There are currently 21 active clinical trials seeking participants for Seizures research studies. The states with the highest number of trials for Seizures participants are Florida, California, Texas and New York.
Investigating Epilepsy: Screening and Evaluation
NCT03478852
Recruiting
Background: Epilepsy affects about 1 percent of the U.S. population. Most people with epilepsy respond well to medicine, but some do not. Researchers want people who have diagnosed or suspected epilepsy to participate in ongoing studies. They want to learn more about clinical care for epilepsy. They want fellows and residents to learn more about the care of people with epilepsy. Objectives: To learn more about seizures and find ways to best treat people with drug-resistant epilepsy. Eligibil... Read More
Gender:
ALL
Ages:
Between 8 years and 110 years
Trial Updated:
07/31/2025
Locations: National Institutes of Health Clinical Center, Bethesda, Maryland
Conditions: Seizures, Epilepsy, Epilepsy, Temporal Lobe, Partial Epilepsy
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Investigate Efficacy and Safety of Carisbamate as Adjunctive Treatment for Seizures Associated With LGS in Children and Adults
NCT05219617
Recruiting
The primary objective is to evaluate the efficacy of carisbamate (YKP509) as adjunctive treatment in reducing the number of drop seizures (tonic, atonic, and tonic-clonic) compared with placebo in pediatric and adult subjects (age 4-55 years) diagnosed with Lennox Gastaut Syndrome (LGS).
Gender:
ALL
Ages:
Between 4 years and 55 years
Trial Updated:
07/21/2025
Locations: Stanford University Hospital, Palo Alto, California +70 locations
Conditions: Seizures, Lennox Gastaut Syndrome
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Ketogenic Therapy Effects on Electrical and Metabolic Abnormalities in Epilepsy
NCT02216500
Recruiting
Approximately a fourth of children with seizures do not respond adequately to available therapy. Ketogenic therapy has a long history as treatment for intractable epilepsy, but there is no agreement concerning how it works and what is the best way to administer it. This natural history study will collect data pertaining to both questions.
Gender:
ALL
Ages:
50 years and below
Trial Updated:
07/08/2025
Locations: University of Florida, Gainesville, Florida
Conditions: Seizures
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Glioblastoma Remote Monitoring and Care - Research Protocol
NCT06129760
Recruiting
The purpose of this research is to learn more about how what the Apple watch measures, in terms of walking data, heart rate, breathing rate, and sleep habits, relates to how participants feel. During the course of the treatment, the symptoms participants experience change, and whether the Apple watch can detect these changes. Ultimately, this knowledge is being used to design proactive tools and signatures that can predict complications or symptom changes before they happen.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
07/08/2025
Locations: Cleveland Clinic Taussig Cancer institute, Case Comprehensive Cancer Center, Cleveland, Ohio
Conditions: Glioblastoma, Venous Thromboembolism, Seizures
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PeRampanel fOr Status ePilEpticus pRophylaxis Post-cardiac Arrest
NCT06401707
Recruiting
Brain injury is the main cause of death and disability for patients surviving cardiac arrest resuscitation and seizures are diagnosed in up to a third of these patients. The investigators are proposing a pilot randomized placebo-controlled clinical trial to evaluate the safety and feasibility of perampanel use for post-cardiac arrest status epilepticus (PCARSE) prevention after cardiac arrest.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
07/02/2025
Locations: Zuckerberg San Francisco General Hospital, San Francisco, California
Conditions: Heart Arrest, Seizures, Status Epilepticus
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De-identified UNMH EEG Corpus Database Creation With Fully De-identified Clinical Information
NCT05140265
Recruiting
This proposal outlines the steps required for the creation of a pilot database of EEG recordings and de-identified medical records from patients internally referred within the UNMH Comprehensive Epilepsy Center. The UNMH EEG Corpus would be the first database of its kind. Other public databases contain either patient EEG signals or medical records, but without both kinds of information, it is impossible to relate pre-treatment neurobiomarkers with post-treatment prognosis. The database will also... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
