There are currently 22 active clinical trials seeking participants for Seizures research studies. The states with the highest number of trials for Autism participants are Florida, California, Texas and New York.
Detecting Absence Seizures Using Hyperventilation and Eye Movement Recordings
NCT06093490
Recruiting
This study is being done to find out if a smartphone app can identify absence seizures. Children who have a history of absence seizures, as well as children without any seizure history, will be testing out the app. If participating the child will be guided through hyperventilation, an activity that asks the child to take quick, deep breaths. The app will record video of the child's face and sounds they make during hyperventilation. Hyperventilation is a safe and established technique frequently... Read More
Gender:
All
Ages:
Between 4 years and 12 years
Trial Updated:
02/15/2024
Locations: Cincinnati Children's Hospital, Cincinnati, Ohio
Conditions: Absence Epilepsy, Childhood, Absence Seizures, Absence Epilepsy, Epilepsy in Children, Staring, Seizures
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Database Of Clinical Data For Individuals With Variants In The IRF2BPL Gene
NCT03892798
Recruiting
This protocol serves as a data collection tool for individuals with variants (missense, nonsense, frameshifts) in the IRF2BPL gene (MIM 611720), which causes Neurodevelopmental Regression, Seizures, Autism and Developmental Delay (NEDAMSS, MIM 618088) and may be involved in other neurodevelopmental presentations. This information will be analyzed to develop a better understanding of the findings and progression of symptoms in individuals with variants in the IRF2BPL gene.
Gender:
All
Ages:
Between 2 months and 80 years
Trial Updated:
07/05/2023
Locations: Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio
Conditions: Autism Spectrum Disorder, Movement Disorders, Seizures, Dystonia, NEDAMSS
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Pediatric Dose Optimization for Seizures in Emergency Medical Services
NCT05121324
Recruiting
The Pediatric Dose Optimization for Seizures in Emergency Medical Services (PediDOSE) study is designed to improve how paramedics treat seizures in children on ambulances. Seizures are one of the most common reasons why people call an ambulance for a child, and paramedics typically administer midazolam to stop the seizure. One-third of children with active seizures on ambulances arrive at emergency departments still seizing. Prior research suggests that seizures on ambulances continue due to und... Read More
Gender:
All
Ages:
Between 6 months and 13 years
Trial Updated:
04/15/2024
Locations: University of Arizona, Tucson, Arizona +19 locations
Conditions: Seizures
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Investigating Epilepsy: Screening and Evaluation
NCT03478852
Recruiting
Background: Epilepsy affects about 1 percent of the U.S. population. Most people with epilepsy respond well to medicine, but some do not. Researchers want people who have diagnosed or suspected epilepsy to participate in ongoing studies. They want to learn more about clinical care for epilepsy. They want fellows and residents to learn more about the care of people with epilepsy. Objectives: To learn more about seizures and find ways to best treat people with drug-resistant epilepsy. Eligibil... Read More
Gender:
All
Ages:
8 years and above
Trial Updated:
04/03/2024
Locations: National Institutes of Health Clinical Center, Bethesda, Maryland
Conditions: Seizures, Epilepsy, Epilepsy, Temporal Lobe, Partial Epilepsy
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Modulating Movement Intention Via Cortical Stimulation
NCT03233399
Recruiting
The purpose of this protocol is to learn about movement intention and volition. To improve such knowledge, investigators will conduct sub-studies using multiple non-invasive methodologies. These results could provide preliminary data for subsequent studies evaluating local and global efficacy of plasticity-inducing treatments for PMD symptoms.
Gender:
All
Ages:
Between 18 years and 65 years
Trial Updated:
03/25/2024
Locations: New York University School of Medicine, New York, New York
Conditions: Seizures, Seizure Disorder, Psychogenic Movement Disorder
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A Trial of the Efficacy and Safety of CVL-865 as Adjunctive Therapy in the Treatment of Focal Onset Seizures
NCT04244175
Recruiting
The purpose of this study is to assess the efficacy, safety, and tolerability profile of CVL-865 as adjunctive treatment in participants with drug-resistant focal onset seizures.
