Systemic Lupus Erythematosus Clinical Trials

A listing of 45 Systemic Lupus Erythematosus clinical trials actively recruiting volunteers for paid trials and research studies in various therapeutic areas.

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There are currently 45 active clinical trials seeking participants for Systemic Lupus Erythematosus research studies. The states with the highest number of trials for Systemic Lupus Erythematosus participants are California, Florida, Texas and New York.

Featured Trial

Paid Clinical Studies Nationwide

Recruiting

Nationwide clinical trials offered in your area. Some trials offering up to several thousand dollars in compensation for participation.

Conditions:

Healthy

Healthy Volunteer Study

Learn More

* Compensation for time may be available

Featured Trial

Chronic Cough Research Study

Recruiting

Are you tired of living with chronic cough? Our research study is now looking to enroll people from all backgrounds to help research potential new treatment options for chronic cough.
You are under no obligation to take part and health insurance is not required. Find out more today! We’d love to hear from you!

Conditions:

Chronic Cough

Refractory or Unexplained Chronic Cough

Cough

Asthma

Sinusitis

Learn More

Featured Offer

Lose Weight with GLP-1 Medications

Recruiting

Policy Lab has partnered with OnlineSemaglutide.org to offer trusted access to semaglutide and other GLP-1 medications, including generic alternatives to Ozempic® and Wegovy®.

GLP-1 medications are scientifically backed to help individuals achieve significant weight loss—on average, 15-20% of body weight within a year.

As a valued user, you’re eligible for $100 off your first program with code policy-lab-100.

Conditions:

Overweight

Overweight and Obesity

Obesity

Weight Loss

Morbid Obesity

Learn More

Featured Trial

Lupus Nephritis Clinical Study

Recruiting

The Ntrust-1 study is part of a broad effort of the global research community to develop more treatment options for people living with lupus nephritis (LN). You may be eligible to participate in this study if you:
 Are 18 to 65 years old.
 Have been diagnosed with lupus nephritis.
 Have received at least two prior therapies for lupus nephritis.

Conditions:

Lupus

Systemic Lupus Erythematosus

Lupus Nephritis

Lupus Erythematosus

Systemic

Learn More

BAFF CAR-T Cells (LMY-920) for Systemic Lupus Erythematosus

NCT06340750

Recruiting

This phase 1 study seeks to examine the safety and recommended phase 2 dose (RP2D) of BAFF-ligand CAR-T cells (LMY-920) in adult patients with refractory systemic lupus erythematosus (SLE). It is hypothesized that BAFF CAR-T cells will be safe and will improve SLE disease activity scores.

Gender:

ALL

Ages:

Between 18 years and 65 years

Trial Updated:

05/28/2025

Locations: Nationwide Children's, Columbus, Ohio

Conditions: Systemic Lupus Erythematosus

Learn More ›

A Study to Evaluate Effectiveness and Safety of Deucravacitinib (BMS-986165) Compared With Placebo in Participants With Active Systemic Lupus Erythematosus

NCT05620407

Recruiting

The purpose of this study is to evaluate the effectiveness and safety of deucravacitinib compared with placebo in an active moderate to severe Systemic Lupus Erythematosus (SLE) population.

Gender:

ALL

Ages:

Between 18 years and 75 years

Trial Updated:

08/18/2025

Locations: Local Institution - 0237, Searcy, Arkansas +206 locations

Local Institution - 0237, Searcy, Arkansas

UCSD - Altman Clinical and Translational Research Institute (ACTRI), La Jolla, California

Local Institution - 0241, San Diego, California

Rheumatology Center of San Diego, San Diego, California

East Bay Rheumatology Medical Group, Inc, San Leandro, California

Providence Saint John's Medical Foundation, Santa Monica, California

Clinical Research of West Florida, Inc. (Clearwater), Clearwater, Florida

UF Health Deerwood Park, Jacksonville, Florida

Life Clinical Trials, Margate, Florida

Nuline Clinical Trial Center, Oakland Park, Florida

Local Institution - 0239, Plant City, Florida

Emory University School of Medicine- Grady Campus, Atlanta, Georgia

Atlanta Research Center for Rheumatology, Marietta, Georgia

Greater Chicago Specialty Physicians - Orland Park, Orland Park, Illinois

Local Institution - 0041, Skokie, Illinois

Local Institution - 0231, New Orleans, Louisiana

Massachusetts General Hospital, Boston, Massachusetts

Beth Israel Deaconess Medical Center, Boston, Massachusetts

University of Massachusetts Chan Medical School, Worcester, Massachusetts

AA Medical Research Center-Grand Blanc, Grand Blanc, Michigan

Mayo Clinic in Rochester, Minnesota, Rochester, Minnesota

Local Institution - 0200, Las Vegas, Nevada

Local Institution - 0216, Las Vegas, Nevada

The Valley Hospital, Inc., Paramus, New Jersey

Joseph S. and Diane H. Steinberg Ambulatory Care Center, Brooklyn, New York

Irving Goldman Family Care Center, Great Neck, New York

Hospital for Special Surgery, New York, New York

Columbia University Medical Center, New York, New York

SUNY Upstate Medical University, Syracuse, New York

Local Institution - 0178, Charlotte, North Carolina

University of Cincinnati Medical Center, Cincinnati, Ohio

University Hospitals Cleveland Medical Center, Cleveland, Ohio

Oklahoma Medical Research Foundation, Oklahoma City, Oklahoma

Temple University Hospital, Philadelphia, Pennsylvania

West Penn Allegheny Health, Pittsburgh, Pennsylvania

Local Institution - 0081, Charleston, South Carolina

Hope Health, Florence, South Carolina

Local Institution - 0228, Florence, South Carolina

West Tennessee Research Institute, Jackson, Tennessee

Austin Regional Clinic, Austin, Texas

Local Institution - 0001, Colleyville, Texas

Texas Arthritis Center, El Paso, Texas

Biopharma Informatic, LLC, Katy, Texas

Baylor Scott & White Medical Center - Temple, Temple, Texas

Spectrum Medical, Inc., Danville, Virginia

Sanatorio Guemes, Ciudad de Buenos Aires, Buenos Aires

Hospital El Cruce, Florencio Varela, Buenos Aires

Hospital Italiano de La Plata, La Plata, Buenos Aires

Centro de Investigacion Pergamino S.A., Pergamino, Buenos Aires

Hospital Universitario Austral, Pilar, Buenos Aires

Centro de Investigaciones San Miguel, San Miguel, Buenos Aires

CER medical Institute, Quilmes, Ciudad Autónoma De Buenos Aires

Centro de Investigaciones Médicas Tucuman, SAN M. DE Tucuman, Tucumán

Centro Integral de Reumatologia, San Miguel de Tucumán, Tucumán

Local Institution - 0141, Río Cuarto, Not set

Liverpool Hospital, Liverpool, New South Wales

BJC Health, Paramatta, New South Wales

Rheumatology Research Unit, Maroochydore, Queensland

Austin Health - Repatriation Hospital, Ivanhoe, Victoria

RK Will Pty Ltd, Victoria Park, Western Australia

CEDOES, Vitória, Espírito Santo

Local Institution - 0232, Recife, Pernambuco

Hospital Bruno Born, Lajeado, Rio Grande Do Sul

Hospital de Clinicas de Porto Alegre, Porto Alegre, Rio Grande Do Sul

Hospital Moinhos de Vento, Porto Alegre, Rio Grande Do Sul

Instituto de Pesquisa e Ensino em Saúde - IPES, Porto Velho, Rondônia

Fundação Pio XII - Hospital de Câncer de Barretos, Barretos, São Paulo

Local Institution - 0095, Santo André, São Paulo

Centro Multidisciplinar de Estudos Clinicos, Sao Bernardo do Campo, São Paulo

Local Institution - 0033, Curitiba, Not set

Hospital São Lucas de Copacabana, Rio de Janeiro, Not set

Hospital Alemao Oswaldo Cruz, São Paulo, Not set

Hospital 9 De Julho, São Paulo, Not set

CEPIC - Centro Paulista de Investigação Clínica, São Paulo, Not set

Diagnostic Consultative Centre (DCC) - Foкus 5, Sofia, Sofia (stolitsa)

University Hospital Kaspela Clinic of Rheumatology, Plovdiv, Not set

Diagnostic Consultative Centre 1 Ruse, Ruse, Not set

Local Institution - 0214, Sofia, Not set

IC La Serena Research, La Serena, Coquimbo

Local Institution - 0099, Valdivia, Los Ríos

Estudios Clinicos CTR, Santiago, Región Metropolitana De Santiago

Biomedica Research Group, Santiago, Región Metropolitana De Santiago

Estudios Clinicos Limitada, Santiago, Región Metropolitana De Santiago

Local Institution - 0044, Santiago, Región Metropolitana De Santiago

Local Institution - 0098, Santiago, Región Metropolitana De Santiago

Pontificia Universidad Catolica de Chile, Santiago, Región Metropolitana De Santiago

Clínica Ensenada, Santiago, Región Metropolitana De Santiago

Local Institution - 0153, Santiago, Not set

INREA s.r.o., Ostrava, Ostrava Město

Revmatologicky ustav, Praha 2, Not set

General Hospital of Athens Hippokratio, Athens, Attikí (Region)

General Hospital of Athens "Laiko", Athens, Attikí

University General Hospital of Larissa, Larissa, Thessalía

Pécsi Tudományegyetem Klinikai Központ, Pécs, Baranya

Békés Vármegyei Központi Kórház Pándy Kálmán Tagkórház, Gyula, Békés

Szegedi Tudományegyetem Szent-Györgyi Albert Klinikai Központ, Szeged, Csongrád

Vital Medical Center, Veszprem, Veszprém City

Local Institution - 0197, New Delhi, Delhi

Local Institution - 0234, Ahmedabad, Gujarat

Local Institution - 0209, Ahmedabad, Gujarat

Ratan Multi-Speciality Hospital, Ahmedabad, Gujarat

Sushruta Multispeciality Hospital & Research Centre, Hubli, Karnataka

JSS Hospital, Mysore, Karnataka

Jasleen Hospital, Nagpur, Maharashtra

Christian Medical College Vellore, Vellore, Tamil Nadu

Local Institution - 0204, Vellore, Tamil Nadu

Local Institution - 0235, Hyderabad, Telangana

Krishna Institute of Medical Science, Secundarabad, Telangana

Koujunkai Daido Clinic, Nagoya, Aichi

Local Institution - 0156, Nagoya, Aichi

Fujita Health University, Toyoake, Aichi

Local Institution - 0086, Eiheiji-cho,Yoshida-gun, Fukui

University of Occupational and Enviromental Health, Kitakyushu, Fukuoka

National Hospital Organization Asahikawa Medical Center, Asahikawa, Hokkaido

Hokkaido University Hospital, Sapporo, Hokkaido

Kagawa University Hospital, Kita, Kagawa

Kitasato University Hospital, Sagamihara, Kanagawa

Yokohama City University Hospital, Yokohama, Kanagawa

Tohoku University Hospital, Sendai-shi, Miyagi

Sasebo Chuo Hospital, Sasebo, Nagasaki

Saitama Medical Center, Kawagoe, Saitama

Dokkyo Medical University Hospital, Shimotsuga, Tochigi

Juntendo University Hospital, Bunkyo-ku, Tokyo

Tokyo Medical and Dental University Hospital, Bunkyo-ku, Tokyo

Toho University Ohashi Medical Center, Meguro-ku, Tokyo

Center Hospital of the National Center for Global Health and Medicine, Shinjyuku-ku, Tokyo

Toyama University Hospital, Toyoma, Toyama

National Hospital Organization Chibahigashi National Hospital, Chiba, Not set

Kyushu University Hospital, Fukuoka, Not set

Fukushima Medical University, Fukushima, Not set

Gifu University Hospital, Gifu, Not set

Nagasaki University Hospital, Nagasaki, Not set

Niigata University Medical & Dental Hospital, Niigata, Not set

Okayama University Hospital, Okayama, Not set

Osaka Metropolitan University Hospital, Osaka, Not set

St. Luke's International Hospital, Tokyo, Not set

Keio university hospital, Tokyo, Not set

Wakayama Medical University Hospital, Wakayama, Not set

CIMAB SA de CV, Torreón, Coahuila

Local Institution - 0015, Cdmx, Distrito Federal

RM Pharma Specialists, Mexico city, Distrito Federal

CAIMED Investigacion en Salud, Mexico City, Distrito Federal

Centro de Investigacion Farmacologica del Bajio SC, Leon, Guanajuato

Boca Clinical Trials Mexico S.C., Guadajalara, Jalisco

Investigacion Biomedica para el Desarrollo de Fármacos S.A. de C.V., Zapopan, Jalisco