06/16/2025
Locations: University of New Mexico Health Science, Albuquerque, New Mexico
Conditions: Epilepsy, Status Epilepticus, Seizures
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buRst-supprESsion TO Stop Refractory Status Epilepticus Post-cardiac Arrest
NCT05851391
Recruiting
RESTORE is a randomized clinical trial investigating the safety and feasibility of using EEG treatment targets (burst suppression vs. seizure suppression) for post-cardiac arrest refractory status epilepticus treatment.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
05/12/2025
Locations: Zuckerberg San Francisco General Hospital, San Francisco, California
Conditions: Hypoxia-Ischemia, Brain, Heart Arrest, Status Epilepticus, Refractory Status Epilepticus, Seizures, Anoxic-Ischemic Encephalopathy, Anoxia-Ischemia, Cerebral
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Ear-Seizure Detection (EarSD) Study
NCT06598189
Recruiting
The proposed study is an investigator-initiated study that aims to measure the accuracy of a wearable seizure detection and prediction device (Ear-Seizure Detection Device (EarSD)) by simultaneous recording with conventional video-EEG (Electroencephalogram) on patients with epileptic seizures in the Epilepsy Monitoring Unit of the hospital.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
04/23/2025
Locations: Ummmc-Memorial Campus, Worcester, Massachusetts +1 locations
Conditions: Seizures, Epilepsy
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Oxygen Toxicity: Mechanisms in Humans
NCT05761756
Recruiting
The goal of this clinical trial is to learn about the mechanisms of oxygen toxicity in scuba divers. The main questions it aims to answer are: * How does the training of respiratory muscles affect oxygen toxicity? * How do environmental factors, such as sleep deprivation, the ingestion of commonly utilized medications, and chronic exposure to carbon dioxide, impact the risk of oxygen toxicity? * How does immersion in water affect the development of oxygen toxicity? Participants will be asked t... Read More
Gender:
ALL
Ages:
Between 18 years and 45 years
Trial Updated:
03/13/2025
Locations: Duke University Health Sustem, Durham, North Carolina
Conditions: Oxygen Toxicity, Hypercapnia, Seizures
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Transnasal Induction of Normothermia for Neurogenic Fever
NCT06038513
Recruiting
The objective of this study is to evaluate the efficacy of the COOLSTAT® Transnasal Thermal Regulating Device in reducing temperature in a population of febrile subjects who meet the inclusion/exclusion criteria.
Gender:
ALL
Ages:
Between 18 years and 85 years
Trial Updated:
02/12/2025
Locations: University of Maryland Medical Center, Baltimore, Maryland
Conditions: Stroke, Ischemic, Stroke Hemorrhagic, Seizures, Metabolic Encephalopathy
Register for Updates
Electrographic Seizure Management and Neurobehavioral Outcomes in Critically Ill Children
NCT03419260
Recruiting
Electrographic seizures are common in critically ill patients leading to increased use of resource-intense continuous EEG monitoring for seizure identification and management. When identified, electrographic seizures are generally treated with anti-seizure medications, but there are very limited data available regarding optimal treatment in terms of the efficacy or safety of specific anti-seizure medications or overall management strategies. This is a single-center prospective observational stu... Read More
Gender:
ALL
Ages:
Between 1 month and 18 years
Trial Updated:
02/03/2025
Locations: Children's Hospital of Philadelphia, Philadelphia, Pennsylvania
Conditions: Seizures
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Modulating Movement Intention Via Cortical Stimulation
NCT03233399
Recruiting
The purpose of this protocol is to learn about movement intention and volition. To improve such knowledge, investigators will conduct sub-studies using multiple non-invasive methodologies. These results could provide preliminary data for subsequent studies evaluating local and global efficacy of plasticity-inducing treatments for PMD symptoms.
Gender:
ALL
Ages:
Between 18 years and 65 years
Trial Updated:
01/28/2025
Locations: New York University School of Medicine, New York, New York
Conditions: Seizures, Seizure Disorder, Psychogenic Movement Disorder
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