Systemic Lupus Erythematosus Clinical Trials

A listing of 50 Systemic Lupus Erythematosus clinical trials actively recruiting volunteers for paid trials and research studies in various therapeutic areas.

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There are currently 50 active clinical trials seeking participants for Systemic Lupus Erythematosus research studies. The states with the highest number of trials for Systemic Lupus Erythematosus participants are California, Florida, Texas and New York.

Featured Trial

Paid Clinical Studies Nationwide

Recruiting

Nationwide clinical trials offered in your area. Some trials offering up to several thousand dollars in compensation for participation.

Conditions:

Healthy

Healthy Volunteer Study

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* Compensation for time may be available

Featured Trial

Chronic Cough Study

Recruiting

Are you tired of living with chronic cough? The ASPIRE Study is now looking to enroll people from all backgrounds to help research potential new treatment options for chronic cough. You are under no obligation to take part and health insurance is not required. Find out more today! We’d love to hear from you.

Conditions:

Chronic Cough

Refractory or Unexplained Chronic Cough

Cough

Asthma

Allergic Asthma

Learn More

Featured Trial

Studying an Investigational Virus Vaccine

Recruiting

The main objectives of this study are to assess the safety and effectiveness of an investigational vaccine aimed at preventing norovirus, commonly known as the stomach flu. Participants will be randomly assigned to receive either the investigational vaccine or a placebo. Should you express interest, you will be contacted directly by the research site, which will provide further details and answer any questions you may have about study requirements, risks/benefits, and any compensation.

Conditions:

Healthy

Interested in vaccine studies

All Conditions

Preventative Trials

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Featured Trial

Lupus Research Study

Recruiting

Learn more about a research study for adults suffering from Lupus. Participants may also be eligible for reimbursement for some costs, such as travel or transportation. No health insurance is required to
participate in a study.

Conditions:

Systemic Lupus Erythematosus

Lupus

Lupus Erythematosus

Systemic

Systemic Lupus Erythematosus (SLE)

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A Study Describing the Efficacy and Safety of Belimumab Administered in Adult Participants With Early Systemic Lupus Erythematosus (SLE)

NCT06411249

Recruiting

This is a prospective, open-label, single arm 3-year clinical study to describe the short-term and long-term efficacy and safety of belimumab in participants with autoantibody positive early SLE with ongoing disease activity despite stable initial SLE therapy.

Gender:

ALL

Ages:

18 years and above

Trial Updated:

03/12/2025

Locations: GSK Investigational Site, Anniston, Alabama +42 locations

GSK Investigational Site, Anniston, Alabama

GSK Investigational Site, Flagstaff, Arizona

GSK Investigational Site, Mesa, Arizona

GSK Investigational Site, Covina, California

GSK Investigational Site, Fullerton, California

GSK Investigational Site, Los Angeles, California

GSK Investigational Site, Mission Hills, California

GSK Investigational Site, San Diego, California

GSK Investigational Site, Tujunga, California

GSK Investigational Site, Van Nuys, California

GSK Investigational Site, Aventura, Florida

GSK Investigational Site, Clearwater, Florida

GSK Investigational Site, Miami, Florida

GSK Investigational Site, Tamarac, Florida

GSK Investigational Site, Tampa, Florida

GSK Investigational Site, Atlanta, Georgia

GSK Investigational Site, Sugar Hill, Georgia

GSK Investigational Site, Morton Grove, Illinois

GSK Investigational Site, Lansing, Michigan

GSK Investigational Site, Charlotte, North Carolina

GSK Investigational Site, Duncansville, Pennsylvania

GSK Investigational Site, Austin, Texas

GSK Investigational Site, Baytown, Texas

GSK Investigational Site, Colleyville, Texas

GSK Investigational Site, Houston, Texas

GSK Investigational Site, Katy, Texas

GSK Investigational Site, Plano, Texas

GSK Investigational Site, Danville, Virginia

GSK Investigational Site, Glendale, Wisconsin

GSK Investigational Site, Berazategui, Not set

GSK Investigational Site, Ciudad Autonoma Buenos Aires, Not set

GSK Investigational Site, Ciudad Autonoma de Buenos Aires, Not set

GSK Investigational Site, Ciudad Autonoma de Buenos Aire, Not set

GSK Investigational Site, Mar del Plata, Not set

GSK Investigational Site, Santa Fe, Not set

GSK Investigational Site, Tucuman, Not set

GSK Investigational Site, Porto Alegre, Not set

GSK Investigational Site, Brescia, Not set

GSK Investigational Site, Rome, Not set

GSK Investigational Site, Osaka, Not set

GSK Investigational Site, Murcia, Not set

GSK Investigational Site, Valladolid, Not set

Conditions: Systemic Lupus Erythematosus

Learn More ›

Prospective Registry Investigating Maternal and Infant Outcomes in Anifrolumab Users

NCT06659029

Recruiting

PRIMULA Preg (Prospective Registry Investigating Maternal and Infant Outcomes in Anifrolumab Users) is a prospective, observational cohort study designed to evaluate the association between anifrolumab exposure during pregnancy and subsequent adverse maternal, fetal, and infant outcomes. This study will fulfil an FDA post-marketing requirement.

Gender:

FEMALE

Ages:

All

Trial Updated:

03/12/2025

Locations: Research Site, Las Vegas, Nevada

Conditions: Systemic Lupus Erythematosus

Learn More ›

A Study to Assess Effectiveness and Safety of Deucravacitinib Compared With Placebo in Participants With Active Systemic Lupus Erythematosus (SLE)

NCT05617677

Recruiting

The purpose of this study is to evaluate the effectiveness and safety of deucravacitinib compared with placebo in an active moderate to severe Systemic Lupus Erythematosus (SLE) population.

Gender:

ALL

Ages:

Between 18 years and 75 years

Trial Updated:

03/11/2025

Locations: University of Alabama at Birmingham, Birmingham, Alabama +209 locations

University of Alabama at Birmingham, Birmingham, Alabama

Local Institution - 0229, Phoenix, Arizona

Local Institution - 0230, Phoenix, Arizona

The University of Arizona Arthritis Center, Tucson, Arizona

Kaiser Permanente, Fontana, California

Private Practice - Dr. Chandrakant V. Mehta, Hemet, California

Arthritis & Osteoporosis Medical Center - La Palma, La Palma, California

UCLA Clinical & Translational Research Center (CTRC), Los Angeles, California

Private Practice - Dr. Hans Richard Barthel, Santa Barbara, California

Local Institution - 0099, Denver, Colorado

Yale New Haven Hospital-Smilow Cancer Center, New Haven, Connecticut

Rheumatology Assoc. Of South Florida, Boca Raton, Florida

Nouvelle Clinical Research, Cutler Bay, Florida

University of Florida College of Medicine, Gainesville, Florida

University of Miami Hospital and Clinics, Sylvester Cancer Center, Miami, Florida

