There are currently 15 active clinical trials seeking participants for Sarcopenia research studies. The states with the highest number of trials for Sarcopenia participants are Florida, Texas, Minnesota and California.
The Foods & Oil to Repair, Correct and Enhance Strength (FORCES) Study
NCT06361511
Recruiting
The proposed research is a parallel arm, randomized placebo-controlled clinical trial designed to assess changes in muscle strength, volume, fatigue resistance, and mobility in older adults after daily consumption of 12g of linoleic acid-rich oil.
Gender:
ALL
Ages:
Between 65 years and 80 years
Trial Updated:
05/23/2025
Locations: The Ohio State University, Columbus, Ohio
Conditions: Sarcopenia
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Sarcopenia Magnetic Resonance Imaging Evaluation (SUSIE)
NCT04869813
Recruiting
The goal of the proposed research is to investigate Magnetic Resonance (MR) Fingerprinting and P-MRS (Phosphorus-31 MR Spectroscopy) imaging for characterization of skeletal muscle in heart failure patients with sarcopenia. Heart failure patients with and without sarcopenia will be scanned using MR Fingerprinting and an existing Post-exercise phosphocreatine (PCr) recovery MR imaging protocol to obtain characteristic profiles of quantitative T1, T2, and PCr recovery rate.
Gender:
ALL
Ages:
40 years and above
Trial Updated:
06/19/2025
Locations: Cleveland Clinic, Cleveland, Ohio
Conditions: Sarcopenia
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Project Gnosis: the Neurophysical and Psychosocial Health Outcomes of Tai Chi for Older Adults with Cognitive Concerns or Mild Cognitive Impairment
NCT06828926
Recruiting
Mild Cognitive Impairment (MCI) in older adults is linked to muscle loss (sarcopenia) and can lead to dementia, with pain further impacting cognitive and physical performance. Tai Chi, a mind-body exercise, is recommended for managing MCI as it supports cognitive function, mood, and physical health. The investigators' first goal is to characterize the correlation of heart rate variability and cortical activity on cognitive function and the psychosocial correlates of pain interference and social... Read More
Gender:
ALL
Ages:
60 years and above
Trial Updated:
02/12/2025
Locations: Ohio University, Athens, Ohio
Conditions: Mild Cognitive Impairment (MCI), Sarcopenia
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Adverse Outcomes and Mortality in Liver Transplant
NCT05477277
Recruiting
Prospective natural history pilot study to explore the link between muscle composition using an MRI-based Muscle Assessment Score (MAsS) and adverse outcomes in liver transplant candidates.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
08/12/2025
Locations: Mayo Clinic Arizona, Phoenix, Arizona
Conditions: End Stage Liver DIsease, Sarcopenia, Sarcopenic Obesity, Cirrhosis
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Frailty and Muscle Strength Tests in Older Adults Undergoing Major Surgery
NCT06988176
Recruiting
The goal of this observational study is to learn if simple tests for frailty and muscle strength can help predict which older adults (age 65 and older) are at higher risk for problems after major abdominal surgery. The main questions it aims to answer are: * Do measures of frailty and muscle strength, taken before surgery, predict complications after surgery? * Can these tests be easily done during a routine pre-surgical visit? Participants will: * Complete brief tests measuring muscle stren... Read More
Gender:
ALL
Ages:
65 years and above
Trial Updated:
08/07/2025
Locations: University of North Carolina, Chapel Hill, North Carolina
Conditions: Frailty, Sarcopenia, Sarcopenia in Elderly, Post Operative Complications, Nutrition Assessment, Risk Assessment, Elderly (People Aged 65 or More), Hand Strength, Muscle Strength
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Multidimensional Predictive Modeling to Understand Mechanisms of Exercise Response Heterogeneity in Older Adults (M3AX)
NCT06507189
Recruiting
Aging-related functional declines are thought to be caused by hallmark biological processes that ultimately manifest in physical, mental, and metabolic impairments that compromise healthspan and quality of life. Exercise is a multipotent treatment with promise to mitigate most aging hallmarks, but there is substantial variability in exercisƒe responsiveness. Combining endurance and resistance training in alignment with public health guidelines will be used to better understand variable exercise... Read More
Gender:
ALL
Ages:
60 years and above
Trial Updated:
07/30/2025
Locations: Florida Institute for Human and Machine Cognition, Pensacola, Florida +1 locations
Conditions: Sarcopenia
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Myopenia and Mechanisms of Chemotherapy Toxicity in Older Adults With Colorectal Cancer
NCT03998202
Recruiting
This study will examine the association between low muscle mass (myopenia) at diagnosis and chemotherapy toxicity in older adults with newly diagnosed advanced colorectal cancer.
