There are currently 251 active clinical trials seeking participants for Stroke research studies. The states with the highest number of trials for Autism participants are California, Florida, New York and Ontario.
EMG Controlled Device in Acute Rehabilitation After Acute Stroke
NCT04599036
Recruiting
Stroke is a medically relevant problem for the aging population. Individuals with stroke experience a high amount of arm functional deficits despite receiving rehabilitation. Functional deficits can be improved by combining rehabilitation with innovative rehabilitative tools that target the brain mechanisms that guide the recovery early after stroke. This study aims to explore the feasibility of implementing an EMG controlled device in the acute rehabilitation for stroke survivors with severe ar... Read More
Gender:
All
Ages:
Between 18 years and 90 years
Trial Updated:
09/12/2023
Locations: Louis Stokes VA Medical Center, Cleveland, OH, Cleveland, Ohio
Conditions: Stroke
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Optimizing Training in Severe Post-Stroke Walking Impairment
NCT04721860
Recruiting
Difficulty walking is common after a stroke. Although physical rehabilitation helps a little with the improvement of walking ability, recovery is usually incomplete. The purpose of this study is to explore how two different treadmill training approaches influence walking speed, symmetry, and balance in people with chronic severe stroke-related walking impairment. The two approaches involve either forward or backwards treadmill training. This study will look at changes in walking performance and... Read More
Gender:
All
Ages:
Between 18 years and 80 years
Trial Updated:
09/11/2023
Locations: University of Cincinnati College of Medicine, Cincinnati, Ohio
Conditions: Stroke, Chronic Stroke, Walking, Difficulty, Gait, Hemiplegic
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A Novel Brain Stimulation for Bimanual Motor Function and Control in Chronic Stroke
NCT05381740
Recruiting
The long-term goal of this project is to develop and test upper Iimb rehabilitation interventions that can improve bimanual motor function, or the ability to use both arms and hands together, for stroke survivors with moderate to severe impairment. This study will utilize a novel method of non-invasive brain stimulation in conjunction with upper limb training given for 12 visits over a period of 6 weeks. The study will include the following site visits: Eligibility Screening and Informed Cons... Read More
Gender:
All
Ages:
Between 18 years and 90 years
Trial Updated:
07/27/2023
Locations: Lerner Research Institute, Cleveland Clinic Foundation, Cleveland, Ohio
Conditions: Stroke
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Implant for Walking After Stroke
NCT05740540
Recruiting
This is a device study that will evaluate the effect of an implanted stimulator on improving walking in stroke survivors. There are two phases in the study: 1) Screening - this phase determines if the individual is a good candidate to receive an implanted system, 2) Implantation, controller development, and evaluation - this phase includes installing the device and setting the individual up for home use, creating advanced controllers for walking and evaluating the effect of the device over sever... Read More
Gender:
All
Ages:
Between 21 years and 75 years
Trial Updated:
06/27/2023
Locations: Louis Stokes Cleveland Veterans Affairs Medical Center, Cleveland, Ohio +1 locations
Conditions: Stroke, Hemiplegia, Gait, Hemiplegic
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Imaging Post-Stroke Recovery: Using MEG to Evaluate Cognition
NCT04188522
Recruiting
This is a study using magnetoencephalography (MEG) to look at recovery in those with minor stroke. The investigators know that these individuals report difficulties in attention, concentration, multi-tasking, energy level, and processing speed that appear to be independent of lesion size or location. The underlying pathophysiology is unclear; however, anecdotally, many individuals are significantly improved by 6 months post-stroke. One hypothesis is that a single lesion, regardless of size, may... Read More
Gender:
All
Ages:
Between 18 years and 100 years
Trial Updated:
04/29/2024
Locations: Johns Hopkins Bayview Medical Center, Baltimore, Maryland
Conditions: Stroke, Stroke Sequelae, Stroke/Brain Attack
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Constraint-Induced Movement Therapy Plus Sensory Components After Stroke
NCT05515237
Recruiting
Constraint-Induced Movement Therapy or CI Therapy is a form of treatment that systematically employs the application of selected behavioral techniques delivered in intensive treatment over consecutive day with the following strategies utilized: behavioral strategies are implemented to improve the use of the more- affected limb in life situation called a Transfer Package (TP), motor training using a technique called shaping to make progress in successive approximations, repetitive, task oriented... Read More
Gender:
All
Ages:
Between 18 years and 89 years
