There are currently 22 active clinical trials seeking participants for Seizures research studies. The states with the highest number of trials for Seizures participants are Florida, California, Texas and New York.
Ear-Seizure Detection (EarSD) Study
NCT06598189
Recruiting
The proposed study is an investigator-initiated study that aims to measure the accuracy of a wearable seizure detection and prediction device (Ear-Seizure Detection Device (EarSD)) by simultaneous recording with conventional video-EEG (Electroencephalogram) on patients with epileptic seizures in the Epilepsy Monitoring Unit of the hospital.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
03/21/2025
Locations: Ummmc-Memorial Campus, Worcester, Massachusetts +1 locations
Conditions: Seizures, Epilepsy
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Investigate Efficacy and Safety of Carisbamate As Adjunctive Treatment for Seizures Associated with LGS in Children and Adults
NCT05219617
Recruiting
The primary objective is to evaluate the efficacy of carisbamate (YKP509) as adjunctive treatment in reducing the number of drop seizures (tonic, atonic, and tonic-clonic) compared with placebo in pediatric and adult subjects (age 4-55 years) diagnosed with Lennox Gastaut Syndrome (LGS).
Gender:
ALL
Ages:
Between 4 years and 55 years
Trial Updated:
03/20/2025
Locations: Stanford University Hospital, Palo Alto, California +70 locations
Conditions: Seizures, Lennox Gastaut Syndrome
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Oxygen Toxicity: Mechanisms in Humans
NCT05761756
Recruiting
The goal of this clinical trial is to learn about the mechanisms of oxygen toxicity in scuba divers. The main questions it aims to answer are: * How does the training of respiratory muscles affect oxygen toxicity? * How do environmental factors, such as sleep deprivation, the ingestion of commonly utilized medications, and chronic exposure to carbon dioxide, impact the risk of oxygen toxicity? * How does immersion in water affect the development of oxygen toxicity? Participants will be asked t... Read More
Gender:
ALL
Ages:
Between 18 years and 45 years
Trial Updated:
03/13/2025
Locations: Duke University Health Sustem, Durham, North Carolina
Conditions: Oxygen Toxicity, Hypercapnia, Seizures
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Investigating Epilepsy: Screening and Evaluation
NCT03478852
Recruiting
Background: Epilepsy affects about 1 percent of the U.S. population. Most people with epilepsy respond well to medicine, but some do not. Researchers want people who have diagnosed or suspected epilepsy to participate in ongoing studies. They want to learn more about clinical care for epilepsy. They want fellows and residents to learn more about the care of people with epilepsy. Objectives: To learn more about seizures and find ways to best treat people with drug-resistant epilepsy. Eligibil... Read More
Gender:
ALL
Ages:
Between 8 years and 110 years
Trial Updated:
02/21/2025
Locations: National Institutes of Health Clinical Center, Bethesda, Maryland
Conditions: Seizures, Epilepsy, Epilepsy, Temporal Lobe, Partial Epilepsy
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Transnasal Induction of Normothermia for Neurogenic Fever
NCT06038513
Recruiting
The objective of this study is to evaluate the efficacy of the COOLSTAT® Transnasal Thermal Regulating Device in reducing temperature in a population of febrile subjects who meet the inclusion/exclusion criteria.
Gender:
ALL
Ages:
Between 18 years and 85 years
Trial Updated:
02/12/2025
Locations: University of Maryland Medical Center, Baltimore, Maryland
Conditions: Stroke, Ischemic, Stroke Hemorrhagic, Seizures, Metabolic Encephalopathy
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Electrographic Seizure Management and Neurobehavioral Outcomes in Critically Ill Children
NCT03419260
Recruiting
Electrographic seizures are common in critically ill patients leading to increased use of resource-intense continuous EEG monitoring for seizure identification and management. When identified, electrographic seizures are generally treated with anti-seizure medications, but there are very limited data available regarding optimal treatment in terms of the efficacy or safety of specific anti-seizure medications or overall management strategies. This is a single-center prospective observational stu... Read More
Gender:
ALL
Ages:
Between 1 month and 18 years
Trial Updated:
02/03/2025
Locations: Children's Hospital of Philadelphia, Philadelphia, Pennsylvania
Conditions: Seizures
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Modulating Movement Intention Via Cortical Stimulation
NCT03233399
Recruiting
The purpose of this protocol is to learn about movement intention and volition. To improve such knowledge, investigators will conduct sub-studies using multiple non-invasive methodologies. These results could provide preliminary data for subsequent studies evaluating local and global efficacy of plasticity-inducing treatments for PMD symptoms.