Local Institution - 0010, Cuernavaca, Morelos

Hospital Universitario "Dr. Jose Eleuterio Gonzalez", Monterrey, Nuevo LEON

Local Institution - 0096, Chihuahua, Not set

IMACEN S.A de C.V., Chihuahua, Not set

Oaxaca Site Management Organization, Oaxaca, Not set

Local Institution - 0100, Lima, Not set

Instituto Peruano del Hueso y la Articulación, Lima, Not set

ACQ Medic SAC - Centro de Investigación Clinica Inmunoreumatología, Lima, Not set

Local Institution - 0093, Lima, Not set

Clinica San Juan Bautista, Lima, Not set

Clinica Medica Cayetano Heredia, Lima, Not set

Local Institution - 0218, Wroclaw, Dolnośląskie

Zespół Poradni Specjalistycznych Reumed Filia nr 1 Wallenroda, Lublin, Lubelskie

Centrum Medyczne Reuma Park, Warszawa, Mazowieckie

Synexus Polska Sp. z o.o. Oddzial w Warszawie, Warszawa, Mazowieckie

Futuremeds Targowek, Warszawa, Mazowieckie

Pratia MCM Krakow, Kraków, Małopolskie

Local Institution - 0016, Elbląg, Warmińsko-mazurskie

Ortopedyczno-Rehabilitacyjny Szpital Kliniczny UM w Poznaniu, Poznan, Wielkopolskie

Centrum Wsparcia Badań Klinicznych Pomorskiego Uniwersytetu Medycznego w Szczecinie, Szczecin, Not set

MICS Centrum Medyczne Warszawa, Warszawa, Not set

Local Institution - 0031, Wroclaw, Not set

SOMED CR, Lodz, Łódzkie

M2M Med, Chorzów, Śląskie

Centro Hospitalar Universitário Lisboa Norte, E.P.E. - Hospital de Santa Maria, Lisbon, Lisboa

Unidade Local De Saude De Gaia/Espinho E.P.E., Vila Nova de Gaia, Porto

Instituto Portugues de Reumatologia, Lisbon, Not set

Hospital Professor Doutor Fernando Fonseca, Lisbon, Not set

Local Institution - 0240, Caguas, Not set

Latin Clinical Trial Center, San Juan, Not set

Singapore General Hospital, Singapore, Not set

Local Institution - 0127, Singapore, Not set

Hospital de Mérida, Mérida, Badajoz

Hospital Universitari Vall d'Hebron, Barcelona, Barcelona [Barcelona]

Hospital Universitario Marqués de Valdecilla, Santander, Cantabria

Hospital Universitario Reina Sofia, Cordoba, Madrid

Osi Bilbao-Basurto, Bilbo, País Vasco

Local Institution - 0055, Vitoria-Gasteiz, País Vasco

Hospital Quironsalud Infanta Luisa, Sevilla, Not set

Hospital Universitario Rio Hortega, Valladolid, Not set

Hospital Universitari i Politecnic La Fe, València, Not set

Chang Gung Memorial Hospital at Kaohsiung, Kaohsiung Niao Sung Dist, Kaohsiung

Chung Shan Medical University Hospital, Taichung City, Taichung

China Medical University Hospital, Taichung, Not set

Taichung Veterans General Hospital, Taichung, Not set

Chi Mei Medical Center, Tainan City, Not set

National Taiwan University Hospital, Taipei, Not set

Taipei Veterans General Hospital, Taipei, Not set

Local Institution - 0207, Bangkok, Krung Thep Maha Nakhon

Ramathibodi Hospital, Bangkok, Krung Thep Maha Nakhon

Faculty of Medicine Siriraj Hospital, Bangkok, Krung Thep Maha Nakhon

Hacettepe Universite Hastaneleri, Ankara, Not set

Akdeniz Universitesi Hastanesi, Antalya, Not set

NCR International Hospital, Gaziantep, Not set

Local Institution - 0170, Istanbul, Not set

Royal Free Hospital, London, England

Local Institution - 0236, Larbert, Falkirk

King's College Hospital, London, Greater London

Guy's & St Thomas' NHS Foundation Trust, London, London, City Of

Local Institution - 0168, Central Middlesbrough, Middlesbrough

Local Institution - 0092, Bradford, Not set

Oxford University Hospitals - Nuffield Orthopaedic Centre, Oxford, Not set

Conditions: Systemic Lupus Erythematosus

Learn More ›

Program to Assess Adverse Events and Change in Disease Activity of Oral Upadacitinib in Adult Participants With Moderate to Severe Systemic Lupus Erythematosus

NCT05843643

Recruiting

Systemic Lupus Erythematosus (SLE) is an immune-mediated disease associated with inflammation of multiple organ systems. This study will assess how safe and effective upadacitinib is in treating adult participants with moderately to severely active SLE. Adverse events and change in the disease activity will be assessed. Upadacitinib is an approved drug for rheumatoid arthritis, psoriatic arthritis, and axial spondylarthritis and is being developed for the treatment of SLE. This study is "double... Read More

Gender:

ALL

Ages:

Between 18 years and 63 years

Trial Updated:

08/18/2025

Locations: AZ Arthritis and Rheumatology /ID# 261848, Chandler, Arizona +351 locations

AZ Arthritis and Rheumatology /ID# 261848, Chandler, Arizona

AZ Arthritis and Rheumotology Research, PLLC - Flagstaff /ID# 254767, Flagstaff, Arizona

Arizona Arthritis & Rheumatology Research, PLLC /ID# 252820, Gilbert, Arizona

Arizona Arthritis and Rheumatology Research - Glendale Office /ID# 252824, Glendale, Arizona

Arizona Arthritis & Rheumatology Research, PLLC /ID# 261845, Mesa, Arizona

Arizona Arthritis & Rheumatology Research /ID# 273555, Peoria, Arizona

Arizona Arthritis & Rheumatology Associates - East Bell Road /ID# 252831, Phoenix, Arizona

Arizona Arthritis & Rheumatology Research, PLLC /ID# 252825, Phoenix, Arizona

HonorHealth Rheumatology /ID# 261953, Scottsdale, Arizona

Arizona Arthritis & Rheumatology Associates - Tucson /ID# 252828, Tucson, Arizona

Arthritis and Rheumatism Associates /ID# 253033, Jonesboro, Arkansas

Kaiser Permanente Lakeview Medical Offices /ID# 253906, Anaheim, California

David S. Hallegua MD, A Professional Corporation /ID# 253902, Beverly Hills, California

Wallace Rheumatic Studies Center, LLC /ID# 252806, Beverly Hills, California

Advanced Clinical Research Center, LLC dba TriWest Research Associates /ID# 272870, Chula Vista, California

Providence - St. Jude Medical Center /ID# 252822, Fullerton, California

Private Practice - Dr. Chandrakant V. Mehta /ID# 275100, Hemet, California

Newport Huntington Medical Group /ID# 252827, Huntington Beach, California

Moores Cancer Center at UC San Diego /ID# 253903, La Jolla, California

Arthritis & Osteo Medical Ctr /ID# 252812, La Palma, California

Wagdy Kades, M.D., Inc /ID# 272065, Los Angeles, California

Providence St. John's Health Center /ID# 253905, Santa Monica, California

Millennium Clinical Trials /ID# 252817, Thousand Oaks, California

Cohen Medical Centers /ID# 268524, Thousand Oaks, California

Solace Research /ID# 275198, Tustin, California

Upland Rheumatology Center /ID# 268623, Upland, California

University of Colorado Hospital /ID# 253184, Aurora, Colorado

Denver Arthritis Clinic /ID# 253189, Denver, Colorado

Yale University School of Medicine /ID# 254567, New Haven, Connecticut

Arthritis and Rheumatic Disease Specialties /ID# 253624, Aventura, Florida

HARAC Research Corp. /ID# 254922, Avon Park, Florida

Rheumatology Associates of South Florida (RASF) - Clinical Research /ID# 253623, Boca Raton, Florida

Bay Area Arthritis and Osteo /ID# 253597, Brandon, Florida

GNP Consultants, dba, GNP Research /ID# 272868, Cooper City, Florida

Duplicate_Believe Clinical Trials /ID# 255427, Coral Springs, Florida

International Medical Research /ID# 253617, Daytona Beach, Florida

Omega Research Debary, LLC /ID# 254939, DeBary, Florida

University of Florida /ID# 261984, Gainesville, Florida

Finlay Medical Research - Greenacres /ID# 274902, Greenacres City, Florida

Evolution Research Center /ID# 272991, Hialeah, Florida

Neoclinical Research /ID# 253614, Hialeah, Florida

South Florida Rheumatology /ID# 268525, Hollywood, Florida

Encore Research Group-Jacksonville Center for Clinical Research /ID# 257272, Jacksonville, Florida

UF Health Rheumatology /ID# 255351, Jacksonville, Florida

Life Clinical Trials /ID# 253615, Margate, Florida

Lakes Research, LLC /ID# 253621, Miami, Florida

University of Miami, Division of Rheumatology /ID# 261594, Miami, Florida

HMD Research LLC /ID# 253595, Orlando, Florida

University of Central Florida /ID# 261112, Orlando, Florida

Millennium Research /ID# 253600, Ormond Beach, Florida

Vitalia Research /ID# 272642, Palm Beach Gardens, Florida

IRIS Research and Development, LLC /ID# 253618, Plantation, Florida

BayCare Medical Group /ID# 253593, Saint Petersburg, Florida

Clinical Research Of West Florida - Tampa - North Howard Avenue /ID# 253602, Tampa, Florida

Clinical Research Of West Florida - Tampa - North Howard Avenue /ID# 253899, Tampa, Florida

Baycare Medical Group - Tampa /ID# 255135, Tampa, Florida

Emory University School Of Medicine - Atlanta /ID# 261529, Atlanta, Georgia

Trinity Research Centers /ID# 262039, Kennesaw, Georgia

Atlanta Research Center For Rheumatology - Marietta /ID# 253610, Marietta, Georgia

University of Illinois at Chicago /ID# 263014, Chicago, Illinois

Northwestern University Feinberg School of Medicine /ID# 264090, Chicago, Illinois

Next Innovative Clinical Research - Chicago /ID# 268739, Chicago, Illinois

University of Chicago Medical Center /ID# 263162, Chicago, Illinois

Deerbrook Medical Associates /ID# 253029, Libertyville, Illinois

Illinois Bone & Joint Institute - Morton /ID# 274455, Morton, Illinois

Advanced Quality Medical Research /ID# 254983, Orland Park, Illinois

OrthoIllinois /ID# 253188, Rockford, Illinois

Greater Chicago Specialty Physicians /ID# 253021, Schaumburg, Illinois

Clinic Of Dr. Robert Hozman/Clinical Investigation Specialists, Inc /ID# 253020, Skokie, Illinois

NorthShore University HealthSystem - Skokie /ID# 254568, Skokie, Illinois

Willow Rheumatology and Wellness, PLLC /ID# 253018, Willowbrook, Illinois

Western KY Rheumatology /ID# 254937, Hopkinsville, Kentucky

Accurate Clinical Research (SMO/Network/Consortium) /ID# 272647, Lake Charles, Louisiana

Willis Knighton /ID# 256343, Shreveport, Louisiana

University of Maryland, Baltimore /ID# 262556, Baltimore, Maryland

UMass Memorial Medical Center /ID# 262742, Worcester, Massachusetts

Clinical Research Institute Of Michigan /ID# 273051, Clinton Township, Michigan

AA Medical Research Center - Grand Blanc /ID# 253028, Grand Blanc, Michigan

June DO, PC /ID# 253030, Lansing, Michigan

Kansas City Physician Partners /ID# 254786, Kansas City, Missouri

Logan Health Research - Glacier View Research Institute - Rheumatology /ID# 252808, Kalispell, Montana

Dartmouth-Hitchcock Medical Center /ID# 254923, Lebanon, New Hampshire

Arthritis and Osteoporosis Associates of New Mexico /ID# 252818, Las Cruces, New Mexico

