The state of Florida currently has 32 active clinical trials seeking participants for Osteoarthritis research studies. These trials are conducted in various cities, including Miami, Tampa, Jacksonville and Orlando.
Pre vs Post Block in Total Knee Arthroplasty (TKA)
NCT05974501
Recruiting
The purpose of this project is to determine if a change in patient reported pain, nausea and vomiting after total knee arthroplasty can be observed with the substitution of a post operative adductor canal block for a preoperative adductor canal block in the current established peri-operative pain protocol and if these changes lead to a decrease in opioid consumption (in morphine equivalents).
Gender:
All
Ages:
18 years and above
Trial Updated:
09/30/2023
Locations: University of Miami, Miami, Florida
Conditions: Knee Osteoarthritis, Arthroplasty Complications, Postoperative Pain
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Open-label Trial to Check the Safety and Tolerability of RTX-GRT7039 Injections for Pain Associated With Osteoarthritis of the Knee
NCT05377489
Recruiting
An open-label, single-arm clinical trial to confirm the safety of monoarticular injections or bi-lateral intra-articular injections of RTX-GRT7039 in patients who have pain associated with osteoarthritis of the knee despite standard of care.
Gender:
All
Ages:
18 years and above
Trial Updated:
09/25/2023
Locations: Progressive Medical Research, Port Orange, Florida +2 locations
Conditions: Osteoarthritis
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Pain Relief for OsteoArthritis Through Combined Treatment (PROACT)
NCT03884374
Recruiting
This mechanistic clinical trial proposes to test whether a five-day course of mindfulness meditation training (MMT) and tDCS, and their combination, can enhance pain modulatory balance and pain-related brain function, reduce clinical pain, among African Americans and non-Hispanic whites with knee osteoarthritis (OA). This approach will provide evidence that targeting stress and pain-related brain function will reduce OA-related pain and ethnic group differences therein.
Gender:
All
Ages:
Between 45 years and 85 years
Trial Updated:
09/18/2023
Locations: University of Florida, Gainesville, Florida
Conditions: Osteoarthritis of Knee
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Autologous Adipose-derived Stromal Vascular Fraction for Treatment of Knee Osteoarthritis
NCT04440189
Recruiting
This study is a pivotal study to evaluate the efficacy and safety of a single injection of autologous adipose-derived SVF produced using the GID SVF-2 device system for treatment of pain with concomitant improvement in function associated with osteoarthritis of the knee joint.
Gender:
All
Ages:
Between 35 years and 85 years
Trial Updated:
09/07/2023
Locations: Advanced Research LLC, Coral Springs, Florida +1 locations
Conditions: Osteoarthritis, Knee
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Clinical Orthopaedic Data Bank (Acute and Chronic)
NCT00411060
Recruiting
Data involving orthopaedic conditions and rehabilitation aspects of musculoskeletal and neuromuscular disorders will be collected and stored as part of the normal clinical care of patients seen in the University of Florida (UF) and Shands Orthopaedics and Sports Medicine Institute.
Gender:
All
Ages:
All
Trial Updated:
07/24/2023
Locations: UF&Shands Orthopaedics and Sports Medicine Institute, Gainesville, Florida
Conditions: Osteoarthritis, Osteosarcoma, Scoliosis, Cerebral Palsy
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Optimal Anesthetic for Corticosteroid Injections for Knee Osteoarthritis
NCT05906433
Recruiting
To evaluate pain relief from corticosteroid injection with and without anesthetic as well as with variable volume of anesthetic. Pain relief will be measured using the VAS pain score at the time of the injection as well as several time points following the injection to capture pain relief longevity. The investigators intend to evaluate how well the patients tolerate corticosteroid mixtures without anesthetic as well as with different volumes of anesthetic. Primary measure will be the time from p... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
06/13/2023
Locations: Florida Orthopaedic Institute, Tampa, Florida
Conditions: Knee Osteoarthritis
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Physica System Total Knee Replacement Registry Study
NCT03048201
Recruiting
The primary objective of this study is to obtain long-term implant survivorship (out to 10 years) and to assess clinical, patient-reported outcome measures, and radiographic data for the commercially available Physica system. For ancillary arm, from baseline to 5-year follow-up.
Gender:
All
Ages:
22 years and above
Trial Updated:
03/17/2023
Locations: The Orthopedics Clinic, Daytona Beach, Florida
Conditions: Osteoarthritis, Knee, Traumatic Arthritis, Avascular Necrosis, Degenerative Joint Disease of Knee, Rheumatoid Arthritis, Deformity of Knee
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Thumb Osteoarthritis Mechanisms
NCT04104477
Recruiting
This study examines carpometacarpal osteoarthritis (CMC OA) and aims to elucidate the biomechanical, neuromuscular, and somatosensory mechanisms that contribute to CMC OA symptoms by using orthopaedic biomechanics and quantitative pain testing. Completion of this study will provide a comprehensive dataset describing how movement strategies (muscle activity and joint posture) as well as experimental and clinical pain differ between individuals with CMC OA and age-matched controls.
Gender:
Female
Ages:
Between 40 years and 90 years
Trial Updated:
11/21/2022
Locations: UF Health of University of Florida, Gainesville, Florida
Conditions: Carpometacarpal Osteoarthritis
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