There are currently 246 active clinical trials seeking participants for Stroke research studies. The states with the highest number of trials for Stroke participants are California, Florida, New York and Ontario.
The Feasibility, Usability, and Acceptability of Using the Oculus™ Virtual Reality Gaming Technology in Stroke Survivors for Upper Extremity and Cognitive Rehabilitation
Recruiting
The purpose of this study is to test the (a) feasibility, (b) usability, and (c) acceptability of using the Oculus Virtual Reality (VR) for chronic stroke survivors who have mild-moderate cognitive and unilateral arm impairment to administer upper extremity and cognitive rehabilitation, to calculate the change in upper extremity and cognition scores on standardized measurements per standard of care and to qualitatively explore the impact of engaging caregivers in supporting the stroke survivor's... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
11/28/2023
Locations: The University of Texas Health Science Center at Houston, Houston, Texas
Conditions: Stroke
Study Evaluating MyoRegulator® Treatment in Post-Stroke Upper Limb Spasticity
Recruiting
This is a multi-center, randomized, double-blind (patient and evaluator), sham-controlled study to be conducted in stroke patients with upper-extremity spasticity. The main objectives of this study are to evaluate the performance and safety of the MyoRegulator® device in active- versus sham-treated patients after 5 consecutive days of treatment. The MyoRegulator® device is a non-significant risk (NSR) investigational non-invasive neuromodulation device that uses multi-site direct current (multi-... Read More
Gender:
All
Ages:
Between 18 years and 85 years
Trial Updated:
11/28/2023
Locations: Spaulding Rehabilitation Hospital, Cambridge, Massachusetts +1 locations
Conditions: Muscle Spasticity, Stroke
Producing Increasingly Complex Themes Using Right-hemisphere Engagement (PICTURE) Implemented With Telemedicine
Recruiting
The investigators propose a pilot crossover trial of 2 behavioral language treatments, with randomized order of treatments and blinded assessors, to determine if a therapy designed to stimulate right hemisphere functions (Producing Increasingly Complex Themes Using Right-hemisphere Engagement Implemented with Telemedicine - PICTURE IT; described below) is more effective in improving discourse than a published computer delivered lexical treatment (shown previously to improve naming) in subacute p... Read More
Gender:
All
Ages:
Between 18 years and 99 years
Trial Updated:
11/28/2023
Locations: Johns Hopkins School of Medicine, Baltimore, Maryland
Conditions: Aphasia, Stroke
Operant Conditioning for Rehabilitation After Stroke
Recruiting
The purposes of this study include: To test if multiple upper extremity muscles represented within a discrete primary motor cortex site reflect existing muscle synergies after stroke. To test if altered muscle synergies and intermuscular coordination are malleable to motor evoked potential conditioning that induces corticospinal plasticity for the targeted muscle, wrist extensor carpi radialis
Gender:
All
Ages:
Between 40 years and 75 years
Trial Updated:
11/27/2023
Locations: University of Houston, Houston, Texas
Conditions: Stroke
Treatment With Endovascular Intervention for STroke Patients With Existing Disability
Recruiting
TESTED will compare the risks and benefits of endovascular thrombectomy (EVT) to medical management (no EVT) in ischemic stroke patients who have a blockage in one of the large blood vessels in the brain and have a moderate-to-severe disability prior to their stroke.
Gender:
All
Ages:
18 years and above
Trial Updated:
11/27/2023
Locations: HonorHealth, Phoenix, Arizona +11 locations
Conditions: Stroke, Stroke, Acute, Stroke, Ischemic
Virtual Reality Augmented Gait Adaptation in Stroke Survivors
Recruiting
The major problem in stroke survivors that is being addressed in this research project is walking asymmetry, i.e., difference between the legs during walking (e.g. steps on the more affected side are longer than the other). A potential solution to this problem is using new technology like virtual reality during walking training to make stroke survivors have a better sense of their asymmetry. A second problem that we aim to address in this study is whether asymmetry is accurately felt by the stro... Read More
Gender:
All
Ages:
21 years and above
Trial Updated:
11/22/2023
Locations: University of Nebraska - Omaha, Biomechanics Research Building, Omaha, Nebraska
Conditions: Stroke
Improving Aphasia Using Electrical Brain Stimulation
Recruiting
Language and communication are essential for almost every aspect of human life, but for people who have aphasia, a language processing disorder that can occur after stroke or brain injury, even simple conversations can become a formidable challenge. Speech and language therapy can help people recover their language ability, but often requires months or even years of therapy before a person is able to overcome these challenges. This research will investigate non-invasive brain stimulation as a wa... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
11/20/2023
Locations: Syracuse University, Syracuse, New York
Conditions: Stroke, Aphasia
Locomotor Function Following Transcutaneous Electrical Spinal Cord Stimulation in Individuals With Hemiplegic Stroke
Recruiting
This study has two interventional components, the first is a cross-over design and the second is a randomized control trial. Both will evaluate the effectiveness of transcutaneous (non-invasive) spinal cord stimulation on gait and balance function for individuals with hemiplegia due to stroke.
Gender:
All
Ages:
18 years and above
Trial Updated:
11/20/2023
Locations: Shirley Ryan AbilityLab, Chicago, Illinois
Conditions: Stroke
Concomitant Sensory Stimulation During Therapy to Enhance Hand Functional Recovery Post Stroke
Recruiting
The objective of this study is to determine if combining vibration with hand task practice is superior to hand task practice alone.
Gender:
All
Ages:
18 years and above
Trial Updated:
11/17/2023
Locations: Medical University of South Carolina, Charleston, South Carolina
Conditions: Stroke, Physical Disability
Comparing Different Rehabilitation Exercise Strategies for Improving Arm Recovery After Stroke
Recruiting
The purpose of this research study is to measure the effect of participating in extra arm exercise in addition to standard rehabilitation exercises in the Acute Rehabilitation Unit. This study will compare two different ways to perform the extra arm exercise. The first is following a customized program of hand and arm exercises that will be developed for study participants by an experienced rehabilitation therapist. The second is moving a participants arm back and forth when they are sitting in... Read More
Gender:
All
Ages:
Between 18 years and 84 years
Trial Updated:
11/16/2023
Locations: Rancho Research Institute, Downey, California +2 locations
Conditions: Stroke
Promoting Resilience in Stroke Survivor-carepartner Dyads (ReStoreD)
Recruiting
Affecting nearly 800,000 people in the US every year, stroke is a leading cause of long-term disability, and has serious consequences for stroke survivors and their carepartners. Our project uses a scientifically rigorous efficacy study to evaluate a remotely delivered 8-week dyadic (couples-based) positive psychology intervention to reduce emotional distress in stroke survivors and their carepartners. If successful, couples may be better emotionally equipped to cope with the sequelae of stroke,... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
11/09/2023
Locations: University of Utah, Salt Lake City, Utah
Conditions: Stroke, Depression, Anxiety, Coping Skills, Couples
Anticoagulation for New-Onset Post-Operative Atrial Fibrillation After CABG
Recruiting
The primary objective of this study is to evaluate the effectiveness (prevention of thromboembolic events) and safety (major bleeding) of adding oral anticoagulation (OAC) to background antiplatelet therapy in patients who develop new-onset post-operative atrial fibrillation (POAF) after isolated coronary artery bypass graft (CABG) surgery. All patients with a qualifying POAF event, who decline randomization, will be offered the option of enrollment in a parallel registry that captures their ba... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
11/08/2023
Locations: CHI St. Vincent, Arkansas, Little Rock, Arkansas +89 locations
Conditions: Atrial Fibrillation, Stroke, Bleeding