There are currently 246 active clinical trials seeking participants for Stroke research studies. The states with the highest number of trials for Stroke participants are California, Florida, New York and Ontario.
Imaging Post-Stroke Recovery: Using MEG to Evaluate Cognition
NCT04188522
Recruiting
This is a study using magnetoencephalography (MEG) to look at recovery in those with minor stroke. The investigators know that these individuals report difficulties in attention, concentration, multi-tasking, energy level, and processing speed that appear to be independent of lesion size or location. The underlying pathophysiology is unclear; however, anecdotally, many individuals are significantly improved by 6 months post-stroke. One hypothesis is that a single lesion, regardless of size, may... Read More
Gender:
All
Ages:
Between 18 years and 100 years
Trial Updated:
04/29/2024
Locations: Johns Hopkins Bayview Medical Center, Baltimore, Maryland
Conditions: Stroke, Stroke Sequelae, Stroke/Brain Attack
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Biomarkers of Reaction To HIIT Exercise
NCT06059872
Recruiting
Stroke survivors with lower limb disability can improve their walking speed with high-intensity interval training (HIIT) rehabilitation therapy. However, some individuals may not respond to HIIT even when fully adherent to the program. To address this, the investigators propose to build a predictive model that identifies if a Veteran with chronic subcortical stroke will improve their walking speed with HIIT by incorporating blood lactate as an early predictor of exercise response, and inhibitory... Read More
Gender:
All
Ages:
Between 18 years and 80 years
Trial Updated:
04/26/2024
Locations: Atlanta VA Medical and Rehab Center, Decatur, GA, Decatur, Georgia
Conditions: Stroke, Stroke Rehabilitation, Lower Extremity Weakness, Spastic, Walking, Difficulty
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Tracking Post-stroke Walking Improvements From the Clinic Into the Home
NCT05454007
Recruiting
The purpose of this proposal is to use novel video-based movement tracking technology to measure gait quality after stroke - in the home. Current rehabilitation practice assesses walking in the highly controlled 'ideal' clinical environment. The implicit assumption by clinicians and researchers is that the way people walk in the clinic (their best capacity) reflects the way they walk in the real-world (true performance). With advances in computer vision and development of pose estimation algorit... Read More
Gender:
All
Ages:
Between 21 years and 90 years
Trial Updated:
04/25/2024
Locations: Western University of Health Sciences, Lebanon, Oregon
Conditions: Stroke
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Pharmacy-led Transitions of Care Intervention to Improve Medication Adherence
NCT06374277
Recruiting
Socioeconomically disadvantaged populations with multiple chronic conditions have high rates of nonadherence to essential chronic disease medications after hospital discharge. Medication nonadherence after hospital discharge is significantly associated with increased mortality and higher rates of readmissions and costs among these patients. Major patient-reported barriers to essential medication use after hospital discharge among low-income individuals are related to social determinants of healt... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
04/23/2024
Locations: University of Tennessee Medical Center, Knoxville, Tennessee +1 locations
Conditions: Diabetes, Hypertension, High Cholesterol/Hyperlipidemia, Coronary Artery Disease, Congestive Heart Failure, Chronic Lung Disease, Chronic Kidney Diseases, Arrythmia, Stroke, Depression, Anxiety, Pulmonary Embolism, Heart Attack
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Augmenting a Post-Stroke Wellness Program With Respiratory Muscle Training
NCT05819333
Recruiting
The goal of this clinical trial is to test the hypothesis that combined Respiratory Muscle Training and a Stroke Wellness Program is more effective than a Stroke Wellness Program alone for stroke survivors with and without a smoking exposure history. Participants will participant in a Stroke Wellness Program consisting of strengthening, cardiovascular and flexibility training program plus respiratory exercise for 24 sessions (3x/week for 8 weeks). Researchers will compare outcomes to those ran... Read More
Gender:
All
Ages:
Between 18 years and 95 years
Trial Updated:
04/17/2024
Locations: Brooks Rehabilitation Hospital, Jacksonville, Florida
Conditions: Stroke
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Exercise Primed Stroke Rehabilitation
NCT04877444
Recruiting
Stroke is a leading cause of disability in the U.S. and many Veteran stroke survivors live with severe disability. Despite recent advances in rehabilitation treatments many stroke survivors have persistent physical and mental difficulties such as reduced physical and cognitive function and depression. Developing innovative treatments that address these problems is necessary to improve long-term outcomes for stroke survivors. Aerobic exercise (AEx) can improve physical and cognitive function, and... Read More
Gender:
All
Ages:
Between 50 years and 90 years
Trial Updated:
04/17/2024
Locations: Ralph H. Johnson VA Medical Center, Charleston, SC, Charleston, South Carolina