Gender:
ALL
Ages:
Between 18 years and 65 years
Trial Updated:
01/28/2025
Locations: New York University School of Medicine, New York, New York
Conditions: Seizures, Seizure Disorder, Psychogenic Movement Disorder
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Pivotal-Safety and Therapeutic Measures of tDCS in Patients With Refractory Focal Epilepsy
NCT04770337
Recruiting
This is a multiple site, randomized, double blinded parallel-group controlled study. The purpose of this study is to evaluate efficacy, safety, and tolerability of repeated, daily sessions with the STARSTIM device, which delivers transcranial cathodal direct current stimulation (tDCS). Subjects will be treated with STARTSTIM or sham device for 10 sessions over a 2-week period. The subjects will be followed for an additional 10 weeks post treatment. Quality of Life questionnaires and adverse even... Read More
Gender:
ALL
Ages:
9 years and above
Trial Updated:
11/14/2024
Locations: Barrow Neurological Institute, St. Joseph's Hospital & Medical Center, Phoenix, Arizona +31 locations
Conditions: Refractory Epilepsy, Focal Seizure, Seizures, Focal, Seizures, Epilepsy in Children, Epilepsy, Epilepsy, Tonic-Clonic
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Longitudinal Study of Neurogenetic Disorders
NCT03492060
Recruiting
The purpose of this study is to analyze patterns in individuals with hnRNP (and other) genetic variants, including their neurological comorbidities, other medical problems and any treatment. The investigators will maintain an ongoing database of medical data that is otherwise being collected for routine medical care. The investigators will also collect data prospectively in the form of questionnaires, neuropsychological assessments, motor assessments, and electroencephalography to examine the la... Read More
Gender:
ALL
Ages:
All
Trial Updated:
10/24/2024
Locations: Columbia University Irving Medical Center, New York, New York
Conditions: Neurodevelopmental Disorders, Intellectual Disability, Developmental Delay, Autism Spectrum Disorder, Seizures, Hypertonia, Muscle, Hypotonia
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Acute Effects of Focused Ultrasound Modulation on EEG Behavior in Status Epilepticus Patients
NCT05784805
Recruiting
In this study, the investigators propose Pulsed Low-Intensity Focused Ultrasound (PLIFU) stimulation of brain regions that modulate (thalamus) or generate focal motor seizures (primary motor cortex), with the goal of ameliorating seizure activity in subjects in non-convulsive or focal motor status epilepticus. The course of treatment will consist of an initial 10 minute PLIFU treatment session with an option for a 2nd session if necessary. The primary objective of this study is to determine whe... Read More
Gender:
ALL
Ages:
Between 19 years and 85 years
Trial Updated:
10/01/2024
Locations: Yale New Haven Hospital, New Haven, Connecticut
Conditions: Seizures
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Pharmacological Modulation of Brain Oscillations in Memory Processing
NCT05594017
Recruiting
The goal of this study is to learn about the effects of scopolamine (an anticholinergic drug) on areas of the brain involved in memory, and changes it may have on brain activity. The investigators will do this by testing epileptic patients who are already undergoing intracranial surgery for seizure monitoring, and measuring the activity from the brain areas being assessed. The main questions it aims to answer are 1) whether scopolamine changes memory activity solely at encoding (the time when t... Read More
Gender:
ALL
Ages:
Between 18 years and 55 years
Trial Updated:
09/18/2024
Locations: University of Texas Southwestern Medical Center, Dallas, Texas
Conditions: Epilepsy, Seizures, Cognitive Impairment, Mild, Memory Disorders, Memory Loss
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Impact of Capturing Ictal Events With Ultra-long-term Ambulatory EEG Monitoring With Remote EEG Monitoring System.
NCT06027749
Recruiting
The goal of this clinical trial is to test Epitel's™ Remote EEG Monitoring System's (REMI™) ability to record electroencephalography (EEG) of seizure events in an ambulatory setting for extended periods (14 - 28 days) in patients presenting with questionable seizure characterization. The main questions it aims to answer are: • Can more seizure events be recorded in fourteen (14) days than can be recorded in three (3) days? • Do treating clinicians find clinical value in extended fourteen (14) -... Read More
Gender:
ALL
Ages:
Between 18 years and 70 years
Trial Updated:
08/26/2024
Locations: University of South Florida, Tampa, Florida +1 locations
Conditions: Epilepsy, Seizures
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