Omega Research Group - Orlando, Orlando, Florida

West Broward Rheumatology Associates, Tamarac, Florida

Genesis Clinical Research, LLC, Tampa, Florida

Local Institution - 0165, Tampa, Florida

Piedmont West, Atlanta, Georgia

Local Institution - 0228, Lawrenceville, Georgia

Local Institution - 0234, Lawrenceville, Georgia

North Georgia Rheumatology, Lawrenceville, Georgia

Local Institution - 0227, Des Plaines, Illinois

Greater Chicago Specialty Physicians, Schaumburg, Illinois

Local Institution - 0108, Indianapolis, Indiana

Lake Cumberland Rheumatology, New Albany, Indiana

Ochsner Clinic Foundation, New Orleans, Louisiana

Local Institution - 0006, Detroit, Michigan

Saint Paul Rheumatology, Eagan, Minnesota

Atlantic Health System Overlook Medical Center, Summit, New Jersey

Local Institution - 0159, Bronx, New York

The Feinstein Institute for Medical Research, Manhasset, New York

NYU Langone Health, New York, New York

University of Rochester Medical Center, Rochester, New York

Carolinas HealthCare System SouthPark, Charlotte, North Carolina

Local Institution - 0003, Memphis, Tennessee

Arthritis and Rheumatology Research Institute, Allen, Texas

UT Southwestern Medical Center, Dallas, Texas

Local Institution - 0088, Fort Worth, Texas

Local Institution - 0219, Lubbock, Texas

Advanced Rheumatology of Houston - Woodlands, The Woodlands, Texas

Carilion Clinic, Roanoke, Virginia

Swedish Medical Center, Seattle, Washington

University of Washington Medical Center - Montlake, Seattle, Washington

Local Institution - 0063, Franklin, Wisconsin

Centro Médico Del Dr Javier Gerardo Tartaglione, Ciudad Autónoma de Buenos Aires, Buenos Aires

Instituto De Investigaciones Clinicas Quilmes, Quilmes, Buenos Aires

Fundacion Cidea, Buenos Aires, Ciudad Autónoma De Buenos Aires

APRILLUS Asistencia e Investigacion Clinica, Caba, Ciudad Autónoma De Buenos Aires

Investigaciones Clínicas Tucumán, San Miguel de Tucuman, Tucumán

Hospital Británico de Buenos Aires, Buenos Aires, Not set

Hospital J. M. Ramos Mejía, Ciudad Autónoma de Buenos Aires, Not set

Hospital Córdoba, Córdoba, Not set

Instituto de Reumatología, Mendoza, Not set

Local Institution - 0224, Salvador, Bahia

Hospital Brasilia, Lago sul, Distrito Federal

Santa Casa de Misericordia de Belo Horizonte, Belo Horizonte, Minas Gerais

Cmip-Centro Mineiro de Pesquisa, Juiz de Fora, Minas Gerais

Hospital Universitário Evangélico Mackenzie, Curitiba, Paraná

Local Institution - 0075, Niteroi, Rio De Janeiro

Hospital São Lucas da PUCRS, Porto Alegre, Rio Grande Do Sul

Clinica Medica Bonfiglioli, Campinas, São Paulo

Hospital das Clínicas da Faculdade de Medicina de Ribeirão Preto da Universidade de São Paulo (USP) - HCFMRP, Ribeirão Preto, São Paulo

Hospital do Rim e Hipertensão, Sao Paulo, São Paulo

Hospital de Base de São José do Rio Preto, São José do Rio Preto, São Paulo

Hospital Universitário Pedro Ernesto, Rio de Janeiro, Not set

Hospital das Clinicas FMUSP, São Paulo, Not set

Local Institution - 0048, São Paulo, Not set

Medical Center Artmed, Plovdiv, Not set

Local Institution - 0217, Sofia, Not set

ACIBADEM City Clinic Diagnostic-Consultative Center, Sofia, Not set

University of Calgary, Cumming School of Medicine, Calgary, Alberta

Local Institution - 0160, Hamilton, Ontario

St. Joseph's Health Care, London, Ontario

Toronto Western Hospital, Toronto, Ontario

Centre intégré de santé et de services sociaux du Bas Saint-Laurent- Hôpital régional de Rimouski, Rimouski, Quebec

The First Afflilated Hospital of Bengbu Medical College, Bengbu, Anhui

Beijing Peking Union Medical College Hospital, Beijing, Beijing

The First Affiliated hospital of Xiamen University, Xiamen, Fujian

Guangdong Provincial People's Hospital, Guangzhou, Guangdong

The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, Guangdong

Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou, Guangdong

ShenZhen People's Hospital, Shenzhen, Guangdong

Local Institution - 0153, Baoding, Hebei

The First Affiliated Hospital of Henan University of Science &Technology, Luoyang, Henan

The First Affiliated Hospital of Zhengzhou Universtiy, Zhengzhou, Henan

Union Hospital Tongji Medical College Huazhong University of Science and Technology, Wuhan, Hubei

Xiangya Hospital Central South University, Changsha, Hunan

ZhuZhou Central Hospital, Zhuzhou, Hunan

Local Institution - 0059, Baotou, Inner Mongolia

The Affiliated Hospital of Inner Mongolia Medical University, Hohhot, Inner Mongolia

The First People's Hospital of Changzhou, Changzhou, Jiangsu

Jiu Jiang No.1 People's Hospital, Jiujiang, Jiangxi

Local Institution - 0071, Nanchang, Jiangxi

The First Affiliated Hospital of Nanchang University, Nanchang, Jiangxi

The Second Affiliated Hospital of Nanchang University, Nanchang, Jiangxi

Jiangxi Pingxiang People's Hospital, Pingxiang, Jiangxi

The First Hospital of China Medical University, Shenyang, Liaoning

Shengjing Hospital of China Medical University, Shenyang, Liaoning

Local Institution - 0149, Jinan, Shandong

Ruijin Hospital Shanghai Jiaotong University School of Medicine, Shanghai, Shanghai

Huashan Hospital, Fudan University, Shanghai, Shanghai

West China Hospital, Sichuan University, Cheng Du, Sichuan

Local Institution - 0053, Tianjin, Tianjin

People's Hospital of Xinjiang Uygur Autonomous Region, Urumqi, Xinjiang

The first Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang

Wenzhou People's Hospital, Wenzhou, Zhejiang

Renji Hospital Shanghai Jiao Tong University School of Medicine, Shanghai, Not set

Shanxi Bethune Hospital, Taiyuan, Not set

Salud SURA Industriales, Medellín, Antioquia

Centro Integral de Reumatología del Caribe, Barranquilla, Atlántico

Servimed EU, Bucaramanga, Santander

Hospital Universitario San Ignacio, Bogota, Not set

Cireem Sas, Bogotá, Not set

IPS Centro Médico Julián Coronel S.A.S, Cali, Not set

Local Institution - 0058, Cali, Not set

Preventive Care, Chia, Not set

Local Institution - 0055, Medellin, Not set

Nouvel Hôpital Civil (NHC), Strasbourg, Alsace

Centre Hospitalier Universitaire de Nantes - L' Hopital l'hôtel-Dieu, Nantes, Loire-Atlantique