Inspire Santa Fe Medical Group /ID# 275947, Santa Fe, New Mexico

Urban Health Plan /ID# 268059, Bronx, New York

Joseph S. and Diane H. Steinberg Ambulatory Care Center /ID# 253592, Brooklyn, New York

NYU Langone Orthopedic Center /ID# 253613, New York, New York

St. Lawrence Health System /ID# 253598, Potsdam, New York

Joint And Muscle Research Institute /ID# 272845, Charlotte, North Carolina

DJL Clinical Research, PLLC /ID# 253620, Charlotte, North Carolina

Raleigh Medical Group /ID# 256328, Raleigh, North Carolina

Accellacare - Salisbury /ID# 253608, Salisbury, North Carolina

Atrium Health Wake Forest Baptist Medical Center /ID# 254125, Winston-Salem, North Carolina

University of Cincinnati Medical Center /ID# 259174, Cincinnati, Ohio

Paramount Medical Research and Consulting /ID# 253016, Middleburg Heights, Ohio

Clinical Research Source, Inc. /ID# 253027, Perrysburg, Ohio

Oklahoma Medical Research Foundation /ID# 263509, Oklahoma City, Oklahoma

Rheumatology Associates of Oklahoma /ID# 253012, Oklahoma City, Oklahoma

Clinical Research of Philadelphia, LLC /ID# 254156, Philadelphia, Pennsylvania

Albert Einstein Medical Center /ID# 256661, Philadelphia, Pennsylvania

University of Pittsburgh Medical Center /ID# 263686, Pittsburgh, Pennsylvania

Low Country Rheumatology /ID# 272956, Summerville, South Carolina

West Tennessee Research Institute /ID# 252807, Jackson, Tennessee

Shelby Research /ID# 256937, Memphis, Tennessee

Arthritis and Rheumatology Research Institute, PLLC /ID# 253014, Allen, Texas

Arthritis Care of Texas /ID# 261719, Corpus Christi, Texas

JPS Rheumatology Clinic /ID# 253185, Fort Worth, Texas

Arthiritis and Rheumatology Specialists PA /ID# 255950, Fort Worth, Texas

Integrative Rheumatology of South Texas - Harlingen /ID# 261977, Harlingen, Texas

Accurate Clinical Research - Houston /ID# 276220, Houston, Texas

R & H Clinical Research - 777 Katy /ID# 254126, Katy, Texas

Biopharma Informatic /ID# 273651, Katy, Texas

Valley Arthritis Center /ID# 253022, McAllen, Texas

Texas Rheumatology Research Institute Llc /Id# 253013, Plano, Texas

Epic Medical Research /ID# 255326, Red Oak, Texas

Sun Research Institute /ID# 255832, San Antonio, Texas

Clinical Trials of Texas, Inc /ID# 254949, San Antonio, Texas

Fort Bend Rheumatology Associates, PLLC /ID# 268492, Sugar Land, Texas

DM Clinical Research - Tomball /ID# 255134, Tomball, Texas

Carilion Clinic /ID# 253374, Roanoke, Virginia

Rheumatology & Pulmonary Clinic /ID# 273561, Beckley, West Virginia

Wisconsin Medical Center /ID# 256660, Milwaukee, Wisconsin

Fundación Sanatorio Guemes /ID# 254283, Ciudad Autonoma Buenos Aires, Buenos Aires

Hospital Militar Central Cirujano Mayor Dr. Cosme Argerich /ID# 254278, Ciudad Autonoma Buenos Aires, Buenos Aires

Hospital Italiano La Plata /ID# 254284, La Plata, Buenos Aires

CER Instituto Medico /ID# 255302, Quilmes, Buenos Aires

Organizacion Medica de Investigacion (OMI) /ID# 254281, Ciudad Autonoma de Buenos Aire, Ciudad Autonoma De Buenos Aires

Fundacion CIDEA /ID# 254279, Ciudad Autonoma de Buenos Aire, Ciudad Autonoma De Buenos Aires

Instituto Medico Especializado /ID# 255281, Ciudad Autonoma de Buenos Aire, Ciudad Autonoma De Buenos Aires

Aprillus Asistencia e Investigacion /ID# 254276, Ciudad Autonoma de Buenos Aire, Ciudad Autonoma De Buenos Aires

Instituto CAICI S.R.L /ID# 254280, Rosario, Santa Fe

Centro de Investigaciones Medicas Tucuman /ID# 254274, San Miguel de Tucuman, Tucuman

Emeritus Research Sydney /ID# 256249, Botany, New South Wales

Concord Repatriation General Hospital /ID# 257945, Concord, New South Wales

Momentum Clinical Research /ID# 253542, Darlinghurst, New South Wales

Royal Darwin Hospital /ID# 263160, Tiwi, Northern Territory

The Queen Elizabeth Hospital /ID# 253826, Woodville, South Australia

Emeritus Research /ID# 256800, Camberwell, Victoria

Monash Health - Monash Medical Centre /ID# 255678, Clayton, Victoria

Colin Bayliss Research and Teaching Unit /ID# 261077, Victoria Park, Western Australia

ZAS Palfijn /ID# 252802, Merksem, Antwerpen

Universite Libre de Bruxelles - Hopital Erasme /ID# 261997, Anderlecht, Bruxelles-Capitale

Universitair Ziekenhuis Brussel /ID# 269065, Jette, Bruxelles-Capitale

Institute of Physical Medicine,Rehab. and Orthopedic Surgery Dr.Miroslav Zotovic /ID# 262588, Banja Luka, Republika Srpska

Klinicki centar Banja Luka /ID# 253581, Banja Luka, Republika Srpska

Klinicki centar Banja Luka /ID# 253582, Banja Luka, Republika Srpska

Clinical Center University of Sarajevo /ID# 253583, Sarajevo, Not set

Polyclinic Srce Sarajeva /ID# 255475, Sarajevo, Not set

SER - Servicos Especializados em Reumatologia da Bahia /ID# 253354, Salvador, Bahia

CEDOES - Centro de Diagnóstico e Pesquisa da Osteoporose do Espírito Santo /ID# 254588, Vitoria, Espirito Santo

CMiP - Centro Mineiro de Pesquisa Ltda - ME /ID# 253346, Juiz de Fora, Minas Gerais

EDUMED Educacao em Saude S/S LTDA /ID# 253274, Curitiba, Parana

Hospital de Clinicas de Porto Alegre /ID# 253357, Porto Alegre, Rio Grande Do Sul

LMK Sevicos Medicos S/S /ID# 253353, Porto Alegre, Rio Grande Do Sul

Fundacao Faculdade Regional de Medicina de Sao Jose do Rio Preto /ID# 261024, Sao Jose Do Rio Preto, Sao Paulo

Hospital do Rim /ID# 253983, Sao Paulo, Not set

Hospital das Clinicas da Faculdade de Medicina da Universidade de Sao /ID# 254316, Sao Paulo, Not set

Mc Excelsior /ID# 272499, Sofiya, Sofia

Diagnostic Consultative Centre (Dcc) - Foкus 5 /ID# 252642, Sofiya, Sofia

Diagnostic Consultative Centre (Dcc) - Foкus 5 /ID# 252643, Sofiya, Sofia

Umbal Kaspela /ID# 252645, Plovdiv, Not set

Medical Center Artmed Ltd /Id# 254572, Plovdiv, Not set

Medical center Unimed /ID# 253324, Plovdiv, Not set

Medical center Teodora /ID# 252646, Ruse, Not set

Military Medical Academy Multiprofile Hospital /ID# 252644, Sofia, Not set

Medical Center Academy /ID# 253322, Sofia, Not set

University of Calgary /ID# 259515, Calgary, Alberta

University of Alberta Hospital /ID# 259516, Edmonton, Alberta

University of Manitoba /ID# 259517, Winnipeg, Manitoba

Toronto Western Hospital /ID# 254017, Toronto, Ontario

CIUSSS de l'Estrie - CHUS /ID# 254716, Sherbrooke, Quebec

Servicio de Salud Araucanía Norte Hospital Victoria /ID# 255179, Victoria, Araucania

Hospital Guillermo Grant Benavente de Concepción /ID# 254841, Concepción, Bio-Bio

Inmunocel /Id# 256390, Las Condes, Region Metropolitana De Santiago

Centro Internacional de Estudios Clinicos - CIEC /ID# 254838, Santiago, Region Metropolitana Santiago

Investigaciones Medicas Limitada /Id# 254842, Providencia, Not set

The first affiliated hospital of bengbu medical college /ID# 252853, Bengbu, Anhui

China-Japan Friendship Hospital /ID# 253048, Beijing, Beijing

Peking University Third Hospital /ID# 253138, Beijing, Beijing

Peking Union Medical College Hospital (East) - Dongdan Campus /ID# 253045, Beijing, Beijing

The First Affiliated Hospital of Xiamen University /ID# 252630, Xiamen, Fujian

Guangdong Provincial Peoples Hospital /ID# 252920, Guangzhou, Guangdong

The First Affiliated Hospital, Sun Yat-sen University /ID# 252921, Guangzhou, Guangdong

Sun Yat-sen Memorial Hospital of Sun Yat-sen University /ID# 253137, Guangzhou, Guangdong

The First Affiliated Hospital Of Guangzhou Medical University /ID# 252927, Guangzhou, Guangdong

The Third Affiliated Hospital, Sun Yat-Sen University /ID# 252923, Guangzhou, Guangdong

The First Affiliated Hospital of Shantou University Medical College /ID# 253426, Shantou, Guangdong

The First Affiliated Hospital Of Guangxi Medical University /ID# 272798, Nanning, Guangxi

The First Affiliated Hospital Of Henan University Of Science &Technology /ID# 272929, Luoyang, Henan

Union Hospital Tongji Medical College Huazhong University of Science and Technol /ID# 252963, Wuhan, Hubei

Tongji Hospital Tongji Medical College of HUST /ID# 252632, Wuhan, Hubei

Zhuzhou Central Hospital /ID# 252962, Zhuzhou, Hunan

The Affiliated Hospital of Inner Mongolia Medical University /ID# 252629, Huhehaote, Inner Mongolia

The First People's Hospital of Changzhou /ID# 252992, Changzhou, Jiangsu

Nanjing Drum Tower Hospital /ID# 253042, Nanjing, Jiangsu

Affiliated hospital of nantong university /ID# 252991, Nantong, Jiangsu

Wuxi People's Hospital /ID# 253858, Wuxi, Jiangsu

Xuzhou Central Hospital /ID# 252922, Xuzhou, Jiangsu

Yancheng First People's Hospital /ID# 254599, Yancheng, Jiangsu

Northern Jiangsu People's Hospital /ID# 252945, Yangzhou, Jiangsu

The First People's Hospital of Jiujiang /ID# 252989, Jiujiang, Jiangxi

Jiangxi Provincial People's Hospital /ID# 252940, Nanchang, Jiangxi

Jiangxi Pingxiang People's Hospital /ID# 252919, Pingxiang, Jiangxi

The First Hospital of Jilin University /ID# 252771, Changchun, Jilin

Second Affiliated Hospital of Xian Jiaotong University /ID# 252861, Xi'an, Shaanxi

Jining No.1 People's Hospital /ID# 252897, Jining, Shandong

Linyi People's Hospital /ID# 252898, Linyi, Shandong

Renji Hospital, Shanghai Jiaotong University School of Medicine /ID# 263435, Shanghai, Shanghai

West China Hospital, Sichuan University /ID# 252854, Chengdu, Sichuan

Mianyang Central Hospital /ID# 272850, Mianyang, Sichuan

Tianjin Medical University General Hospital /ID# 252868, Tianjin, Tianjin

People's Hospital of Xinjiang Uygur Autonomous Region /ID# 266897, Urumqi, Xinjiang

First Affiliated Hospital of Kunming Medical University /ID# 252925, Kunming, Yunnan

The First Affiliated Hospital, Zhejiang University School of Medicine /ID# 252633, Hangzhou, Zhejiang

Zhejiang Provincial People's Hospital /ID# 253860, Hangzhou, Zhejiang

The First Affiliated Hospital of Wenzhou Medical University /ID# 253649, Wenzhou, Zhejiang

IPS Suramericana SAS - IPS Sura San Diego /ID# 261536, Medellín, Antioquia

Hospital Pablo Tobón Uribe /ID# 254101, Medellín, Antioquia

Centro de Investigacion en Reumatologia y especialidades Medicas S.A.S- CIREEM /ID# 254097, Bogotá, Cundinamarca

