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Spinal Cord Injuries Clinical Trials
A listing of 122 Spinal Cord Injuries clinical trials actively recruiting volunteers for paid trials and research studies in various therapeutic areas.
1 - 12 of 122
There are currently 122 active clinical trials seeking participants for Spinal Cord Injuries research studies. The states with the highest number of trials for Spinal Cord Injuries participants are Texas, New York, Florida and Illinois.
Featured Trial
Paid Clinical Studies Nationwide
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Nationwide clinical trials offered in your area. Some trials offering up to several thousand dollars in compensation for participation.
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Conditions:
Overweight
Overweight and Obesity
Obesity
Weight Loss
Morbid Obesity
Ketogenic Diet to Improve Neuro-recovery
Recruiting
The purpose of this project is to determine if 5 weeks of ketogenic (KD, high-fat) diet vs. standard diet (SD) significantly improves motor and sensory function, glycemic function, and functional independence in patients with spinal cord injury.
Gender:
ALL
Ages:
Between 19 years and 60 years
Trial Updated:
07/24/2025
Locations: Ohio State University Hospital, Columbus, Ohio
Conditions: Spinal Cord Injuries
Diet and Exercise Solutions to Postprandial Hypotension
Recruiting
The purpose of this study is to determine if a low glycemic diet and lower-body electrical stimulation can reduce postprandial hypotension in individuals with chronic spinal cord injury.
Gender:
ALL
Ages:
Between 18 years and 65 years
Trial Updated:
07/24/2025
Locations: Dodd Rehabilitation Hospital, Columbus, Ohio
Conditions: Spinal Cord Injuries
Effectiveness of the Collaborative Community Clinic for Persons With Spinal Cord Injury and Disease
Recruiting
The investigator is evaluating data stored on the Collaborative Community Clinic data repository (IRB #201811032). Researchers seek to evaluate the effectiveness of the Collaborative Community Clinic (CCC), an occupational therapy student experiential learning clinic for uninsured or under-insured people with spinal cord injury and disease (SCI/D), using participants' initial and follow-up assessment batteries.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
07/18/2025
Locations: Washington University, Saint Louis, Missouri
Conditions: Spinal Cord Injuries
Dose Escalation Study of EG110A, Administered by Intradetrusor Injections to Adults With Neurogenic Detrusor Overactivity-related Incontinence Following Spinal Cord Injury Who Regularly Perform Clean Intermittent Catheterization
Recruiting
This is a first-in-human, Phase 1b/2a, open-label, dose-escalation study of a single treatment course consisting of multiple intradetrusor injections of EG110A in male and female adult participants with Neurogenic Detrusor Overactivity (NDO)-related incontinence following Spinal Cord Injury (SCI), who have persistent incontinence after standard of care therapy and who perform Clear Intermittent Catheterization (CIC) on a regular basis.
Gender:
ALL
Ages:
Between 18 years and 75 years
Trial Updated:
07/15/2025
Locations: Rancho Los Amigos National Rehabilitation Center, Downey, California +3 locations
Conditions: Neurogenic Detrusor Overactivity, Spinal Cord Injuries
Transcutaneous Tibial Nerve Stimulation for Spinal Cord Injury Neurogenic Bladder
Recruiting
The purpose of this study is to determine if electric stimulation to the leg, called transcutaneous tibial nerve stimulation (TTNS), can improve bladder outcomes in acute spinal cord injury.