Hôpitaux Universitaires Paris Sud - Hôpital Bicêtre, Le Kremlin-Bicêtre, Not set

Centre Hospitalier Régional Universitaire de Tours - Hôpital Bretonneau, Tours, Not set

Universitaetsklinikum Tuebingen, Tübingen, Baden-Württemberg

Klinikum der Ludwig-Maximilians-Universitaet Muenchen, Muenchen, Bayern

Universitaetsklinikum Carl Gustav Carus Dresden, Dresden, Sachsen

Universitätsklinikum Schleswig-Holstein, Lübeck, Schleswig-Holstein

DRK-Krankenhaus Rabenstein, Chemnitz, Not set

Universitaetsklinikum Erlangen, Erlangen, Not set

Universitaetsklinikum Koeln, Köln, Not set

Klinische Forschung im medizinischen Versorgungalltag GbR, Planegg, Not set

Tuen Mun Hospital, Tuen Mun, Not set

Local Institution - 0213, Vizianagaram, Andhra Pradesh

Amber Clinic, Ahmedabad, Gujarat

Medanta The Medicity, Gurugram, Haryana

ChanRe Rheumatology And Immunology Center And Research, Bengaluru, Karnataka

Local Institution - 0222, Hyderabad, Telangana

Nizam's Institute of Medical Sciences, Hyderabad, Telangana

Local Institution - 0119, Manorhamilton, Leitrim

Local Institution - 0130, Cork, Not set

Local Institution - 0157, Dublin, Not set

Local Institution - 0172, Dublin, Not set

AOU Policlinico Umberto I, Roma, Lazio

Centro Specialistico Ortopedico Traumatologico Gaetano Pini - CTO, Milano, Lombardia

Azienda Ospedaliera Universitaria Pisana, Pisa, Toscana

Azienda Ospedale - Università Padova, Padova, Veneto

Azienda Ospedaliera Spedali Civili di Brescia, Brescia, Not set

Local Institution - 0072, Milano, Not set

AOU della Campania Luigi Vanvitelli, Napoli, Not set

Local Institution - 0118, Pavia, Not set

Azienda Ospedaliera Universitaria Integrata Verona - Ospedale Borgo Roma, Verona, Not set

Local Institution - 0102, Gwangju-si, Kwangju-Kwangyǒkshi

Ajou University Hospital, Suwon, Kyǒnggi-do

The Catholic Univ. of Korea Seoul St. Mary's Hospital, Seoul, Seoul-teukbyeolsi [Seoul]

Local Institution - 0105, Jung-gu, Taegu-Kwangyǒkshi

Local Institution - 0106, Jung-gu, Taejǒn-Kwangyǒkshi

Hanyang University Seoul Hospital, Seoul, Not set

Hospital of Lithuanian University of Health Sciences Kauno klinikos, Kaunas, Kauno Apskritis

Centro Medico del Angel, Mexicali, Baja California

Boca Clinical Trials Mexico SC, Ciudad de México, Distrito Federal

Local Institution - 0027, Mexico City, Distrito Federal

Instituto para el DeSarrollo Integral de la Salud S de RL de CV, Mexico City, Distrito Federal

Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran, Mexico City, Distrito Federal

Clinstile, S.A. de C.V., Mexico, Distrito Federal

Hospital Aranda de La Parra, Leon, Guanajuato

Local Institution - 0024, Zapopan, Jalisco

Investigacion y Biomedicina de Chihuahua, Chihuahua, Not set

Local Institution - 0014, Mexico City, Not set

Boca Clinical Trials Mexico SC, Puebla, Not set

Local Institution - 0237, Chisinau, Chișinău

Local Institution - 0238, Chisinau, Chișinău

Local Institution - 0236, Chisinau, Not set

Hogar Clínica San Juan de Dios, Arequipa, Not set

Instituto Peruano del Hueso y la Articulación, Lima, Not set

Centro Medico CORPAC, Lima, Not set

Investigaciones Clínicas / Instituto de Ginecología y Reproducción, Lima, Not set

Local Institution - 0196, Wroclaw, Dolnośląskie

Szpital Uniwersytecki Nr 2 im. dr J. Biziela w Bydgoszczy, Bydgoszcz, Kujawsko-pomorskie

Mak-Med Clinic Sp. Z O.O., Nadarzyn, Mazowieckie

Narodowy Instytut Geriatrii, Reumatologii i Rehabilitacji, Warsaw, Mazowieckie

Rheuma Medicus Sp. z o.o., Warszawa, Mazowieckie

Local Institution - 0194, Wolomin, Mazowieckie

Centrum Medyczne Plejady, Krakow, Małopolskie

Medyczne Centrum Hetmańska, Poznan, Wielkopolskie

Local Institution - 0030, Poznań, Wielkopolskie

Nova Reuma Społka Partnerska, Bialystok, Not set

Synexus Polska Sp. z o.o. Oddzial w Poznaniu, Poznan, Not set

Local Institution - 0211, Belchatow, Łódzkie

Centrum Medyczne Pratia Katowice, Katowice, Śląskie

Local Institution - 0073, Lisbon, Not set

Centro Reumatologico Caguas, Caguas, Not set

GCM Medical Group, PSC - Hato Rey Site, San Juan, Not set

Hiperdia Piața Sudului, Bucharest, Bucureşti

Hightech Medical Services SRL-Centrul pentru Studiul Metabolismului, Bucharest, București

Spital Clinic Sf. Maria, Bucharest, București

Delta Health Care, Bucharest, București

Spitalul Clinic Colentina, Bucuresti, București

CCBR Clinical Research, Bucuresti, București

Medisof Diagnostic SR, Craiova, Dolj

RK Medcenter, Iasi, Iași

Sc Medaudio-Optica Srl, Râmnicu Vâlcea, Vâlcea

Private Practice - Dr. Carina Anna Triff, Timisoara, Not set

Local Institution - 0207, Svidnik, Prešovský Kraj

Local Institution - 0206, Martin, Žilinský Kraj

Local Institution - 0232, Pretoria, Gauteng

Local Institution - 0233, Cape Town, Western Cape

Local Institution - 0231, Stellenbosch, Western Cape

Gazi University Health Research and Application Center Gazi Hospital, Ankara, Not set

Istanbul University Cerrahpasa Medical School Internal Diseases Institute, Istanbul, Not set

Kocaeli Üniversitesi, Kocaeli, Not set

Conditions: Systemic Lupus Erythematosus

Learn More ›

The Role of Anifrolumab in Improving Markers of Vascular Risk in Patients With Systemic Lupus Erythematosus (SLE) - IFN-CVD

NCT05440422

Recruiting

Background: People with systemic lupus erythematosus (SLE) are at risk of developing complications in their blood vessels. This can increase the risk of heart attacks or stroke. No medications have been effective at reducing this risk in people with lupus. Objective: To test whether a drug (anifrolumab) can improve blood vessel function and reduce blood vessel inflammation in people with SLE. Eligibility: People aged 18 to 80 years with SLE. Design: Participants will undergo screening. Th... Read More

Gender:

ALL

Ages:

Between 18 years and 80 years

Trial Updated:

03/10/2025

Locations: National Institutes of Health Clinical Center, Bethesda, Maryland

Conditions: Systemic Lupus Erythematosus, Cardiovascular Disease, Premature Atherosclerosis

Learn More ›

A Study Evaluating the Efficacy and Safety of Afimetoran Compared With Placebo in Participants With Active Systemic Lupus Erythematosus (SLE)

NCT04895696

Recruiting

The purpose of this study is to evaluate the effectiveness, safety and tolerability of Afimetoran in participants with active Systemic Lupus Erythematosus (SLE). The extension period will provide additional long-term safety and efficacy data and enable those participants initially randomized to placebo to receive treatment with Afimetoran.