Healthy Medical Center S.A.S /ID# 254098, Zipaquirá, Cundinamarca

Fundacion Oftalmologica de Santander - FOSCAL /ID# 254100, Bucaramanga, Santander

Clinica de la Costa S.A.S /ID# 260727, Barranquilla, Not set

Poliklinika Bonifarm /ID# 252846, Zagreb, Grad Zagreb

Poliklinika Solmed /ID# 252965, Zagreb, Grad Zagreb

Klinicki bolnicki centar Osijek /ID# 252847, Osijek, Osjecko-baranjska Zupanija

Klinicki bolnicki centar Rijeka /ID# 252848, Rijeka, Primorsko-goranska Zupanija

Klinicki Bolnicki Centar (KBC) Split /ID# 252849, Split, Splitsko-dalmatinska Zupanija

Opća Bolnica Zadar /ID# 272415, Zadar, Zadarska Zupanija

Innomedica /ID# 253722, Tallinn, Harjumaa

East Tallinn Central Hospital - Magdaleena Unit /ID# 253721, Tallinn, Harjumaa

North Estonia Medical Centre Foundation /ID# 253723, Tallinn, Harjumaa

MediTrials /ID# 253720, Tartu, Tartumaa

CHU Toulouse - Hopital Rangueil /ID# 254148, Toulouse, Haute-Garonne

Hopital Pitie Salpetriere /ID# 253009, Paris Cedex 13, Ile-de-France

HCL - Hopital de la Croix-Rousse /ID# 254147, Lyon, Rhone

Krankenhaus Porz am Rhein /ID# 254373, Cologne, Nordrhein-Westfalen

Universitaetsmedizin Mainz /ID# 260735, Mainz, Rheinland-Pfalz

Universitaetsklinikum Carl Gustav Carus Dresden /ID# 270832, Dresden, Sachsen

Immanuel Krankenhaus Berlin /ID# 253389, Berlin-buch, Not set

Fraunhofer Institute for Translational Medicine & Pharmacology ITMP /ID# 253734, Frankfurt am Main, Not set

General Hospital of Athens Laiko /ID# 252952, Athens, Attiki

University General Hospital Attikon /ID# 253209, Athens, Attiki

University General Hospital of Heraklion PA.G.N.I /ID# 252951, Heraklion, Kriti

Clinica Medica Especializada en Medicina Interna y Reumatologia /ID# 261156, Guatemala, Not set

Clinica Medica Reumatologica /ID# 255009, Guatemala, Not set

Clinica Especializada en Medicina Interna /ID# 255006, Guatemala, Not set

Clínica Médica Especializada en Medicina Interna y Reumatologia /ID# 257248, Guatemala, Not set

Pecsi Tudomanyegyetem Klinikai Kozpont /ID# 254552, Pecs, Baranya

Vital-Medicina Kft. /ID# 252876, Veszprém, Fejer

Debreceni Egyetem-Klinikai Kozpont /ID# 252877, Debrecen, Hajdu-Bihar

Vita Verum Medical Bt. /ID# 273579, Székesfehérvár, Szekesfehervar

Bekes Megyei Kozponti Korhaz Pandy Kalman Tagkorhaz /ID# 252886, Gyula, Not set

Meir Medical Center /ID# 254187, Kfar Saba, HaMerkaz

Galilee Medical Center /ID# 252859, Nahariya, HaTsafon

The Chaim Sheba Medical Center /ID# 252857, Ramat Gan, Tel-Aviv

Tel Aviv Sourasky Medical Center /ID# 252858, Tel Aviv, Tel-Aviv

Hadassah Medical Center-Hebrew University /ID# 252654, Jerusalem, Yerushalayim

The Lady Davis Carmel Medical Center /ID# 253303, Haifa, Not set

Azienda Ospedaliera San Camillo Forlanini /ID# 253680, Rome, Roma

Azienda Ospedaliero-Universitaria Policlinico Umberto I /ID# 254288, Rome, Roma

Azienda Ospedaliero Universitaria delle Marche /ID# 254138, Ancona, Not set

Azienda Ospedale-Universita Padova /ID# 253704, Padova, Not set

Azienda Ospedaliero Universitaria Pisana /ID# 254289, Pisa, Not set

Hospital of the University of Occupational and Environmental Health, Japan /ID# 253269, Kitakyushu-shi, Fukuoka

Hokkaido University Hospital /ID# 253306, Sapporo-shi, Hokkaido

Tohoku University Hospital /ID# 253267, Sendai-shi, Miyagi

University of Miyazaki Hospital /ID# 253416, Miyazaki-shi, Miyazaki

Okayama University Hospital /ID# 253821, Okayama-shi, Okayama

Shinkenko Clinic /ID# 253271, Naha-shi, Okinawa

Saitama Medical Center /ID# 253263, Kawagoe, Saitama

Institute of Science Tokyo Hospital /ID# 254430, Bunkyo-ku, Tokyo

University of Yamanashi Hospital /ID# 253264, Chuo-shi, Yamanashi

National Hospital Org Chiba Medical Center Chibahigashi National Hospital /ID# 253268, Chiba, Not set

Hiroshima University Hospital /ID# 273658, Hiroshima, Not set

SoonChunHyang University Hospital Cheonan /ID# 254777, Cheonan-si, Chungcheongnamdo

Chonnam National University Bitgoeul Hospital /ID# 254675, Gwangju, Gwangju Gwang Yeogsi

Hanyang University Seoul Hospital /ID# 252955, Seoul, Seoul Teugbyeolsi

Asan Medical Center /ID# 254022, Seoul, Seoul Teugbyeolsi

The Catholic University of Korea, Seoul St. Marys Hospital /ID# 252958, Seoul, Seoul Teugbyeolsi

Riga East Clinical University Hospital /ID# 253751, Rīga, Riga

M & M Centrs LTD /ID# 253752, Adazi, Not set

Daugavpils Regional Hospital /ID# 253754, Daugavpils, Not set

Dr. Saulites-Kandevicas PP in Cardiology and Rheumatology /ID# 273246, Liepaja, Not set

Pauls Stradins Clinical University Hospital /ID# 253750, Riga, Not set

Hospital of Lithuanian University of Health Sciences Kaunas Clinics /ID# 253755, Kaunas, Not set

Republic Klaipeda Hospital /ID# 253759, Klaipeda, Not set

Klaipeda University Hospital, Klaipeda Hospital /ID# 253757, Klaipeda, Not set

Inlita - Santara KTC /ID# 253758, Vilnius, Not set

Vilnius University Hospital Santaros Klinikos /ID# 253756, Vilnius, Not set

Aotearoa Clinical Trials /ID# 253555, Papatoetoe, Auckland

North Shore Hospital /ID# 253554, Takapuna, Auckland

MICS Centrum Medyczne Bydgoszcz /ID# 253281, Bydgoszcz, Kujawsko-pomorskie

Szpital Uniwersytecki nr 2 im. dr. Jana Biziela /ID# 253233, Bydgoszcz, Kujawsko-pomorskie

MICS Centrum Medyczne Warszawa /ID# 253273, Warsaw, Mazowieckie

ETYKA-Osrodek Badan Klinicznych /ID# 252967, Olsztyn, Warminsko-mazurskie

Ortopedyczno-Rehabilitacyjny Szpital Kliniczny im. Wiktora Degi /ID# 252964, Poznan, Wielkopolskie

Centro Hospitalar do Tamega e Sousa - Hospital Padre Americo /ID# 252911, Guilhufe, Porto

Hospital Garcia de Orta /ID# 252903, Almada, Setubal

Unidade Local de Saúde do Alto Minho, EPE - Hospital Conde de Bertiandos /ID# 252902, Ponte de Lima, Viana Do Castelo

Centro Hospitalar Universitario do Porto, EPE - Hospital Santo Antonio /ID# 252899, Porto, Not set

Clinical Research Investigator Group, LLC /ID# 259170, Bayamon, Not set

Clinical Research Puerto Rico /ID# 256352, San Juan, Not set

GCM Medical Group PSC /ID# 253039, San Juan, Not set

Caribbean Medical Research Center /ID# 254882, San Juan, Not set

Mindful Medical Research /ID# 253040, San Juan, Not set

Spitalul Clinic Judetean de Urgenta Cluj -Napoca /ID# 252904, Cluj-Napoca, Cluj

Centrul Medical de Diagnostic si Tratament Ambulator Neomed SRL /ID# 253207, Brasov, Not set

Spitalul Clinic Sf. Maria /ID# 252905, Bucuresti, Not set

Institute for Rheumatology /ID# 253172, Belgrade, Beograd

Institute for Rheumatology /ID# 253173, Belgrade, Beograd

Institute for Rheumatology /ID# 253174, Belgrade, Beograd

Institute for Rheumatology /ID# 253175, Belgrade, Beograd

Military Medical Academy /ID# 264235, Belgrade, Beograd

Clin Hosp Ctr Bezanijska Kosa /ID# 253179, Belgrade, Beograd

General Hospital Djordje Joanovic /ID# 253177, Zrenjanin, Vojvodina

University Clinical Center Vojvodina /ID# 253176, Novi Sad, Not set

ARTROMAC n.o. /ID# 253056, Kosice, Kosicky Kraj

Narodny Ustav Reumatickych Chorob Piestany /ID# 273341, Piešťany, Trnavsky Kraj

MEDMAN s.r.o. /ID# 252950, Martin, Zilinsky Kraj

ZAZABIE s. r .o. /ID# 255793, Košice II, Not set

Thermium s.r.o. /ID# 260839, Piestany, Not set

Wits Clinical Research /ID# 252931, Johannesburg, Gauteng

University of Pretoria /ID# 252932, Pretoria, Gauteng

Dr Elsa van Duuren /ID# 254218, Pretoria, Gauteng

Dr Asokan Naidoo /ID# 253351, Umhlanga, Kwazulu-Natal

Winelands Medical Research - Somerset West /ID# 254614, Cape Town, Western Cape

Arthritis Clinical Research Trials /ID# 253349, Cape Town, Western Cape

Winelands Medical Research Centre /ID# 252934, Stellenbosch, Western Cape

Complejo Hospitalario Universitario A Coruña /ID# 253123, A Coruña, A Coruna

Hospital Meixoeiro (CHUVI) /ID# 253124, Vigo, Pontevedra

Hospital Universitario Virgen de Valme /ID# 253121, Sevilla, Not set

University Hospital Basel /ID# 252907, Basel Town, Basel-Stadt

Kantonsspital St. Gallen /ID# 252906, St. Gallen, Sankt Gallen

Inselspital, Universitaetsspital Bern /ID# 252909, Bern, Not set

National Taiwan University Hospital /ID# 252937, Taipei City, Taipei

Chang Gung Mem Hosp Keelung /ID# 253636, Keelung, Not set

China Medical University Hospital /ID# 252936, Taichung, Not set

Hacettepe Universitesi Tip Fak /ID# 253266, Sihhiye, Ankara, Ankara

Gazi Universitesi Tip Fakultes /ID# 252843, Yenimahalle, Ankara

Sanko Universitesi Hastanesi /ID# 252841, Şehitkamil, Gaziantep

Akdeniz Universitesi Tip Fakul /ID# 252839, Antalya, Not set

Basaksehir Cam ve Sakura Sehir Hastanesi /ID# 253557, Istanbul, Not set

Marmara Universitesi Pendik Egitim ve Arastirma Hastanesi /ID# 252844, Istanbul, Not set

Necmettin Erbakan Universitesi /ID# 252837, Meram Konya, Not set

Karadeniz Technical University Farabi Hospital /ID# 252845, Trabzon, Not set

North West Anglia NHS Foundation Trust /ID# 254590, Bretton, Cambridgeshire

Guy's Hospital /ID# 252978, London, Greater London

University Hospital Southampton NHS Foundation Trust /ID# 252982, Southampton, Hampshire

Northampton General Hospital NHS Trust /ID# 254813, Northampton, Northamptonshire

Western Health and Social Care Trust /ID# 254592, Londonderry, Northern Ireland

Luton and Dunstable Hospital NHS Foundation Trust /ID# 255323, Luton, Not set

Portsmouth Hospitals University NHS Trust /ID# 252986, Portsmouth, Not set

Conditions: Systemic Lupus Erythematosus

Learn More ›

A Study of CC-97540, CD-19-Targeted Nex-T CAR T Cells, in Participants With Severe, Refractory Autoimmune Diseases (Breakfree-1)

NCT05869955

Recruiting

The purpose of this study is to establish the tolerability, preliminary efficacy, and pharmacokinetics of CC-97540 in participants with severe, refractory autoimmune diseases (Breakfree-1).

