There are currently 237 active clinical trials seeking participants for Stroke research studies. The states with the highest number of trials for Stroke participants are California, Florida, New York and Ontario.
Variable Intensive Early Walking Post-Stroke - 2 (VIEWS-2)
NCT05727930
Recruiting
The proposed research will evaluate the individual and combined effects of task-specificity and intensity of rehabilitation interventions on locomotor function, community mobility and quality of life in patients with subacute (1-6 months) post-stroke.
Gender:
ALL
Ages:
Between 18 years and 85 years
Trial Updated:
03/10/2025
Locations: Rehabilitation Hospital of Indiana, Indianapolis, Indiana
Conditions: Stroke
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Assessment of a Physio-neuro Platform (SynPhNe) for Home-based Retraining of Hand Function in Stroke Survivors
NCT02896348
Recruiting
The goal of this study is to: 1. Assess the usability of the SynPhNe device in a home environment. 2. Evaluate the efficacy of the SynPhNe home use device to improve motor hand function in chronic stroke subjects as compared to standard care alone.
Gender:
ALL
Ages:
Between 21 years and 80 years
Trial Updated:
03/06/2025
Locations: Spaulding Rehabilitation Hospital, Boston, Massachusetts
Conditions: Stroke, Hemiparesis
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Exercise and Motor Learning After Stroke (Study #3)
NCT03726047
Recruiting
Subjects with chronic stroke (\> 6 months post-stroke) will learn a new walking pattern through distorted visual feedback. Retention of the pattern will be tested without visual feedback immediately after learning and 24 hours later. Subjects will be randomly assigned to the control group or the exercise group. The control group will simply complete the learning task. The exercise group will complete 5 minutes of exercise immediately following the first retention test to test for the effects of... Read More
Gender:
ALL
Ages:
Between 18 years and 85 years
Trial Updated:
03/04/2025
Locations: University of Delaware, Newark, Delaware
Conditions: Stroke
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To Develop a Walking Exercise Program for Non-ambulatory Stroke Survivors
NCT06247553
Recruiting
The goal of this clinical trial is to test a gait (walking) training program in non-ambulatory (unable to walk) chronic stroke survivors. The main question it aims to answer is: • Will gait training improve the cardiovascular system in non-ambulatory chronic stroke survivors better than a sitting leg cycling exercise? Participants will walk on a treadmill with a partial body-weight support system and the gait training device. Researchers will compare with a leg-cycling exercise to see if there... Read More
Gender:
ALL
Ages:
Between 18 years and 80 years
Trial Updated:
03/03/2025
Locations: University of Kansas Medical Center, Kansas City, Kansas
Conditions: Stroke, Walking, Difficulty, Cardiovascular Injury
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Post-stroke Perturbation Training
NCT04855032
Recruiting
Following a stroke, many individuals have a high risk of falls, which can negatively influence quality of life. Unfortunately, current treatments have not effectively addressed this problem. This study investigates whether two methods of delivering mechanical perturbations during walking have the potential to improve post-stroke walking balance and reduce real-world fall incidence.
Gender:
ALL
Ages:
21 years and above
Trial Updated:
03/03/2025
Locations: Medical University of South Carolina, Charleston, South Carolina
Conditions: Stroke
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R3THA Rehabilitation Feasibility and Usability Study
NCT06854978
Recruiting
The purpose of this study is to assess how the Rehabilitation Technologies for Hand and Arm (R3THA) device can be used for rehabilitation of people with stroke. the study will evaluate the feasibility of R3THA as outpatient telerehabilitation administered by trained clinicians to individuals with stroke.