Gender:

ALL

Ages:

Between 18 years and 70 years

Trial Updated:

03/05/2025

Locations: Local Institution - 0100, Birmingham, Alabama +173 locations

Local Institution - 0100, Birmingham, Alabama

St Joseph Heritage Healthcare-Rheumatology, Fullerton, California

Christine Thai, MD, Huntington Beach, California

UCSD - Altman Clinical and Translational Research Institute (ACTRI), La Jolla, California

Advanced Medical Research - La Palma, La Palma, California

Local Institution - 0202, Los Angeles, California

Rheumatology Center of San Diego, San Diego, California

Private Practice - Dr. Nazanin Firooz, West Hills, California

Local Institution - 0164, Woodland Hills, California

Colorado Arthritis Associates, Denver, Colorado

UConn Health, Farmington, Connecticut

Bay Area Arthritis and Osteoporosis, Brandon, Florida

Clinical Research of West Florida, Inc. (Clearwater), Clearwater, Florida

University Of Florida, Gainesville, Florida

Vida Clinical Research, Kissimmee, Florida

Omega Research MetroWest, Orlando, Florida

Millennium Research, Ormond Beach, Florida

IRIS Research and Development, LLC, Plantation, Florida

Local Institution - 0137, South Miami, Florida

West Broward Rheumatology Associates, Tamarac, Florida

Piedmont West, Atlanta, Georgia

Private Practice - Dr. Jefrey Lieberman, Decatur, Georgia

North Georgia Rheumatology, Suwanee, Georgia

Greater Chicago Specialty Physicians - Orland Park, Orland Park, Illinois

Western KY Rheumatology, Hopkinsville, Kentucky

Local Institution - 0171, Baton Rouge, Louisiana

Local Institution - 0134, Wheaton, Maryland

Local Institution - 0221, Rochester Hills, Michigan

Saint Paul Rheumatology, Eagan, Minnesota

Washington University/ Barnes Jewish Hospital, Saint Louis, Missouri

Local Institution - 0165, Saint Louis, Missouri

Local Institution - 0091, Las Vegas, Nevada

Sahni Rheumatology & Therapy, West Long Branch, New Jersey

Local Institution - 0132, Bronx, New York

The Feinstein Institute for Medical Research, Manhasset, New York

Local Institution - 0203, Charlotte, North Carolina

DJL Clinical Research, PLLC, Charlotte, North Carolina

The Ohio State University Wexner Medical Center (OSUWMC) - CarePoint East-Rheumatology and Immunolog, Columbus, Ohio

Paramount Medical Research and Consulting, Llc, Middleburg Heights, Ohio

Oklahoma Medical Research Foundation-Multiple Sclerosis Center of Excellence, Oklahoma City, Oklahoma

Oklahoma Medical Research Foundation, Oklahoma City, Oklahoma

Shelby Research LLC, Memphis, Tennessee

Arthritis and Rheumatology Research Institute, Allen, Texas

Local Institution - 0152, Allen, Texas

Amarillo Center for Clinical Research-Research, Amarillo, Texas

Local Institution - 0029, Mesquite, Texas

Sun Research Institute, San Antonio, Texas

Overlake Arthritis and Osteoporosis Center, Bellevue, Washington

Local Institution - 0130, Quilmes, Buenos Aires

Local Institution - 0195, San Fernando, Buenos Aires

Local Institution - 0024, San Isidro, Buenos Aires

Local Institution - 0025, Córdoba, Cordoba

Local Institution - 0074, Buenos Aires, Distrito Federal

Local Institution - 0145, Caba, Distrito Federal

Local Institution - 0040, Caba, Distrito Federal

Local Institution - 0027, San Miguel de Tucumán, Tucuman

Local Institution - 0207, Buenos Aires, Not set

Local Institution - 0128, Buenos Aires, Not set

Local Institution - 0041, San Juan, Not set

Local Institution - 0063, Botany, New South Wales

Local Institution - 0072, Westmead, New South Wales

Local Institution - 0066, Maroochydore, Queensland

Local Institution - 0065, Woodville, South Australia

Local Institution - 0062, Camberwell, Victoria

Local Institution - 0064, Ivanhoe, Victoria

Serviços Especializados em Reumatologia, Salvador, Bahia

Centro de Pesquisas da Clínica IBIS, Salvador, Bahia

IPC-MT Instituto de Pesquisas Clínicas de Mato Grosso, Cuiabá, Mato Grosso

Cmip-Centro Mineiro de Pesquisa, Juiz de Fora, Minas Gerais

Centro de Estudos em Terapias Inovadoras-Rheumatology, Curitiba, Parana

LMK Serviços Médicos S/S-Reumacenter, Porto Alegre, RIO Grande DO SUL

Centro Multidisciplinar de Estudos Clinicos, São Bernardo do Campo, SAO Paulo

Hospital de Base de São José do Rio Preto-CIP - Centro Integrado de Pesquisas, São José do Rio Preto, SAO Paulo

Local Institution - 0013, São Paulo, SAO Paulo

CEPIC - Centro Paulista de Investigação Clínica, São Paulo, Not set

Local Institution - 0127, Osorno, LOS Lagos

Local Institution - 0143, Valdivia, Los Rios

Local Institution - 0073, Santiago, Metropolitana

Local Institution - 0043, Santiago, Metropolitana

Local Institution - 0075, Santiago, Región Metropolitana De Santiago

Local Institution - 0177, Beijing, Beijing

Peking University Shougang Hospital, Beijing, Beijing

The Seventh Affiliated Hospital, Sun Yat-sen University, Shenzhen, Guangdong

Local Institution - 0196, Baoding, Hebei

Nanjing Drum Tower Hospital The Affiliated Hospital of Nanjing University Medical School, Nanjing, Jiangsu

