There are currently 122 active clinical trials seeking participants for Spinal Cord Injuries research studies. The states with the highest number of trials for Spinal Cord Injuries participants are Texas, New York, Florida and Illinois.
Usability of the Adapted Rower for People With Spinal Cord Injury
Recruiting
The goal of this clinical trial is to examine usability of a locally built adaptive rower for people with spinal cord injury using an established and tested design. The main questions it aims to answer are: 1. What exercise intensity of activity do users achieve on the rower for steady state and interval rowing plans? 2. What assistance is required for setup and usage of the adaptive rower? 3. What do users think about the ease of use and what is their satisfaction with the adaptive rower? Pa... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
08/02/2024
Locations: Public Health Research Center, Columbia, South Carolina
Conditions: Spinal Cord Injuries
Multi-speed Ergonomic Wheelchair
Recruiting
Over one million Americans rely on their upper extremities for manual wheelchair propulsion. Shoulder overuse injuries are prevalent among manual wheelchair users and these injuries often result in shoulder pain. Severe shoulder pain can lead some wheelchair users to transition from manual to powered mobility, complicating transportation, and reducing independence in activities of daily living. This project will expand the understanding of a new wheelchair design that allows better positioning o... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
07/22/2024
Locations: Minneapolis VA Health Care System, Minneapolis, MN, Minneapolis, Minnesota
Conditions: Spinal Cord Diseases, Spinal Cord Injuries
Mild Intermittent Hypoxia and Its Multipronged Effect on Sleep Apnea
Recruiting
Mild intermittent hypoxia (IH) initiates sustained increases in chest wall and upper airway muscle activity in humans. This sustained increase is a form of respiratory plasticity known as long-term facilitation (LTF). Repeated daily exposure to mild IH that leads to the initiation of LTF of upper airway muscle activity could lead to increased stability of the upper airway. In line with PI's laboratory's mandate to develop innovative therapies to treat sleep apnea, this increased stability could... Read More
Gender:
ALL
Ages:
Between 18 years and 60 years
Trial Updated:
07/18/2024
Locations: John D Dingell VA Medical Center, Detroit, Michigan +1 locations
Conditions: Obstructive Sleep Apnea, Spinal Cord Injuries
Autologous Adipose Derived Mesenchymal Stem Cells for Spinal Cord Injury Patients
Recruiting
The purpose of this research study is to investigate the safety and potential therapeutic effects of autologous, culture-expanded, adipose derived mesenchymal stem cell intrathecal injections in the treatment of spinal cord injury.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
07/15/2024
Locations: Mayo Clinic in Rochester, Rochester, Minnesota
Conditions: Spinal Cord Injuries, Paralysis
Neuromodulation to Reduce Muscle Stiffness Following Spinal Cord Injury
Recruiting
People with spinal cord injuries may experience muscle tightness or uncontrollable spasms. This study is being conducted to investigate whether transcutaneous spinal stimulation can improve these symptoms. Transcutaneous spinal stimulation is a non-surgical intervention by applying electrical currents using skin electrodes over the lower back and belly. The investigators want to see how well the intervention of transcutaneous spinal stimulation performs by testing different levels of stimulatio... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
06/28/2024
Locations: Methodist Rehabilitation Center, Jackson, Mississippi +1 locations
Conditions: Spinal Cord Injuries, Spinal Cord Injury, Spinal Cord Injury Cervical, Spinal Cord Injury Thoracic
Transcutaneous Spinal Stimulation: Safety and Feasibility for Upper Limb Function in Children With Spinal Cord Injury
Recruiting
Children who suffer a spinal cord injury in the neck region have difficulty using their hands due to paralysis and/or weakness of their arms and hand muscles. The purpose of this project is to test the safety, comfort, and practicality of a new therapy that stimulates the spinal cord to facilitate activation of arm and hand muscles while practicing grasping, pinching, and reaching movements. The long-term goal is to provide better therapies that will improve the ability of children with SCI to m... Read More
Gender:
ALL
Ages:
Between 4 years and 18 years
Trial Updated:
06/20/2024
Locations: Department of Neurosurgery, Louisville, Kentucky
Conditions: Spinal Cord Injuries
Early Intervention for Information Processing Speed Deficits in Acute SCI: A Pilot Study
Recruiting
This study seeks to conduct a pilot study to test whether a cognitive training program can improve processing speed abilities in individuals with acute traumatic spinal cord injury.
