There are currently 22 active clinical trials seeking participants for Pneumonia research studies. The states with the highest number of trials for Pneumonia participants are California, Texas, Florida and Ohio.
Performance of New Diagnostic Methods in Older Adults With Pneumonia
NCT06092008
Recruiting
Create a clinical diagnostic pathway for older ED adults with pneumonia and its subgroups (bacterial, viral, and co-infection) and determine whether novel biomarkers improve diagnostic accuracy. The investigators will conduct a prospective observational trial of 250 ED patients ≥65 years old with suspected pneumonia. The investigators will perform analyses overall and by subgroups, seeking common models to ease adoption.
Gender:
ALL
Ages:
65 years and above
Trial Updated:
01/15/2025
Locations: The Ohio State University, Columbus, Ohio
Conditions: Pneumonia
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Natural History, Management, and Genetics of the Hyperimmunoglobulin E Recurrent Infection Syndrome (HIES)
NCT00006150
Recruiting
The Hyper IgE Syndromes (HIES) are primary immunodeficiencies resulting in eczema and recurrent skin and lung infections. Autosomal dominant Hyper IgE syndrome (AD-HIIES; Job's syndrome) is caused by STAT3 mutations, and is a multi-system disorder with skeletal, vascular, and connective tissue manifestations. Understanding how STAT3 mutations cause these diverse clinical manifestations is critical to our complete understanding of bone metabolism, bronchiectasis, dental maturation, and atheroscle... Read More
Gender:
ALL
Ages:
Between 1 month and 120 years
Trial Updated:
02/20/2025
Locations: National Institutes of Health Clinical Center, Bethesda, Maryland
Conditions: Immune System Diseases, STAT3 Transcription Factor, Job Syndrome, Infections, Pneumonia
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Hyperpolarized 129-Xenon Imaging in Adult Hematopoietic Cell Transplant Recipients With Pulmonary Impairment
NCT05041140
Recruiting
This study is designed to measure the correlation of hyperpolarized 129-Xe magnetic resonance imaging (129-XeMRI) in allogeneic hematopoietic cell transplant (allo-HCT) recipients at MD Anderson Cancer Center (MDACC) who develop bronchiolitis obliterans syndrome (BOS) or BOS stage 0p (pulmonary impairment not meeting the definition for BOS, defined below) and controls with chronic graft-versus-host disease (cGVHD). The primary objective of the study is to correlate 129-Xenon measures of ventila... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
02/17/2025
Locations: M D Anderson Cancer Center, Houston, Texas
Conditions: Pulmonary, Pneumonia, Hematopoietic System--Cancer
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Follow-up Automatically vs. As-Needed Comparison (FAAN-C) Trial
NCT05471908
Recruiting
Compare the effectiveness of automatic vs as-needed (PRN) post-hospitalization follow-up for children who are hospitalized for common infections.
Gender:
ALL
Ages:
18 years and below
Trial Updated:
02/17/2025
Locations: Phoenix Children's Hospital, Phoenix, Arizona +13 locations
Conditions: Pneumonia, Urinary Tract Infections, Soft Tissue Infections, Gastroenteritis
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How OMT Benefits Newly Diagnosed Patients With Respiratory Illness When Given Alongside Other Standard Care.
NCT06495021
Recruiting
This study is to see Osteopathic Manipulative Therapy, or OMT, can aid in treating patients being seen for respiratory illness and associated symptoms. The hypothesis is that the addition of OMT therapy, alongside other standard care (such as a medication), can help lessen patient symptoms sooner than just other treatment alone, and the duration of the condition will shorten as well.