Jiangsu Province Hospital, Nanjing, Jiangsu

The First Affiliated Hospital of Soochow University, Suzhou, Jiangsu

The First Hospital of Jilin University, Changchun, Jilin

The 2nd Affiliated Hospital of Dalian Medical University, Dalian, Liaoning

Qilu Hospital of Shandong University (Qingdao), Jinan, Shandong

Jining No.1 People's Hospital, Jining, Shandong

Local Institution - 0194, Changzhi, Shanxi

Local Institution - 0181, Kunming, Yunnan

Local Institution - 0191, Beijing, Not set

Salud SURA Industriales, Medellín, Antioquia

Local Institution - 0185, Cali, Valle Del Cauca

Centro de Reumatologia y Ortopedia, Barranquilla, Not set

Centro de Investigacion en Reumatologia y Especialidades Medicas S.A.S, Bogotá, Not set

Centro de Estudios de Reumatología y Dermatología SAS, Cali, Not set

Preventive Care, Chía, Not set

Healthy Medical Center S.A.S, Zipaquira, Not set

CHU Bordeaux Haut-Leveque, Pessac, Aquitaine

CHRU de Brest, Brest, Finistère

Bordeaux University Hospital - Pellegrin-Rhumatologie, Bordeaux, Not set

Centre Hospitalier Universitaire de Caen Normandie, Caen, Not set

Chru De Lille, Lille Cedex, Not set

Hôpital Européen Marseille-Service de recherche clinique, Marseille, Not set

CHU Strasbourg-Hautepierre-Service de Rhumatologie, Strasbourg, Not set

Local Institution - 0087, Köln, Nordrhein-Westfalen

Charité Research Organisation, Berlin, Not set

Local Institution - 0086, Essen, Not set

Klinikum Der Albrecht-Ludwigs-Universitat, Freiburg, Not set

All India Institute of Medical Sciences, New Delhi, Delhi

Local Institution - 0226, Ahmedabad, Gujarat

Medanta The Medicity, Gurugram, Haryana

ChanRe Rheumatology And Immunology Center And Research, Bengaluru, Karnataka

Krishna Institute of Medical Science, Secunderabad, Telangana

Local Institution - 0119, Manorhamilton, Leitrim

Local Institution - 0106, Dublin, Not set

Local Institution - 0107, Galway, Not set

Local Institution - 0114, Eiheiji-cho,Yoshida-gun, Fukui

University of Occupational and Enviromental Health, Kitakyushu, Fukuoka

Hokkaido University Hospital, Sapporo, Hokkaido

Kanazawa University Hospital, Kanazawa, Ishikawa

Tohoku University Hospital-Department of Rheumatology, Sendai-shi, Miyagi

Juntendo University Hospital, Bunkyo-ku, Tokyo

Tokyo Metropolitan Tama Medical Center, Fuchu, Tokyo

Nihon University Itabashi Hospital, Itabashiku, Tokyo

Local Institution - 0150, Meguro-ku, Tokyo

Keio university hospital-Division of Rheumatology, Department of Internal Medicine, Shinjuku-ku, Tokyo

National Center for Global Health and Medicine, Shinjuku-ku, Tokyo

Koujunkai Daido Clinic, Aichi, Not set

National Hospital Organization Chiba-East Hospital, Chiba, Not set

Local Institution - 0162, Fukushima, Not set

St. Luke's International Hospital, Tokyo, Not set

Local Institution - 0116, Tokyo, Not set

Local Institution - 0060, Mexico City, Distrito Federal

Local Institution - 0018, Mexico City, Distrito Federal

Local Institution - 0182, Mexico City, Distrito Federal

Local Institution - 0020, Leon, Guanajuato

Local Institution - 0017, Guadalajara, Jalisco

Local Institution - 0022, Zapopan, Jalisco

Local Institution - 0071, Monterrey, Nuevo LEON

Local Institution - 0021, Chihuahua, Not set

Local Institution - 0061, Merida, Not set

Local Institution - 0158, Mexico City, Not set

Centrum Medyczne Reuma Park, Warszawa, Mazowieckie

Local Institution - 0161, Łomża, Podlaskie

Local Institution - 0051, Bydgoszcz, Not set

Medyczne Centrum Hetmańska, Poznan, Not set

Local Institution - 0142, Rzeszów, Not set

Local Institution - 0050, Sosnowiec, Not set

MICS Centrum Medyczne Warszawa, Warszawa, Not set

Uniwersytecki Szpital Kliniczny-Klinika Reumatologii i Chorób Wewnętrznych, Wrocław, Not set

GCM Medical Group, PSC - Hato Rey Site-Hato Rey, San Juan, Not set

Local Institution - 0131, San Juan, Not set

Sc Medaudio-Optica Srl, Râmnicu Vâlcea, Vâlcea

Hightech Medical Services SRL-Centrul pentru Studiul Metabolismului, Bucharest, Not set

Spital Clinic Sf. Maria, Bucharest, Not set

Centrul de Kinetoterapie si Masaj Banat SRL, Giroc, Not set

Local Institution - 0206, Santander, Cantabria

CHUAC-Complejo Hospitalario Universitario A Coruña-Reumatologia, A Coruña, Not set

Hospital Universitari Vall d'Hebron-Rheumatology, Barcelona, Not set

HOSPITAL GENERAL UNIVERSITARIO GREGORIO MARAÑON-Reumatología, Madrid, Not set

Hospital Universitario Virgen de Valme-RHEUMATOLOGY, Sevilla, Not set

Chang Gung Memorial Hospital at Kaohsiung-Rheumatology, Kaohsiung Niao Sung Dist, Not set

China Medical University Hospital, Taichung, Not set

Taichung Veterans General Hospital, Taichung, Not set

National Taiwan University Hospital-Immunology, Taipei, Not set

Taipei Veterans General Hospital, Taipei, Not set

Addenbrooke's Hospital, Cambridge, Cambridgeshire

Local Institution - 0110, Bradford, Not set

Local Institution - 0120, Edinburgh, Not set

Local Institution - 0125, Manchester, Not set

Conditions: Systemic Lupus Erythematosus

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Phase 3 Study to Evaluate Two Regimens of Ianalumab on Top of Standard-of-care Therapy in Patients With Systemic Lupus Erythematosus (SIRIUS-SLE 1)

NCT05639114

Recruiting

The trial will evaluate efficacy, safety and tolerability of two regimens of ianalumab compared to placebo, given as monthly or quarterly subcutaneous (s.c.) injection on top of standard-of-care (SoC) treatment in participants with active systemic lupus erythematosus (SLE).