Gender:
All
Ages:
Between 18 years and 75 years
Trial Updated:
03/06/2024
Locations: Little Rock, Arkansas, Little Rock, Arkansas +88 locations
Conditions: Seizures
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RNS System LGS Feasibility Study
NCT05339126
Recruiting
To generate preliminary safety and effectiveness data for brain-responsive neurostimulation of thalamocortical networks as an adjunctive therapy in reducing the frequency of generalized seizures in individuals 12 years of age or older with Lennox Gastaut Syndrome (LGS) who are refractory to antiseizure medications. The intent is to determine the feasibility and the optimal design of a subsequent pivotal study in order to expand the indication for use for the RNS System as a treatment for patien... Read More
Gender:
All
Ages:
12 years and above
Trial Updated:
02/08/2024
Locations: University of Alabama at Birmingham, Birmingham, Alabama +5 locations
Conditions: Epilepsy, Lennox Gastaut Syndrome, Lennox-Gastaut Syndrome, Intractable, Seizures, Seizures, Generalized
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Electrographic Seizure Management and Neurobehavioral Outcomes in Critically Ill Children
NCT03419260
Recruiting
Electrographic seizures are common in critically ill patients leading to increased use of resource-intense continuous EEG monitoring for seizure identification and management. When identified, electrographic seizures are generally treated with anti-seizure medications, but there are very limited data available regarding optimal treatment in terms of the efficacy or safety of specific anti-seizure medications or overall management strategies. This is a single-center prospective observational stu... Read More
Gender:
All
Ages:
Between 1 month and 18 years
Trial Updated:
01/29/2024
Locations: Children's Hospital of Philadelphia, Philadelphia, Pennsylvania
Conditions: Seizures
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Oxygen Toxicity: Mechanisms in Humans
NCT05761756
Recruiting
The goal of this clinical trial is to learn about the mechanisms of oxygen toxicity in scuba divers. The main questions it aims to answer are: How does the training of respiratory muscles affect oxygen toxicity? How do environmental factors, such as sleep deprivation, the ingestion of commonly utilized medications, and chronic exposure to carbon dioxide, impact the risk of oxygen toxicity? How does immersion in water affect the development of oxygen toxicity? Participants will be asked to do t... Read More
Gender:
All
Ages:
Between 18 years and 45 years
Trial Updated:
01/19/2024
Locations: Duke University Health Sustem, Durham, North Carolina
Conditions: Oxygen Toxicity, Hypercapnia, Seizures
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Transnasal Induction of Normothermia for Neurogenic Fever
NCT06038513
Recruiting
The objective of this study is to evaluate the efficacy of the COOLSTAT® Transnasal Thermal Regulating Device in reducing temperature in a population of febrile subjects who meet the inclusion/exclusion criteria.
Gender:
All
Ages:
Between 18 years and 85 years
Trial Updated:
11/29/2023
Locations: University of Maryland Medical Center, Baltimore, Maryland
Conditions: Stroke, Ischemic, Stroke Hemorrhagic, Seizures, Metabolic Encephalopathy
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Investigate Efficacy and Safety of Carisbamate as Adjunctive Treatment for Seizures Associated With LGS in Children and Adults
NCT05219617
Recruiting
The primary objective is to evaluate the efficacy of carisbamate (YKP509) as adjunctive treatment in reducing the number of drop seizures (tonic, atonic, and tonic-clonic) compared with placebo in pediatric and adult subjects (age 4-55 years) diagnosed with Lennox Gastaut Syndrome (LGS).
Gender:
All
Ages:
Between 4 years and 55 years
Trial Updated:
11/21/2023
Locations: Stanford University Hospital, Palo Alto, California +58 locations
Conditions: Seizures, Lennox Gastaut Syndrome
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Impact of Capturing Ictal Events With Ultra-long-term Ambulatory EEG Monitoring With Remote EEG Monitoring System.
NCT06027749
Recruiting
The goal of this clinical trial is to test Epitel's™ Remote EEG Monitoring System's (REMI™) ability to record electroencephalography (EEG) of seizure events in an ambulatory setting for extended periods (14 - 28 days) in patients presenting with questionable seizure characterization. The main questions it aims to answer are: • Can more seizure events be recorded in fourteen (14) days than can be recorded in three (3) days? • Do treating clinicians find clinical value in extended fourteen (14) -... Read More
Gender:
All
Ages:
Between 18 years and 70 years
Trial Updated:
10/24/2023
Locations: University of South Florida, Tampa, Florida +1 locations
Conditions: Epilepsy, Seizures
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