Gender:

ALL

Ages:

18 years and above

Trial Updated:

08/08/2025

Locations: University of Colorado Anschutz Medical Campus, Aurora, Colorado +53 locations

University of Colorado Anschutz Medical Campus, Aurora, Colorado

Colorado Blood Cancer Institute, Denver, Colorado

Local Institution - 0048, New Haven, Connecticut

Mayo Clinic in Florida, Jacksonville, Florida

University of Miami Hospital and Clinics, Sylvester Cancer Center, Miami, Florida

Local Institution - 0053, Chicago, Illinois

Local Institution - 0030, Baltimore, Maryland

Local Institution - 0038, Boston, Massachusetts

Local Institution - 0046, Boston, Massachusetts

University of Massachusetts Chan Medical School, Worcester, Massachusetts

University of Michigan, Ann Arbor, Michigan

Henry Ford Medical Center - New Center One, Detroit, Michigan

Mayo Clinic in Rochester, Minnesota, Rochester, Minnesota

Washington University School of Medicine, Saint Louis, Missouri

University Of Nebraska Medical Center, Omaha, Nebraska

Atlantic Health System Overlook Medical Center, Summit, New Jersey

NYU Langone Health, New York, New York

Local Institution - 0054, New York, New York

Icahn School of Medicine at Mount Sinai, New York, New York

Columbia University Irving Medical Center, New York, New York

Local Institution - 0055, New York, New York

The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina

Cleveland Clinic, Cleveland, Ohio

Local Institution - 0027, Columbus, Ohio

UT Southwestern Medical Center, Dallas, Texas

The University of Texas Health Science Center at Houston, Houston, Texas

University of Texas MD Anderson Cancer Center, Houston, Texas

Swedish Medical Center, Seattle, Washington

Local Institution - 0057, Seattle, Washington

Fred Hutchinson Cancer Center, Seattle, Washington

UZ Leuven, Leuven, Vlaams-Brabant

Local Institution - 0043, Strasbourg, Alsace

CHU Bordeaux Haut-Leveque, Pessac, Aquitaine

CHU Montpellier Lapeyronie Hospital, Montpellier, Hérault

Hopital Claude Huriez - CHU de Lille, Lille, Not set

Centre Hospitalier Universitaire de Nice - Hôpital l'Archet, Nice, Not set

Hôpital Saint-Louis, Paris, Not set

Local Institution - 0052, Paris, Not set

Centre Hospitalier Universitaire de Rennes - Hôpital Pontchaillou, Rennes, Not set

Universitaetsklinikum Wuerzburg, Wuerzburg, Bayern

Universitaetsklinikum Koeln, Köln, Nordrhein-Westfalen

Otto-von-Guericke-Universität Magdeburg, Magdeburg, Sachsen-Anhalt

Universitätsklinikum Leipzig, Leipzig, Sachsen

Charité Universitaetsmedizin Berlin - Campus Mitte, Berlin, Not set

Universitaetsklinikum Duesseldorf, Düsseldorf, Not set

Universitaetsklinikum Erlangen, Erlangen, Not set

Fondazione Policlinico Universitario Agostino Gemelli IRCCS - Università Cattolica del Sacro Cuore, Roma, Lazio

Humanitas, Rozzano, Milano

Hospital Universitari Vall d'Hebron, Barcelona, Barcelona [Barcelona]

Hospital Universitario Marqués de Valdecilla, Santander, Cantabria

Hospital Clínic de Barcelona, Barcelona, Catalunya [Cataluña]

Hospital Universitario Reina Sofia, Cordoba, Not set

H.R.U Málaga - Hospital General, Málaga, Not set

Conditions: Systemic Lupus Erythematosus, Idiopathic Inflammatory Myopathy, Systemic Sclerosis, Rheumatoid Arthritis

Learn More ›

A Study to Evaluate the Efficacy and Safety of Dapirolizumab Pegol in Study Participants With Moderately to Severely Active Systemic Lupus Erythematosus

NCT06617325

Recruiting

The purpose of this study is to evaluate the ability of dapirolizumab pegol (DZP) as an add-on treatment to standard of care (SOC) medication to achieve clinically relevant long term improvement of moderate to severe disease activity.

Gender:

ALL

Ages:

16 years and above

Trial Updated:

08/07/2025

Locations: Sl0044 50058, Avondale, Arizona +158 locations

Sl0044 50058, Avondale, Arizona

Sl0044 50550, Chandler, Arizona

Sl0044 50713, Gilbert, Arizona

Sl0044 50662, Glendale, Arizona

Sl0044 50052, Phoenix, Arizona

Sl0044 50670, Searcy, Arkansas

Sl0044 50257, La Jolla, California

Sl0044 50275, La Palma, California

Sl0044 50258, Los Angeles, California

Sl0044 50725, Menifee, California

Sl0044 50340, Orange, California

Sl0044 50630, Clearwater, Florida

Sl0044 50681, Miami, Florida

Sl0044 50324, Plantation, Florida

Sl0044 50698, Tampa, Florida

Sl0044 50585, Winter Park, Florida

Sl0044 50566, Gainesville, Georgia

Sl0044 50659, Marietta, Georgia

Sl0044 50699, Chicago, Illinois

Sl0044 50717, Willowbrook, Illinois

Sl0044 50285, Lake Charles, Louisiana

Sl0044 50660, New Orleans, Louisiana

Sl0044 50219, Detroit, Michigan

Sl0044 50682, Kansas City, Missouri

Sl0044 50010, Brooklyn, New York

Sl0044 50264, Manhasset, New York

Sl0044 50077, New York, New York

Sl0044 50238, Charlotte, North Carolina

Sl0044 50001, Jackson, Tennessee

Sl0044 50693, Murfreesboro, Tennessee

Sl0044 50562, Allen, Texas

Sl0044 50316, Colleyville, Texas

Sl0044 50673, Fort Worth, Texas

Sl0044 50688, Houston, Texas

Sl0044 50696, Houston, Texas

Sl0044 50718, Mansfield, Texas

Sl0044 50036, Mesquite, Texas

Sl0044 50061, Spokane, Washington

Sl0044 60004, C.a.b.a, Not set

Sl0044 60002, Capital Federal, Not set

Sl0044 60029, Mendoza, Not set

Sl0044 60003, Quilmes, Not set

Sl0044 60011, San Juan, Not set

Sl0044 60014, Tucuman, Not set

Sl0044 40002, Leuven, Not set

Sl0044 20293, Baotou, Not set

Sl0044 20128, Beijing, Not set

Sl0044 20157, Beijing, Not set

Sl0044 20173, Beijing, Not set

Sl0044 20201, Bengbu, Not set

Sl0044 20186, Chang ZHOU, Not set

Sl0044 20291, Changchun, Not set

Sl0044 20295, Changsha, Not set

Sl0044 20019, Guangzhou, Not set

Sl0044 20290, Guilin, Not set

Sl0044 20271, Haikou, Not set

Sl0044 20296, Hangzhou, Not set

Sl0044 20185, Jinan, Not set

Sl0044 20192, Nanchang, Not set

Sl0044 20024, Nanjing, Not set

Sl0044 20272, Pingxiang, Not set

Sl0044 20020, Shanghai, Not set

Sl0044 20172, Shanghai, Not set

Sl0044 20346, Shantou, Not set

Sl0044 20204, Suzhou, Not set

Sl0044 20136, Tianjin, Not set

Sl0044 20275, Urumuqi, Not set

Sl0044 20025, Wenzhou, Not set

Sl0044 20180, Wuhan, Not set

Sl0044 20270, Wuhan, Not set

Sl0044 20274, Xi'an, Not set

Sl0044 20273, Yangzhou, Not set

Sl0044 20132, Zhengzhou, Not set

Sl0044 40513, Copenhagen, Not set

Sl0044 40489, Odense, Not set

Sl0044 40848, Le Mans, Not set

Sl0044 40506, Montpellier, Not set

Sl0044 40322, DESSAU-ROßLAU, Not set

Sl0044 40356, Dresden, Not set

Sl0044 40072, Freiburg, Not set

Sl0044 40717, Greifswald, Not set

Sl0044 40027, Herne, Not set

Sl0044 40139, Jena, Not set

Sl0044 40386, Koeln, Not set

Sl0044 40716, Köln, Not set

Sl0044 40078, Leipzig, Not set

Sl0044 40815, Muenchen, Not set

Sl0044 40402, Tübingen, Not set

Sl0044 40715, Vogelsang-gommern, Not set

Sl0044 40376, Athens, Not set

Sl0044 40501, Athens, Not set

Sl0044 40377, Heraklion, Not set

Sl0044 40507, Larissa, Not set

Sl0044 40816, Brescia, Not set

Sl0044 40514, Genova, Not set

Sl0044 40291, Milano, Not set

Sl0044 40471, Milano, Not set

Sl0044 40509, Padova, Not set

Sl0044 40176, Pisa, Not set

Sl0044 40148, Roma, Not set

Sl0044 20035, Bunkyo-ku, Not set

Sl0044 20196, Bunkyo-ku, Not set

Sl0044 20279, Bunkyo-ku, Not set

Sl0044 20030, Chuo-ku, Not set

Sl0044 20281, Fukuoka, Not set

Sl0044 20282, Fukuoka, Not set

Sl0044 20039, Kawagoe, Not set

Sl0044 20045, Kita-gun, Not set

Sl0044 20065, Kitakyushu, Not set

Sl0044 20301, Kurashiki, Not set

Sl0044 20069, Meguro-ku, Not set

Sl0044 20071, Nagasaki, Not set

Sl0044 20287, Nagoya, Not set

Sl0044 20283, Sagamihara, Not set

Sl0044 20084, Saga, Not set

Sl0044 20031, Sapporo, Not set

Sl0044 20042, Sasebo, Not set

Sl0044 20171, Sendai-shi, Not set

Sl0044 20076, Shinjuku-ku, Not set

Sl0044 20285, Shinjuku-ku, Not set

Sl0044 20032, Suita, Not set

Sl0044 20277, Suita, Not set

Sl0044 20278, TSU, Not set

Sl0044 20276, Yoshida-gun, Not set

Sl0044 20141, Busan, Not set

Sl0044 20104, Seoul, Not set

Sl0044 20092, Suwon-si, Not set

Sl0044 40838, Amsterdam, Not set

Sl0044 60026, Arequipa, Not set

Sl0044 60009, Surco, Not set

Sl0044 40398, Katowice, Not set

Sl0044 40795, Katowice, Not set

Sl0044 40502, Krakow, Not set

Sl0044 40037, Lublin, Not set

Sl0044 40044, Poznan, Not set

Sl0044 40821, Poznan, Not set

Sl0044 40097, Warszawa, Not set

Sl0044 40098, Warszawa, Not set

Sl0044 40481, Wroclaw, Not set

Sl0044 50671, Caguas, Not set

Sl0044 50683, San Juan, Not set

Sl0044 40466, Kragujevac, Not set

Sl0044 40392, Novi Sad, Not set

Sl0044 40045, A Coruna, Not set

Sl0044 40826, Badajoz, Not set

Sl0044 40159, Barcelona, Not set

Sl0044 40160, Barcelona, Not set

Sl0044 40839, Castelló de La Plana, Not set

Sl0044 40341, Málaga, Not set

Sl0044 40521, Mérida, Not set

Sl0044 40101, Sabadell, Not set

Sl0044 40049, Sevilla, Not set

Sl0044 40103, Sevilla, Not set

Sl0044 20330, New Taipei City, Not set

Sl0044 20142, Taichung City, Not set

Sl0044 20080, Taichung, Not set

Sl0044 20086, Taipei City, Not set

Sl0044 20099, Taipei City, Not set

Sl0044 20082, Taiyuan CITY, Not set

Conditions: Systemic Lupus Erythematosus

Learn More ›

A Study to Assess Effectiveness and Safety of Deucravacitinib Compared With Placebo in Participants With Active Systemic Lupus Erythematosus (SLE)

NCT05617677

Recruiting

The purpose of this study is to evaluate the effectiveness and safety of deucravacitinib compared with placebo in an active moderate to severe Systemic Lupus Erythematosus (SLE) population.