Gender:

ALL

Ages:

Between 12 years and 100 years

Trial Updated:

03/05/2025

Locations: Providence Medical Center, Burbank, California +157 locations

Providence Medical Center, Burbank, California

University of California San Diego, La Jolla, California

Keck School of Medicine, Los Angeles, California

Millennium Clinical Trials, Westlake Village, California

University of Colorado, Aurora, Colorado

Yale University School Of Medicine, New Haven, Connecticut

Clinical Res Of W Florida, Clearwater, Florida

GNP Research, Hollywood, Florida

University Of Miami, Miami, Florida

Clinical Research of West Florida Inc, Tampa, Florida

Parris and Associates Rheumatology, Lawrenceville, Georgia

Robert A Hozman MD SC, Skokie, Illinois

Lake Cumberland Rheumatology and In, New Albany, Indiana

Ochsner Clinic Foundation, Baton Rouge, Louisiana

Henry Ford Health, Detroit, Michigan

Univ of Nevada School of Med, Las Vegas, Nevada

Innovative Health Research, Las Vegas, Nevada

Sahni Rheumatology and Therapy, West Long Branch, New Jersey

NYU Langone Health, Brooklyn, New York

Medical Center Main Campus, Cleveland, Ohio

STAT Research Inc, Dayton, Ohio

Paramount Med Rsrch and Consult LLC, Middleburg Heights, Ohio

Prisma Health, Columbia, South Carolina

Shelby Research LLC, Memphis, Tennessee

Accurate Clinical Research Research, Baytown, Texas

Texas Arthritis Center, El Paso, Texas

Epic Medical Research, Red Oak, Texas

Novartis Investigative Site, Salvador, BA

Novartis Investigative Site, Brasilia, DF

Novartis Investigative Site, Vitoria, ES

Novartis Investigative Site, Belo Horizonte, MG

Novartis Investigative Site, Curitiba, PR

Novartis Investigative Site, Niteroi, RJ

Novartis Investigative Site, Rio de Janeiro, RJ

Novartis Investigative Site, Barretos, Sao Paulo

Novartis Investigative Site, Sao Paulo, SP

Novartis Investigative Site, Salvador, Not set

Novartis Investigative Site, Plovdiv, Not set

Novartis Investigative Site, Ruse, Not set

Novartis Investigative Site, Sofia, Not set

Novartis Investigative Site, Calgary, Alberta

Novartis Investigative Site, Vancouver, British Columbia

Novartis Investigative Site, Hamilton, Ontario

Novartis Investigative Site, Toronto, Ontario

Novartis Investigative Site, Rimouski, Quebec

Novartis Investigative Site, Guangzhou, Guangdong

Novartis Investigative Site, Shantou, Guangdong

Novartis Investigative Site, Haikou, Hainan

Novartis Investigative Site, Zhuzhou, Hunan

Novartis Investigative Site, Baotou, Inner Mongolia

Novartis Investigative Site, Nanjing, Jiangsu

Novartis Investigative Site, Suzhou, Jiangsu

Novartis Investigative Site, Nanchang, Jiangxi

Novartis Investigative Site, Pingxiang, Jiangxi

Novartis Investigative Site, Chang Chun, Jilin

Novartis Investigative Site, Linyi, Shandong

Novartis Investigative Site, Chengdu, Sichuan

Novartis Investigative Site, Urumqi, Xinjiang

Novartis Investigative Site, Wenzhou, Zhejiang

Novartis Investigative Site, Beijing, Not set

Novartis Investigative Site, Shanghai, Not set

Novartis Investigative Site, Wuhan, Not set

Novartis Investigative Site, Xinxiang, Not set

Novartis Investigative Site, Zhejiang, Not set

Novartis Investigative Site, Brno, Not set

Novartis Investigative Site, Praha 2, Not set

Novartis Investigative Site, Uherske Hradiste, Not set

Novartis Investigative Site, Guatemala City, Not set

Novartis Investigative Site, Guatemala, Not set

Novartis Investigative Site, Szekesfehervar, Fejer

Novartis Investigative Site, Budapest, Not set

Novartis Investigative Site, Gyula, Not set

Novartis Investigative Site, Haifa, Not set

Novartis Investigative Site, Ramat Gan, Not set

Novartis Investigative Site, Nagoya, Aichi

Novartis Investigative Site, Ichikawa, Chiba

Novartis Investigative Site, Fukuoka city, Fukuoka

Novartis Investigative Site, Kitakyushu, Fukuoka

Novartis Investigative Site, Sapporo city, Hokkaido

Novartis Investigative Site, Ono, Hyogo

Novartis Investigative Site, Kawasaki, Kanagawa

Novartis Investigative Site, Yokohama-city, Kanagawa

Novartis Investigative Site, Yokohama, Kanagawa

Novartis Investigative Site, Sendai city, Miyagi

Novartis Investigative Site, Kurashiki, Okayama

Novartis Investigative Site, Suita, Osaka

Novartis Investigative Site, Iruma-gun, Saitama

Novartis Investigative Site, Bunkyo ku, Tokyo

Novartis Investigative Site, Bunkyo-ku, Tokyo

Novartis Investigative Site, Chuo ku, Tokyo

Novartis Investigative Site, Fuchu-city, Tokyo

Novartis Investigative Site, Fuchu, Tokyo

Novartis Investigative Site, Itabashi-ku, Tokyo

Novartis Investigative Site, Meguro, Tokyo

Novartis Investigative Site, Shinjuku-ku, Tokyo

Novartis Investigative Site, Chiba, Not set

Novartis Investigative Site, Fukuoka, Not set

Novartis Investigative Site, Gifu, Not set

Novartis Investigative Site, Miyazaki, Not set

Novartis Investigative Site, Osaka, Not set

Novartis Investigative Site, Wroclaw, Dolnoslaskie

Novartis Investigative Site, Bydgoszcz, Not set

Novartis Investigative Site, Bytom, Not set

Novartis Investigative Site, Lodz, Not set

Novartis Investigative Site, Rzeszow, Not set

Novartis Investigative Site, Warszawa, Not set

Novartis Investigative Site, Braga, Not set

Novartis Investigative Site, Leiria, Not set

Novartis Investigative Site, Lisboa, Not set

Novartis Investigative Site, Singapore, Not set

Novartis Investigative Site, Bratislava, Not set

Novartis Investigative Site, Kosice, Not set

Novartis Investigative Site, Piestany, Not set

Novartis Investigative Site, Cape Town, Not set

Novartis Investigative Site, Panorama, Not set

Novartis Investigative Site, Pretoria, Not set

Novartis Investigative Site, Stellenbosch, Not set

Novartis Investigative Site, Umhlanga, Not set

Novartis Investigative Site, Elche, Alicante

Novartis Investigative Site, Santander, Cantabria

Novartis Investigative Site, Valladolid, Castilla Y Leon

Novartis Investigative Site, Badalona, Catalunya

Novartis Investigative Site, Barcelona, Catalunya

Novartis Investigative Site, Valencia, Comunidad Valenciana

Novartis Investigative Site, Badajoz, Extremadura

Novartis Investigative Site, Merida, Extremadura

Novartis Investigative Site, Santiago De Compostela, Galicia

Novartis Investigative Site, San Sebastian de los Reyes, Madrid

Novartis Investigative Site, El Palmar, Murcia

Novartis Investigative Site, Pamplona, Navarra

Novartis Investigative Site, Vitoria Gasteiz, Pais Vasco

Novartis Investigative Site, Vigo, Pontevedra

Novartis Investigative Site, La Laguna, Santa Cruz De Tenerife

Novartis Investigative Site, Madrid, Not set

Novartis Investigative Site, Songkhla, Hat Yai

Novartis Investigative Site, Bangkok, Not set

Novartis Investigative Site, Chiang Mai, Not set

Novartis Investigative Site, Ankara, Not set

Novartis Investigative Site, Aydin, Not set

Novartis Investigative Site, Etlik Ankara, Not set

Novartis Investigative Site, Izmir, Not set

Novartis Investigative Site, Konya, Not set

Conditions: Systemic Lupus Erythematosus

Learn More ›

Phase 3 Extension Study to Evaluate Long-term Safety of Ianalumab in Participants With Systemic Lupus Erythematosus (SIRIUS-SLE Extension).

