Somatosensory Tinnitus RCT
NCT05434637
Recruiting
The purpose of this study is to learn more about a type of tinnitus (ringing in the ears) known as "somatosensory tinnitus." This type of tinnitus is suspected when the tinnitus perception changes following head and/or neck movements. This study is also exploring a possible way to treat somatosensory tinnitus.
Gender:
All
Ages:
18 years and above
Trial Updated:
11/03/2023
Locations: VA Portland Health Care System, Portland, OR, Portland, Oregon
Conditions: Tinnitus
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An fMRI Investigation of the Effects of IV Lidocaine on Tinnitus
NCT04192773
Recruiting
This is an exploratory pilot open-label study to identify the signal changes on fMRI of patients with tinnitus and with temporary suppression of the tinnitus with IV lidocaine. Patients will include those with hearing loss (both unilateral and bilateral) and tinnitus, subjects with normal hearing and tinnitus, and control subjects with normal hearing and no tinnitus. Eligible subjects will have functional and subjective data collected at baseline, receive an IV lidocaine infusion, and have funct... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
10/17/2023
Locations: Massachusetts Eye and Ear Infirmary, Boston, Massachusetts
Conditions: Tinnitus
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An Open-Label Study Evaluating Brexanolone in Adults With Tinnitus
NCT05645432
Recruiting
The primary objective of this study is to evaluate the safety and tolerability of brexanolone in participants with tinnitus following a single 6-hour continuous intravenous (IV) infusion.
Gender:
All
Ages:
Between 18 years and 65 years
Trial Updated:
10/17/2023
Locations: Sage Investigational Site, Atlanta, Georgia +1 locations
Conditions: Tinnitus
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Neurobiological Similarities of Tinnitus and PTSD
NCT05981391
Recruiting
Psychiatric distress caused by PTSD may increase attention toward tinnitus, as well as perceived loudness and discomfort. It is important to understand how tinnitus-related distress and PTSD negatively interact together, in order to develop more effective therapeutic approaches. Understanding symptoms and neurobiological mechanisms using functional magnetic resonance imaging (fMRI), can lead to the necessary knowledge to develop effective interventions for individuals who suffer from both condit... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
08/07/2023
Locations: UT Health San Antonio, San Antonio, Texas
Conditions: Posttraumatic Stress Disorder, Tinnitus
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The Efficacy of Incobotulinum Toxin A Injections for Treatment of Tinnitus: a Randomized Controlled Trial
NCT05650645
Recruiting
Tinnitus is a persistent non-physiologic, non-psychiatric, ringing in the ear that affects up to 20% of the general US population. The purpose of this study is to assess the patient reported effectiveness of Xeomin (incobotulinumtoxinA) injections into the auricular muscles for relief of tinnitus with use of the Tinnitus Handicap Inventory questionnaire.
Gender:
All
Ages:
18 years and above
Trial Updated:
07/24/2023
Locations: University of Minnesota, Minneapolis, Minnesota
Conditions: Tinnitus
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Acoustic and Electrical Stimulation for the Treatment of Tinnitus
NCT03511807
Recruiting
Tinnitus, or ringing in the ears, affects 10% to 30% of the population. Of those, 20% have tinnitus bothersome enough to seek medical attention. In many people, tinnitus can significantly affect the quality of life. At this point in time, there is no effective treatment or cure available for tinnitus. It has been found that electrical stimulation of the inner ear can reduce and in some cases eliminate tinnitus. The purpose of this research is to investigate both acoustic and electrical stimulat... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
06/30/2023
Locations: Hamid R. Djalilian, Irvine, California
Conditions: Tinnitus
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Treatment of Tinnitus With Migraine Medications
NCT04404439
Recruiting
Tinnitus represents one of the most common and distressing otologic problems, and it causes various somatic and psychological disorders that interfere with the quality of life. It is well-understood that many factors, such as poor education, lower income, or occupational, and recreational activity associated with high noise exposure, influences the prevalence and risk of tinnitus. Although the economic and emotional impact of tinnitus is large, there is currently no FDA-approved medication to tr... Read More
Gender:
All
Ages:
Between 25 years and 85 years
Trial Updated:
01/06/2023
Locations: University of California, Irvine Medical Center ENT Clinic (Pavilion 2), Orange, California
Conditions: Tinnitus, Subjective, Tinnitus
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