Gender:
ALL
Ages:
60 years and above
Trial Updated:
07/14/2025
Locations: Beebe South Coastal Health Campus, Millville, Delaware +142 locations
Conditions: Colorectal Cancer, Sarcopenia
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Strength Training and Resveratrol
NCT06585865
Recruiting
The main goal of this study is to find out if supplementing with resveratrol improves skeletal muscle adaptations to strengthening exercise (resistance training or strength training) in adults age 60+, and to determine whether circulating vehicles of inter-organ communication (extracellular vesicles) and their cargo might help explain those responses. The investigators will also examine whether resveratrol supplementation improves blood vessel function and cognitive function (brain health) in re... Read More
Gender:
ALL
Ages:
60 years and above
Trial Updated:
06/27/2025
Locations: Department of Kinesiology & Sport Management, Texas Tech University, Lubbock, Texas
Conditions: Sarcopenia, Anabolic Resistance
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C-Protein in Fatigue and Aging
NCT05926219
Recruiting
This study is investigating changes to the proteins in skeletal muscle that contribute to reduced muscle size and muscle function that occurs with aging.
Gender:
ALL
Ages:
Between 18 years and 80 years
Trial Updated:
05/06/2025
Locations: University of Oregon, Eugene, Oregon
Conditions: Aging, Muscle Atrophy or Weakness, Sarcopenia in Elderly, Sarcopenia
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Effects of Whole-body Electrical Muscle Stimulation Exercise on Spinal Motoneuronal Activation in Older Adults
NCT06689618
Recruiting
During this pilot study, the investigators will examine the effects of whole-body electrical muscle stimulation exercise (WB-EMS Exercise) on motoneuronal activation in healthy adults, which typically decreases with age. The investigators will also test whether WB-EMS Exercise will improve measures of physical function. Participants will undergo clinical and electrophysiologic testing before and after the WB-EMS Exercise intervention. The WB-EMS Exercise intervention will be delivered two times... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
04/09/2025
Locations: NextGen Precision Health Building, Clinical and Translational Science Unit, Columbia, Missouri
Conditions: Aging, Sarcopenia, Sarcopenia in Elderly
Register for Updates
Exercise and Nutritional Prehabilitation for Head and Neck Cancer Patients
NCT06722508
Recruiting
This study examines the acceptability, feasibility, and safety in developing a prehabilitation program for head and neck cancer patients. The purpose of this research is to access the safety and acceptability of using a prehabilitation program before head and neck cancer surgery.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
12/05/2024
Locations: UC Davis Health, Sacramento, California +1 locations
Conditions: Head Cancer, Neck Cancer, Sarcopenia, Head and Neck Cancer
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Identifying Modifiable PAtient Centered Therapeutics (IMPACT) Frailty
NCT04717869
Recruiting
Frailty, the decline in physical and cognitive reserves leading to vulnerability to stressors is increasingly being recognized as a public health concern. Although multiple measures exist that can identify frail patients, very little is known about how or when to intervene. Sarcopenia, or the degree of muscle wasting, is closely correlated to frailty and patient outcomes. This is a prospective cohort study of critically ill patients to identify modifiable risk factors of sarcopenia, as potential... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
11/20/2024
Locations: Ronald Reagan UCLA Medical Center, Department of Anesthesiology & Perioperative Medicine, Los Angeles, California
Conditions: Frailty, Sarcopenia
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