NCT06133972

Recruiting

The purpose of this study is to evaluate long-term safety and tolerability of ianalumab in participants with systemic lupus erythematosus who have previously completed the treatment period in one of the two SIRIUS-SLE core studies (CVAY736F12301 or CVAY736F12302).

Gender:

ALL

Ages:

Between 12 years and 100 years

Trial Updated:

03/05/2025

Locations: Pinnacle Research Group Llc, Anniston, Alabama +48 locations

Pinnacle Research Group Llc, Anniston, Alabama

Advanced Medical Research, La Palma, California

Millennium Clinical Trials, Westlake Village, California

Clinical Res Of W Florida, Clearwater, Florida

Accurate Clinical Research, Lake Charles, Louisiana

Ahmed Arif Medical Research Center, Grand Blanc, Michigan

West Tennessee Research Institute, Jackson, Tennessee

Shelby Research LLC, Memphis, Tennessee

Novel Research LLC, Bellaire, Texas

Novartis Investigative Site, San Miguel de Tucuman, Tucuman

Novartis Investigative Site, Tucuman, Not set

Novartis Investigative Site, Maroochydore, Queensland

Novartis Investigative Site, Plovdiv, Not set

Novartis Investigative Site, Rimouski, Quebec

Novartis Investigative Site, Guangzhou, Guangdong

Novartis Investigative Site, Nanchang, Jiangxi

Novartis Investigative Site, Pingxiang, Jiangxi

Novartis Investigative Site, Chang Chun, Jilin

Novartis Investigative Site, Linyi, Shandong

Novartis Investigative Site, Urumqi, Xinjiang

Novartis Investigative Site, Zhejiang, Not set

Novartis Investigative Site, Brno, Not set

Novartis Investigative Site, Montpellier 5, Not set

Novartis Investigative Site, Paris, Not set

Novartis Investigative Site, Leipzig, Not set

Novartis Investigative Site, Guatemala City, Not set

Novartis Investigative Site, Guatemala, Not set

Novartis Investigative Site, Szekesfehervar, Fejer

Novartis Investigative Site, Nagoya, Aichi

Novartis Investigative Site, Sapporo city, Hokkaido

Novartis Investigative Site, Ipoh, Perak

Novartis Investigative Site, Wroclaw, Dolnoslaskie

Novartis Investigative Site, Bydgoszcz, Not set

Novartis Investigative Site, Bytom, Not set

Novartis Investigative Site, Warszawa, Not set

Novartis Investigative Site, Braga, Not set

Novartis Investigative Site, Brasov, Not set

Novartis Investigative Site, Cluj Napoca, Not set

Novartis Investigative Site, Santander, Cantabria

Novartis Investigative Site, Badalona, Catalunya

Novartis Investigative Site, Barcelona, Catalunya

Novartis Investigative Site, Santiago De Compostela, Galicia

Novartis Investigative Site, Madrid, Not set

Novartis Investigative Site, Taichung, Not set

Novartis Investigative Site, Bangkok, Not set

Conditions: Systemic Lupus Erythematosus

Learn More ›

UC-MSC Cell Therapy Study for SLE Patients

NCT06737380

Recruiting

The goal of this clinical trial is to evaluate the safety and effectiveness of UC-MSCs in adults with systemic lupus erythematosus (SLE). The main questions this study aims to answer are: 1. Can UC-MSCs improve kidney function and reduce SLE disease activity? 2. Are UC-MSCs safe and well-tolerated in this patient population? Participants in this study will: * Receive UC-MSCs in a single dose in addition to standard of care treatment. * Provide blood and urine samples for laboratory assessmen... Read More

Gender:

ALL

Ages:

Between 18 years and 75 years

Trial Updated:

03/05/2025

Locations: Medical University of South Carolina, Charleston, South Carolina

Conditions: SLE, Lupus, Systemic Lupus Erthematosus, Systemic Lupus Erythematosus, Systemic Lupus Erythematosus (SLE)

Learn More ›

Autologous Stem Cell Transplant (ASCT) for Autoimmune Diseases

NCT05029336

Recruiting

A subset of autoimmune diseases (ADs) in children and young adults are life-threatening and unresponsive to conventional treatments. In these patients, the delivery of high dose immunosuppressive therapy followed by autologous stem cell transplant (ASCT) offers a treatment strategy capable of purging the pathogenic, autoreactive immune system and an opportunity for "immune reset." This strategy has been used in adults across a myriad of indications with evidence for efficacy. This study proposes... Read More

Gender:

ALL

Ages:

Between 8 years and 25 years

Trial Updated:

03/04/2025

Locations: Children's Hospital of Philadelphia, Philadelphia, Pennsylvania

Conditions: Systemic Lupus Erythematosus, Systemic Sclerosis

Learn More ›

An Efficacy and Safety Study of Intravenous Anifrolumab to Treat Systemic Lupus Erythematosus in Pediatric Participants

NCT05835310

Recruiting

A Study to evaluate the PK, PD, efficacy, and safety of Anifrolumab in children with moderate to severe active SLE

Gender:

ALL

Ages:

Between 5 years and 17 years

Trial Updated:

