There are currently 29 active clinical trials seeking participants for Premature Birth research studies. The states with the highest number of trials for Autism participants are New York, California, Illinois and Ohio.
Outpatient Antibiotics Following Previable Rupture of Membranes (pPPROM) Between 18 0/7 and 22 6/7 Weeks Gestational Age
Recruiting
A randomized, controlled, non-placebo trial to primarily assess the effect of oral, outpatient antibiotics (i.e., azithromycin and amoxicillin) on latency (i.e., proportion of patients that deliver within 28 days from membrane rupture) following previable, prelabor rupture of membranes between 18 0/7 and 22 6/7 weeks gestational age.
Gender:
Female
Ages:
18 years and above
Trial Updated:
03/14/2024
Locations: University Hospitals, Cleveland, Ohio +2 locations
Conditions: Pregnancy Preterm, Pregnancy Prom, PROM, Preterm (Pregnancy), PROM (Pregnancy), Premat Rupture Membranes Preterm Unspec to Length of Time Between Rupture/Labor, Premature Birth
Optimizing Family Counseling for Anticipated Extremely Preterm Delivery
Recruiting
Antenatal family counseling for anticipated extremely preterm deliveries remains ethically and practically challenging for maternal-fetal medicine specialists and neonatologists alike. The overall goal of this project is to improve antenatal counseling and counseling outcomes for families facing anticipated extremely preterm delivery through innovative, interdisciplinary simulation-based education for maternal fetal medicine specialists and neonatologists, using language preferred by families, a... Read More
Gender:
All
Ages:
Between 18 years and 99 years
Trial Updated:
03/13/2024
Locations: Boston Children's Hosptial, Boston, Massachusetts +2 locations
Conditions: Preterm Pregnancy, Premature Birth
Nasogastric/Orogastric Tube Placement Confirmation in Neonates Utilizing Self-contained pH Device, a Feasibility Study
Recruiting
This study is looking at using a self-contained pH device that will assist in confirming placement of a nasogastric or orogastric tube placed in the stomach of hospitalized infants.
Gender:
All
Ages:
2 years and below
Trial Updated:
02/29/2024
Locations: University of Minnesota, Minneapolis, Minnesota
Conditions: Premature Birth
US and Neurodevelopmental Outcomes in the Neonatal Intensive Care Unit (NICU)
Recruiting
The objective of the project is to identify clinical factors (nutritional and non-nutritional) which are associated with ultrasound measurements of muscle and adipose tissue and to determine whether these ultrasound measurements are predictive of later metabolic and neurodevelopmental outcomes in premature infants, a population at risk for developmental delay, obesity, and metabolic disease. The investigators expect that a better understanding of these relationships will lead to the incorporatio... Read More
Gender:
All
Ages:
Between 25 weeks and 34 weeks
Trial Updated:
02/28/2024
Locations: University of Minnesota, Minneapolis, Minnesota
Conditions: Premature Birth
Effects of a Physical Therapy Intervention on Motor Delay in Infants Admitted to a Neonatal Intensive Care Unit
Recruiting
Study Aims Pilot study: Due to the large recruitment goal and length of the project, the study team/PIs will evaluate the first cohort of 6-10 participants to refine study procedures and study-related materials. If no major modifications are made to the protocol as a result of this evaluation, data from these participants will be included for analysis. Aim 1: Evaluate the efficacy of an early, evidence-based, clinical experience-based therapeutic intervention (from the NICU to 12-months correc... Read More
Gender:
All
Ages:
Between 33 weeks and 48 weeks
Trial Updated:
02/21/2024
Locations: Ann & Robert H. Lurie Children's Hospital of Chicago, Chicago, Illinois +2 locations
Conditions: Motor Delay, Premature Birth, Intraventricular Hemorrhage, Hypoxic-Ischemic Encephalopathy, Bronchopulmonary Dysplasia
Prophylactic Minimally Invasive Surfactant Evaluation
Recruiting
The purpose of this study is to explore the question: Does prophylactic administration of exogenous surfactant in the delivery room, using a minimally-invasive technique, improve outcome in preterm infants 22-29 weeks' gestation compared to rescue treatment using the same technique?
