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Spinal Cord Injury Clinical Trials
A listing of 29 Spinal Cord Injury clinical trials actively recruiting volunteers for paid trials and research studies in various therapeutic areas.
1 - 12 of 29
There are currently 29 active clinical trials seeking participants for Spinal Cord Injury research studies. The states with the highest number of trials for Spinal Cord Injury participants are New York, Florida, Illinois and California.
Featured Trial
Paid Clinical Studies Nationwide
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Nationwide clinical trials offered in your area. Some trials offering up to several thousand dollars in compensation for participation.
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Conditions:
Overweight
Overweight and Obesity
Obesity
Weight Loss
Morbid Obesity
CBD for Lower Urinary Tract Dysfunction in Spinal Cord Injury
Recruiting
The goal of this feasibility study is to learn whether Cannabidiol (CBD) can improve urinary incontinence and other symptoms in people with recent spinal cord injury (SCI).
Participants will take Epidiolex (purified CBD) for 90 days
Gender:
ALL
Ages:
18 years and above
Trial Updated:
07/22/2025
Locations: University of Wisconsin - Madison, Madison, Wisconsin
Conditions: Supra-sacral Spinal Cord Injury, Spinal Cord Injury, Urinary Incontinence
Studying Rehabilitation Treatments Using Video to Improve Recovery for Adults With Physical Disabilities
Recruiting
This study aims to better understand how occupational therapists provide rehabilitation for adults recovering from stroke or spinal cord injury (SCI), with a focus on improving arm and hand function. Using video recordings of real outpatient therapy sessions, researchers will identify the key elements of treatment, such as the types of activities, the therapist's techniques, and how patients respond. The study will use the Rehabilitation Treatment Specification System (RTSS), a framework designe... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
07/22/2025
Locations: Ohio State Wexner Medical Center, Columbus, Ohio
Conditions: Stroke, Spinal Cord Injury, Occupational Therapy
Autonomic Effects of Stimulation in SCI
Recruiting
This study aims to determine the effects of transcutaneous spinal cord stimulation to increase blood pressure and use that device to increase power output and heart rate recovery during arm cycle ergometry. In addition, the investigators will see if the stimulation helps regulate body temperature when in a cool environment.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
07/01/2025
Locations: James J. Peters VA Medical Center, Bronx, NY, Bronx, New York
Conditions: Spinal Cord Injury
Virtual Peer Coaching in Manual Wheelchair Skills
Recruiting
The objective of this study is to determine the effectiveness of remote manual wheelchair skills training program. First, peer coaches will be enrolled and trained. Then, trainees will be enrolled into one of three interventions: intervention with remote feedback (Group 1), wait list control group (Group 2), and structured self-study (Group 3).
Gender:
ALL
Ages:
18 years and above
Trial Updated:
06/17/2025
Locations: University of Pittsburgh, Pittsburgh, Pennsylvania
Conditions: Wheelchair, Paraplegia, Spinal Cord Injury, Tetraplegia/Tetraparesis, Spinal Cord Injuries (SCI)
Cortical Recording and Stimulating Array Brain-Machine Interface
Recruiting
The purpose of this research study is to demonstrate the safety and efficacy of using two CRS Arrays (microelectrodes) for long-term recording of brain motor cortex activity and microstimulation of brain sensory cortex.
Gender:
ALL
Ages:
Between 22 years and 70 years
Trial Updated:
06/09/2025
Locations: University of Chicago, Chicago, Illinois +1 locations
Conditions: Tetraplegia, Spinal Cord Injury, Brainstem Stroke, Brachial Plexus Injury, Above Elbow Amputation
A Study to Evaluate the Safety of a Delivery Device for Administering LCTOPC1 in Participants With Spinal Cord Injury
Recruiting
The DOSED clinical study evaluates the safety and utility of a novel delivery device to deliver LCTOPC1, a cell therapy, to the spinal cord of patients with a spinal cord injury (SCI). LCTOPC1 is designed to replace or support cells that are absent or dysfunctional due to traumatic injury, with a goal to help improve the quality of life and restore or augment functional activity in persons suffering from a traumatic cervical or thoracic injuries.
