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Substance-Related Disorders Clinical Trials
A listing of 23 Substance-Related Disorders clinical trials actively recruiting volunteers for paid trials and research studies in various therapeutic areas.
13 - 23 of 23
There are currently 23 active clinical trials seeking participants for Substance-Related Disorders research studies. The states with the highest number of trials for Substance-Related Disorders participants are California, New York, Washington and Massachusetts.
Featured Trial
Paid Clinical Studies Nationwide
Recruiting
Nationwide clinical trials offered in your area. Some trials offering up to several thousand dollars in compensation for participation.
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Recruiting
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Conditions:
Overweight
Overweight and Obesity
Obesity
Weight Loss
Morbid Obesity
Whole Health in VA Mental Health: Omnis Salutis
Recruiting
Recent Veterans of the Afghanistan and Iraq conflicts are presenting in VA care with high rates of posttraumatic stress disorder (PTSD), depression, anxiety, and substance use disorders. Difficulties with social relationships and community reintegration are common functional impairments with these disorders. VA is transforming to a Whole Health, patient-centered system of care that will address these issues as part of health care. In a previous study, Omnis Salutis (OS) was developed with Vetera... Read More
Gender:
ALL
Ages:
Between 18 years and 65 years
Trial Updated:
02/06/2025
Locations: Rocky Mountain Regional VA Medical Center, Aurora, CO, Aurora, Colorado +1 locations
Conditions: Stress Disorders, Post-Traumatic, Depressive Disorder, Anxiety Disorders, Substance-Related Disorders
Phase II: Scalable Digital Delivery of CRAFT Training for Professionals to Maximize Treatment Rates of OUD in Families
Recruiting
The goal of this project is to demonstrate digital training efficacy at scale and commercial readiness.
This pilot project will advance piloted digital training programs for CRAFT and maximize scalability. In this project, investigators will:
Aim 1: Optimize the digital CRAFT training product based on data and feedback from the pilot and commercialization advisors.
Aim 2: Conduct a fully powered randomized control trial of 3 levels of digital training (Level 1 - Digital tutorial only \[T\]; L... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
11/11/2024
Locations: We The Village, Inc., New York, New York
Conditions: Community Reinforcement And Family Training, Family Health, Substance-Related Disorders
Impact of Work Activity on SUD Outcomes
Recruiting
To date, there are no studies of the therapeutic effects of varied work-focused programs in Veterans undergoing outpatient substance use disorder (SUD) treatment. The investigators propose a randomized clinical trial to test the effects of work-focused programs on improving sobriety and other clinical outcomes in Veterans early in the course of recovery from SUD. Veterans will be randomized to either receive or not receive referral for work-focused therapeutic programs. Primary aim is to examine... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
10/09/2024
Locations: VA Connecticut Healthcare System West Haven Campus, West Haven, CT, West Haven, Connecticut
Conditions: Substance-related Disorders
Mobile Technologies Extending Reach of Primary Care for Substance Use Disorders
Recruiting
The goal of this clinical trial is to evaluate efficacy of our enhanced version of the CHESS Health eIntervention in a clinical setting for those with moderate risk drug or alcohol use and those at high risk or with Substance Use Disorder (SUD) as measured by the ASSIST and the AUDIT assessment tools. The clinical trial is designed to determine whether SBIRT/eIntervention is significantly more effective than SBIRT/Treatment as usual (TAU) as delivered in a primary care setting. While it is not f... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
08/28/2024
Locations: WMed Health Family Medicine, Kalamazoo, Michigan
Conditions: Substance-Related Disorders
Disrupting SDOH to Improve Substance Use and Mental Health Outcomes for Parents in Rural Regions
Recruiting
The study will evaluate the effectiveness of the Just Care for Families program in preventing Oregon Department of Human Services (ODHS)-involved parents in rural communities from escalating opioid and/or methamphetamine use and mental health disorders by disrupting the associated social determinants of health (SDOH). In addition, investigators will examine the impacts of SDOH on Just Care treatment and the associated costs from the perspective of provider clinics delivering Just Care. Just Care... Read More