Gender:
ALL
Ages:
Between 18 years and 65 years
Trial Updated:
06/19/2024
Locations: Kessler Foundation, East Hanover, New Jersey
Conditions: Spinal Cord Injuries, Cognitive Dysfunction, Cognitive Impairment, Acute Spinal Cord Injury
Closed-Loop Deep Brain Stimulation for Refractory Chronic Pain
Recruiting
Chronic pain affects 1 in 4 US adults, and many cases are resistant to almost any treatment. Deep brain stimulation (DBS) holds promise as a new option for patients suffering from treatment-resistant chronic pain, but traditional approaches target only brain regions involved in one aspect of the pain experience and provide continuous 24/7 brain stimulation which may lose effect over time. By developing new technology that targets multiple, complimentary brain regions in an adaptive fashion, the... Read More
Gender:
ALL
Ages:
Between 22 years and 80 years
Trial Updated:
06/17/2024
Locations: University of California, San Francisco, San Francisco, California
Conditions: Spinal Cord Injuries, Nerve Injury, Pain, Postoperative, Post Herpetic Neuralgia, Complex Regional Pain Syndromes, Post-Stroke Pain, Post Radiation Brain Injury, Post Radiation Plexopathy, Nerve Root Avulsion
Self-Management Program for AIS D SCI
Recruiting
About 25-51% of adults with acquired spinal cord injury (SCI) have "AIS D" SCI, the lowest severity grade of neurologic injury. Veterans with AIS D SCI generally have better outcomes in mobility, community integration, and employment. However, counterintuitively, they are also at higher risk of poor subjective well-being (SWB) and related psychosocial outcomes. Preliminary evidence suggests that poorer SWB in this group is associated with distinctive, modifiable factors such as less intensity of... Read More
Gender:
ALL
Ages:
All
Trial Updated:
06/12/2024
Locations: Hunter Holmes McGuire VA Medical Center, Richmond, VA, Richmond, Virginia
Conditions: Psychological Well-Being, Spinal Cord Injuries
Wrist Extensor MEP Up-conditioning for Individuals With Incomplete Spinal Cord Injury
Recruiting
The purpose of this study is to examine the relationship between common clinical assessments and measurements of the function of brain-spinal cord-muscle connections, and to examine the effects of training a brain-spinal cord-muscle response in individuals with incomplete spinal cord injury. A transcranial magnetic stimulator (TMS) is used for examining brain-to-muscle pathways. This stimulator produces a magnetic field for a very short period of time and indirectly stimulates brain cells with l... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
06/12/2024
Locations: Medical University of South Carolina, Charleston, South Carolina
Conditions: Spinal Cord Injuries, Quadriplegia
Deciphering Preserved Autonomic Function After Spinal Cord Injury
Recruiting
This study looks to characterize gradients of dysfunction in the autonomic nervous system after spinal cord injury. The autonomic nervous system plays key roles in regulation of blood pressure, skin blood flow, and bladder health- all issues that individuals with spinal cord injury typically suffer. Focusing on blood pressure regulation, the most precise metric with broad clinical applicability, the investigators will perform laboratory-based tests to probe the body's ability to generate autonom... Read More
Gender:
ALL
Ages:
Between 18 years and 50 years
Trial Updated:
06/11/2024
Locations: Mayo Clinic, Rochester, Minnesota
Conditions: Spinal Cord Injuries, Autonomic Imbalance, Autonomic Dysreflexia, Orthostatic Hypotension
A Pilot RCT to Improve Cognitive Processing Speed in Acute SCI
Recruiting
This study seeks conduct a pilot study to test whether a cognitive training program can improve processing speed abilities in individuals with acute traumatic spinal cord injury.
Gender:
ALL
Ages:
Between 18 years and 59 years
Trial Updated:
06/04/2024
Locations: Craig Hospital, Englewood, Colorado +2 locations
Conditions: Spinal Cord Injuries, Cognitive Dysfunction, Cognitive Impairment, Acute Spinal Cord Injury