Gender:
ALL
Ages:
Between 18 years and 65 years
Trial Updated:
06/09/2025
Locations: University of California, San Diego, La Jolla, California
Conditions: Spinal Cord Injury Cervical, Spinal Cord Injury Thoracic, Spinal Cord Injury, Acute, Spinal Cord Injury, Spinal Cord Injury, Chronic
Spine and Brain Stimulation for Movement Recovery After Cervical Spinal Cord Injury
Recruiting
Stimulation of the spinal cord and brain represents a new experimental therapy that may have potential to restore movement after spinal cord injury. While some scientists have begun to study the effect of electrical stimulation on patient's ability to walk and move their legs after lower spinal cord injury, the use of stimulation of the upper (cervical) spine to restore arm and hand function after cervical spinal cord injury remains less well explored. The investigators are doing this research s... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
06/03/2025
Locations: NewYork-Presbyterian Hospital / Columbia University Irving Medical Center (NYPH/CUIMC), New York, New York +1 locations
Conditions: Spinal Cord Injury, Spinal Cord Injury Cervical
Improve Dynamic Lateral Balance of Humans With SCI
Recruiting
This study is to test whether pelvis perturbation training paired with transcutaneous spinal direct current stimulation (tsDCS) will be effective in improving dynamic balance and locomotor function in humans with SCI. One group will receive pelvis perturbation training paired with tsDCS, one group will receive pelvis perturbation training paired with sham, and one group will receive treadmill training only.
Gender:
ALL
Ages:
Between 18 years and 65 years
Trial Updated:
05/28/2025
Locations: Abilitylab, Chicago, Illinois
Conditions: Spinal Cord Injury
Treating Central Neuropathic Pain With Low Dose Naltrexone for People With Spinal Cord Injury
Recruiting
The goal of this pilot clinical trial is to find out how well low dose naltrexone works for people with pain due to spinal cord injury. The main questions it aims to answer are: will low dose naltrexone reduce pain, and increase the quality of life for people with central neuropathic pain due to spinal cord injury.
Hypothesis 1: LDN will decrease the severity of CNP in adult patients with SCI as measured by the Neuropathic Pain Scale (NPS) Hypothesis 2: LDN will improve quality of life of patie... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
05/09/2025
Locations: Medical College of Wisconsin, Milwaukee, Wisconsin
Conditions: Central Neuropathic Pain, Spinal Cord Injury
At-Home Genital Nerve Stimulation for SCI Bowel
Recruiting
The purpose of this study is to test whether electrical stimulation of the skin in the pelvic area (near the genitals) can reduce the reflexes that cause bowel accidents in people with spinal cord injuries. Current bowel treatments either involve diet and medications or surgery. This study will evaluate whether electrical stimulation can be an alternate option for bowel management.
Researchers will:
* Use an FDA approved Transcutaneous Electrical Nerve Stimulation (TENS) device off-label
* Com... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
05/06/2025
Locations: MetroHealth Center for Rehabilitation Research, Cleveland, Ohio
Conditions: Spinal Cord Injury
Locomotor Training With Testosterone to Promote Bone and Muscle Health After Spinal Cord Injury
Recruiting
This pilot study will determine the feasibility of implementing a combinatory rehabilitation strategy involving testosterone replacement therapy (TRT) with locomotor training (LT; walking on a treadmill with assistance and overground walking) in men with testosterone deficiency and walking dysfunction after incomplete or complete spinal cord injury. The investigators hypothesize that LT+TRT treatment will improve muscle size and bone mineral density in men with low T and ambulatory dysfunction a... Read More
Gender:
MALE
Ages:
18 years and above
Trial Updated:
05/01/2025
Locations: North Florida/South Georgia Veterans Health System, Gainesville, Florida +1 locations
Conditions: Spinal Cord Injury, Spinal Cord Injuries, Trauma, Nervous System, Wounds and Injury, Central Nervous System Diseases, Spinal Cord Diseases, Gonadal Disorders, Endocrine System Diseases, Hypogonadism, Genital Diseases, Male, Spinal Cord Trauma, Injuries, Spinal Cord, Walking, Difficulty, Gait Disorders, Neurologic, Locomotion Disorder, Neurologic, Wounds and Injuries, Nervous System Diseases, Testosterone Deficiency, Androgen Deficiency, Hormone Deficiency
High Intensity Exercise and Improving Physical Activity Among People With Neurologic Dysfunction
Recruiting
The Hawks in Motion (HIM) High Intensity Exercise program is designed to implement the American Physical Therapy Clinical Practice Guidelines and American College of Sports Medicine recommendations for exercise for people with neurologic disability. Doctor of Physical Therapy (DPT) students administer the HIM High Intensity Exercise Program. A prior study evaluated the feasibility, safety, and efficacy of the HIM High Intensity Exercise Program and found it feasible, safe, and effective for 30 p... Read More
Gender:
ALL
Ages:
Between 8 years and 99 years
Trial Updated:
04/24/2025
Locations: University of Hartford, West Hartford, Connecticut
Conditions: Cerebral Palsy (CP), Stroke, Spinal Cord Injury, Traumatic Brain Injury, Charcot Marie Tooth Disease (CMT), Spina Bifida
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