Gender:
ALL
Ages:
Between 18 years and 75 years
Trial Updated:
07/11/2025
Locations: MedStar National Rehabilitation Hospital, Washington, District of Columbia +1 locations
Conditions: Spinal Cord Injuries
Closed-Loop Deep Brain Stimulation for Refractory Chronic Pain
Recruiting
Chronic pain affects 1 in 4 US adults, and many cases are resistant to almost any treatment. Deep brain stimulation (DBS) holds promise as a new option for patients suffering from treatment-resistant chronic pain, but traditional approaches target only brain regions involved in one aspect of the pain experience and provide continuous 24/7 brain stimulation which may lose effect over time. By developing new technology that targets multiple, complimentary brain regions in an adaptive fashion, the... Read More
Gender:
ALL
Ages:
Between 22 years and 80 years
Trial Updated:
07/02/2025
Locations: University of California, San Francisco, San Francisco, California
Conditions: Spinal Cord Injuries, Nerve Injury, Pain, Postoperative, Post Herpetic Neuralgia, Complex Regional Pain Syndromes, Post-Stroke Pain, Post Radiation Brain Injury, Post Radiation Plexopathy, Nerve Root Avulsion
Multi-speed Ergonomic Wheelchair
Recruiting
Over one million Americans rely on their upper extremities for manual wheelchair propulsion. Shoulder overuse injuries are prevalent among manual wheelchair users and these injuries often result in shoulder pain. Severe shoulder pain can lead some wheelchair users to transition from manual to powered mobility, complicating transportation, and reducing independence in activities of daily living. This project will expand the understanding of a new wheelchair design that allows better positioning o... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
07/01/2025
Locations: Minneapolis VA Health Care System, Minneapolis, MN, Minneapolis, Minnesota
Conditions: Spinal Cord Diseases, Spinal Cord Injuries
Self-Management Program for AIS D SCI
Recruiting
About 25-51% of adults with acquired spinal cord injury (SCI) have "AIS D" SCI, the lowest severity grade of neurologic injury. Veterans with AIS D SCI generally have better outcomes in mobility, community integration, and employment. However, counterintuitively, they are also at higher risk of poor subjective well-being (SWB) and related psychosocial outcomes. Preliminary evidence suggests that poorer SWB in this group is associated with distinctive, modifiable factors such as less intensity of... Read More
Gender:
ALL
Ages:
All
Trial Updated:
06/25/2025
Locations: Hunter Holmes McGuire VA Medical Center, Richmond, VA, Richmond, Virginia
Conditions: Psychological Well-Being, Spinal Cord Injuries
Transcutaneous Spinal Stimulation and Exercise for Locomotion
Recruiting
Growing evidence indicates that electrical spinal cord stimulation improves motor functions both immediately and over the long term via modulating the excitability of spinal circuitry in patients with spinal cord injury. Recently, a novel, non-invasive, well-tolerated, and painless lumbosacral transcutaneous electrical stimulation strategy was demonstrated to be effective in improving lower limb motor function in participants with spinal cord injury. Our current project, cervical transcutaneous... Read More
Gender:
ALL
Ages:
Between 21 years and 70 years
Trial Updated:
06/20/2025
Locations: University of Washington, Seattle, Washington
Conditions: Spinal Cord Injuries
Deciphering Preserved Autonomic Function After Spinal Cord Injury
Recruiting
This study looks to characterize gradients of dysfunction in the autonomic nervous system after spinal cord injury. The autonomic nervous system plays key roles in regulation of blood pressure, skin blood flow, and bladder health- all issues that individuals with spinal cord injury typically suffer. Focusing on blood pressure regulation, the most precise metric with broad clinical applicability, the investigators will perform laboratory-based tests to probe the body's ability to generate autonom... Read More
Gender:
ALL
Ages:
Between 18 years and 50 years
Trial Updated:
06/18/2025
Locations: Mayo Clinic, Rochester, Minnesota
Conditions: Spinal Cord Injuries, Autonomic Imbalance, Autonomic Dysreflexia, Orthostatic Hypotension
Wrist Extensor MEP Up-conditioning for Individuals With Incomplete Spinal Cord Injury
Recruiting
The purpose of this study is to examine the relationship between common clinical assessments and measurements of the function of brain-spinal cord-muscle connections, and to examine the effects of training a brain-spinal cord-muscle response in individuals with incomplete spinal cord injury. A transcranial magnetic stimulator (TMS) is used for examining brain-to-muscle pathways. This stimulator produces a magnetic field for a very short period of time and indirectly stimulates brain cells with l... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
06/16/2025
Locations: Medical University of South Carolina, Charleston, South Carolina
Conditions: Spinal Cord Injuries, Quadriplegia
Influence of Spinal Stimulation Frequency on Spasticity, Motor Control, and Pain After Spinal Cord Injury
Recruiting
The goal of this study is to identify the effect of different types of noninvasive spinal stimulation on spasticity (involuntary muscle activity), muscle strength, and pain in people with spinal cord injury. The spinal stimulation consists of electrical stimulation applied through one electrode over the skin of the lower back and two electrodes over the stomach. Testing will include participating in measurements before the intervention, during intervention, and immediately after the intervention... Read More
Gender:
ALL
Ages:
16 years and above
Trial Updated:
06/13/2025
Locations: Shepherd Center, Inc., Atlanta, Georgia
Conditions: Spinal Cord Injuries
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