There are currently 44 active clinical trials seeking participants for Systemic Lupus Erythematosus research studies. The states with the highest number of trials for Systemic Lupus Erythematosus participants are California, Florida, Texas and New York.
Examining Distinct Immunophenotypes to Validate and Enhance Rational Treatment in Systemic Lupus
NCT05306873
Recruiting
The primary purpose of this study is to evaluate the potential effectiveness of 24 weeks of MMF within previously discovered immunologically defined subsets of SLE patients. Treatment effects will be evaluated within the individual immunologically-homogenous subsets defined at screening. This study will also explore and compare pre-randomization gene expression patterns among responders and non-responders to MMF and MMF plus voclosporin, use comprehensive immunophenotyping to study the immunolog... Read More
Gender:
All
Ages:
Between 18 years and 60 years
Trial Updated:
01/18/2024
Locations: UCLA Medical Center: Division of Rheumatology, Los Angeles, California +10 locations
Conditions: Systemic Lupus Erythematosus
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Rheumatology Patient Registry and Biorepository
NCT04402086
Recruiting
To facilitate clinical, basic science, and translational research projects involving the study of rheumatic diseases.
Gender:
All
Ages:
Between 18 years and 99 years
Trial Updated:
12/21/2023
Locations: Yale New Haven Hospital, New Haven, Connecticut
Conditions: Rheumatic Diseases, Adult Onset Still Disease, Ankylosing Spondylitis, Psoriatic Arthritis, Reactive Arthritis, Antiphospholipid Syndrome, Systemic Lupus Erythematosus, Behcet Disease, Dermatomyositis, Polymyositis, Giant Cell Arteritis, Lyme Disease, Mixed Connective Tissue Disease, Polymyalgia Rheumatica, Rheumatoid Arthritis, Sarcoidosis, Systemic Sclerosis, Scleroderma, Sjogren's Syndrome, Undifferentiated Connective Tissue Diseases
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Lupus Education Alliance Program
NCT05243875
Recruiting
The purpose of this study is to evaluate the evaluate the effect of education-only vs. navigation interventions on COVID-19 testing and vaccination for people with systemic lupus erythematosus.
Gender:
All
Ages:
18 years and above
Trial Updated:
11/27/2023
Locations: Tulane University, New Orleans, Louisiana
Conditions: Systemic Lupus Erythematosus, COVID-19
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Systemic Lupus Erythematosus in Gullah Health
NCT00756769
Recruiting
Systemic lupus erythematosus (SLE) is an autoimmune disease characterized by the production of autoantibodies, multiple organ involvement, and diverse clinical symptoms and immunologic manifestations. African Americans are at a disproportionately higher risk of developing SLE, develop SLE at an earlier age, and have increased morbidity and mortality compared with European Americans. Our central study hypothesis is that there are specific genetic factors that interact with environmental exposures... Read More
Gender:
All
Ages:
2 years and above
Trial Updated:
11/19/2023
Locations: Medical University of South Carolina, Charleston, South Carolina
Conditions: Systemic Lupus Erythematosus
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A Study of Telitacicept for the Treatment of Moderately to Severely Active Systemic Lupus Erythematosus (REMESLE-1)
NCT05306574
Recruiting
The purpose of this study is to evaluate the efficacy and safety of telitacicept in the treatment of moderately to severely active SLE.
Gender:
All
Ages:
Between 12 years and 70 years
Trial Updated:
11/16/2023
Locations: Anniston, Alabama Site, Anniston, Alabama +88 locations
Conditions: Systemic Lupus Erythematosus
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A Study in Participants With Mild-to-moderate Systemic Lupus Erythematosus
NCT05866861
Recruiting
The main purpose of this study is to evaluate the safety and tolerability of CUG252 following multiple ascending doses in participants with Systemic Lupus Erythematosus (SLE).
Gender:
All
Ages:
Between 18 years and 65 years
Trial Updated:
05/10/2023
Locations: Site 1001, Anniston, Alabama +10 locations
Conditions: Systemic Lupus Erythematosus, SLE (Systemic Lupus), Autoimmune
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Development of a Therapeutic Endpoint in Pediatric Rheumatologic Conditions
NCT04833465
Recruiting
The overarching goal of this study is the development of a physiologic endpoint of pain and treatment effect in three distinct rheumatology populations. This would enable objective assessment of pain and treatment in these populations and enable a much more precise approach to treatment. Such an endpoint stands to significantly improve outcomes in these patients by eliminating the need for a trial-and-error approach to treatment. This is a single site observational study that aims to collect ini... Read More
Gender:
All
Ages:
Between 5 years and 21 years
Trial Updated:
01/31/2023
Locations: Children's National Health System, Washington, District of Columbia
Conditions: Juvenile Idiopathic Arthritis, Systemic Lupus Erythematosus, Fibromyalgia
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Duke Lupus Registry
NCT00512694
Recruiting
Lupus is a systemic autoimmune disease that can present with many varied symptoms, including joint pain, fevers, kidney disease, and rashes. Lupus can affect anyone, but it is most common in younger women. The Duke Lupus Registry will collect information and blood samples from patients with lupus (systemic lupus erythematosus or cutaneous lupus) seen in the Duke Rheumatology clinics. The goal of this Registry is to understand how lupus changes over time so that we can improve the treatment of p... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
12/19/2022
Locations: Duke University Medical Center, Durham, North Carolina
Conditions: Systemic Lupus Erythematosus, Cutaneous Lupus
Register for Updates