There are currently 45 active clinical trials seeking participants for Systemic Lupus Erythematosus research studies. The states with the highest number of trials for Autism participants are California, Florida, Texas and New York.
Lupus Education Alliance Program
Recruiting
The purpose of this study is to evaluate the evaluate the effect of education-only vs. navigation interventions on COVID-19 testing and vaccination for people with systemic lupus erythematosus.
Gender:
All
Ages:
18 years and above
Trial Updated:
11/27/2023
Locations: Tulane University, New Orleans, Louisiana
Conditions: Systemic Lupus Erythematosus, COVID-19
Systemic Lupus Erythematosus in Gullah Health
Recruiting
Systemic lupus erythematosus (SLE) is an autoimmune disease characterized by the production of autoantibodies, multiple organ involvement, and diverse clinical symptoms and immunologic manifestations. African Americans are at a disproportionately higher risk of developing SLE, develop SLE at an earlier age, and have increased morbidity and mortality compared with European Americans. Our central study hypothesis is that there are specific genetic factors that interact with environmental exposures... Read More
Gender:
All
Ages:
2 years and above
Trial Updated:
11/19/2023
Locations: Medical University of South Carolina, Charleston, South Carolina
Conditions: Systemic Lupus Erythematosus
A Study of Telitacicept for the Treatment of Moderately to Severely Active Systemic Lupus Erythematosus (REMESLE-1)
Recruiting
The purpose of this study is to evaluate the efficacy and safety of telitacicept in the treatment of moderately to severely active SLE.
Gender:
All
Ages:
Between 12 years and 70 years
Trial Updated:
11/16/2023
Locations: Anniston, Alabama Site, Anniston, Alabama +88 locations
Conditions: Systemic Lupus Erythematosus
Testing of an Educational Tool for Patients With Melanoma and Pre-Existing Autoimmune Disease Who Are Candidates for Immune Checkpoint Inhibitors
Recruiting
This study learn how easily patients can use an educational tool that will be created for patients with melanoma and pre-existing autoimmune diseases who receive or will receive immune checkpoint inhibitor drugs. Patients will be asked their opinions about the design, accessibility, and content of the tool. Researchers will use the information collected to improve the educational materials that will help patients make future decisions about their treatment.
Gender:
All
Ages:
18 years and above
Trial Updated:
09/12/2023
Locations: M D Anderson Cancer Center, Houston, Texas
Conditions: Ankylosing Spondylitis, Autoimmune Disease, Crohn Disease, Inflammatory Bowel Disease, Melanoma, Psoriasis, Psoriatic Arthritis, Reactive Arthritis, Rheumatoid Arthritis, Systemic Lupus Erythematosus, Ulcerative Colitis, Enteropathic Arthritis, Enteropathic Spondylitis
LUPUS Brain: tACS to Target the Neurophysiology of Depression, Cognitive Deficits, and Pain in Patients With SLE
Recruiting
The purpose of this study is to investigate the effects of a type of non-invasive transcranial alternating current stimulation (tACS) on patients diagnosed with systemic lupus erythematosus (SLE) who are experiencing depression. Targeting depression in patients with SLE may provide benefit to these patients, as there is a clear relationship between chronic pain and depression. The investigators propose that a tACS stimulation montage that was previously used in depression could be beneficial to... Read More
Gender:
All
Ages:
Between 18 years and 65 years
Trial Updated:
06/28/2023
Locations: University of North Carolina at Chapel Hill, Chapel Hill, North Carolina
Conditions: Systemic Lupus Erythematosus, Depression
A Study in Participants With Mild-to-moderate Systemic Lupus Erythematosus
Recruiting
The main purpose of this study is to evaluate the safety and tolerability of CUG252 following multiple ascending doses in participants with Systemic Lupus Erythematosus (SLE).
Gender:
All
Ages:
Between 18 years and 65 years
Trial Updated:
05/10/2023
Locations: Site 1001, Anniston, Alabama +10 locations
Conditions: Systemic Lupus Erythematosus, SLE (Systemic Lupus), Autoimmune
Stress, Inflammation and Immune Response Pilot Study- Aim 3
Recruiting
The overall goal of this study is to investigate the effects of stress and glucose intake at the molecular level including gene expression, protein and functional analysis of immune cells in real time. Aim 1- Characterizing the immune response after acute stress and glucose consumption Aim 2- Temporal mapping of the modulation of immune cell function via meditation Aim 3-Influence of meditative practice on lupus patients Aim 4-Influence of meditative practice on healthy subjects Current Clinic... Read More
Gender:
Female
Ages:
Between 21 years and 65 years
Trial Updated:
03/27/2023
Locations: University of Wisconsin, Madison, Wisconsin
Conditions: Systemic Lupus Erythematosus, Inflammation
Development of a Therapeutic Endpoint in Pediatric Rheumatologic Conditions
Recruiting
The overarching goal of this study is the development of a physiologic endpoint of pain and treatment effect in three distinct rheumatology populations. This would enable objective assessment of pain and treatment in these populations and enable a much more precise approach to treatment. Such an endpoint stands to significantly improve outcomes in these patients by eliminating the need for a trial-and-error approach to treatment. This is a single site observational study that aims to collect ini... Read More
Gender:
All
Ages:
Between 5 years and 21 years
Trial Updated:
01/31/2023
Locations: Children's National Health System, Washington, District of Columbia
Conditions: Juvenile Idiopathic Arthritis, Systemic Lupus Erythematosus, Fibromyalgia
Duke Lupus Registry
Recruiting
Lupus is a systemic autoimmune disease that can present with many varied symptoms, including joint pain, fevers, kidney disease, and rashes. Lupus can affect anyone, but it is most common in younger women. The Duke Lupus Registry will collect information and blood samples from patients with lupus (systemic lupus erythematosus or cutaneous lupus) seen in the Duke Rheumatology clinics. The goal of this Registry is to understand how lupus changes over time so that we can improve the treatment of p... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
12/19/2022
Locations: Duke University Medical Center, Durham, North Carolina
Conditions: Systemic Lupus Erythematosus, Cutaneous Lupus