Gender:
All
Ages:
15 minutes and below
Trial Updated:
02/19/2024
Locations: Northshore University Healthsystem, Evanston, Illinois
Conditions: Respiratory Distress Syndrome, Newborn, Premature Birth
Parent Training for Parents of Toddlers Born Very Premature:
Recruiting
The purpose of the study is to test the effects of the ezParent (web-based parent training program) intervention and telephone coaching calls (coach) on parent and child outcomes after 3-, 6-, and 12-months. Parents (n=220) will be randomized using a 2 x 2 factorial design to: (1) ezParent+coach, (2) ezParent, (3) Active Control+coach, or (4) Active control. The investigators will address these aims: Determine the independent and combined effects of ezParent and coaching calls on parent outcome... Read More
Gender:
All
Ages:
20 months and above
Trial Updated:
02/19/2024
Locations: Rush University Children's Hospital, Chicago, Illinois +2 locations
Conditions: Parenting, Premature Birth, Parenting Intervention, Problem Behavior
The Periviable GOALS Decision Support Tool
Recruiting
The Periviable GOALS (Getting Optimal Alignment around Life Support) decision support tool (DST) is meant to facilitate informed shared decision-making regarding neonatal resuscitation for families facing the threat of a periviable delivery (deliveries occurring between 22 0/7 - 25 6/7 weeks gestational age). It is designed for parents to review independent of their clinician, and is intended to supplement, not replace, clinician counseling. The focus of the DST is the provision of patient-cente... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
01/08/2024
Locations: The University of California San Diego, San Diego, California +3 locations
Conditions: Pregnancy Preterm, Premature Birth, Pregnancy Complications, Obstetric Labor, Premature, Obstetric Labor Complications
LATe Cerclage in High-risk Pregnancies (LATCH)
Recruiting
The goal of this clinical trial is to determine whether cervical cerclage reduces the risk of preterm birth in patients with a short transvaginal ultrasound (TVU) cervical length (CL) ≤25mm between 24 0/7-26 6/7 weeks.
Gender:
Female
Ages:
Between 18 years and 50 years
Trial Updated:
11/28/2023
Locations: Thomas Jefferson University, Philadelphia, Pennsylvania
Conditions: Premature Birth
Spinal Stimulation and Mobility Devices
Recruiting
This research study will combine non-invasive spinal stimulation with mobility devices to examine the acute impact of the individual and combined effects of these innovative techniques on mobility in children with cerebral palsy.
Gender:
All
Ages:
Between 4 years and 70 years
Trial Updated:
10/23/2023
Locations: University of Washington, Seattle, Washington
Conditions: Cerebral Palsy, Stroke, Premature Birth, Hypoxic-Ischemic Encephalopathy, Periventricular Leukomalacia
Post-Vent, the Sequelae: Personalized Prognostic Modeling for Consequences of Neonatal Intermittent Hypoxemia in Preterm Infants at Pre-School Age
Recruiting
Despite improved survival of extremely premature infants in recent decades, neonatal intensive care unit (NICU) graduates are diagnosed with asthma, sleep disordered breathing (SDB) in childhood, and neurodevelopmental impairments (NDI) at significant rates, disproportionate to their term peers. Early detection and intervention are critical to mitigate the impact of these impairments. Mechanisms leading from premature birth to these undesirable outcomes remain unclear, and accurate prognostic me... Read More
Gender:
All
Ages:
Between 30 weeks and 66 months
Trial Updated:
08/30/2023
Locations: Ann & Robert H. Lurie Children's Hospital of Chicago, Chicago, Illinois
Conditions: Premature Birth, Asthma in Children, Sleep-Disordered Breathing, Neurodevelopmental Disorders
Nourishing Beginnings: Addressing Food Insecurity During Pregnancy
Recruiting
This is a pilot project designed to test the feasibility of implementing a community health worker (CHW)-led intervention to improve nutritious food access and consumption among pregnant people and to evaluate the effectiveness of this approach. The project will be conducted in partnership with the Greater Cleveland Food Bank and the Better Health Partnership Community Health Worker HUB
Gender:
Female
Ages:
18 years and above
Trial Updated:
08/28/2023
Locations: Better Health Partnership CHW HUB, Cleveland, Ohio
Conditions: Pregnancy Related, Food Insecurity, Premature Birth, Pregnancy Complications