conditions: Pneumonia, Pulmonary Disease, Lung Disease
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Ceftolozane-Tazobactam for Directed Treatment of Pseudomonas Aeruginosa Bacteremia and Pneumonia in Patients With Hematological Malignancies and Hematopoietic Stem Cell Transplantation
NCT04673175
Recruiting
This is an open-label study, where participants will be given ceftolozane-tazobactam as the primary treatment for Pseudomonas aeruginosa infections. Open-label means both the investigator and the participant will known what drug will be given. Participants will be followed for approximately 60 days. Ceftolozane-tazobactam is approved by the Food and Drug Administration (FDA) for treatment of serious bacterial infection and the investigator hypothesizes that ceftolozane/tazobactam may be effectiv... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
04/30/2024
Locations: Weill Cornell Medicine, New York, New York
Conditions: Pseudomonas Aeruginosa, Pneumonia, Hematologic Malignancy
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The Role of Circadian Clock Proteins in Innate and Adaptive Immunity
NCT03482245
Recruiting
Our data suggest that modulating the characteristics of light carries the potential to modify the host response to injury and critical illness and thus, improve outcome. The ability to modify the host response to the stress of major operations and sepsis carries immense potential to improve patient care. The primary purpose of this study is to determine if exposure to bright blue (442nm) enriched light, by comparison to ambient white fluorescent light, reduces the inflammatory response or organ... Read More
Gender:
All
Ages:
Between 18 years and 65 years
Trial Updated:
04/15/2024
Locations: Barnes Jewish Hospital, Saint Louis, Missouri
Conditions: Pneumonia, Necrotizing Soft Tissue Infection, Infection Joint, Intraabdominal Infections
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Follow-up Automatically vs. As-Needed Comparison (FAAN-C) Trial
NCT05471908
Recruiting
Compare the effectiveness of automatic vs as-needed (PRN) post-hospitalization follow-up for children who are hospitalized for common infections.
Gender:
All
Ages:
18 years and below
Trial Updated:
04/04/2024
Locations: Phoenix Children's Hospital, Phoenix, Arizona +12 locations
Conditions: Pneumonia, Urinary Tract Infections, Soft Tissue Infections, Gastroenteritis
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Pharmacokinetics, Pharmacodynamics, and Safety Profile of Understudied Drugs Administered to Children Per Standard of Care (POPS)
NCT04278404
Recruiting
The study investigators are interested in learning more about how drugs, that are given to children by their health care provider, act in the bodies of children and young adults in hopes to find the most safe and effective dose for children. The primary objective of this study is to evaluate the PK of understudied drugs currently being administered to children per SOC as prescribed by their treating provider.
Gender:
All
Ages:
Between 0 years and 20 years
Trial Updated:
03/29/2024
Locations: Phoenix Children's Hospital, Phoenix, Arizona +51 locations
Conditions: Coronavirus Infection (COVID-19), Pulmonary Arterial Hypertension, Urinary Tract Infections in Children, Hypertension, Pain, Hyperphosphatemia, Primary Hyperaldosteronism, Edema, Hypokalemia, Heart Failure, Menorrhagia, Insomnia, Pneumonia, Skin Infection, Arrythmia, Asthma in Children, Bronchopulmonary Dysplasia, Adrenal Insufficiency, Fibrinolysis; Hemorrhage, Hemophilia, Attention Deficit Hyperactivity Disorder, Multisystem Inflammatory Syndrome in Children (MIS-C), Kawasaki Disease, Coagulation Disorder, Down Syndrome
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Using Probability of Community-Acquired Pneumonia to Tailor Antimicrobials Among Inpatients
NCT05976581
Recruiting
The goal of this prospective randomized study is to improve antibiotic use among hospitalized patients with suspected pneumonia. An alert was built into the electronic health record to guide use of diagnostic testing based on probability of bacterial pneumonia. Patients with test results suggesting viral infection will be randomized to either: (1) receive a structured communication from the antimicrobial stewardship team to de-escalate antibiotics or (2) usual care.
Gender:
All
Ages:
18 years and above
Trial Updated:
02/18/2024
Locations: University of Maryland Medical Center - Midtown Campus, Baltimore, Maryland +1 locations
Conditions: Pneumonia, Pneumonia, Viral, Pneumonia, Bacterial
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Hyperpolarized 129-Xenon Imaging in Adult Hematopoietic Cell Transplant Recipients With Pulmonary Impairment
NCT05041140
Recruiting
This study is designed to measure the correlation of hyperpolarized 129-Xe magnetic resonance imaging (129-XeMRI) in allogeneic hematopoietic cell transplant (allo-HCT) recipients at MD Anderson Cancer Center (MDACC) who develop bronchiolitis obliterans syndrome (BOS) or BOS stage 0p (pulmonary impairment not meeting the definition for BOS, defined below) and controls with chronic graft-versus-host disease (cGVHD). The primary objective of the study is to correlate 129-Xenon measures of ventila... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
02/07/2024
Locations: M D Anderson Cancer Center, Houston, Texas
Conditions: Pulmonary, Pneumonia, Hematopoietic System--Cancer
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A Study To Learn About The Effects Of Pneumococcal Vaccine In People With HIV
NCT05794191
Recruiting
The purpose of this study is to learn about how well a vaccine (Prevnar 13, PCV13) works in preventing disease in adults with HIV. The diseases studied are pneumonia. Mostly the ones caused by the bacteria - pneumococcus. This study also evaluates the type of pneumonia that is spread into the bloodstream. All participants in the study will be identified in health care databases. Adults with HIV will be identified by looking for a medical diagnosis that has confirmed HIV from the databases. Vac... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
12/21/2023
Locations: Pfizer, New York, New York
Conditions: HIV, Pneumonia, Infections, Pneumococcal
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Simultaneously Implementing Pathways for Improving Asthma, Pneumonia, and Bronchiolitis Care for Hospitalized Children
NCT05206695
Recruiting
This study's objective is to identify and test pragmatic and sustainable strategies for implementing a multi-condition clinical pathway intervention for children hospitalized with asthma, pneumonia, or bronchiolitis in community hospitals. The hypothesis is that the multi-condition pathway intervention will be associated with significantly greater increases in clinicians' adoption of evidence-based practices compared to control. The study is a pragmatic, cluster-randomized trial in US community... Read More
Gender:
All
Ages:
17 years and below
Trial Updated:
10/12/2023
Locations: University of California, San Francisco, San Francisco, California
Conditions: Asthma, Pneumonia, Bronchiolitis
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