Gender:

ALL

Ages:

Between 18 years and 75 years

Trial Updated:

08/07/2025

Locations: University of Alabama at Birmingham, Birmingham, Alabama +221 locations

University of Alabama at Birmingham, Birmingham, Alabama

Local Institution - 0229, Phoenix, Arizona

Local Institution - 0230, Phoenix, Arizona

The University of Arizona Arthritis Center, Tucson, Arizona

Kaiser Permanente, Fontana, California

Private Practice - Dr. Chandrakant V. Mehta, Hemet, California

Local Institution - 0247, La Mesa, California

Arthritis & Osteoporosis Medical Center - La Palma, La Palma, California

UCLA Clinical & Translational Research Center (CTRC), Los Angeles, California

Local Institution - 0248, Sacramento, California

Local Institution - 0253, San Diego, California

Local Institution - 0128, Santa Barbara, California

Local Institution - 0099, Denver, Colorado

Yale New Haven Hospital-Smilow Cancer Center, New Haven, Connecticut

Rheumatology Assoc. Of South Florida, Boca Raton, Florida

Local Institution - 0249, Coral Springs, Florida

Nouvelle Clinical Research, Cutler Bay, Florida

University of Florida College of Medicine, Gainesville, Florida

University of Miami Hospital and Clinics, Sylvester Cancer Center, Miami, Florida

Omega Research Group - Orlando, Orlando, Florida

Discovery Health Research, Plantation, Florida

West Broward Rheumatology Associates, Tamarac, Florida

Genesis Clinical Research, LLC, Tampa, Florida

Local Institution - 0165, Tampa, Florida

Piedmont West, Atlanta, Georgia

Local Institution - 0228, Lawrenceville, Georgia

Local Institution - 0234, Lawrenceville, Georgia

North Georgia Rheumatology, Lawrenceville, Georgia

IBJI Morton Grove, Morton Grove, Illinois

Greater Chicago Specialty Physicians, Schaumburg, Illinois

Local Institution - 0108, Indianapolis, Indiana

Lake Cumberland Rheumatology, New Albany, Indiana

Ochsner Clinic Foundation, New Orleans, Louisiana

Local Institution - 0006, Detroit, Michigan

Saint Paul Rheumatology, Eagan, Minnesota

Atlantic Health System Overlook Medical Center, Summit, New Jersey

Local Institution - 0159, Bronx, New York

The Feinstein Institute for Medical Research, Manhasset, New York

NYU Langone Health, New York, New York

University of Rochester Medical Center, Rochester, New York

Arthritis and Osteoporosis Consultants of the Carolinas, Charlotte, North Carolina

Carolinas HealthCare System SouthPark, Charlotte, North Carolina

Local Institution - 0246, Summerville, South Carolina

Local Institution - 0003, Memphis, Tennessee

Arthritis and Rheumatology Research Institute, Allen, Texas

UT Southwestern Medical Center, Dallas, Texas

Local Institution - 0088, Fort Worth, Texas

Local Institution - 0250, Houston, Texas

Local Institution - 0219, Lubbock, Texas

Advanced Rheumatology of Houston - Woodlands, The Woodlands, Texas

Carilion Clinic, Roanoke, Virginia

Swedish Medical Center, Seattle, Washington

Local Institution - 0139, Seattle, Washington

Local Institution - 0063, Franklin, Wisconsin

Instituto De Investigaciones Clinicas Quilmes, Quilmes, Buenos Aires

Fundacion Cidea, Buenos Aires, Ciudad Autónoma De Buenos Aires

APRILLUS Asistencia e Investigacion Clinica, Caba, Ciudad Autónoma De Buenos Aires

Investigaciones Clínicas Tucumán, San Miguel de Tucuman, Tucumán

Private Practice - Dr. Javier Gerardo Tartaglione, Buenos Aires, Not set

Hospital Británico de Buenos Aires, Buenos Aires, Not set

Stat Research S.A., Ciudad Autónoma de Buenos Aires, Not set

Hospital J. M. Ramos Mejía, Ciudad Autónoma de Buenos Aires, Not set

Hospital Córdoba, Córdoba, Not set

Instituto de Reumatología, Mendoza, Not set

Serviços Especializados em Reumatologia, Salvador, Bahia

Hospital Brasilia, Lago sul, Distrito Federal

Santa Casa de Misericordia de Belo Horizonte, Belo Horizonte, Minas Gerais

Cmip-Centro Mineiro de Pesquisa, Juiz de Fora, Minas Gerais

Hospital Universitário Evangélico Mackenzie, Curitiba, Paraná

Local Institution - 0075, Niteroi, Rio De Janeiro

Hospital São Lucas da PUCRS, Porto Alegre, Rio Grande Do Sul

Clinica Medica Bonfiglioli, Campinas, São Paulo

Hospital das Clínicas da Faculdade de Medicina de Ribeirão Preto da Universidade de São Paulo (USP) - HCFMRP, Ribeirão Preto, São Paulo

Hospital do Rim e Hipertensão, Sao Paulo, São Paulo

Fundação Faculdade Regional de Medicina de São José do Rio Preto, São José do Rio Preto, São Paulo

Hospital Universitário Pedro Ernesto, Rio de Janeiro, Not set

Hospital das Clinicas FMUSP, São Paulo, Not set

Local Institution - 0048, São Paulo, Not set

Medical Center Artmed, Plovdiv, Not set

MC Excelsior, Sofia, Not set

ACIBADEM City Clinic Diagnostic-Consultative Center, Sofia, Not set

University of Calgary, Cumming School of Medicine, Calgary, Alberta

Local Institution - 0160, Hamilton, Ontario

St. Joseph's Health Care, London, Ontario

Toronto Western Hospital, Toronto, Ontario

Centre intégré de santé et de services sociaux du Bas Saint-Laurent- Hôpital régional de Rimouski, Rimouski, Quebec

The First Afflilated Hospital of Bengbu Medical College, Bengbu, Anhui

Beijing Peking Union Medical College Hospital, Beijing, Beijing

The First Affiliated hospital of Xiamen University, Xiamen, Fujian

Guangdong Provincial People's Hospital, Guangzhou, Guangdong

The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, Guangdong

Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou, Guangdong

ShenZhen People's Hospital, Shenzhen, Guangdong

Local Institution - 0153, Baoding, Hebei

The First Affiliated Hospital of Henan University of Science &Technology, Luoyang, Henan

The First Affiliated Hospital of Zhengzhou Universtiy, Zhengzhou, Henan

Union Hospital Tongji Medical College Huazhong University of Science and Technology, Wuhan, Hubei

Xiangya Hospital Central South University, Changsha, Hunan

ZhuZhou Central Hospital, Zhuzhou, Hunan

Local Institution - 0059, Baotou, Inner Mongolia

The Affiliated Hospital of Inner Mongolia Medical University, Hohhot, Inner Mongolia

The First People's Hospital of Changzhou, Changzhou, Jiangsu

Jiu Jiang No.1 People's Hospital, Jiujiang, Jiangxi

Local Institution - 0071, Nanchang, Jiangxi

The First Affiliated Hospital of Nanchang University, Nanchang, Jiangxi

The Second Affiliated Hospital of Nanchang University, Nanchang, Jiangxi

Pingxiang People's Hospital, Pingxiang, Jiangxi

The First Hospital of China Medical University, Shenyang, Liaoning

Shengjing Hospital of China Medical University, Shenyang, Liaoning

Local Institution - 0149, Jinan, Shandong

Ruijin Hospital Shanghai Jiaotong University School of Medicine, Shanghai, Shanghai

Huashan Hospital, Fudan University, Shanghai, Shanghai

Renji Hospital Shanghai Jiao Tong University School of Medicine, Shanghai, Shanghai

West China Hospital, Sichuan University, Cheng Du, Sichuan

Local Institution - 0053, Tianjin, Tianjin

People's Hospital of Xinjiang Uygur Autonomous Region, Urumqi, Xinjiang

The first Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang

Wenzhou People's Hospital, Wenzhou, Zhejiang

Shanxi Bethune Hospital, Taiyuan, Not set

Salud SURA Industriales, Medellín, Antioquia

Centro Integral de Reumatología del Caribe, Barranquilla, Atlántico

Servimed EU, Bucaramanga, Santander

Hospital Universitario San Ignacio, Bogota, Not set

Cireem Sas, Bogotá, Not set

IPS Centro Médico Julián Coronel S.A.S, Cali, Not set

Local Institution - 0058, Cali, Not set

Preventive Care, Chia, Not set

Local Institution - 0055, Medellin, Not set

Nouvel Hôpital Civil (NHC), Strasbourg, Alsace

Centre Hospitalier Universitaire de Nantes - L' Hopital l'hôtel-Dieu, Nantes, Loire-Atlantique

Hôpitaux Universitaires Paris Sud - Hôpital Bicêtre, Le Kremlin-Bicêtre, Not set

Local Institution - 0156, Tours, Not set

Universitaetsklinikum Tuebingen, Tübingen, Baden-Württemberg

Klinikum der Ludwig-Maximilians-Universitaet Muenchen, Muenchen, Bayern

Universitaetsklinikum Carl Gustav Carus Dresden, Dresden, Sachsen

Universitätsklinikum Schleswig-Holstein, Lübeck, Schleswig-Holstein

DRK-Krankenhaus Rabenstein, Chemnitz, Not set

Universitaetsklinikum Erlangen, Erlangen, Not set

Universitaetsklinikum Koeln, Köln, Not set

Klinische Forschung im medizinischen Versorgungalltag GbR, Planegg, Not set

Tuen Mun Hospital, Tuen Mun, Not set

Local Institution - 0213, Vizianagaram, Andhra Pradesh

Amber Clinic, Ahmedabad, Gujarat

Local Institution - 0243, Surat, Gujarat

Medanta The Medicity, Gurugram, Haryana

ChanRe Rheumatology And Immunology Center And Research, Bengaluru, Karnataka

ESIC Medical College, Hyderabad, Telangana

Nizam's Institute of Medical Sciences, Hyderabad, Telangana

Local Institution - 0119, Manorhamilton, Leitrim

Local Institution - 0130, Cork, Not set

Local Institution - 0157, Dublin, Not set

Local Institution - 0172, Dublin, Not set

AOU Policlinico Umberto I, Roma, Lazio

Centro Specialistico Ortopedico Traumatologico Gaetano Pini - CTO, Milano, Lombardia

Azienda Ospedaliera Universitaria Pisana, Pisa, Toscana

Azienda Ospedale - Università Padova, Padova, Veneto

Azienda Ospedaliera Spedali Civili di Brescia, Brescia, Not set

Ospedale San Raffaele, Milano, Not set

AOU della Campania Luigi Vanvitelli, Napoli, Not set

Local Institution - 0118, Pavia, Not set

Azienda Ospedaliera Universitaria Integrata Verona - Ospedale Borgo Roma, Verona, Not set

Chonnam National University Hospital, Gwangju-si, Kwangju-Kwangyǒkshi

Ajou University Hospital, Suwon, Kyǒnggi-do

The Catholic Univ. of Korea Seoul St. Mary's Hospital, Seoul, Seoul-teukbyeolsi [Seoul]

Local Institution - 0105, Jung-gu, Taegu-Kwangyǒkshi

Local Institution - 0106, Jung-gu, Taejǒn-Kwangyǒkshi

Hanyang University Seoul Hospital, Seoul, Not set

Hospital of Lithuanian University of Health Sciences Kauno klinikos, Kaunas, Kauno Apskritis

Centro Medico del Angel, Mexicali, Baja California

Boca Clinical Trials Mexico SC, Ciudad de México, Distrito Federal

Local Institution - 0027, Mexico City, Distrito Federal

Instituto para el DeSarrollo Integral de la Salud S de RL de CV, Mexico City, Distrito Federal

Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran, Mexico City, Distrito Federal

Clinstile, S.A. de C.V., Mexico, Distrito Federal

Hospital Aranda de La Parra, Leon, Guanajuato

Local Institution - 0024, Zapopan, Jalisco

Investigacion y Biomedicina de Chihuahua, Chihuahua, Not set

Local Institution - 0014, Mexico City, Not set

Boca Clinical Trials Mexico SC, Puebla, Not set

Local Institution - 0237, Chisinau, Chișinău

Local Institution - 0238, Chisinau, Chișinău

Republican Clinical Hospital, Chisinau, Not set

Hogar Clínica San Juan de Dios, Arequipa, Not set

Instituto Peruano del Hueso y la Articulación, Lima, Not set

Centro Medico CORPAC, Lima, Not set

Investigaciones Clínicas / Instituto de Ginecología y Reproducción, Lima, Not set