Gender:
ALL
Ages:
Between 65 years and 100 years
Trial Updated:
02/12/2025
Locations: Geisinger 65-Forward, Buckhorn, Bloomsburg, Pennsylvania
Conditions: Pneumonia, Sinusitis, Bronchitis, Respiratory Disease, Respiratory Tract Infections
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The Effects of Endotracheal Suctioning on Pain and Serum Markers
NCT06692400
Recruiting
The goal of this experimental study is to understand if endotracheal tube (ETT) suctioning increases pain and causes stress on the body in intubated adult ICU patients. These patients are already on ventilators, which means they need suctioning to keep their airways clear, but this procedure may be uncomfortable and cause stress. The main questions this study aims to answer are: Does ETT suctioning raise pain levels as measured by the Critical-Care Pain Observation Tool (CPOT)? Does ETT suctio... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
02/12/2025
Locations: Loma Linda University Medical Center Troesh Medical Campus, Loma Linda, California
Conditions: Intensive Care Unit ICU, Intubation, Critical Illness, Mechanical Ventilation, Pain Measurement, Pain, Procedural, Oxidative Stress, Hypoxia, Biomarkers / Blood, Adult, Uric Acid, Sepsis, COVID, Influenza, Pneumonia
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Study of Lung Proteins in Patients With Pneumonia
NCT00077909
Recruiting
This study will examine the different types of proteins present in the lungs of patients with pneumonia to explore the causes of different types of the disease. Pneumonia is a condition that causes lung inflammation AND is often caused by an infection. It is usually diagnosed by lung x-rays and listening to the chest with a stethoscope. This method can diagnose pneumonia, but it does not provide information on the cause of the inflammation - information that might be helpful in guiding treatment... Read More
Gender:
ALL
Ages:
Between 3 years and 99 years
Trial Updated:
01/24/2025
Locations: National Institutes of Health Clinical Center, Bethesda, Maryland
Conditions: Pneumonia, Pulmonary Disease, Lung Disease
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A Vaccine (CIMAvax-EGF) for the Prevention of Lung Cancer Development or Recurrence
NCT04298606
Recruiting
This early phase I trial studies the side effects of a vaccine called CIMAvax-EGF and to see how well it works in preventing lung cancer from developing in patients at high risk for lung cancer or coming back (recurrence) in stage IB-IIIA non-small cell lung cancer survivors. In many cancers such as lung cancer, there is a protein receptor called EGFR (epidermal growth factor receptor) that is overexpressed within these cancers. Activation of EGFR has shown to lead to tumor growth and developmen... Read More
Gender:
ALL
Ages:
Between 50 years and 79 years
Trial Updated:
01/16/2025
Locations: Roswell Park Cancer Institute, Buffalo, New York
Conditions: Chronic Obstructive Pulmonary Disease, Lung Non-Small Cell Carcinoma, Pneumonia, Stage IB Lung Cancer AJCC v8, Stage II Lung Cancer AJCC v8, Stage IIA Lung Cancer AJCC v8, Stage IIB Lung Cancer AJCC v8, Stage IIIA Lung Cancer AJCC v8
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Reducing Overuse of Antibiotics with Decision Support
NCT06788093
Recruiting
Eliminating inappropriate antibiotic use in pediatric lower respiratory tract infections (LRTI) is the central focus of this research. LRTIs (pneumonia, bronchiolitis, and infection-related exacerbations of asthma) account for nearly one-third of all emergency department (ED) visits and 40% of all infection-related hospitalizations in US children. LRTIs also account for more antibiotic use in children's hospitals than any other condition, despite most LRTIs being viral in nature. Inappropriate a... Read More
Gender:
ALL
Ages:
Between 6 months and 17 years
Trial Updated:
01/16/2025
Locations: Benioff Children's Hospital - Oakland, Oakland, California +2 locations
Conditions: Lower Respiratory Tract Infection, Pneumonia, Asthma, Bronchiolitis, Viral
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Individualizing Corticosteroid Use in Pneumonia
NCT05334316
Recruiting
In this study, researchers propose a unique (individualized) approach to steroid treatment seeking to give the right dose of steroid to the right patient and at the right time. This study seeks to compare usual care to an individualized steroid dosing strategy by testing a marker of inflammation in the blood called C- reactive protein (CRP). The overall goal is to reduce an individual's exposure to steroids and the risk of potential side effects thereby increasing the potential benefit of using... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
12/06/2024
Locations: Mayo Clinic Rochester, Rochester, Minnesota
Conditions: Pneumonia
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A Study to Learn About How 20-Valent Pneumococcal Conjugate Vaccine Works in a Real-world Setting
NCT05452941
Recruiting
The purpose of this study is to learn about how well the 20-valent pneumococcal conjugate vaccine (20vPnC) works against radiologically-confirmed community-acquired pneumonia (RAD+CAP) due to the 7 new serotypes (types of a bacteria called Streptococcus pneumoniae that cause pneumonia) included in 20vPnC vaccine. This study is seeking participants who: * are male or female ≥65 years of age. * are hospitalized with physician suspicion of community acquired pneumonia (CAP). * have pneumonia conf... Read More
Gender:
ALL
Ages:
65 years and above
Trial Updated:
12/01/2024
Locations: Kaiser Permanete Baldwin Park, Baldwin Park, California +94 locations
Conditions: Pneumonia
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Quasi-Randomized Evaluation of the UCLA Next Day Clinic (NDC)
NCT06526884
Recruiting
The Next Day Clinic (NDC) is a quality improvement initiative that will be launched and operated by UCLA Health starting July 22, 2024. Its goals are to improve patient care and safety and to maximize cost effectiveness. The way it does this is by identifying patients in the ED who would normally be admitted for low-acuity conditions, and diverting them to a high-acuity clinic the following day called the NDC. This will help decompress the ED and the hospital, and allow for overall higher qualit... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
10/25/2024
Locations: Ronald Reagan UCLA Medical Center, Los Angeles, California
Conditions: Pneumonia, Syncope, Congestive Heart Failure, Cellulitis, Pyelonephritis, AKI - Acute Kidney Injury, Diabetic Foot Infection, Osteomyelitis
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