Gender:
ALL
Ages:
All
Trial Updated:
08/14/2024
Locations: Chestnut Health Systems, Eugene, Oregon
Conditions: Social Determinants of Health, Substance-Related Disorders
First Face Training Evaluation in Tribal Communities
Recruiting
The goal of this study is to evaluate a culturally grounded training curriculum, First Face for Mental Health, in Tribal communities, using a waitlist controlled trial design. This curriculum will train Tribal community members in how to respond to youth and adults experiencing mental health crises and serve as a bridge between these individuals and the help they need. The main questions the study aims to answer are:
* Does the training increase mental health knowledge, capacity and ability to... Read More
Gender:
ALL
Ages:
14 years and above
Trial Updated:
08/13/2024
Locations: Kootenai Tribe of Idaho, Bonners Ferry, Idaho +8 locations
Conditions: Mental Health, Substance-Related Disorders
Transdermal Rotigotine as Adjunct to Behavioral Therapy for Cocaine Use Disorder
Recruiting
This is a randomized, double-blind, placebo-controlled phase 2b pilot clinical trial to determine whether non-ergoline D3/D2/D1 dopamine (DA) receptor agonist rotigotine (RTG), in combination with treatment as usual, including individual or group behavioral therapy can a) reduce cocaine use and also b) increase brain activity in frontocortical areas of the brain, and, as a reflection of that - improve top-down cognitive control in persons with cocaine use disorder (CocUD).
Rotigotine is a marke... Read More
Gender:
ALL
Ages:
Between 18 years and 55 years
Trial Updated:
07/30/2024
Locations: Virginia Commonwealth University, Richmond, Virginia
Conditions: Substance-Related Disorders
Maternal Brain Imaging in Opioid Use Disorder
Recruiting
This research study aims to learn more about opioid use disorder (OUD) during pregnancy and how outcomes for pregnant women and their newborns can be improved. During pregnancy, people with OUD are prescribed medication-assisted therapy (MAT). The investigators are interested to know how the medication is broken down by the body during pregnancy and how effective it is. The investigators also want to learn if this medication and OUD have any effect on the different parts of the brain when compar... Read More
Gender:
FEMALE
Ages:
Between 18 years and 100 years
Trial Updated:
05/16/2024
Locations: Riley Hospital for Children, Indianapolis, Indiana
Conditions: Opioid Use Disorder, Substance-Related Disorders, Substance Use, Pregnancy Related, Narcotic-Related Disorders, Buprenorphine Dependence
Expression of Stress Markers During Meth Treatment (EXPRESS+)
Recruiting
This is a non-randomized behavioral trial that aims to investigate whether changes in inflammatory and type I IFN expression coincide with changes in methamphetamine use and viral load over the course of 12 weeks in HIV-positive people assigned male at birth with and without methamphetamine use disorder.
Gender:
MALE
Ages:
Between 18 years and 45 years
Trial Updated:
05/06/2024
Locations: UCLA Vine Street Clinic, Los Angeles, California
Conditions: Substance-Related Disorders, HIV
Neuroimaging and CBD for Opiod Use Disorder
Recruiting
The investigators propose an imaging study to investigate the neurobiological effects of CBD (vs placebo) in participants with opioid use disorder who are maintained on methadone. The purpose of the study is to determine the neural circuits and transmitters associated with the effects of CBD on to reduce craving and anxiety. The neuroimaging will be conducted in participants immediately following their first administration of CBD (800mg or placebo) and one week after the last administration (3 d... Read More
Gender:
ALL
Ages:
Between 18 years and 65 years
Trial Updated:
09/25/2023
Locations: Icahn School of Medicine at Mount Sinai, New York, New York
Conditions: Heroin Abuse, Opioid Use Disorder, Substance-Related Disorders, Opioid-Related Disorders
Preventing Impaired Driving Among Adolescents
Recruiting
The primary goal of this project is to evaluate the efficacy of webCHAT, a single-session web-intervention, on reducing impaired driving among adolescents receiving behind-the-wheel training at driver education programs.
Gender:
ALL
Ages:
Between 15 years and 17 years
Trial Updated:
05/04/2023
Locations: DriveSafe Driving School, Denver, Colorado +1 locations
Conditions: Substance-Related Disorders
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