Local Institution - 0196, Wroclaw, Dolnośląskie

Szpital Uniwersytecki Nr 2 im. dr J. Biziela w Bydgoszczy, Bydgoszcz, Kujawsko-pomorskie

Local Institution - 0244, Lublin, Lubelskie

Mak-Med Clinic Sp. Z O.O., Nadarzyn, Mazowieckie

Narodowy Instytut Geriatrii, Reumatologii i Rehabilitacji, Warsaw, Mazowieckie

Rheuma Medicus Sp. z o.o., Warszawa, Mazowieckie

Local Institution - 0194, Wolomin, Mazowieckie

Centrum Medyczne Plejady, Krakow, Małopolskie

Medyczne Centrum Hetmańska, Poznan, Wielkopolskie

Local Institution - 0030, Poznań, Wielkopolskie

Nova Reuma Społka Partnerska, Bialystok, Not set

Synexus Polska Sp. z o.o. Oddzial w Poznaniu, Poznan, Not set

Local Institution - 0211, Belchatow, Łódzkie

Centrum Medyczne Pratia Katowice, Katowice, Śląskie

Local Institution - 0073, Lisbon, Not set

Centro Reumatologico Caguas, Caguas, Not set

Local Institution - 0252, San Juan, Not set

GCM Medical Group, PSC - Hato Rey Site, San Juan, Not set

Hiperdia Piața Sudului, Bucharest, Bucureşti

Hightech Medical Services SRL-Centrul pentru Studiul Metabolismului, Bucharest, București

Spital Clinic Sf. Maria, Bucharest, București

Delta Health Care, Bucharest, București

Spitalul Clinic Colentina, Bucuresti, București

CCBR Clinical Research, Bucuresti, București

Medisof Diagnostic SR, Craiova, Dolj

RK Medcenter, Iasi, Iași

Sc Medaudio-Optica Srl, Râmnicu Vâlcea, Vâlcea

Private Practice - Dr. Carina Anna Triff, Timisoara, Not set

Local Institution - 0207, Svidnik, Prešovský Kraj

Local Institution - 0206, Martin, Žilinský Kraj

Local Institution - 0232, Pretoria, GP

Local Institution - 0233, Cape Town, Western Cape

Local Institution - 0231, Stellenbosch, Western Cape

Gazi University Health Research and Application Center Gazi Hospital, Ankara, Not set

Istanbul University Cerrahpasa Medical School Internal Diseases Institute, Istanbul, Not set

Kocaeli Üniversitesi, Kocaeli, Not set

Conditions: Systemic Lupus Erythematosus

Learn More ›

Efficacy and Safety of Frexalimab (SAR441344) in the Treatment of Systemic Lupus Erythematosus

NCT05039840

Recruiting

This is a multinational, randomized, placebo-controlled, parallel treatment, Phase 2, double-blind, 2 arm study evaluating the efficacy and safety of SAR441344 in comparison with placebo in the treatment of participants aged 18 to 70 years with active Systemic Lupus Erythematosus (SLE). Study details include: * Study duration: 36 weeks * Treatment duration: 24 weeks * Visit frequency: every 2 weeks

Gender:

ALL

Ages:

Between 18 years and 70 years

Trial Updated:

08/07/2025

Locations: Accel Resarch Sites- Site Number : 8400003, Birmingham, Alabama +69 locations

Accel Resarch Sites- Site Number : 8400003, Birmingham, Alabama

AARA Clinical Research - Arizona Arthritis & Rheumatology Associates - Chandler- Site Number : 8400026, Chandler, Arizona

Arizona Arthritis & Rheumatology Associates - South Vineyard Avenue- Site Number : 8400022, Mesa, Arizona

Arizona Arthritis & Rheumatology Research - Sun City- Site Number : 8400027, Sun City, Arizona

AARA Clinical Research - Arizona Arthritis & Rheumatology Associates - Tucson Southeast- Site Number : 8400023, Tucson, Arizona

Saint John's Physician Partners- Site Number : 8400015, Santa Monica, California

Millennium Clinical Trials - Simi Valley- Site Number : 8400004, Simi Valley, California

Omega Research Consultants - Debary - North Charles Richard Beall Boulevard- Site Number : 8400002, DeBary, Florida

Integral Rheumatology and Immunology Specialists- Site Number : 8400014, Plantation, Florida

Infigo Clinical Research- Site Number : 8400016, Sanford, Florida

Inspire Santa Fe Medical Group- Site Number : 8400019, Santa Fe, New Mexico

Columbia University Medical Center - New York- Site Number : 8400009, New York, New York

RAO - Rheumatology Associates of Oklahoma- Site Number : 8400013, Oklahoma City, Oklahoma

Private Practice - Dr. Ramesh C. Gupta I- Site Number : 8400008, Memphis, Tennessee

Tekton Research - West Gate- Site Number : 8400001, Austin, Texas

Precision Comprehensive Clinical Research Solutions - Colleyville- Site Number : 8400017, Colleyville, Texas

Lone Start Arthritis & Rheumatology Associates- Site Number : 8400025, Fort Worth, Texas

Prolato Clinical Research Center- Site Number : 8400005, Houston, Texas

AARA Clinical Research Lone Star Arthritis and Rheumatology- Site Number : 8400024, Irving, Texas

West Texas Clinical Research- Site Number : 8400018, Lubbock, Texas

Investigational Site Number : 0320008, Berazategui, Buenos Aires

Investigational Site Number : 0320003, San Miguel de Tucumán, Tucumán

Investigational Site Number : 0320006, Buenos Aires, Not set

Investigational Site Number : 0320001, Buenos Aires, Not set

Investigational Site Number : 0320004, Buenos Aires, Not set

Investigational Site Number : 0320002, Buenos Aires, Not set

Centro de Estudos em Terapias Inovadoras- Site Number : 0760002, Curitiba, Paraná

LMK Servicos Medicos- Site Number : 0760001, Porto Alegre, Rio Grande Do Sul

Fundação Faculdade Regional de Medicina de São José do Rio Preto- Site Number : 0760006, São José Do Rio Preto, São Paulo

IBCC - Núcleo de Pesquisa e Ensino- Site Number : 0760007, São Paulo, Not set

Centro Paulista de Investigaçăo Clínica - CEPIC- Site Number : 0760004, São Paulo, Not set

Investigational Site Number : 1520002, Osorno, Los Lagos

Investigational Site Number : 1520003, Talca, Maule

Investigational Site Number : 1520004, Santiago, Reg Metropolitana De Santiago

Investigational Site Number : 1520001, Santiago, Reg Metropolitana De Santiago

Investigational Site Number : 2680004, Tbilisi, Not set

Investigational Site Number : 2680001, Tbilisi, Not set

Investigational Site Number : 2680003, Tbilisi, Not set

Investigational Site Number : 2680002, Tbilisi, Not set

Investigational Site Number : 3000004, Athens, Not set

Investigational Site Number : 3000001, Athens, Not set

Investigational Site Number : 3000003, Heraklion, Not set

Investigational Site Number : 3000005, Larissa, Not set

Investigational Site Number : 3000002, Thessaloniki, Not set

Investigational Site Number : 3480002, Gyula, Not set

Investigational Site Number : 3480003, Székesfehérvár, Not set

IRCCS Ospedale San Raffaele-Site Number : 3800001, Milan, Milano

Investigational Site Number: 3800004, Naples, Napoli

Fondazione Policlinico Universitario Agostino Gemelli-Site Number : 3800002, Roma, Not set

Investigational Site Number : 4800001, Vacoas-phoenix, Not set

Investigational Site Number : 4840009, Mexico City, Ciudad De Mexico

Investigational Site Number : 4840004, Mexico City, Ciudad De Mexico

Investigational Site Number : 4840001, Monterrey, Nuevo León

Investigational Site Number : 4840005, Mérida, Yucatán

Investigational Site Number : 4840006, Chihuahua, Not set

Investigational Site Number : 4840011, Chihuahua, Not set

Investigational Site Number : 4840007, Mexico City, Not set

Investigational Site Number : 4840008, Veracruz, Not set

GCM Medical Group - San Juan - Calle Jose Marti- Site Number : 8400011, San Juan, Not set

Investigational Site Number : 6430002, Moscow, Not set

Investigational Site Number : 7240002, Sabadell, Castilla Y León

Investigational Site Number : 7240001, Madrid, Not set

Investigational Site Number : 7240005, Valencia, Not set

Investigational Site Number : 7240004, Valladolid, Not set

Investigational Site Number : 7560001, St. Gallen, Not set

Investigational Site Number : 7920003, Ankara, Not set

Investigational Site Number : 7920002, Denizli, Not set

Investigational Site Number : 8040006, Kyiv, Not set

Investigational Site Number : 8040001, Kyiv, Not set

Investigational Site Number : 8040005, Poltava, Not set

Conditions: Systemic Lupus Erythematosus

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A Phase 2a Master Protocol Assessing Inebilizumab and Blinatumomab in Autoimmune Diseases

NCT06570798

Recruiting

The main objective is to assess the safety and tolerability of inebilizumab in adult participants with active and refractory systemic lupus erythematosus (SLE) with nephritis (Subprotocol A) and to assess the safety and tolerability of subcutaneous (SC) blinatumomab in adult participants with active and refractory SLE with nephritis (Subprotocol B) and in adult participants with active refractory rheumatoid arthritis (RA) (Subprotocol C).

Gender:

ALL

Ages:

Between 18 years and 75 years

Trial Updated:

08/06/2025

Locations: HonorHealth Research and Innovation Institute, Scottsdale, Arizona +38 locations

HonorHealth Research and Innovation Institute, Scottsdale, Arizona

University of Colorado, Aurora, Colorado

Vida Research Center, Hialeah, Florida

Homestead Associates In Research Inc, Homestead, Florida

Vitaly Clinical Research, Miami, Florida

Northwell Health, Great Neck, New York

MetroHealth Medical Center, Cleveland, Ohio

Prolato Clinical Research Center, Houston, Texas

Cliniques Universtaire Saint Luc Universite Catholique de Louvain, Bruxelles, Not set

Universitair Ziekenhuis Gent, Gent, Not set

Centre Hospitalier Universitaire de Liege - Sart Tilman, Liege, Not set

Hôpitaux Universitaires Paris Sud - Hôpital Bicêtre, Le Kremlin Bicetre, Not set

Centre Hospitalier Regional Universitaire de Lille - Hopital Claude Huriez, Lille cedex 01, Not set

Centre Hospitalier Universitaire de Lyon- Hopital Edouard Herriot, Lyon Cedex 03, Not set

Centre Hospitalier Universitaire de Lyon - Hopital Edouard Herriot, Lyon Cédex 3, Not set

Hopital de la Conception, Marseille, Not set

Hopital Europeen Georges Pompidou, Paris cedex 15, Not set

Hopital Cochin, Paris, Not set

Hopital Bichat Claude Bernard, Paris, Not set

Centre Hospitalier Universitaire de Strasbourg - Hopital de Hautepierre, Strasbourg Cedex, Not set

Centre Hospitalier Universitaire de Strasbourg - Nouvel Hopital Civil, Strasbourg, Not set

Centre Hospitalier Universitaire de Toulouse - Hopital Purpan, Toulouse Cedex 9, Not set

Centre Hospitalier Universitaire de Toulouse - Hopital Rangueil, Toulouse Cedex 9, Not set

Universitaetsklinikum Duesseldorf AoeR, Duesseldorf, Not set

Universitaetsklinikum Leipzig, Leipzig, Not set

Klinikum der LMU Muenchen, Muenchen, Not set

IRCCS Ospedale San Raffaele, Milano, Not set

IRCCS Istituto Clinico Humanitas, Rozzano, Not set

Ospedale San Giovanni Bosco, Torino, Not set

Unidade Local de Saude de Lisboa Ocidental, EPE - Hospital Santa Cruz, Carnaxide, Not set

Unidade Local de Saude de Sao Jose, EPE - Hospital Curry Cabral, Vila Franca de Xira, Not set