Conditions: Stroke
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StrokeCog-BBB to Study Cognitive Outcomes Following Stroke
NCT06116630
Recruiting
The goal of this observational study is to learn about cognitive outcomes in stroke patients. The main question it aims to answer are: 1. Is blood-brain barrier permeability compromised for years after stroke, 2. Is a blood biomarker of imbalanced angiogenesis dysregulated in chronic stroke and 3. Are there biomarkers that separately or together predicts cognitive decline after stroke, and are other MRI, blood, and clinical characteristics that are associated. Participants will undergo cognitive... Read More
Gender:
All
Ages:
Between 45 years and 90 years
Trial Updated:
04/16/2024
Locations: Stanford University Hospital, Palo Alto, California
Conditions: Stroke
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Improving Blood Pressure Control in Stroke Patients by Increasing Access to a Home Blood Pressure Monitor
NCT05730465
Recruiting
The goal of this clinical trial is to learn whether providing teaching with a low-cost device can help to improve blood pressure, health outcomes, patient self-efficacy without exacerbating inequity between advantaged and disadvantaged patients. The main question[s] it aims to answer are: Does providing a free home blood pressure cuff improve control of hypertension? Does providing a free home blood pressure cuff have a greater impact on control of hypertension in disadvantaged populations? Do... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
04/16/2024
Locations: Stanford University Hospital, Palo Alto, California
Conditions: Hypertension, Stroke, TIA, Vascular Diseases
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Amplatzer Amulet LAAO vs. NOAC
NCT04226547
Recruiting
The objective of this trial is to evaluate the safety and effectiveness of the Amulet LAA occluder compared to NOAC therapy in patients with non-valvular AF at increased risk for ischemic stroke and who are recommended for long-term NOAC therapy. The clinical investigation is a prospective, randomized, multicenter active control worldwide trial. Subjects will be randomized in a 1:1 ratio between the Amulet LAA occlusion device ("Device Group") and a commercially available NOAC medication ("Cont... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
04/15/2024
Locations: University Hospital - Univ. of Alabama at Birmingham (UAB), Birmingham, Alabama +126 locations
Conditions: Atrial Fibrillation, Stroke, Bleeding
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Neurologic Stem Cell Treatment Study
NCT02795052
Recruiting
This is a human clinical study involving the isolation of autologous bone marrow derived stem cells (BMSC) and transfer to the vascular system and inferior 1/3 of the nasal passages in order to determine if such a treatment will provide improvement in neurologic function for patients with certain neurologic conditions. http://mdstemcells.com/nest/
Gender:
All
Ages:
18 years and above
Trial Updated:
04/12/2024
Locations: MD Stem Cells, Westport, Connecticut +2 locations
Conditions: Neurologic Disorders, Nervous System Diseases, Neurodegenerative Diseases, Neurological Disorders, Stroke, Traumatic Brain Injury, Cadasil, Chronic Traumatic Encephalopathy, Cerebral Infarction, Cerebral Ischemia, Cerebral Stroke, Cerebral Hemorrhage, Parkinson, Multi-System Degeneration, MSA - Multiple System Atrophy, Progressive Supranuclear Palsy, ALS, Amyotrophic Lateral Sclerosis, Neuropathy, Diabetic Neuropathies, Alzheimer Disease, Dementia, Frontotemporal Dementia, Lewy Body Disease, Cognitive Impairment, Lewy Body Variant of Alzheimer Disease
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Mediterranean-DASH Intervention for Neurodegenerative Delay (MIND) Diet in Stroke Patients Patients
NCT04337255
Recruiting
To test the effects of a 2- to 3-year intervention of the MIND diet versus usual post-stroke care on cognitive decline, the characteristic feature of dementia, and on brain biomarkers of Alzheimer's Disease (AD) and vascular disease in a Phase Ill randomized controlled trial of 500 patients hospitalized for acute ischemic stroke, aged 55 years or older, and without dementia who are discharged home following hospitalization.
Gender:
All
Ages:
55 years and above
Trial Updated:
04/10/2024
Locations: Rush University Medical Center, Chicago, Illinois
Conditions: Cognitive Decline, Dementia, Vascular, Alzheimer Disease, Dementia, Stroke
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Brain State-dependent PCMS in Chronic Stroke
NCT04830163
Recruiting
After stroke, people often have difficulty using their hands. Combined brain and nerve stimulation can strengthen the neural pathways that control hand function. In this study, we will deliver combined brain and nerve stimulation during specific time windows that increase activation of neural pathways underlying hand function. We will compare the effects of combined brain and nerve stimulation during these optimal time windows to the effects of combined brain and nerve stimulation applied during... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
04/10/2024
Locations: University of Texas at Austin, Austin, Texas
Conditions: Stroke
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