There are currently 11 active clinical trials seeking participants for Sarcopenia research studies. The states with the highest number of trials for Sarcopenia participants are Florida, Texas, Minnesota and Illinois.
Sarcopenia Magnetic Resonance Imaging Evaluation (SUSIE)
NCT04869813
Recruiting
The goal of the proposed research is to investigate Magnetic Resonance (MR) Fingerprinting and P-MRS (Phosphorus-31 MR Spectroscopy) imaging for characterization of skeletal muscle in heart failure patients with sarcopenia. Heart failure patients with and without sarcopenia will be scanned using MR Fingerprinting and an existing Post-exercise phosphocreatine (PCr) recovery MR imaging protocol to obtain characteristic profiles of quantitative T1, T2, and PCr recovery rate.
Gender:
ALL
Ages:
40 years and above
Trial Updated:
01/06/2025
Locations: Cleveland Clinic, Cleveland, Ohio
Conditions: Sarcopenia
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C-Protein in Fatigue and Aging
NCT05926219
Recruiting
This study is investigating changes to the proteins in skeletal muscle that contribute to reduced muscle size and muscle function that occurs with aging.
Gender:
ALL
Ages:
Between 18 years and 80 years
Trial Updated:
01/06/2025
Locations: University of Oregon, Eugene, Oregon
Conditions: Aging, Muscle Atrophy or Weakness, Sarcopenia in Elderly, Sarcopenia
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Myopenia and Mechanisms of Chemotherapy Toxicity in Older Adults With Colorectal Cancer
NCT03998202
Recruiting
This study will examine the association between low muscle mass (myopenia) at diagnosis and chemotherapy toxicity in older adults with newly diagnosed advanced colorectal cancer.
Gender:
ALL
Ages:
60 years and above
Trial Updated:
01/03/2025
Locations: Beebe South Coastal Health Campus, Frankford, Delaware +135 locations
Conditions: Colorectal Cancer, Sarcopenia
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Exercise and Nutritional Prehabilitation for Head and Neck Cancer Patients
NCT06722508
Recruiting
This study examines the acceptability, feasibility, and safety in developing a prehabilitation program for head and neck cancer patients. The purpose of this research is to access the safety and acceptability of using a prehabilitation program before head and neck cancer surgery.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
12/05/2024
Locations: UC Davis Health, Sacramento, California +1 locations
Conditions: Head Cancer, Neck Cancer, Sarcopenia, Head and Neck Cancer
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Identifying Modifiable PAtient Centered Therapeutics (IMPACT) Frailty
NCT04717869
Recruiting
Frailty, the decline in physical and cognitive reserves leading to vulnerability to stressors is increasingly being recognized as a public health concern. Although multiple measures exist that can identify frail patients, very little is known about how or when to intervene. Sarcopenia, or the degree of muscle wasting, is closely correlated to frailty and patient outcomes. This is a prospective cohort study of critically ill patients to identify modifiable risk factors of sarcopenia, as potential... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
11/20/2024
Locations: Ronald Reagan UCLA Medical Center, Department of Anesthesiology & Perioperative Medicine, Los Angeles, California
Conditions: Frailty, Sarcopenia
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Impacts of Nicotinamide Riboside on Functional Capacity and Muscle Physiology in Older Veterans
NCT04691986
Recruiting
Frailty is an age-associated clinical condition of poor physiological reserve that increases risks for falls, hospitalization and mortality. Nicotinamide adenine dinucleotide (NAD) is a critical co-factor needed for many cellular processes. The natural levels of NAD decline aging and this has been linked to physical performance decline in animals. Human trials have demonstrated that nicotinamide riboside (NR), a form of vitamin B3, is safe and effectively increases NAD+ levels. In animal studies... Read More
Gender:
ALL
Ages:
Between 65 years and 85 years
Trial Updated:
11/06/2024
Locations: Kansas City VA Medical Center, Kansas City, MO, Kansas City, Missouri
Conditions: Sarcopenia, Nicotinamide Adenine Dinucleotide Concentration, Muscle Quality and NAD+ Content
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Adverse Outcomes and Mortality in Liver Transplant
NCT05477277
Recruiting
Prospective natural history pilot study to explore the link between muscle composition using an MRI-based Muscle Assessment Score (MAsS) and adverse outcomes in liver transplant candidates.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
09/30/2024
Locations: Mayo Clinic Arizona, Phoenix, Arizona
Conditions: End Stage Liver DIsease, Sarcopenia, Sarcopenic Obesity, Cirrhosis
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Impact of Diet on the Gut-Muscle Axis in Older Adults
NCT05549622
Recruiting
Muscle health declines during aging. One factor that may impact muscle health is the community of bacteria that live in our intestines, but studies aimed at improving muscle health by targeting the gut in older adults are sparse. The primary goal of this study is to use a diet that is enriched in soluble fiber, which is exclusively utilized by gut bacteria to make substances that can impact muscle health, to improve muscle-related measures in older adults.
Gender:
ALL
Ages:
65 years and above
Trial Updated:
08/20/2024
Locations: Jean Mayer Human Nutrition Research Center on Aging at Tufts University, Boston, Massachusetts
Conditions: Sarcopenia, Dietary Exposure, Microbial Colonization
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Ankle Assistance and Resistance in Older Adults
NCT06284525
Recruiting
The goal of this research protocol is to improve mobility in older individuals through advances in wearable assistive devices by focusing on two specific aims. The first aim is to study if targeted ankle resistance gait training improves walking performance in older individuals. The second aim is to evaluate the potential of wearable assistance at the ankle, knee, and/or hip joints to increase walking performance in older individuals.
Gender:
All
Ages:
Between 65 years and 85 years
Trial Updated:
02/21/2024
Locations: Northern Arizona University, Flagstaff, Arizona
Conditions: Sarcopenia
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Body Composition Changes After TIPS and Associated Clinical Outcomes
NCT05420753
Recruiting
The purpose of this study is to prospectively assess the impact of TIPS creation on muscle mass and physical function in patients with cirrhosis, and to determine whether these changes correlate with improved outcomes in patients awaiting liver transplantation. Retrospective observational studies have shown improvement in muscle mass and body composition in cirrhotic patients undergoing TIPS. The investigators aim to now prospectively study this through a pilot randomized controlled trial tracki... Read More
Gender:
All
Ages:
Between 18 years and 99 years
Trial Updated:
11/02/2023
Locations: Oregon Health and Science University, Portland, Oregon
Conditions: Cirrhosis, Liver, Sarcopenia
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Effects of Graded Protein Intake on Body Composition in Older Adults
NCT04845282
Recruiting
This clinical trial is intended to evaluate the effects of protein intake graded to resistance training volume over a 10-week period on macroscopic skeletal muscle adaptations and body composition. Briefly, all participants will complete a progressive resistance training protocol for 10 weeks, with one group consuming a constant amount of total daily protein (RDA of 0.8g/kg/day) to serve as an active comparator. The alternative group will consume total daily protein and protein supplement in a g... Read More
Gender:
All
Ages:
Between 55 years and 110 years
Trial Updated:
04/26/2022
Locations: Wake Forest University Clinical Research Center, Winston-Salem, North Carolina
Conditions: Sarcopenia
Register for Updates