Trial Updated:
04/29/2024
Locations: University of Alabama at Birmingham, Birmingham, Alabama
Conditions: CVA (Cerebrovascular Accident), Stroke, Upper Extremity Paresis
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Constraint-Induced Movement Therapy for Adults Post-Stroke With Mild Upper Extremity Impairment
NCT05492513
Recruiting
Constraint-Induced Therapy (CI Therapy) is a behavioral approach to neurorehabilitation and consists of multi-components that have been applied in a systematic method to improve the use of the limb or function addressed in the intensive treatment. CI Therapy for the more-affected upper extremity (UE) post-stroke is administered in daily treatment sessions over consecutive weekdays. Sessions include motor training with repeated, timed trials using a technique called shaping, a set of behavioral s... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
04/29/2024
Locations: University of Alabama at Birmingham, Birmingham, Alabama
Conditions: CVA (Cerebrovascular Accident), Stroke, Upper Extremity Paresis
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Biomarkers of Reaction To HIIT Exercise
NCT06059872
Recruiting
Stroke survivors with lower limb disability can improve their walking speed with high-intensity interval training (HIIT) rehabilitation therapy. However, some individuals may not respond to HIIT even when fully adherent to the program. To address this, the investigators propose to build a predictive model that identifies if a Veteran with chronic subcortical stroke will improve their walking speed with HIIT by incorporating blood lactate as an early predictor of exercise response, and inhibitory... Read More
Gender:
All
Ages:
Between 18 years and 80 years
Trial Updated:
04/26/2024
Locations: Atlanta VA Medical and Rehab Center, Decatur, GA, Decatur, Georgia
Conditions: Stroke, Stroke Rehabilitation, Lower Extremity Weakness, Spastic, Walking, Difficulty
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Comparison of Anti-coagulation and Anti-Platelet Therapies for Intracranial Vascular Atherostenosis
NCT05047172
Recruiting
The primary goal of the trial is to determine if the experimental arms (rivaroxaban or ticagrelor or both) are superior to the clopidogrel arm for lowering the 1-year rate of ischemic stroke, intracerebral hemorrhage, or vascular death.
Gender:
All
Ages:
30 years and above
Trial Updated:
04/26/2024
Locations: University of Alabama Hospital, Birmingham, Alabama +108 locations
Conditions: Intracranial Arteriosclerosis, Stroke
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Treatment of Acute Ischemic Stroke (ReMEDy2 Trial)
NCT05065216
Recruiting
This is a Phase 2/3 study evaluating the safety and efficacy of DM199 in treating participants presenting within 24 hours of Acute Ischemic Stroke (AIS) onset for whom fibrinolytics and/or a catheter-based procedure, mechanical thrombectomy (MT), are not medically appropriate or available due to constraints of clot location, comorbidity risks, and/or time from estimated onset of stroke. The double-blinded study will be randomized, placebo controlled at up to approximately 100 sites.
Gender:
All
Ages:
18 years and above
Trial Updated:
04/25/2024
Locations: Washington Regional Medical Center, Fayetteville, Arkansas +13 locations
Conditions: Acute Stroke, Ischemic Stroke, Stroke
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Tracking Post-stroke Walking Improvements From the Clinic Into the Home
NCT05454007
Recruiting
The purpose of this proposal is to use novel video-based movement tracking technology to measure gait quality after stroke - in the home. Current rehabilitation practice assesses walking in the highly controlled 'ideal' clinical environment. The implicit assumption by clinicians and researchers is that the way people walk in the clinic (their best capacity) reflects the way they walk in the real-world (true performance). With advances in computer vision and development of pose estimation algorit... Read More
Gender:
All
Ages:
Between 21 years and 90 years
Trial Updated:
04/25/2024
Locations: Western University of Health Sciences, Lebanon, Oregon
Conditions: Stroke
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EVOLVE-MI: EVOLocumab Very Early After Myocardial Infarction
NCT05284747
Recruiting
The primary objective of this study is to evaluate the effectiveness of early treatment with evolocumab plus routine lipid management vs routine lipid management alone when administered in the acute setting to reduce myocardial infarction, ischemic stroke, arterial revascularization, and all-cause death in subjects hospitalized for an acute myocardial infarction (non-ST-segment elevation myocardial infarction [NSTEMI] and ST-segment elevation myocardial infarction [STEMI]).
Gender:
All
Ages:
Between 18 years and 99 years
Trial Updated:
04/24/2024
Locations: University of Alabama at Birmingham, Birmingham, Alabama +119 locations
Conditions: Cardiovascular Disease, Myocardial Infarction, Stroke, Coronary Revascularization
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