Gender:
ALL
Ages:
Between 20 years and 80 years
Trial Updated:
02/28/2025
Locations: Kessler Foundation, West Orange, New Jersey
Conditions: Stroke
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Mapping Corticoreticulospinal Motor Control in Chronic Hemiparetic Stroke
NCT06598150
Recruiting
This study uses functional magnetic resonance imaging to map neural activity throughout the central nervous system during a shoulder abduction task to characterize what motor pathways are being used post-stroke.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
02/28/2025
Locations: Northwestern University, Chicago, Illinois
Conditions: Stroke, Hemiparesis
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Cycle and Stroke With Biofeedback for Power Symmetry
NCT06857916
Recruiting
To determine changes in power symmetry, gait symmetry, and functional outcomes for participants' poststroke (Inpatient Rehabilitation Facility) after participating in an intervention using a recumbent cycle with power biofeedback (BFB). To determine how this intervention can impact gait asymmetry, a common disorder poststroke secondary to hemiparesis. Gait asymmetry is a difficult impairment to treat because it is difficult for both therapists and patients to perceive. Training with BFB allows f... Read More
Gender:
ALL
Ages:
Between 18 years and 70 years
Trial Updated:
02/27/2025
Locations: University Health, Neilsen Rehabilitation Hospital, Salt Lake City, Utah
Conditions: Stroke
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Locomotor Recovery and Compensation Post-stroke (LRC)
NCT05081713
Recruiting
The proposed research will characterize of the time course of neurological and locomotor recovery as well as development of compensatory strategies throughout sub-acute and chronic phases post stroke. In addition, we will also investigate the extent to which measures of recovery and compensation are malleable and can be altered with specific interventions in both the early and late stages post-stroke. Delineation of the time course of development and magnitude of patterns of recovery and compens... Read More
Gender:
ALL
Ages:
Between 18 years and 85 years
Trial Updated:
02/26/2025
Locations: Rehabilitation Hospital of Indiana, Indianapolis, Indiana
Conditions: Stroke
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Amplatzer Amulet LAAO Vs. NOAC
NCT04226547
Recruiting
The objective of this trial is to evaluate the safety and effectiveness of the Amulet LAA occluder compared to NOAC therapy in patients with non-valvular AF at increased risk for ischemic stroke and who are recommended for long-term NOAC therapy. The clinical investigation is a prospective, randomized, multicenter active control worldwide trial. Subjects will be randomized in a 1:1 ratio between the Amulet LAA occlusion device ("Device Group") and a commercially available NOAC medication ("Cont... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
02/25/2025
Locations: University Hospital - Univ. of Alabama at Birmingham (UAB), Birmingham, Alabama +131 locations
Conditions: Atrial Fibrillation, Stroke, Bleeding
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Transcranial Magnetic Stimulation + Language Therapy to Treat Mild Aphasia
NCT06842745
Recruiting
The goal of this clinical trial is to determine if Transcranial Magnetic Stimulation (TMS) combined with Speech-Language Therapy (SLT) is an effective treatment for mild aphasia in persons with chronic stroke. The main questions this study aims to answer are: 1. Can TMS combined with SLT improve conversational speech and comprehension? 2. Can we identify specific behavioral and biological characteristics that would benefit most from the TMS and SLT treatment? Researchers will compare real TMS... Read More
Gender:
ALL
Ages:
Between 40 years and 85 years
Trial Updated:
02/18/2025
Locations: University of Pennsylvania, Philadelphia, Pennsylvania
Conditions: Aphasia, Stroke, Aphasia Following Cerebral Infarction, Aphasia, Acquired
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rTMS for Post-stroke Fatigue
NCT05584124
Recruiting
This experimental trial is investigating the use of magnetic stimulation of the brain as a possible treatment for people with post-stroke fatigue. Fatigue is a common condition after a stroke and can negatively impact an individual's ability to perform desired social and physical activities. Magnetic stimulation of the brain has been shown to improve signs and symptoms of related psychological (e.g., depression) conditions. Participants in this trial will receive a type of magnetic stimulation c... Read More
Gender:
ALL
Ages:
Between 35 years and 80 years
Trial Updated:
02/14/2025
Locations: Ralph H. Johnson VA Medical Center, Charleston, SC, Charleston, South Carolina
Conditions: Stroke, Stroke, Chronic, Fatigue
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