Unidade Local de Saude de Gaia-Espinho, EPE, Vila Nova de Gaia, Not set

Hospital Universitario Marques de Valdecilla, Santander, Cantabria

Hospital Universitari Vall d Hebron, Barcelona, Cataluña

Hospital Clinic i Provincial de Barcelona, Barcelona, Cataluña

Hospital Universitari Vall d Hebron, Barcelona, Not set

Hospital Universitario 12 de Octubre, Madrid, Not set

Addenbrookes Hospital, Cambridge, Not set

Royal Victoria Infirmary, Newcastle Upon Tyne, Not set

Conditions: Systemic Lupus Erythematosus, Active Refractory Rheumatoid Arthritis

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UC-MSC Cell Therapy Study for Systemic Lupus Erythematosus (SLE) Patients

NCT06737380

Recruiting

The goal of this clinical trial is to evaluate the safety and effectiveness of UC-MSCs in adults with systemic lupus erythematosus (SLE). The main questions this study aims to answer are: 1. Can UC-MSCs improve kidney function and reduce SLE disease activity? 2. Are UC-MSCs safe and well-tolerated in this patient population? Participants in this study will: * Receive UC-MSCs in a single dose in addition to standard of care treatment. * Provide blood and urine samples for laboratory assessmen... Read More

Gender:

ALL

Ages:

Between 18 years and 75 years

Trial Updated:

08/03/2025

Locations: Medical University of South Carolina, Charleston, South Carolina

Conditions: SLE, Lupus, Systemic Lupus Erthematosus, Systemic Lupus Erythematosus, Systemic Lupus Erythematosus (SLE)

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Prospective Registry Investigating Maternal and Infant Outcomes in Anifrolumab Users

NCT06659029

Recruiting

PRIMULA Preg (Prospective Registry Investigating Maternal and Infant Outcomes in Anifrolumab Users) is a prospective, observational cohort study designed to evaluate the association between anifrolumab exposure during pregnancy and subsequent adverse maternal, fetal, and infant outcomes. This study will fulfil an FDA post-marketing requirement.

Gender:

FEMALE

Ages:

All

Trial Updated:

07/29/2025

Locations: Research Site, Las Vegas, Nevada

Conditions: Systemic Lupus Erythematosus

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Phase 3 Extension Study to Evaluate Long-term Safety of Ianalumab in Participants With Systemic Lupus Erythematosus (SIRIUS-SLE Extension).

NCT06133972

Recruiting

The purpose of this study is to evaluate long-term safety and tolerability of ianalumab in participants with systemic lupus erythematosus who have previously completed the treatment period in one of the two SIRIUS-SLE core studies (CVAY736F12301 or CVAY736F12302).

Gender:

ALL

Ages:

Between 12 years and 100 years

Trial Updated:

07/29/2025

Locations: Pinnacle Research Group Llc, Anniston, Alabama +79 locations

Pinnacle Research Group Llc, Anniston, Alabama

Advanced Medical Research, La Palma, California

Millennium Clinical Trials, Westlake Village, California

Clinical Res Of W Florida, Clearwater, Florida

Accurate Clinical Research, Lake Charles, Louisiana

University Of Maryland Med Ctr, Baltimore, Maryland

Ahmed Arif Medical Research Center, Grand Blanc, Michigan

West Tennessee Research Institute, Jackson, Tennessee

Shelby Research LLC, Memphis, Tennessee

Novel Research LLC, Bellaire, Texas

Novartis Investigative Site, Ciudad Autonoma de Bs As, Buenos Aires

Novartis Investigative Site, San Miguel, Buenos Aires

Novartis Investigative Site, San Miguel de Tucuman, Tucuman

Novartis Investigative Site, Tucuman, Not set

Novartis Investigative Site, Maroochydore, Queensland

Novartis Investigative Site, Salvador, BA

Novartis Investigative Site, Belo Horizonte, MG

Novartis Investigative Site, Barretos, Sao Paulo

Novartis Investigative Site, Sao Paulo, SP

Novartis Investigative Site, Plovdiv, Not set

Novartis Investigative Site, Rimouski, Quebec

Novartis Investigative Site, Guangzhou, Guangdong

Novartis Investigative Site, Shantou, Guangdong

Novartis Investigative Site, Nanjing, Jiangsu

Novartis Investigative Site, Suzhou, Jiangsu

Novartis Investigative Site, Nanchang, Jiangxi

Novartis Investigative Site, Pingxiang, Jiangxi

Novartis Investigative Site, Chang Chun, Jilin

Novartis Investigative Site, Linyi, Shandong

Novartis Investigative Site, Urumqi, Xinjiang

Novartis Investigative Site, Beijing, Not set

Novartis Investigative Site, Shanghai, Not set

Novartis Investigative Site, Zhejiang, Not set

Novartis Investigative Site, Medellin, Antioquia

Novartis Investigative Site, Barranquilla, Atlantico

Novartis Investigative Site, Chia, Cundinamarca

Novartis Investigative Site, Bucaramanga, Santander

Novartis Investigative Site, Bogota, Not set

Novartis Investigative Site, Brno, Not set

Novartis Investigative Site, Uherske Hradiste, Not set

Novartis Investigative Site, Montpellier 5, Not set

Novartis Investigative Site, Paris, Not set

Novartis Investigative Site, Leipzig, Sachsen

Novartis Investigative Site, Guatemala City, Not set

Novartis Investigative Site, Guatemala, Not set

Novartis Investigative Site, Szekesfehervar, Fejer

Novartis Investigative Site, Ahmedabad, Gujarat

Novartis Investigative Site, Ramat Gan, Not set

Novartis Investigative Site, Torino, TO

Novartis Investigative Site, Nagoya, Aichi

Novartis Investigative Site, Sapporo city, Hokkaido

Novartis Investigative Site, Seoul, Seocho Gu

Novartis Investigative Site, Seoul, Not set

Novartis Investigative Site, Ipoh, Perak

Novartis Investigative Site, Ciudad de Mexico, Distrito Federal

Novartis Investigative Site, Leon, Guanajuato

Novartis Investigative Site, Guadalajara, Jalisco

Novartis Investigative Site, Merida, Yucatan

Novartis Investigative Site, Mexico, Not set

Novartis Investigative Site, Wroclaw, Dolnoslaskie

Novartis Investigative Site, Bydgoszcz, Not set

Novartis Investigative Site, Bytom, Not set

Novartis Investigative Site, Warszawa, Not set

Novartis Investigative Site, Braga, Not set

Novartis Investigative Site, Brasov, Not set

Novartis Investigative Site, Cluj Napoca, Not set

Novartis Investigative Site, Santander, Cantabria

Novartis Investigative Site, Badalona, Catalunya

Novartis Investigative Site, Barcelona, Catalunya

Novartis Investigative Site, Santiago De Compostela, Galicia

Novartis Investigative Site, Madrid, Not set

Novartis Investigative Site, Kaohsiung, Not set

Novartis Investigative Site, Taichung, Not set

Novartis Investigative Site, Taoyuan, Not set

Novartis Investigative Site, Bangkok, Not set

Conditions: Systemic Lupus Erythematosus

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A Study Describing the Efficacy and Safety of Belimumab Administered in Adult Participants With Early Systemic Lupus Erythematosus (SLE)

NCT06411249

Recruiting

This is a prospective, open-label, single arm 3-year clinical study to describe the short-term and long-term efficacy and safety of belimumab in participants with autoantibody positive early SLE with ongoing disease activity despite stable initial SLE therapy.

Gender:

ALL

Ages:

18 years and above

Trial Updated:

07/28/2025

Locations: GSK Investigational Site, Anniston, Alabama +99 locations

GSK Investigational Site, Anniston, Alabama

GSK Investigational Site, Flagstaff, Arizona

GSK Investigational Site, Mesa, Arizona

GSK Investigational Site, Tucson, Arizona

GSK Investigational Site, Covina, California

GSK Investigational Site, Fontana, California

GSK Investigational Site, Fullerton, California

GSK Investigational Site, Long Beach, California

GSK Investigational Site, Los Angeles, California

GSK Investigational Site, Mission Hills, California

GSK Investigational Site, San Diego, California

GSK Investigational Site, Tujunga, California

GSK Investigational Site, Van Nuys, California

GSK Investigational Site, Whittier, California

GSK Investigational Site, Aventura, Florida

GSK Investigational Site, Clearwater, Florida

GSK Investigational Site, Miami, Florida

GSK Investigational Site, Tamarac, Florida

GSK Investigational Site, Tampa, Florida

GSK Investigational Site, Atlanta, Georgia

GSK Investigational Site, Sugar Hill, Georgia

GSK Investigational Site, Morton Grove, Illinois

GSK Investigational Site, Rockford, Illinois

GSK Investigational Site, Baton Rouge, Louisiana

GSK Investigational Site, Shreveport, Louisiana

GSK Investigational Site, Lansing, Michigan

GSK Investigational Site, Sparta, New Jersey

GSK Investigational Site, Charlotte, North Carolina

GSK Investigational Site, Duncansville, Pennsylvania

GSK Investigational Site, Philadelphia, Pennsylvania

GSK Investigational Site, Austin, Texas

GSK Investigational Site, Baytown, Texas

GSK Investigational Site, Colleyville, Texas

GSK Investigational Site, Fort Worth, Texas

GSK Investigational Site, Houston, Texas

GSK Investigational Site, Katy, Texas

GSK Investigational Site, Plano, Texas

GSK Investigational Site, Waco, Texas

GSK Investigational Site, Danville, Virginia

GSK Investigational Site, Glendale, Wisconsin

GSK Investigational Site, Berazategui, Not set

GSK Investigational Site, Buenos Aires, Not set

GSK Investigational Site, Ciudad Autonoma Buenos Aires, Not set

GSK Investigational Site, Ciudad Autonoma de Buenos Aires, Not set

GSK Investigational Site, Ciudad Autonoma de Buenos Aire, Not set

GSK Investigational Site, La Plata, Not set

GSK Investigational Site, Mar del Plata, Not set

GSK Investigational Site, Quilmes, Not set

GSK Investigational Site, Santa Fe, Not set

GSK Investigational Site, Tucuman, Not set

GSK Investigational Site, Belo Horizonte, Not set

GSK Investigational Site, Cuiaba, Not set

GSK Investigational Site, Juiz de Fora, Not set

GSK Investigational Site, Passo Fundo, Not set

GSK Investigational Site, Porto Alegre, Not set

GSK Investigational Site, Salvador, Not set

GSK Investigational Site, Sao Jose Do Rio Preto, Not set

GSK Investigational Site, Sao Paulo, Not set

GSK Investigational Site, SAo Paulo, Not set

GSK Investigational Site, Angers Cedex 9, Not set

GSK Investigational Site, Lille cedex, Not set

GSK Investigational Site, Pessac, Not set

GSK Investigational Site, Rennes, Not set

GSK Investigational Site, Saint-Priest en Jarez, Not set

GSK Investigational Site, Toulouse Cedex 9, Not set

GSK Investigational Site, Herne, Not set

GSK Investigational Site, Luebeck, Not set

GSK Investigational Site, Mainz, Not set

GSK Investigational Site, Meerbusch, Not set

GSK Investigational Site, Athens, Not set

GSK Investigational Site, Heraklion, Not set

GSK Investigational Site, Thessaloniki, Not set

GSK Investigational Site, Brescia, Not set

GSK Investigational Site, Ferrara, Not set

GSK Investigational Site, Pisa, Not set

GSK Investigational Site, Reggio Emilia, Not set

GSK Investigational Site, Rome, Not set

GSK Investigational Site, Rozzano, Not set

GSK Investigational Site, Fukuoka, Not set

GSK Investigational Site, Kanagawa, Not set

GSK Investigational Site, Miyagi, Not set

GSK Investigational Site, Osaka, Not set

GSK Investigational Site, Tokyo, Not set

GSK Investigational Site, LeOn Guanajuato, Not set

GSK Investigational Site, Merida, Not set

GSK Investigational Site, Mexico DF, Not set

GSK Investigational Site, Monterrey Nuevo LeOn, Not set

GSK Investigational Site, Barcelona, Not set

GSK Investigational Site, COrdoba, Not set

GSK Investigational Site, Murcia, Not set

GSK Investigational Site, Sevilla, Not set

GSK Investigational Site, Valladolid, Not set

GSK Investigational Site, VigoPontevedra, Not set

GSK Investigational Site, Villajoyosa, Not set

Conditions: Systemic Lupus Erythematosus

Learn More ›

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