03/04/2025

Locations: Research Site, Phoenix, Arizona +91 locations

Research Site, Phoenix, Arizona

Research Site, Los Angeles, California

Research Site, Washington, District of Columbia

Research Site, Chicago, Illinois

Research Site, Bethesda, Maryland

Research Site, Saint Paul, Minnesota

Research Site, Bronx, New York

Research Site, New Hyde Park, New York

Research Site, New York, New York

Research Site, Valhalla, New York

Research Site, Durham, North Carolina

Research Site, Cincinnati, Ohio

Research Site, Cleveland, Ohio

Research Site, Columbus, Ohio

Research Site, Portland, Oregon

Research Site, Philadelphia, Pennsylvania

Research Site, Greenville, South Carolina

Research Site, El Paso, Texas

Research Site, Houston, Texas

Research Site, Salt Lake City, Utah

Research Site, Buenos Aires, Not set

Research Site, Córdoba, Not set

Research Site, Rosario, Not set

Research Site, Botucatu, Not set

Research Site, Curitiba, Not set

Research Site, Porto Alegre, Not set

Research Site, Ribeirão Preto, Not set

Research Site, Sao Paulo, Not set

Research Site, Vancouver, British Columbia

Research Site, Toronto, Ontario

Research Site, Beijing, Not set

Research Site, Changchun, Not set

Research Site, Changsha, Not set

Research Site, Shanghai, Not set

Research Site, Suzhou, Not set

Research Site, Wenzhou, Not set

Research Site, Zhengzhou, Not set

Research Site, Barranquilla, Not set

Research Site, Medellin, Not set

Research Site, Bordeaux, Not set

Research Site, Bron, Not set

Research Site, Le Kremlin-Bicêtre, Not set

Research Site, LILLE Cedex, Not set

Research Site, Toulouse, Not set

Research Site, Berlin, Not set

Research Site, Freiburg, Not set

Research Site, Sankt Augustin, Not set

Research Site, Genova, Not set

Research Site, Milano, Not set

Research Site, Padova, Not set

Research Site, Roma, Not set

Research Site, Bunkyo-ku, Not set

Research Site, Chiba, Not set

Research Site, Fuchu-shi, Not set

Research Site, Kawasaki-shi, Not set

Research Site, Kobe-shi, Not set

Research Site, Obu-shi, Not set

Research Site, Shinjuku-ku, Not set

Research Site, Yokohama-shi, Not set

Research Site, Guadalajara, Not set

Research Site, Merida, Not set

Research Site, Mexico, Not set

Research Site, Monterrey, Not set

Research Site, Toluca, Not set

Research Site, Lodź, Not set

Research Site, Warszawa, Not set

Research Site, Wroclaw, Not set

Research Site, Lisboa, Not set

Research Site, Porto, Not set

Research Site, Cape Town, Not set

Research Site, Esplugues de Llobregat, Not set

Research Site, Madrid, Not set

Research Site, Málaga, Not set

Research Site, Valencia, Not set

Research Site, Ankara, Not set

Research Site, Istanbul, Not set

Research Site, Kayseri, Not set

Research Site, Umraniye, Not set

Research Site, Birmingham, Not set

Research Site, Bristol, Not set

Research Site, Liverpool, Not set

Research Site, London, Not set

Research Site, Manchester, Not set

Research Site, Southampton, Not set

Conditions: Systemic Lupus Erythematosus

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A Study of CC-97540, CD-19-Targeted Nex-T CAR T Cells, in Participants With Severe, Refractory Autoimmune Diseases (Breakfree-1)

NCT05869955

Recruiting

The purpose of this study is to establish the tolerability, preliminary efficacy, and pharmacokinetics of CC-97540 in participants with severe, refractory autoimmune diseases (Breakfree-1).

Gender:

ALL

Ages:

18 years and above

Trial Updated:

03/03/2025

Locations: University of Colorado Anschutz Medical Campus, Aurora, Colorado +53 locations

University of Colorado Anschutz Medical Campus, Aurora, Colorado

Colorado Blood Cancer Institute, Denver, Colorado

Local Institution - 0048, New Haven, Connecticut

Mayo Clinic in Florida, Jacksonville, Florida

University of Miami Hospital and Clinics, Sylvester Cancer Center, Miami, Florida

Local Institution - 0053, Chicago, Illinois

Local Institution - 0030, Baltimore, Maryland

Local Institution - 0038, Boston, Massachusetts

Local Institution - 0046, Boston, Massachusetts

Local Institution - 0033, Worcester, Massachusetts

University of Massachusetts Chan Medical School, Worcester, Massachusetts

University of Michigan, Ann Arbor, Michigan

Local Institution - 0037, Detroit, Michigan

Mayo Clinic in Rochester, Minnesota, Rochester, Minnesota

Local Institution - 0010, Saint Louis, Missouri

University Of Nebraska Medical Center, Omaha, Nebraska

Atlantic Health System Overlook Medical Center, Summit, New Jersey

NYU Langone Health, New York, New York

Local Institution - 0054, New York, New York

Icahn School of Medicine at Mount Sinai, New York, New York

Columbia University Irving Medical Center, New York, New York

Local Institution - 0055, New York, New York

The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina

Cleveland Clinic, Cleveland, Ohio

Local Institution - 0027, Columbus, Ohio

UT Southwestern Medical Center, Dallas, Texas

The University of Texas Health Science Center at Houston, Houston, Texas

University of Texas MD Anderson Cancer Center, Houston, Texas

Local Institution - 0057, Seattle, Washington

Local Institution - 0058, Seattle, Washington

Swedish Medical Center, Seattle, Washington

UZ Leuven, Leuven, Vlaams-Brabant

Local Institution - 0043, Strasbourg, Alsace

CHU Bordeaux Haut-Leveque, Pessac, Aquitaine

CHU Montpellier Lapeyronie Hospital, Montpellier, Hérault

Hopital Claude Huriez - CHU de Lille, Lille, Not set

Centre Hospitalier Universitaire de Nice - Hôpital l'Archet, Nice, Not set

Hôpital Saint-Louis, Paris, Not set

Local Institution - 0052, Paris, Not set

Centre Hospitalier Universitaire de Rennes - Hôpital Pontchaillou, Rennes, Not set

Universitaetsklinikum Wuerzburg, Wuerzburg, Bayern

Universitaetsklinikum Koeln, Köln, Nordrhein-Westfalen

Local Institution - 0045, Magdeburg, Sachsen-Anhalt

Universitätsklinikum Leipzig, Leipzig, Sachsen

Charité Universitaetsmedizin Berlin - Campus Mitte, Berlin, Not set

Universitaetsklinikum Duesseldorf, Düsseldorf, Not set

Universitaetsklinikum Erlangen, Erlangen, Not set

Fondazione Policlinico Universitario Agostino Gemelli IRCCS - Universita Cattolica del Sacro Cuore, Roma, Lazio

Local Institution - 0023, Rozzano, Milano

Hospital Universitari Vall d'Hebron, Barcelona, Barcelona [Barcelona]

Hospital Universitario Marqués de Valdecilla, Santander, Cantabria

Hospital Clínic de Barcelona, Barcelona, Catalunya [Cataluña]

Hospital Universitario Reina Sofia, Cordoba, Not set

H.R.U Málaga - Hospital General, Málaga, Not set

Conditions: Systemic Lupus Erythematosus, Idiopathic Inflammatory Myopathy, Systemic Sclerosis

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Rheumatology Patient Registry and Biorepository

NCT04402086

Recruiting

To facilitate clinical, basic science, and translational research projects involving the study of rheumatic diseases.

Gender:

ALL

Ages:

Between 18 years and 99 years

Trial Updated:

03/03/2025

Locations: Yale New Haven Hospital, New Haven, Connecticut

Conditions: Rheumatic Diseases, Adult Onset Still Disease, Ankylosing Spondylitis, Psoriatic Arthritis, Reactive Arthritis, Antiphospholipid Syndrome, Systemic Lupus Erythematosus, Behcet Disease, Dermatomyositis, Polymyositis, Giant Cell Arteritis, Lyme Disease, Mixed Connective Tissue Disease, Polymyalgia Rheumatica, Rheumatoid Arthritis, Sarcoidosis, Systemic Sclerosis, Scleroderma, Sjogren's Syndrome, Undifferentiated Connective Tissue Diseases

Learn More ›

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